Dental caries dental plaque is biofilm biofilms. Medical search. Frequent questions

Bacteria of dental caries in primary and permanent teeth in children and young adults. (nature.com)
Brackets and orthodontic appliances enhance plaque accumulation and increase the count of oral bacteria during the course of orthodontic treatment. (thejcdp.com)
Dental plaques are biofilms that cause dental caries by demineralization with acidogenic bacteria. (illinois.edu)
Using plants to produce antimicrobial peptides, the researchers were able to rapidly kill tooth-decay-causing bacteria and thwart their ability to form biofilms on a tooth-like surface with a single topical treatment. (upenn.edu)
The peptides were even more effective when combined with an enzyme that degrades the matrix, which surrounds and protects bacteria residing inside biofilms. (upenn.edu)
Bringing our research together led to this new concept of a topical protein drug made in plants that can both kill bacteria and break down the oral biofilm. (upenn.edu)
In the past, researchers have identified antimicrobial peptides that are potent killers of caries-causing bacteria. (upenn.edu)
But these agents are expensive to make and have had limited success at killing bacteria protected by the extracellular matrix, as is found in dental plaque. (upenn.edu)
These carbohydrates act as nutrients for biofilm bacteria, especially acidogenic and aciduric species. (bvsalud.org)
Through this nanohybrid system, we would like to introduce a concept of exploiting the natural settings found in pathological conditions (high sugar and acidic pH) to trigger self-generating chemical weapons used by commensals to fight against pathogenic bacteria to deter cariogenic biofilm establishment," says Dr. Liu. (upenn.edu)
Plaque is a biofilm, which is made of many layers of hundreds of different types of bacteria (germs). (listerine.ca)
These bacteria stick to the surfaces of your teeth resulting in a substance called dental plaque or dental biofilm. (listerine.ca)
The bacteria in plaque are constantly reproducing. (listerine.ca)
Our saliva can allow bacteria to stick to the surface of our teeth forming plaque. (listerine.ca)
When we eat, the bacteria in plaque use the food as energy and grow and multiply. (listerine.ca)
Brush twice daily to remove food particles that feed the bacteria that cause plaque. (listerine.ca)
Bacteria survive in various environments by forming biofilms. (biomedcentral.com)
In this study, we evaluated the ability of two types of biosurfactants (rhamnolipids and surfactin) to inhibit growth and biofilm formation ability of oral pathogenic bacteria such as Aggregatibacter actinomycetemcomitans , Streptococcus mutans , and Streptococcus sanguinis . (biomedcentral.com)
Rhamnolipids inhibited the growth and biofilm formation ability of all examined oral bacteria. (biomedcentral.com)
Streptococcus mutans , a representative bacteria of tooth decay [ 10 ], forms plaques (biofilm) on tooth surfaces and produces lactate from sugars such as sucrose, which demineralizes teeth and causes dental caries. (biomedcentral.com)
Therefore, removal of biofilms formed by periodontopathogenic bacteria prevents a variety of diseases. (biomedcentral.com)
Anti-bacterial agents and disinfectants are effective against planktonic bacteria (bacteria suspended in liquid), however, they are not effective against biofilm-forming bacteria due to the difficulty of chemicals penetrating the biofilm. (biomedcentral.com)
I would like to dispel the mistaken belief that drilling out a carious lesion and placing a restoration will eliminate the bacteria and thereby stop caries progression. (positivehealth.com)
Cariogenic bacteria are found in the complex biofilm which contains many kinds of bacteria called dental plaque. (positivehealth.com)
Bacteria within biofilms are enmeshed in an exopolysaccharides (EPS)-rich matrix. (rochester.edu)
Furthermore, EPS-embedded bacteria also create highly protected and acidic microenvironments that promote cariogenic biofilm build-up and acid-dissolution of tooth enamel. (rochester.edu)
Recently researchers from the University of Pennsylvania School of Dental Medicine discovered that, in many cases, early childhood caries result from dental plaque that contains both bacteria and fungus working together to make the biofilm on the teeth more pathogenic and difficult to remove. (mymedtale.com)
During the last several years, researchers have observed that the dental plaque in children with early childhood caries often contained Candida albicans , a fungal species that normally colonizes mucosal surfaces, in addition to Streptococcus mutans, the bacteria generally associated with tooth decay. (mymedtale.com)
Work in Koo's lab demonstrated that an enzyme produced by the bacteria, termed GtfB, can bind to Candida and when sugar is present (a dietary hallmark in childhood caries) a sticky polymeric matrix forms on its cell surface, enabling the fungus to bind to teeth and associate with bacterial counterparts. (mymedtale.com)
To understand why the combination approach was so effective against C. albicans even without killing many more bacteria, the researchers looked closely at high-resolution microscopic images of the biofilms with the various treatment combinations. (mymedtale.com)
When considering the role of supragingival dental plaque in caries, the proportion of acid producing bacteria (particularly S. mutans ), has direct relevance to the pathogenicity of the plaque. (biomedcentral.com)

Streptococcus mutans are responsible for the production of dextran which serves to stick the plaque on the teeth. (healthnews.com)
Streptococcus mutans ( S. mutans ) is among the most commonly isolated microorganisms from the cariogenic plaques accumulated on tooth surfaces. (thejcdp.com)
Streptococcus sanguinis ( S. sanguinis ) is another microorganism found in noncariogenic plaques at a pH of 5.5 and its presence in dental plaque indicates low cariogenic activity of plaque. (thejcdp.com)
It precisely kills the cariogenic pathogen Streptococcus mutans and degrades the extracellular matrix while sparing commensals such as Streptococcus oralis in a low-pH environment, resulting in localized biofilm disruption," says Dr. Liu. (upenn.edu)
Streptococcus mutans has been clearly implicated in dental caries. (drtbalu.co)
Streptococcus sanguinis is another plaque-forming strain that has been reported to cause infective endocarditis by forming biofilms on the endocardium and heart valves [ 11 ]. (biomedcentral.com)
On the one hand, the ability of green tea polyphenols to inhibit Streptococcus mutans growth, biofilm formation, and acid production may contribute to its beneficial effects for dental caries [ 9 - 11 ]. (biomedcentral.com)
Streptococcus mutans is associated with pathogenesis of oral cavity, gingivoperiodontal diseases and bacteremia following dental manipulations. (biomedcentral.com)

Severe early childhood caries, which does not typically resolve with operative treatment. (wikipedia.org)
secondary caries, early childhood caries, and root caries. (researchgate.net)
Early childhood caries, a form of severe tooth decay affecting toddlers and preschoolers, can set children up for a lifetime of dental and health problems. (mymedtale.com)
The current antimicrobial modalities for treating early childhood caries have limited efficacy," says Hyun (Michel) Koo, a professor in the Department of Orthodontics and divisions of Pediatric Dentistry & Community Oral Health in Penn's School of Dental Medicine. (mymedtale.com)

Among her recent areas of study was a new bi-functional nanotechnology combining natural enzymes with catalytic nanoparticles (termed nanohybrid) that can precisely disrupt cariogenic biofilms and prevent caries onset. (upenn.edu)
Abstract: The development of novel chemotherapeutic approaches against cariogenic biofilms is challenging. (rochester.edu)
Aim 3 will evaluate the efficacy of the developed CT-NPC in disrupting cariogenic biofilms and reducing dental caries in vivo using a rodent model of dental caries under clinically-relevant topical treatment regimen. (rochester.edu)
These glucans are important components of the matrix of cariogenic biofilms. (biomedcentral.com)

summarized how the constituents in SDF each have a role in the arrest of microbial species that cause dental caries. (wikipedia.org)

Aggregatibacter actinomycetemcomitans has been strongly associated with localized aggressive periodontitis via its ability to form biofilms in the subgingival cavity [ 12 ]. (biomedcentral.com)

Lactobacillus acidophilus ( L. acidophilus ) is another microorganism present in cariogenic plaques, which enhances the demineralization of the tooth structure. (thejcdp.com)
Dental caries results from surface demineralization caused by an organized biofilm exposed to fermentable carbohydrates from the diet [1]. (bvsalud.org)
The eventual outcome of dental caries is determined by the dynamic balance between pathological factors that lead to demineralization and protective factors that lead to remineralization. (researchgate.net)
Dental caries covers the continuum from the first atomic level of demineralization, through the initial enamel or root lesion, through dentinal involvement, to eventual cavitation. (researchgate.net)
The caries process can be visualized as a balance between the pathological factors promoting loss of calcium and phosphate from the dental hard tissues (demineralization), and protective factors promoting the process whereby calcium and phosphate enter the dental hard tissues (remineralization). (positivehealth.com)
If the pathological factors tip the balance in favour of more demineralization than remineralization, then there will be caries progression. (positivehealth.com)

Silver diammine fluoride (SDF), also known as silver diamine fluoride in most of the dental literature, (although this is a chemical misnomer) is a topical medication used to treat and prevent dental caries (tooth decay) and relieve dentinal hypersensitivity. (wikipedia.org)
Using orthodontic composite containing nonoparticles with antibacterial activity may prevent dental caries. (thejcdp.com)

Silver and fluoride ions possess antimicrobial properties and are used in the remineralization of enamel and dentin on teeth for preventing and arresting dental caries. (wikipedia.org)
Dental cavities are defined as permanently damaged areas that occur on the hard surfaces of teeth. (healthnews.com)
Preventing the occurrence of plaque on the teeth can reduce the risk of cavities. (healthnews.com)
These sealants form a mechanical barrier on the teeth which ensures that biofilms do not develop over teeth. (healthnews.com)
Here, we show that calcified dental plaque (dental calculus) on ancient teeth preserves a detailed genetic record throughout this period. (nature.com)
The evolution of infections from teeth occurs as follows: Dental diseases gives rise to pulpitis which could progress to periapical abscess which could ultimately spread through bone and soft tissues to involve deeper structures. (drtbalu.co)
You may not always see the plaque on your teeth. (listerine.ca)
The most common way to notice plaque is when you feel a fuzzy or grimy buildup of plaque on your teeth. (listerine.ca)
When you allow the buildup of plaque on teeth you can develop a gum disease known as gingivitis . (listerine.ca)
Clinically, plaque will begin to show up on your teeth within 24 hours of removal. (listerine.ca)
Prevent plaque buildup by brushing your teeth twice daily with a fluoride toothpaste and flossing once each day. (listerine.ca)
Clean between your teeth with dental floss or another interdental cleaner, as recommended by your dentist or hygienist to get rid of plaque and food debris between your teeth. (listerine.ca)
The treatment that these specialized dentists can provide includes not only managing any pathology associated with the dental hard and soft tissues, such as tooth decay and trauma to teeth and lips, but also to manage their patient's psychological needs. (positivehealth.com)
There are several advantages that dentists have when working with children, depending upon the age of the child: there are two sets of teeth, children are still growing, and true primary prevention can be implemented before any dental diseases start. (positivehealth.com)
Saliva and its components are essential for the maintenance of oral health through the formation of the biofilm that covers the teeth and oral mucosa. (positivehealth.com)
The biofilm of the dental plaque is a multispecific microbial consortium, which periodically develops on mammalian teeth, and it can be partially removed through mechanical forces by individual brushing or in specialized oral care medical facilities. (amgtranscend.org)
However milk can be cariogenic if it remains in contact with the teeth for some time, as seen in infants when they sleep with their milk bottles, known as nursing bottle caries. (stackexchange.com)

To evaluate in vitro the effect of a red propolis ethanolic extract (RPE) in the prevention of growth of a cariogenic biofilm and its cytotoxic potential. (bvsalud.org)
Moreover, the impact of such cold plasma on the development of microbial biofilms under various relevant conditions will be established by in vitro studies. (amgtranscend.org)
Then, Aim 2 will evaluate the efficacy of optimized NPCs containing Myr and Far with fluoride (CT-NPC) using our in vitro cariogenic biofilm model. (rochester.edu)

2 Despite the fact that oral hygiene measures are the first line of caries prevention, their efficacy highly depends on patient cooperation. (thejcdp.com)
With this in mind, one possible strategy for caries prevention may be the addition of antimicrobial agents to orthodontic adhesives. (thejcdp.com)
Featherstone JD: The science and practice of caries prevention. (karger.com)
Inhibition of microbial attachment and biofilm formation, as well as methods to strengthen dental enamel to microbial attack represent the key factors in caries prevention. (amgtranscend.org)
The obtained cold plasma with dual effect exhibited through biofilm modulation and enamel strengthen through fluoridation is intended for dental application such as the prevention and therapy of dental caries and enamel deterioration. (amgtranscend.org)
CT-NPC will be also compared to 'gold standards' of caries prevention (fluoride) and antimicrobial therapy (chlorhexidine). (rochester.edu)
Hence, the factors influencing expression of gtf genes are very important for prevention of dental plaques, caries, gingivitis, gingival abscess and even bacteremia following dental manipulation. (biomedcentral.com)

Bacteriologically dental caries and periodontitis differ. (drtbalu.co)
Rhamnolipids inhibit oral bacterial growth and biofilm formation by A. actinomycetemcomitans Y4, and may serve as novel oral drug against localized invasive periodontitis. (biomedcentral.com)
This has led to dental studies that focus on reducing caries incidence, improving the prognosis of periodontitis and decreasing halitosis and candidiasis. (scielo.edu.uy)
generando en la comunidad odontológica estudios con enfoque en: reducción de la incidencia de caries, mejorar el pronóstico de periodontitis y disminución de halitosis y candidiasis. (scielo.edu.uy)
In the last decade, the use of probiotics has generated interest within the dental community with the development of studies focused on reducing caries incidence, improving the prognosis of periodontitis, eliminating halitosis and infections such as oral candidiasis 4 , 7 , 9 . (scielo.edu.uy)
The most frequent oral infections include gingivoperiodontal diseases including gingivitis and periodontitis, are caused by dental plaque, which is a S. mutans produced biofilm[ 9 - 11 ]. (biomedcentral.com)

We propose an antibiotic-free strategy to disrupt the biofilm by engineered clustered carbon dot nanoparticles that function in the acidic environment of the biofilms. (illinois.edu)
Both are able to proliferate and survive in acidic media, resulting in an elevated potential for caries development [3,4]. (bvsalud.org)
Such condition has multiple triggers and is caused mainly by enamel degradation under acidic attack of microbial cells, which compose the biofilm of the dental plaque. (amgtranscend.org)
We will focus on increasing the kinetics of NPC pH-responsive drug release to ensure maximal release of the agents at pH consistent with the acidic biofilm milieu. (rochester.edu)
Thus, we will investigate how CT-NPC disrupts these virulence properties more effectively than CT using novel methods to assess spatiotemporal development of EPS matrix, acidic pH niches and gene expression in situ within intact 3D biofilms. (rochester.edu)

Cellulose membrane disks (13 mm, N=12) were used for biofilm formation (24 h) of S. mutans and L. casei , which were treated (1 min) with 0.4% RPE or 0.12% Chlorhexidine (CHX). (bvsalud.org)
Red propolis extract showed antibacterial activity against the tested strains, exhibited acceptable cytotoxicity and reduced the colonization of S. mutans and L. casei in a biofilm membrane model. (bvsalud.org)

I think this work gives us a glimpse into alternative ways to disrupt cross-kingdom biofilm, a combinatorial approach that considers the fungal and bacterial components. (mymedtale.com)

In order to prevent the clinical appearance of dental caries and to reduce its progression, several products with antimicrobial activity can be used [5,6]. (bvsalud.org)

A total of 180 composite disks were fabricated for eluted component, disk agar diffusion (DAD), and biofilm inhibition tests. (thejcdp.com)
90% biofilm inhibition associated with the contact-mediated interaction of nanoparticles with the bacterial membrane, excessive reactive oxygen species generation, and DNA fragmentation. (illinois.edu)

Figure 1: Phylum-level microbial composition of ancient dental calculus deposits. (nature.com)
Biofilms are three-dimensional structures consisting of various microbial populations attached to a surface by extracellular polymeric substances (EPS) produced by these microorganisms [ 1 ]. (biomedcentral.com)
The purpose of this project is to elaborate a cold plasma based method in order to modulate microbial attachment and biofilm formation and to improve the retention of fluoride in an enamel-like model. (amgtranscend.org)
In this project, we will start with a technology-formulated concept based on a cold plasma treatment (TRL 1-2), and we will end by validating the technology in laboratory conditions, enlightening the plasma ability to improve fluoride retention and modulate microbial biofilm formation in an enamel-like hydroxyapatite based model (TRL 4). (amgtranscend.org)

Plaque is nothing by supragingival biofilm. (drtbalu.co)

Odontogenic infections arise as a result of dental caries (advanced) or from periodontal disease. (drtbalu.co)
Epidemiological and clinical studies have provided some evidence that green tea consumption may have potential oral health benefits thus resulting in a decreased incidence/severity of dental caries and periodontal diseases, the two most common oral infections [ 4 - 8 ]. (biomedcentral.com)

It gradually forms as plaque absorbs minerals from your saliva. (listerine.ca)
SLS had no statistically significant effect on total plaque and total saliva fluoride but significantly increased salivary fluid and plaque fluid fluoride (by 147 and 205%, respectively). (karger.com)
These results suggest that the nonfluoride components of topical agents can be manipulated to improve the fluoride release characteristics from oral fluoride reservoirs and that statistically significant change may be observed in plaque fluid and salivary fluid fluoride concentrations that may not be observed in total plaque and total saliva fluoride concentrations. (karger.com)

The higher the concentration of fluoride in a compound, the more effective its mechanisms in inhibiting bacterial biofilm formation. (wikipedia.org)
Importantly, 16S rRNA analysis of the dental microbiota showed that the diversity and richness of bacterial species did not substantially change with nanoparticle treatment. (illinois.edu)
It can predispose to dental caries due to the presence of bacterial byproducts present within it. (drtbalu.co)
Bacterial biofilms often cause significant problems to medical instruments and industrial processes. (biomedcentral.com)
Thus, there is a requirement for the development of a simpler and more effective oral care capable of inhibiting oral bacterial growth and biofilm formation. (biomedcentral.com)

Apart from dental causes, cavities are also associated with several systemic diseases. (healthnews.com)
Now, a report by University of Pennsylvania School of Dental Medicine scientists in the journal Biomaterials suggests a new approach for delivering a protein drug to treat and prevent oral diseases, including dental caries, commonly known as cavities. (upenn.edu)

Learn how plaque and other factors can lead to gingivitis and more advanced forms of gum disease . (listerine.ca)
It cleans deeper than brushing and flossing alone while fighting tartar buildup and killing up to 99.9% of germs that cause bad breath, plaque, and gingivitis. (listerine.ca)

To treat dental cavities, dentists focus on early detection of lesions, assessing the risk and severity of caries, treating lesions, and maintaining dental health to prevent the recurrence of cavities. (healthnews.com)

Furthermore, topically applied NPC bind avidly to pellicle and EPS, and accumulate within biofilms. (rochester.edu)

Successful completion of these aims will lead to a highly efficacious and clinically-translatable therapy that may be superior to current anti-plaque/anti-caries modalities and will motivate formulation development for clinical studies. (rochester.edu)

Although paediatric dentistry covers all aspects of children's dentistry, in this article I would like to concentrate on one area of the speciality, tooth decay or as it is called clinically, dental caries. (positivehealth.com)

Dental Cavities: Why Do They Happen? (healthnews.com)
But did you wonder why dental cavities happen? (healthnews.com)
What are some of the common ways to manage dental cavities? (healthnews.com)
Cavities are commonly referred to as dental caries or tooth decay. (healthnews.com)
Dental cavities are the most prevalent disease in the US and about 98% adults have dental caries by age 20 years. (healthnews.com)
Therefore, poor oral and dental hygiene behavior, wrong brushing habits and ways, increasing age, and intake of foods and drinks rich in sugar can trigger cavities. (healthnews.com)
Cavities are related to the formation of biofilms caused by fluctuations in the pH of the oral cavity. (healthnews.com)
Dental cavities can be prevented through several effective practices. (healthnews.com)
The main cause of cavities is poor dental and oral hygiene behavior, which can be altered by daily oral care. (healthnews.com)
Recent research mentions the potential for vaccines that can prevent dental cavities. (healthnews.com)

The product was cleared for sale by the U.S. Food and Drug Administration as a Class II medical device for the treatment of dentinal hypersensitivity, and has been classified as an 'effective, efficient, equitable and safe caries-preventative agent' by the Institute of Medicine and the Millennium Goals of the World Health Organization in 2009. (wikipedia.org)

Regarding the effects of green tea polyphenols on the S. moorei colonization properties, it was found that biofilm formation on EGCG-treated surfaces was significantly affected, and that green tea extract and EGCG can cause the eradication of pre-formed S. moorei biofilms. (biomedcentral.com)

The observations were largely in concordance with the biofilm assay results. (biomedcentral.com)

Overall, this study presents a safe and effective approach to decrease the dental biofilm formation without disrupting the ecological balance of the oral cavity. (illinois.edu)
The control group of biofilm formation was not submitted to any treatment. (bvsalud.org)
Plaque formation predisoposes to odontoenic infections. (drtbalu.co)
Techniques to inhibit biofilm formation are essential and have wide applications. (biomedcentral.com)
We also attempted to determine the step in the biofilm formation process that was inhibited by biosurfactants. (biomedcentral.com)
The results clearly demonstrated that rhamnolipids inhibit biofilm formation after the initiation process, however, they do not affect attachment or maturation. (biomedcentral.com)
Therefore, inhibiting the growth of oral pathogens, as well as effectively preventing biofilm formation contribute to reducing these risks. (biomedcentral.com)
Biofilm formation was quantified by crystal violet staining. (biomedcentral.com)

In addition, retention of these agents at tooth-biofilm interface could be enhanced to maximize their efficacy in vivo. (rochester.edu)

We demonstrated that these agents in combination severely compromise EPS-matrix assembly and cariogenic biofilm development, resulting in a highly effective anti-caries therapy in vivo. (rochester.edu)
We completely eradicated the fungal infection, both in the lab-grown biofilms but also those formed in vivo using an animal model," Koo notes, yet this achievement came without enhancing antibacterial activity. (mymedtale.com)

These biofilms are composed of polysaccharides and it provides the microbes protective environment to reside and proliferate. (drtbalu.co)

are the main microorganisms responsible for the onset and progression of caries, respectively [2]. (bvsalud.org)

These plaques contain mainly gram negative anaerobic organism. (drtbalu.co)

The funding will enable further development of the approach, including coencapsulation and delivery of synergistic anti-biofilm drugs and testing the effectiveness of the approach in rodent models. (rochester.edu)
Realizing this, Koo, Kim, and colleagues wanted to see whether a two-pronged approach might break apart the synergistic association and effectively treat the biofilm. (mymedtale.com)

Dental caries predominantly affect children and adults of lower socioeconomic status and are responsible for more than $40 billion in health-care spending annually. (upenn.edu)
Despite the technological progress of the last decade, dental caries is still the most frequent oral health threat in children and adults alike. (amgtranscend.org)

And Daniell learned that Koo had done extensive work on caries-causing biofilms, including searching for alternative approaches to degrade them or prevent them altogether. (upenn.edu)
Through her research, as part of the research lab of Dr. Michel Koo in the Department of Orthodontics and Divisions of Community Oral Health and Pediatric Dentistry, Dr. Liu is working to understand caries etiopathology and develop novel anti-caries approaches. (upenn.edu)

Although sodium lauryl sulfate (SLS) is a common dentifrice ingredient, the influence of this ion on plaque fluid and salivary fluid fluoride has not been examined. (karger.com)
The purpose of this study was to investigate the effect of SLS on these parameters and to examine the effect of this ion on total (or whole) plaque fluoride, an important source of plaque fluid fluoride after a sufficient interval following fluoride administration, and on total salivary fluoride, a parameter often used as a surrogate measure of salivary fluid fluoride. (karger.com)

To overcome these remarkable challenges, our previous NIH supported (DE018023) studies developed a potent anti-caries approach by combining food-derived antibiofilm agents (myricetin and farnesol) with fluoride. (rochester.edu)

Intervention in the caries process can occur at any stage, either naturally or by the insertion of some procedure or treatment. (researchgate.net)

As scientists we have many opportunities to develop breakthrough treatments but cost is a huge obstacle," said Hyun (Michel) Koo , co-corresponding author on the study and professor in the Department of Orthodontics and divisions of Pediatric Dentistry and Community Oral Health in Penn Dental Medicine. (upenn.edu)
The collaboration of Danielle Benoit, associate professor of biomedical engineering, with Hyun Koo at the University of Pennsylvania School of Dental Medicine, has resulted in a $1,923,792, four-year grant from the National Institutes of Health to further refine their novel approach to fighting dental plaque and tooth decay. (rochester.edu)

Dr. Yuan Liu, a Research Associate in the Division of Restorative Dentistry at Penn Dental Medicine , is the 2021 recipient of the IADR Joseph Lister Award for New Investigators. (upenn.edu)

In the UK, this is classified as 'off-label' use of a topical medicament for arresting caries as it is licensed for treatment of dentine hypersensitivity. (wikipedia.org)

They observed that, in untreated biofilms and those treated with solely fluconazole, the fungus was coated with abundant sticky matrix, which seemed to serve as a protective shield against the antifungal compound. (mymedtale.com)
Several published reviews have concluded that milk is of very low cariogenicity and may have some caries protective potential. (stackexchange.com)

To become a specialist in paediatric dentistry, several years of additional training are required after obtaining a general dental qualification. (positivehealth.com)

This biofilm is formed by the accumulation of microbes in the oral cavity which causes the pH of the mouth to decrease. (healthnews.com)

The platform is low-cost compared to the current means of producing biopharmaceuticals and presents a unique opportunity to develop an affordable therapeutic approach that simultaneously attacks disease-causing plaque and promotes gum health, the researchers said. (upenn.edu)

Anatomy22

Organisms27

Diseases35

Chemicals and Drugs39

Analytical, Diagnostic and Therapeutic Techniques and Equipment65

Psychiatry and Psychology4

Phenomena and Processes16

Disciplines and Occupations11

Anthropology, Education, Sociology and Social Phenomena8

Technology, Industry, Agriculture20

Humanities1

Information Science5

Named Groups8

Health Care50

Geographicals2

Bacteria31

Streptococcus8

Early Childh4

Cariogenic biofilms4

Cause dental caries1

Ability to form biofilms1

Demineralization6

Prevent dental caries2

Teeth17

Vitro3

Prevention7

Periodontitis6

Acidic5

Mutans2

Disrupt1

Antimicrobial1

Inhibition2

Microbial4

Supragingival1

Periodontal2

Saliva3

Bacterial5

Diseases2

Gingivitis2

Severity1

Accumulate1

Modalities1

Clinically1

Cavities10

Dentinal1

Surfaces1

Assay1

Formation8

Efficacy1

Vivo2

Polysaccharides1

Progression1

Gram1

Synergistic2

Adults2

Approaches2

Salivary2

Potent1

Occur1

Hyun2

20211

Topical1

Protective2

Dentistry1

Accumulation1

Researchers1