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  • IUdR
  • When HeLa cells were grown with 5 µ m 5-iodo-2′-deoxyuridine (IUdR) there was an increase in alkaline phosphatase activity after about 24 hr, reaching a maximum usually at about 72 hr. (aacrjournals.org)
  • dUMP
  • Furthermore, structures of the Leishmania enzyme in the presence of dUMP and deoxyuridine coupled with tryptophan fluorescence quenching indicate that occupation of the phosphate binding region is essential for induction of the closed conformation and hence for substrate binding. (whiterose.ac.uk)
  • Folate is an essential nutrient acting as methyl donor for conversion of deoxyuridine monophosphate (dUMP)to deoxythymidine monophosphate required for DNA synthesis and repair. (thefreedictionary.com)
  • synthesis
  • Also, it has been considered that FudR is converted to 5-fluoro-2'-deoxyuridine-5'-monophosphate (commonly called FduMP) in cells, and this inhibits thymidylate synthetase and consequently inhibits DNA synthesis, whereby a carcinostatic activity is exhibited [C. Heidelberger et al. (google.com)
  • cells
  • In this report we describe results of experiments testing the efficacy of 5-[125I]-iodo-2'-deoxyuridine (125IdU) for purging murine RAW117 large cell lymphoma cells (Joshi et al. (curehunter.com)
  • Although AID has been shown to deaminate deoxycytidine to deoxyuridine in DNA in vitro, there is no physical evidence for increased uracils in DNA from cells expressing AID in vivo. (semanticscholar.org)