Deoxy. Medical search. Frequent questions

Synthesis of 1-deoxy-1-[(4-quinazolon-3-yl) amino/methyl-amino-d-fructose as cns active compounds. (ijpsonline.com)

2-Deoxy-D-glucose (2DG) has recently received emergency approval for the treatment of COVID-19 in India, after a successful clinical trial. (nature.com)
Tracer techniques and quantitative autoradiographic and tissue counting models for measurement of metabolic rates were combined with positron computed tomography (PCT) and (F-18)2-fluoro-2-deoxy-D-glucose (FDG) for the measurement of local cerebral metabolic rate for glucose (LCMRGlc) in humans. (nih.gov)
A new series of 4-quinazolone i.e. 1-deoxy-1-(alpha-substituted-3-amino/methylamino-4-quinazolono)-D-fruc tose have been synthesized by refluxing oxalate salt of 3-amino-4-quinazolone and anhydrous D-glucose, with a view to observe the effect of aldose and amines linkage on central nervous system. (ijpsonline.com)
Objective To evaluate the efficacy and safety of 2-deoxy-D-glucose (2-DG) in the treatment of COVID-19. (medrxiv.org)
The mylohyoid muscle is often believed to exhibit high physiologic fluoro-deoxy-glucose (FDG) uptake. (uzh.ch)
Schooling mediates brain reserve in Alzheimer's disease: findings of fluoro-deoxy-glucose-positron emission tomography. (bvsalud.org)

Deoxyribose is derived from the same precursor as ribose being that the reduction of the sugar with the extra hydroxyl group results in the deoxy-sugar, which has its hydroxyl group replaced with a hydrogen atom. (wikipedia.org)
What is meant by the syllable deoxy in deoxyribose? (tourwimberleytx.com)

Deoxy sugars are sugars that have had a hydroxyl group replaced with a hydrogen atom. (wikipedia.org)
containing less oxygen in the molecule than the compound from which it is derived deoxy sugars -usually used in combination deoxyribonucleic acid. (tourwimberleytx.com)

deoxy-BIGCHAP is a non-ionic detergent possessing deoxycholic acid and a gluconamide polar group. (dojindo.com)
The deoxy prefix indicates that the 2′ carbon atom of the sugar lacks the oxygen atom that is linked to the 2′ carbon atom of ribose (the sugar in ribonucleic acid, or RNA), as shown in Figure 5.2. (tourwimberleytx.com)

Uridine phosphorylase (UPase) catalyzes the reversible conversion of uridine into uracil and contributes to the antineoplastic activity of 5′-deoxy-5-fluorouridine (5′-DFUR) and homeostasis of uridine levels in plasma and tissues. (aspetjournals.org)
Cytosolic thymidine phosphorylase (TYMP) catalyzes the reversible reactions of thymine or uracil with 2-deoxy-D-ribose 1-phosphate to form thymidine or deoxyuridine and orthiophosphate. (reactome.org)

article{663446, abstract = {{During ramp exercise the deoxy[Hb + Mb] pattern follows a sigmoid model [f(x) = f(0) + A/(1 + exp(-(-c + dx)))], indicating a non-linear muscle blood flow ((Q) over dotm/oxygen uptake ((V) over dotO(2m))-relationship. (ugent.be)

This work describes a new synthetic route leading to 2′-deoxy-2′-fluorotetradialdose D-nucleoside phosphonates. (cas.cz)

The crystal structure of a complex containing deoxy CpG and a terpyridine platinum compound (TPH) shows a DNA double helical fragment with TPH intercalated between two Watson-Crick GC base pairs. (tmu.edu.tw)

The sugar in DNA has 5 carbon atoms (labelled 1′ - 5′), and is called deoxy-ribose (hence the "Deoxy-ribo" in DNA). (tourwimberleytx.com)

It also can be called as 2-Deoxy-D-erythropentose and the IUPAC name about this chemical is 3,4,5-trihydroxypentanal. (lookchem.com)

The term "deoxy" refers to the fact that there is no oxygen attached to the 2′ carbon atom . (tourwimberleytx.com)

Deoxy[Hb + Mb] was measured at the M. Vastus Lateralis by NIRS, normalized to the total amplitude of the response and expressed as a function of absolute and relative (% peakP) work rate. (ugent.be)
The work rate corresponding to c/d (i.e. 50% of the amplitude of the deoxy[Hb + Mb] response) was the only parameter of the sigmoid that differed significantly between cyclists (57.9 +/- 4.4% and 60.1 +/- 4.1% peakP in the relative and ramp25, respectively) and PAstudents (49.6 +/- 4.2% and 48.2 +/- 5.1% peakP, respectively), indicating a rightward shift of the sigmoid in the cyclists. (ugent.be)
3′-Deoxy-3′-[ 18 F]fluorothymidine positron emission tomography ([ 18 F]FLT-PET) and diffusion-weighted MRI (DW-MRI) are promising approaches to monitor tumor therapy response. (aacrjournals.org)
Oxidative stress biomarkers, such as 8-hydroxy-deoxy-guanosine, genotoxicity biomarkers, and inflammatory response indicators may also be useful, although not specific, as biomarkers of nanomaterial early adverse health effects. (cdc.gov)

We then reduced the levels of galectin-3 expression using siRNA or pharmacologically targeting galectin-3 activity using bis-(3-deoxy-3-(3-fluorophenyl-1H-1,2,3-triazol-1-yl)-β-D-galactopyranosyl)-sulfane. (lu.se)