Since August 2010 benzidine dyes are included in the EPA's List of Chemicals of Concern. (t3db.ca)
7] demonstrated that acidic urine pH increased the level of both free ABZ and the dGp-ABZ adduct in exfoliated urothelial cells of workers exposed to benzidine and benzidine-based dyes, and that ABZ strongly correlated with adduct levels. (cdc.gov)
Bladder4
Benzidine has been linked to bladder and pancreatic cancer. (t3db.ca)
Reply to the letter to the editor: N-Acetyltransferases and the susceptibility to benzidine-induced bladder carcinogenesis. (cdc.gov)
We thank Drs. Wang and King for their interest in our article on NAT2 acetylation and bladder cancer risk in workers exposed to benzidine. (cdc.gov)
5] Drs. Wang and King have suggested that N-hydroxy-N-glucuronide-N-acetylbenzidine is likely to play a central role in benzidine bladder carcinogenesis, based on their findings in the rat heterotopic bladder model. (cdc.gov)
Workers3
1993. Decrease of CD4-positive T lymphocytes in workers exposed to benzidine and beta-naphthylamine. (cdc.gov)
3] As we noted in our article,[1] the apparent contradiction is explainable, at least in part, by the fact that workers in that report are likely to have been exposed to 2-naphthylamine, a monoarylamine, as well as to benzidine, a diarylamine (unpublished findings). (cdc.gov)
3] In contrast, workers in the factories we studied were exposed primarily to benzidine and related compounds. (cdc.gov)
Activity2
UDS activity in the rat liver of the human carcinogens benzidine and 4-aminobiphenyl, and the rodent carcinogens 3,3'-dichlorobenzidine and direct black 38. (cdc.gov)
3] Drs. Wang and King question our comments on the role of peroxidatic activity of prostaglandin H synthase (PHS) in benzidine carcinogenesis. (cdc.gov)
Based on this, two carbazoles and two phenyl benzidines are feasible compounds with semiconductor capacity to be used in solar cells. (crimsonpublishers.com)
The thermal results of the analyzed compounds show that the phenyl benzidine derivatives have a higher molar heat capacity, which is related to the resonance capacity of the electron density of the conjugated double bonds to generate electron density tubes in the in-phase structures solid (Figure 1). (crimsonpublishers.com)
Carcinogens2
UDS activity in the rat liver of the human carcinogens benzidine and 4-aminobiphenyl, and the rodent carcinogens 3,3'-dichlorobenzidine and direct black 38. (cdc.gov)
From the accumulated evidence, OSHA and NIOSH conclude that benzidine-based dyes are potential human carcinogens. (cdc.gov)
Substances5
The human health assessment for Benzidine-based Dyes and Related Substances focuses on substances that are in commerce (based on information received in response to the section 71 survey) and/or for which available information indicates potential exposure to the general population of Canada: 3,3'-DMB and Acid Red 97. (gc.ca)
Based on the uses of these substances and the overall low volumes of Benzidine-based Substances or Benzidine Derivatives in commerce, exposure from environmental media is not expected. (gc.ca)
As none of the substances in this assessment were identified to be used in food packaging or food-related applications, these sources are not considered to contribute to exposure to Benzidine-based Substances or Benzidine Derivatives. (gc.ca)
The presence of other Benzidine-based Substances or Benzidine Derivatives in products, in particular in textiles, in Canada has not been identified. (gc.ca)
Benzidine-based dyes may contain residual amounts of benzidine as well as other substances such as 4-aminobiphenyl, an OSHA-regulated carcinogen. (cdc.gov)
Abstract1
1984. Covalent binding of benzidine to rat hemoglobin [Abstract]. (cdc.gov)
Environmental1
In vitro evaluation of some derivatives of the carcinogen butter yellow: Implications for environmental screening. (cdc.gov)