• The combination of levodopa, decarboxylase inhibitor and COMT inhibitor is classified in N04BA - Dopa and dopa derivatives. (whocc.no)
  • Unfortunately, flu strains resistant to adamantane derivatives have become increasingly common. (chemistryworld.com)
  • Influenza A variants with reduced in vitro sensitivity to amantadine have been isolated from epidemic strains in areas where adamantane derivatives are being used. (nih.gov)
  • How to overcome resistance of influenza A viruses against adamantane derivatives. (cdc.gov)
  • However, tackling flu - or to be precise, the Influenza A virus - is just the beginning of the medical capability of adamantane derivatives. (chemistryworld.com)
  • Compounds possessing mirror symmetry are always optically inactive, such as, for example, cis - and trans -1,4-disubstituted cyclohexane derivatives, or symmetrically cis -1,2-disubstituted cyclohexanes (see also the 3D structures at 'Cycloalkanes' ). (tu-darmstadt.de)
  • The simplest members are cyclopropane (C3H6), cyclobutane (C4H8), cyclohexane (C6H12), and derivatives of these such as methylcyclohexane (C6H11CH3). (bvsalud.org)
  • The Synthesis and Characterization of 4-Isopropylanilino Derivatives of Cyclotriphosphazene. (gtu.edu.tr)
  • Cyclotriphosphazene derivatives with three different chiral centres: Synthesis, characterization and investigation of their stereogenic properties. (gtu.edu.tr)
  • In that context, this project aims at the synthesis, optimization and characterization of new Ag(I), Pd(II) and Pt(II) complexes using as ligand the drugs D-cycloserine and kanamycin A, that are used for Tuberculosis therapy, and also some derivatives of anthranilic acid that have high activity against Mycobacterium tuberculosis. (fapesp.br)
  • A whole string of compounds have been built on the adamantane structure, starting in 1967 with adamantadine - simply adamantane with one hydrogen replaced by ammonia. (chemistryworld.com)
  • New oxathiazin-like compounds and their derivatives are useful as antineoplastic and antimicrobial agents. (justia.com)
  • A colourless crystal at room temperature with a camphor-like smell, adamantane is an alkane with the formula C 10 H 16 , consisting of three linked rings, producing that diamond-like molecular structure. (chemistryworld.com)
  • Stereogenic Properties of 1,3-Disubstituted Derivatives of Cyclotriphosphazene: - cis(meso) and trans(racemic) Isomers. (gtu.edu.tr)
  • Bromantane, sold under the brand name Ladasten, is an atypical psychostimulant and anxiolytic drug of the adamantane family related to amantadine and memantine which is used in Russia in the treatment of neurasthenia. (wikipedia.org)
  • Other derivatives have also proved effective antivirals, as they can block an ion channel - a chemical communication route in the cell that is used in replicating the virus and which ceases to function when blocked by the drug. (chemistryworld.com)
  • However, adamantane provides a starting point for the production of larger molecules, particularly medicinal drugs. (chemistryworld.com)
  • It is this same ability that helps adamantane-based drugs to cross the blood-brain barrier to work in neurological disorders such as Parkinson's and Alzheimer's. (chemistryworld.com)
  • It belongs to a class of drugs known as adamantane derivatives, and it primarily affects the central nervous system. (v-carepharmacy.com)
  • Early methods of production involved complicated routes from larger organic molecules, but since the 1950s it has been produced from the naptha derivative dicyclopentadiene, in a two-stage catalysed hydrogenation and restructuring process. (chemistryworld.com)
  • In general, the invention relates to a process for the preparation of acesulfame or a derivative thereof. (justia.com)
  • More specifically, the invention relates to a process, to a product obtainable by the process and the use of a specified velocity of flow for improving yield in the preparation of acesulfame or a derivative thereof. (justia.com)
  • The invention relates to a process for the preparation of a product, the product being 6-methyl-3,4-dihydro1,2,3-oxathiazin-4-one 2,2-dioxide or a derivative thereof, the process comprising the following steps: a. (justia.com)
  • The novel structure of adamantane, which is the hallmark of all its derivatives, gives it impressive properties. (chemistryworld.com)
  • The investigation of stereogenic properties of cyclotriphosphazene derivatives with two different chiral centres. (gtu.edu.tr)
  • Syntheses, characterizations, thermal and photophysical properties of cyclophosphazenes containing adamantane units. (gtu.edu.tr)
  • First, adamantane derivatives that interfere with the ion channel function of the variant M2 protein of amantadine-resistant viruses may prevent drug resistance, if they are used in mixture with amantadine. (nih.gov)
  • Bromantane, sold under the brand name Ladasten, is an atypical psychostimulant and anxiolytic drug of the adamantane family related to amantadine and memantine which is used in Russia in the treatment of neurasthenia. (wikipedia.org)
  • Nitrogen-containing heterocyclic compounds such as 1,4-thiazine and its benzo derivatives are important compounds in many different research fields due to their remarkable biological properties. (chemenu.com)
  • Although it is frequently labeled as a psychostimulant, bromantane is distinct in its pharmacology and effects relative to typical psychostimulants, such as the phenethylamines (e.g., amphetamine and its derivatives) and their structural analogues (e.g., methylphenidate, cocaine, mesocarb, etc. (wikipedia.org)
  • After some biochemical experimentation, scientists found an adamantane derivative, called aminoadamantane, could fight viruses, apparently by interfering with the proteins germs use to infect cells. (spacedaily.com)
  • Although they learned to synthesize adamantane, fusing even a few such cages together proved extraordinarily difficult, and efforts at creating larger diamondoids failed. (spacedaily.com)
  • The main aim of our original work in this paper is to synthesize new pyridone derivatives for the sake of their biological evaluation [ 7 ]. (tsijournals.com)
  • Synthesis and Antimicrobial Evaluation of New Cephalosporin Derivatives Containing Cyclic Disulfide Moieties. (uzh.ch)
  • In this paper, the in vitro formation of several new diclofenac derivatives, initially resulting from oxidative decarboxylation, similar to what happens in vivo, is revealed. (ua.pt)
  • In this study, we rationally designed and synthesized a series of baicalein derivatives and identified a lead compound, FNDR-10132, that displayed potent in vitro antimalarial activity against Plasmodium falciparum (P. falciparum), both chloroquine-sensitive (60 nM) and chloroquine-resistant (177 nM) parasites. (bvsalud.org)
  • By itself, such a cage has atoms of hydrogen attached to its surface and is known as adamantane, from "adamas," the Greek word for diamond. (spacedaily.com)
  • In this study, we took a rational and iterative approach to develop a series of baicalein derivatives with improved antiviral activity against Dengue virus (DENV). (bvsalud.org)
  • In addition the antimicrobial activity of some selected derivatives was reported. (tsijournals.com)
  • In this paper we present calculations of the static polarizability and its derivatives for the adamantane molecule carried out at the density functional theory level using the B3LYP exchange-correlation functional and Sadlej's polarized valence triple zeta basis set. (epj.org)
  • There are many pyridopyrazine derivatives on the market for the treatment of various pharmacological diseases. (chemenu.com)