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1566090377 2075 0 0 36 8784504 125 1 2 2 0 0 589788 145123653665928 18138674097865049224 0 1 590004 236233457971233 1802239034359590945 0 92000.000000 1 deoxyribonuclease (DNase, for short) is an enzyme that catalyzes the hydrolytic cleavage of phosphodiester linkages in the DNA backbone, thus degrading DNA.]]> deoxyribonuclease (DNase, for short) is an enzyme that catalyzes the hydrolytic cleavage of phosphodiester linkages in the DNA backbone, thus degrading DNA.]]> DNase found in metazoans are known as deoxyribonuclease I and deoxyribonuclease II.]]> Deoxyribonuclease II ( EC 3.1.22.1 , DNase II , pancreatic DNase II , deoxyribonucleate 3'-nucleotidohydrolase , pancreatic DNase II , acid deoxyribonuclease , acid DNase ) hydrolyzes deoxyribonucleotide linkages in native and denatured DNA , yielding products with 3'-phosphates.]]> 92000.000000 1 Deoxyribonucleases are one type of nuclease, a generic term for enzymes capable of hydrolyzing phosphodiester bonds that link nucleotides.]]> Deoxyribonucleases are one type of nuclease, a generic term for enzymes capable of hydrolyzing phosphodiester bonds that link nucleotides.]]> 48000.000000 1 28000.000000 47 enzyme catalyses the following chemical reaction Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products Deoxyribonuclease IV is a type of deoxyribonuclease that functions at AP-sites.]]> enzyme catalyses the following chemical reaction Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products Deoxyribonuclease IV is a type of deoxyribonuclease that functions at AP-sites.]]> form of the enzyme deoxyribonuclease, are given to thin mucus, facilitating its clearance from the lungs through coughing.]]> 28000.000000 8 28000.000000 1 7000.000000 109 2800.000000 1128 1800.000000 793 1600.000000 4966 1500.000000 2063 1300.000000 2751 700.000000 2444 400.000000 335 deoxyribonucleases are known, which differ in their substrate specificities, chemical mechanisms, and biological functions.]]> deoxyribonucleases are known, which differ in their substrate specificities, chemical mechanisms, and biological functions.]]> <![CDATA[Deoxyribonuclease - Wikipedia]]> 0 4485 176911348600 253344.984375 1518162247 1518162247 2473214769 en 1566090378 242 0 0 36 8784504 2318 1 2 2 0 0 589788 145123653665928 18138674097865049224 0 1 590004 236233457971233 1802239034359590945 0 160000.000000 1 deoxyribonuclease (DNase, for short) is an enzyme that catalyzes the hydrolytic cleavage of phosphodiester linkages in the DNA backbone, thus degrading DNA.]]> deoxyribonuclease (DNase, for short) is an enzyme that catalyzes the hydrolytic cleavage of phosphodiester linkages in the DNA backbone, thus degrading DNA.]]> DNase found in metazoans are known as deoxyribonuclease I and deoxyribonuclease II.]]> Deoxyribonuclease II ( EC 3.1.22.1 , DNase II , pancreatic DNase II , deoxyribonucleate 3'-nucleotidohydrolase , pancreatic DNase II , acid deoxyribonuclease , acid DNase ) hydrolyzes deoxyribonucleotide linkages in native and denatured DNA , yielding products with 3'-phosphates.]]> Deoxyribonuclease I (DNase I) ( EC:3.1.21.1 ) [ PMID: 3713845 ] is a vertebrate enzyme which catalyzes the endonucleolytic cleavage of double-stranded DNA to 5'- phosphodinucleotide and 5'-phosphooligonucleotide end-products.]]> Deoxyribonuclease I like 1 RNAi, DNASE1L1 RNAi, deoxyribonuclease I-like 1muscle-specific RNAi, DNase I-like 1 RNAi, DNase X RNAi, DNASEX RNAi, DNL1LEC 3.1.21.]]> Deoxyribonuclease (pronounced 'dee-oxy-rybo-noo-clee-ase'), or recombinant human deoxyribonuclease 1 (rhDNase or DNase), is an experimental drug used to treat cystic fibrosis (CF), an inherited lung disease.]]> intrapleural tissue plasminogen activator (tPA) and human recombinant deoxyribonuclease (DNase) twice daily for a total of 6 doses has been shown to decrease surgical referral and improve radiographic imaging.]]> deoxyribonuclease I (DNase I) on the early phase of blood-borne lung metastasis in rats were studied using confocal laser scanning microscopy and AH-109A cells labeled either with carboxyfluorescein diacetate succinimyl ester or with 51Cr.]]> deoxyribonuclease and/or ciprofloxacin (DNase, Cipro, and DNase/Cipro powders) were produced by spray-drying with dipalmitylphosphatidylcholine, albumin, and lactose as excipients, and their antibacterial effects were evaluated using the artificial sputum model.]]> 94000.000000 12 112000.000000 8 100000.000000 1 Deoxyribonucleases are one type of nuclease, a generic term for enzymes capable of hydrolyzing phosphodiester bonds that link nucleotides.]]> Deoxyribonucleases are one type of nuclease, a generic term for enzymes capable of hydrolyzing phosphodiester bonds that link nucleotides.]]> deoxyribonuclease subunit B (ATP-dependent helicase/nuclease AddB).]]> 70000.000000 24 46000.000000 216 protein resource accession number Q8WZ79 for "DNASE2B - Deoxyribonuclease-2-beta precursor - Homo sapiens (Human) - DNASE2B gene & protein" at UniProt .]]> protein resource accession number Q8WZ79 for "DNASE2B - Deoxyribonuclease-2-beta precursor - Homo sapiens (Human) - DNASE2B gene & protein" at UniProt .]]> gene for human deoxyribonuclease, which chops up the protein but does not cause allergic reactions.]]> 80000.000000 1 80000.000000 1 80000.000000 1 45000.000000 214 72000.000000 1 72000.000000 16 48000.000000 1 30000.000000 11 Intrapleural tissue plasminogen activator (tPA) combined with deoxyribonuclease has been shown to increase pleural drainage, decrease hospital length of stay, and decrease need for surgery in parapneumonic effusions and empyema.]]> Intrapleural tissue plasminogen activator (tPA) combined with deoxyribonuclease has been shown to increase pleural drainage, decrease hospital length of stay, and decrease need for surgery in parapneumonic effusions and empyema.]]> 40000.000000 41 34000.000000 47 enzyme catalyses the following chemical reaction Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products Deoxyribonuclease IV is a type of deoxyribonuclease that functions at AP-sites.]]> enzyme catalyses the following chemical reaction Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products Deoxyribonuclease IV is a type of deoxyribonuclease that functions at AP-sites.]]> Deoxyribonuclease I Enzyme is an enzyme.]]> 64000.000000 1 56000.000000 15 36000.000000 1 48000.000000 15 19000.000000 195 47000.000000 6 40000.000000 1 40000.000000 1 36000.000000 22 22000.000000 297 acid uptake and deoxyribonuclease action external to cells in the genetic transformation of Diplococcus pneumoniae .]]> acid uptake and deoxyribonuclease action external to cells in the genetic transformation of Diplococcus pneumoniae .]]> acid deoxyribonuclease on T5 bacteriophage DNA results in a "random distribution" of sizes of duplex fragments as judged by electron microscopy.]]> 16000.000000 7 28000.000000 1 28000.000000 1 28000.000000 8 28000.000000 1 15000.000000 183 5500.000000 10802 16000.000000 1 16000.000000 1 16000.000000 1 3800.000000 768 Deoxyribonuclease I like 1 RNAi can be used in a variety of model species: Human.]]> Deoxyribonuclease I like 1 RNAi can be used in a variety of model species: Human.]]> 9000.000000 145 3100.000000 5286 deoxyribonuclease products.]]> deoxyribonuclease products.]]> 3500.000000 7974 10000.000000 56 10000.000000 200 8200.000000 490 3200.000000 533 7000.000000 109 2800.000000 1128 2000.000000 4966 4000.000000 122 2600.000000 815 2400.000000 2008 1600.000000 4503 2100.000000 8800 2100.000000 1257 Deoxyribonuclease I like 1 RNAi for use in common research applications.]]> Deoxyribonuclease I like 1 RNAi for use in common research applications.]]> 1500.000000 2082 1400.000000 5018 1800.000000 707 900.000000 5018 2500.000000 317 deoxyribonuclease is sometimes included in cell isolation procedures to digest the nucleic acids without damaging the intact cells.]]> deoxyribonuclease is sometimes included in cell isolation procedures to digest the nucleic acids without damaging the intact cells.]]> 1500.000000 6715 1500.000000 1401 deoxyribonucleases are known, which differ in their substrate specificities, chemical mechanisms, and biological functions.]]> deoxyribonucleases are known, which differ in their substrate specificities, chemical mechanisms, and biological functions.]]> 1500.000000 1740 1800.000000 3668 1600.000000 744 1600.000000 525 900.000000 8605 900.000000 5147 900.000000 492 1300.000000 8996 1300.000000 10384 1200.000000 3033 1200.000000 1795 1000.000000 894 1000.000000 329 1000.000000 6708 600.000000 6735 700.000000 3206 700.000000 3426 700.000000 2222 400.000000 1934 400.000000 335 <![CDATA[Deoxyribonuclease - Wikipedia]]> 0 4485 176911348600 253344.984375 1518162247 1518162247 2473214769 en