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  • Inflammation
  • If the dental pulp is exposed, as long as the infection and inflammation can be controlled, conservative therapies can promote the formation of new tertiary dentine in a stem cell-led reparative process. (frontiersin.org)
  • Inflammation of the dental pulp (pulpitis) generally presents with severe pain as toothache, which is commonly treated by either extracting the tooth or root canal treatment (RCT). (frontiersin.org)
  • The regulatory effect of eugenol on the expression of inflammation and apoptotic genes was evaluated in dental pulp fibroblasts from extracted third molars, cultured under concentration of eugenol of 13 μ M. Eugenol allowed the expression of inflammatory and apoptotic genes when compared with positive and negative controls. (hindawi.com)
  • hDPSC
  • To evaluate both the drug-release profile and the effects on human dental pulp stem cells' (hDPSC) proliferation and viability of novel bi-mix antibiotic-containing scaffolds intended for use as a drug delivery system for root canal disinfection prior to regenerative endodontics. (ovid.com)
  • macrophages
  • The normal dental pulp (Paper III) presented with blood vessels, macrophages and T- lymphocytes positive for the same VEGFs and VEGFRs. (uib.no)
  • clinical
  • Within this anatomical context, our study aimed to evaluate the correlation between dental pulp lesions and clinical diagnosis. (hindawi.com)
  • Under this cooperation, the BGI Clinical will be responsible for the preservation of the collected dental pulp stem cells from patients with such needs from the clinics of the Company. (thefreedictionary.com)
  • however, currently available dental-materials are limited by non-specific action, cytotoxicity and poor clinical handling. (frontiersin.org)
  • periapical
  • However, the picture of VEGF family and their receptors with respect to location and function in the dental pulp and in periapical pathology have so far been incomplete. (uib.no)
  • The aims of this thesis were to identify and map the presence of VEGF family and their receptors VEGFR-2 and -3 in apical periodontitis and dental pulp and to investigate their role in periapical disease development. (uib.no)
  • induce
  • The potential therapeutic application of epigenetic modifying agents, DNA-methyltransferase-inhibitors (DNMTi) and histone-deacetylase-inhibitors (HDACi), have been shown to promote mineralisation and repair processes in dental-pulp-cell (DPC) populations as well as induce the release of bioactive dentine-matrix-components. (frontiersin.org)
  • chamber
  • Focusing on the pulp chamber and in the root canal, we compare the images generated with the OCT technique to the histology. (spie.org)
  • Novel
  • Concerns over the cost and destructive nature of dental treatment have led to the call for novel minimally invasive, biologically based restorative solutions. (frontiersin.org)
  • cells
  • However, the detection limit was lower (10 2 -10 3 cells) when H. pylori bacterial DNA was detected from inflamed pulp specimens. (springer.com)
  • The detection limit of the nested PCR system was 1-10 cells using both H. pylori genomic DNA and bacterial DNA isolated from inflamed pulp specimens. (springer.com)
  • A study in the May 1 issue of the European Journal of Neuroscience shows dental pulp cells provide great support for nerve cells lost in Parkinson s disease and could be transplanted directly into the affected parts of the brain. (innovations-report.com)
  • This is not the first test of stem cells as a therapy for Parkinson s disease-type illnesses, known as neurodegenerative diseases, but Nosrat noted that it is the first to use post-natal stem cells grown from more readily available tooth pulp in the nervous system. (innovations-report.com)
  • Nosrat also has studied dental pulp stem cells as a treatment for spinal cord injuries and said applying that knowledge to treatment of neurodegenerative disease was the next logical step. (innovations-report.com)
  • Nosrat believes cells drawn from dental pulp are more robust because they also produce the neurotrophic factors, which promote nerve cell survival. (innovations-report.com)
  • root canal
  • A root canal ranks high on most people's list of dreaded dental procedures. (news-medical.net)
  • A new chemical solution jointly developed by the University of Adelaide's Dental School and Australian company Dentalife could radically reduce the chance of infection associated with root canal work. (news-medical.net)
  • For patients with toothache, this has resulted in a shift from invasive root-canal-treatment (RCT) toward more conservative vital-pulp-treatment (VPT) procedures, aimed to protect the pulp and harness its natural regenerative capacity. (frontiersin.org)
  • MSCs
  • Therefore, MSCs of dental origin have been tested as candidates for cellular therapy of stomatognathic disorders, such as periodontal disease (PD), and for maxillofacial reconstruction. (hindawi.com)