• The virus is spread mainly by the Aedes aegypti mosquito, which is commonly found throughout the tropical and subtropical Americas. (wikipedia.org)
  • Zika virus is a mosquito-borne flavivirus transmitted primarily by Aedes aegypti mosquitoes. (cdc.gov)
  • Zika virus is transmitted primarily by Aedes aegypti mosquitoes ( 1 , 7 ). (cdc.gov)
  • Aedes albopictus mosquitoes also might transmit the virus. (cdc.gov)
  • Zika virus is primarily spread by the bite of infected Aedes spp. (phila.gov)
  • Zika virus is primarily transmitted by Aedes aegypti mosquitoes, which are found throughout much of the region of the Americas, including parts of the United States ( 2 , 3 ). (cdc.gov)
  • tory testing to the Arbovirus Diagnostic Laboratory at the Over the next 20 years, several ZIKV isolates were Centers for Disease Control and Prevention (CDC, Fort obtained from Aedes spp. (folkhalsomyndigheten.se)
  • Chikungunya Disease Chikungunya disease is transmitted by the Aedes mosquito. (msdmanuals.com)
  • In the Americas, Aedes aegypti is the mosquito vector that is the main source of dengue transmission. (paho.org)
  • It is spread by the yellow fever mosquito ( Aedes aegypti ) and the Asian tiger mosquito ( Aedes albopictus ), which also transmit dengue and chikungunya viruses. (contemporarypediatrics.com)
  • Chikungunya is transmitted by the bite of female mosquitoes of the species Aedes aegypti and A. albopictus . (azolifesciences.com)
  • Cultured Aedes albopictus cells (clone C6/36), persistently infected (PI) with dengue virus type 1 (dengue-1) were found resistant to superinfection with dengue virus type 3 (dengue-3). (microbiologyresearch.org)
  • Semliki Forest virus replication in cultured Aedes albopictus cells: studies on the establishment of persistence. (microbiologyresearch.org)
  • Morphogenesis of Sindbis virus in cultured Aedes albopictus cells. (microbiologyresearch.org)
  • Characteristics of Aedes albopictus cells persistently infected with dengue virus. (microbiologyresearch.org)
  • The virus is transmitted by infected species of Aedes, and Haemagogus mosquitoes. (practo.com)
  • The introduction of the naturally occurring wMel Wolbachia strain into Aedes aegypti mosquitoes has been shown to reduce the ability of the mosquitoes to transmit dengue and other viruses. (mvcac.org)
  • Repelente corporal baseado no Líquido da Casca da castanha de caju - LCC com ação repelente contra o mosquito Aedes aegypti transmissor da Dengue, Febre Chikungunya e Zika Mazzetto, Selma Elaine A fonte original deste documento pode ser restrita, o que pode impedir que leitores externos tenham acesso a ele. (paho.org)
  • Antibody kinetics and real-time reverse transcription PCR results for CHIKV and DENV of 18 chikungunya patients, Brazil, 2016. (cdc.gov)
  • Dengue virus (DENV) suppresses DDC expression at the later stages of infection, during which DENV also inhibits autophagosome-lysosome fusion. (bvsalud.org)
  • Serum levels of dengue virus (DENV) non-structural 1 (NS1) antigen can serve as a valuable prognostic indicator of severe dengue infections. (bvsalud.org)
  • OBJECTIVE: Rare codons were previously shown to be enriched at the beginning of the dengue virus (DENV) open reading frame. (bvsalud.org)
  • Laboratory testing with a rapid conducted at that time showed that 6.1% of the residents assay suggested that a dengue virus (DENV) was the caus- in nearby regions of Uganda had specifi c antibodies to ative agent. (folkhalsomyndigheten.se)
  • Module A contained serum samples spiked with cultured dengue virus (DENV) or chikungunya virus (CHIKV) for the detection of nucleic acid and DENV non-structural protein 1 (NS1) antigen. (who.int)
  • Among 20 laboratories testing Module A, 17 (85%) correctly detected DENV RNA by reverse transcription polymerase chain reaction (RT-PCR), 18 (90%) correctly determined serotype and 19 (95%) correctly identified CHIKV by RT-PCR. (who.int)
  • Global dengue incidence has increased in autochthonous outbreak in over 70 years 4,5 and DENV- recent decades, though the actual numbers of serotype 3 was found to be circulating in the Pacific after dengue cases are masked by underreporting. (who.int)
  • External quality assessment of dengue and chikungunya diagnostics, 2015 co-circulation with DENV. (who.int)
  • The four dengue serotypes (DENV-1, DENV-2, DENV-3 and DENV-4) circulate throughout the Americas, and in some countries simultaneously. (paho.org)
  • Some arboviruses, like dengue (DENV), chikungunya (CHIKV) and Zika (ZIKV), have become fully adapted to urban cycles and no longer require NHPs, forest mosquitoes and a sylvatic cycle for their maintenance [ 7 ]. (biomedcentral.com)
  • Developed by scientists at the New York State Department of Health Wadsworth Center and the University of Texas Medical Branch, the assay outperforms single antigen/antibody ZIKV IgM-Capture ELISA testing in overall sensitivity, specificity, positive predictive value and negative predictive value by detecting IgG-IgA-IgM antibodies to Zika Virus (ZIKV) and Dengue virus (DENV) serotypes 1-4. (healthresearch.org)
  • Since ZIKV, DENV and other flaviviruses including chikungunya, an arbovirus, co-circulate in the same regions, a positive result for one of these viruses does not preclude infection with the others. (healthresearch.org)
  • However, recent evidence suggests that a 4-fold higher titer by PRNT might not discriminate between anti-Zika virus antibodies and cross-reacting antibodies in all persons who have been previously infected with or vaccinated against a related flavivirus. (cdc.gov)
  • With 20 years of experience focused on membrane proteins and antibodies, Integral Molecular's technologies have been integrated into the drug discovery pipelines of over 500 biotech and pharmaceutical companies to help discover new therapies for cancer, diabetes, autoimmune disorders, and viral threats such as SARS-CoV-2, Ebola, Zika, and dengue viruses. (integralmolecular.com)
  • This includes reverse transcription-polymerase chain reaction (RT-PCR) for viral RNA, and immunoglobulin (Ig) M ELISA and plaque reduction neutralization test (PRNT) for Zika virus antibodies. (blogspot.com)
  • When we tested neutralizing antibodies to one virus against the other, we found a low protective response to both. (azolifesciences.com)
  • Although the mice initially infected with Chikungunya had low levels of neutralizing antibodies in their bloodstream, these levels rose rapidly after secondary infection with Mayaro, inducing cross-protection against the latter. (azolifesciences.com)
  • The researchers analyzed neutralization by antibodies but also identified other factors in the mice's immune system that could influence this cross-protection. (azolifesciences.com)
  • Production of memory cells [ B and T lymphocytes ] takes time, but the mice first infected with Chikungunya already had them, so during secondary infection by Mayaro the immune response was faster, including a rise in levels of neutralizing antibodies,' Fumagalli explained. (azolifesciences.com)
  • This experiment served to demonstrate that antibodies produced in response to infection by Chikungunya also led to cross-protection against Mayaro. (azolifesciences.com)
  • In other words, Mayaro and Chikungunya trigger the production of different antibodies, but some of these antibodies are effective against both diseases,' Fumagalli said. (azolifesciences.com)
  • Guidelines for plaque-reduction neutralization testing of human antibodies to dengue viruses. (rjppd.org)
  • 26. Mohammed H, Tomashek KM, Stramer SL, Hunsperger E. Prevalence of anti-dengue immunoglobulin G antibodies among American Red Cross blood donors in Puerto Rico, 2006. (rjppd.org)
  • Monoclonal antibodies specific for dengue virus type 3. (microbiologyresearch.org)
  • An extra step in our assay measures IgG antibodies by avidity testing, which determines the time-frame of infection, whether primary or secondary, and is quick and simple. (healthresearch.org)
  • A specialized blood test, which is exclusively done for the diagnosis of yellow fever, may reveal specific antibodies, which are virus-specific, produced in response to the particular infection. (practo.com)
  • There are several reasons to be worried about, including faster transmission, more severe illness, decreased neutralisation by antibodies and or reduced efficiency of treatment and vaccines.The pandemic is far from over. (metropolisindia.com)
  • The authors found that antibodies from vaccinated individuals were not as effective at neutralizing the virus variant in a lab study. (metropolisindia.com)
  • When a vaccine is administered to an individual, they can make antibodies to many different parts of the virus. (metropolisindia.com)
  • If one part mutates to give rise to a new variant, like the delta variant, then antibodies to other parts of the virus should still provide enough protection. (metropolisindia.com)
  • Book a quantitative COVID antibody test and check how many antibodies you developed after completing your COVID jabs. (metropolisindia.com)
  • Download the latest version of GeneTex's Selected Antibodies for Influenza Virus flyer. (genetex.com)
  • Chunpeng Yang , Rui Gong , Natalia de Val , 2019: Development of Neutralizing Antibodies against Zika Virus Based on Its Envelope Protein Structure, Virologica Sinica, 34, 168-174. (virosin.org)
  • COVID-19 Neutralization Test Key Highlights : Scientists discovered Neutralization antibodies in May 2020 and a possible indicator for treatment and diagnostic target. (jmitra.co.in)
  • The general method of detecting infection with HIV is to observe the presence of antibodies to the virus by an EIA method followed by confirmation with Western Blot. (frenovobio.com)
  • One step HIV Ab Test is a simple, visual qualitative test that detects antibodies in human Whole Blood/serum/plasma. (frenovobio.com)
  • If the specimen contains HIV antibodies, a colored line will appear in the test line region indicating a positive result. (frenovobio.com)
  • TWiV 1045: Less Lassa, CRISPR RNA viruses September 17, 2023 TWiV reviews a Lassa virus mRNA vaccine that confers protection against disease without inducing neutralizing antibodies, and a CRISPR-based method for engineering the genome of RNA viruses. (microbe.tv)
  • Positive and equivocal samples were confirmed for anti-ZIKV-neutralizing antibodies by virus neutralization tests. (ox.ac.uk)
  • Total numbers of patients that seroconverted for Zika virus per assay, antigen, and antibody were as follows: NS1 IgA (n = 8), NS1 IgM (n = 5), envelope IgM (n = 7), NS1 IgG (n = 15), envelope IgG (n = 14) µ-capture IgM (n = 6), and PRNT50 (n = 12). (cdc.gov)
  • However, results of Zika virus antibody testing can be difficult to interpret because of cross-reactivity with related flaviviruses, which can preclude identification of the specific infecting virus, especially when the person previously was infected with or vaccinated against a related flavivirus. (cdc.gov)
  • In these cases, antibody testing can identify additional recent Zika virus infections. (cdc.gov)
  • In these cases, immunoglobulin (Ig) M and neutralizing antibody testing can identify additional recent Zika virus infections ( 6 , 7 ). (cdc.gov)
  • Integral Molecular has developed the Membrane Proteome Array (MPA) platform to de-risk antibody-based therapeutics by testing specificity across the full human membrane proteome expressed in live cells. (integralmolecular.com)
  • As stated by Kuno & Chang [ 15 ], "The three commonly used data for identifying vertebrate reservoirs for arboviruses have been (i) virus isolation from suspected animals, (ii) relatively high antibody prevalence in the animals captured in the field and (iii) demonstration of viraemia (of higher virus titre and duration) in the suspected animals typically obtained under laboratory conditions" [ 15 ]. (biomedcentral.com)
  • Virus and antibody dynamics in acute West Nile virus infection. (rjppd.org)
  • This was determined by indirect immunofluorescent (IF) staining of cultures using monoclonal antibody against a dengue-3 type-specific antigen. (microbiologyresearch.org)
  • Dengue-1 PI cultures stained with this antibody 3 days after superinfection with dengue-3 virus (m.o.i. of 2) had dengue-3 antigen in 0.1 to 1.0% of the cells. (microbiologyresearch.org)
  • An IVI scientist works on an antibody test at IVI headquarters in Seoul, Korea. (ivi.int)
  • IVI tested international standard candidates in terms of binding antibody titer and neutralizing antibody titer, and transferred the results to the United Kingdom's National Institute for Biological Standards and Control. (ivi.int)
  • To date, IVI has completed two samples for binding antibody titer and neutralizing antibody titer and the KDCA has since provided four additional samples which are undergoing testing. (ivi.int)
  • GeneTex is proud to offer an extensive catalog of antibody reagents that can facilitate your research into these and other viruses. (genetex.com)
  • They are working on a technique to manufacture immunity in a test tube by isolating a single antibody for a disease that can be used to specifically target and fight that disease. (justhumanproductions.org)
  • Remember, convalescent plasma or serum, is when you take blood from someone immune to a virus or bacteria, and give their antibody-rich blood to another patient to help them fight off the disease. (justhumanproductions.org)
  • James and his team are working on a technique to manufacture immunity in a test tube… just like Erhlich had dreamed of… and that starts by finding just the right antibody for a disease… like COVID. (justhumanproductions.org)
  • Antibody testing for COVID-19 The COVID-19 pandemic has brought humankind to a stop. (jmitra.co.in)
  • Antithrombin - neutralization set for ATIII (AT-NU10) is a Neutralization Paired Antibody Set for Neutralizing ATIII - 10 determinations. (quadratech.co.uk)
  • Currently available diagnostics: nucleic acid amplification tests (NAAT) and antibody ELISA, have critical problems [1]. (ukri.org)
  • Viraemia during the first week after inoculation has been found in all monkeys tested and antibody has been demonstrated by the 14th day after inoculation. (paho.org)
  • Antibody has also been found in the serum of one of 15 wild monkeys tested. (paho.org)
  • Human IgG antibody Laboratories manufactures the anti jc virus antibody tysabri reagents distributed by Genprice. (essentialbiosafety.info)
  • The Anti Jc Virus Antibody Tysabri reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (essentialbiosafety.info)
  • Description: Quantitativesandwich ELISA kit for measuring Pig Foot and Mouth Disease Virus (FMDV) Antibody (IgG) in samples from serum, plasma, cell culture supernates, tissue homogenates. (essentialbiosafety.info)
  • At YARU, a Dhori virus immune serum of adequate titer has been tested against 31 other tick-borne viruses without any evidence of relationship. (cdc.gov)
  • These RVPs offer researchers a ready-to-use reagent to reliably test vaccinee serum for influenza neutralization, providing an alternative to the standard assay method requiring laborious preparation of live viruses in cells or eggs. (integralmolecular.com)
  • Serum samples were tested for dengue, chikungunya, and nasopharyngeal swabs for respiratory viruses. (cdc.gov)
  • The researchers also analyzed blood serum from patients infected by Chikungunya. (azolifesciences.com)
  • mosquitoes are found throughout much of the Americas, including parts of the United States, and also transmit dengue and chikungunya viruses. (cdc.gov)
  • These mosquitoes can also transmit dengue and chikungunya viruses ( 4 ). (cdc.gov)
  • Overview of Arbovirus, Arenavirus, and Filovirus Infections Arbovirus (arthropod-borne virus) is defined as any virus that is transmitted to humans and/or other vertebrates by certain species of blood-feeding arthropods, mostly insects (flies and mosquitoes). (msdmanuals.com)
  • For dengue, chikungunya, Zika and yellow fever viruses, sylvatic (forest) transmission cycles also exist in some regions and involve non-human primates and forest-dwelling mosquitoes. (biomedcentral.com)
  • Since news of the Zika virus broke, some media outlets were reporting that pesticides used to control mosquitoes in some South American countries-not the virus itself-was responsible for microcephaly, but that theory was recently debunked . (contemporarypediatrics.com)
  • mosquitoes are found throughout much of the Region of the Americas, including parts of the United States, and also transmit dengue and chikungunya viruses ( 4 ). (blogspot.com)
  • Molecular screening of dengue virus in mosquitoes collected from field for early warning signals. (ncdc.gov.in)
  • Included within the series are papers on orbiviruses transmitted by Culicoides, lesser known viruses transmitted by mosquitoes including Cache Valley, Everglades, Jamestown Canyon, and LaCrosse, and recently discovered viruses transmitted by ticks including Bourbon, Heartland, Colorado tick fever, and Powassan. (mvcac.org)
  • Yellow fever virus spreads through the bites of infected mosquitoes. (outbreaknewstoday.com)
  • ZIKV, Zika virus. (cdc.gov)
  • Zika virus (ZIKV) is a mosquito-borne fl avivirus fi rst studies in the absence of epidemics ( 6 - 8 ). (folkhalsomyndigheten.se)
  • Z ported human infections indicated that clinical characteris- ika virus (ZIKV) is a mosquito-transmitted virus in the tics of infection with ZIKV included fever, headache, mal- family Flaviviridae and genus Flavivirus . (folkhalsomyndigheten.se)
  • Since the Zika virus (ZIKV) was first the health ministries of the 22 Members preparedness measures. (who.int)
  • The Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) belonging to the Flavivirus genus and the Flaviviridae family. (rjppd.org)
  • Since the initial outbreak of the disease, it has been recognized that the sensitivities and specificities for current ZIKV testing algorithms have shortcomings. (healthresearch.org)
  • 181B potentially associated with Zika virus (ZIKV) has highlighted the urgent need to identify individuals infected with ZIKV. (who.int)
  • Zika virus (ZIKV), a mosquito-borne transplacentally transmissible flavivirus, is an enveloped virus with an ~10.8 kb plus-strand RNA genome that can cause neurological disease. (mdpi.com)
  • Accurate diagnostics for Zika virus (ZIKV) underpins all public health responses and epidemiology studies of the outbreak. (ukri.org)
  • a) ZIKV PRNT (most specific serological test for ZIKV). (ukri.org)
  • Tests and training will strengthen diagnostic services, and improve management of suspected ZIKV patients. (ukri.org)
  • There is growing evidence that Zika virus (ZIKV) can cause devastating infant brain defects and other neurological disorders in humans. (paho.org)
  • We tested a series of 2′-C- or 2′-O-methyl-substituted nucleosides, 2′-C-fluoro-2′-C-methyl-substituted nucleosides, 3′-O-methyl-substituted nucleosides, 3′-deoxynucleosides, derivatives with 4′-C-azido substitution, heterobase-modified nucleosides, and neplanocins for their ability to inhibit ZIKV replication in cell culture. (paho.org)
  • Antiviral activity was identified when 2′-C-methylated nucleosides were tested, suggesting that these compounds might represent promising lead candidates for further development of specific antivirals against ZIKV. (paho.org)
  • Zika virus (ZIKV) has been presumed to be endemic in Southeast Asia (SEA), with a low rate of human infections. (ox.ac.uk)
  • Zika virus seroprevalence observed in the studied blood donors was low, 4.5% in 2003-2004 with an increase in 2015 to 9.9% (P = 0.002), possibly reflecting the increase of ZIKV incident cases reported over this period. (ox.ac.uk)
  • Diagnostic testing for Zika virus infection can be accomplished using both molecular and serologic methods. (cdc.gov)
  • For persons with suspected Zika virus disease, a positive real-time reverse transcription-polymerase chain reaction (rRT-PCR) result confirms Zika virus infection, but a negative result does not exclude infection. (cdc.gov)
  • Thus, a more conservative approach to interpreting PRNT results is now recommended to reduce the possibility of missing the diagnosis of either Zika or dengue virus infection. (cdc.gov)
  • Pregnant women with laboratory evidence of a recent Zika virus infection or flavivirus infection should be evaluated and managed for possible adverse pregnancy outcomes and reported to the appropriate Zika virus pregnancy registry. (cdc.gov)
  • Among flaviviruses, Zika and dengue virus share similar symptoms of infection, transmission cycles, and geographic distribution. (cdc.gov)
  • Pregnant women with laboratory evidence of Zika virus infection should be evaluated and managed for possible adverse pregnancy outcomes and be reported to the U.S. Zika Pregnancy Registry or the Puerto Rico Zika Active Pregnancy Surveillance System for clinical follow-up ( 9 , 10 ). (cdc.gov)
  • If serologic testing indicates recent flavivirus infection that could be caused by either Zika or dengue virus, patients should be clinically managed for both infections because they might have been infected with either virus. (cdc.gov)
  • 1) describe the epidemiology, clinical manifestation, management and prevention of Zika virus disease, 2) discuss diagnostic testing for Zika virus infection and interpretation of test results, 3) articulate the importance of early recognition and reporting of cases, 4) state the recommendations for pregnant women and possible Zika virus exposure, and 5) discuss evaluation of infants with microcephaly and relationship of Zika in microcephaly. (cdc.gov)
  • Although, the first confirmed Zika virus infection in Brazil were diagnosed in a returning traveller in March 2015. (wikipedia.org)
  • it is not known how many of these cases are associated with Zika virus infection. (cdc.gov)
  • The best way to prevent Zika virus infection is to avoid mosquito bites by avoiding exposure and eliminating mosquito breeding areas. (cdc.gov)
  • Health care providers should contact their state or local health department about testing patients with symptoms of Zika virus infection and a compatible travel history. (cdc.gov)
  • In addition to mosquito-to-human transmission, Zika virus infections have been documented through intrauterine transmission resulting in congenital infection, intrapartum transmission from a viremic mother to her newborn, sexual transmission, blood transfusion, and laboratory exposure ( 5 ). (cdc.gov)
  • The meetings provided up-to-date information on the current situation and agreed on a set of actions for the countries to undertake to enhance their preparedness and response capacities to Zika virus infection and its complications. (who.int)
  • Pregnant women who reside in areas with ongoing Zika virus transmission have an ongoing risk for infection throughout their pregnancy. (cdc.gov)
  • Health care providers should discuss reproductive life plans, including pregnancy intention and timing, with women of reproductive age in the context of the potential risks associated with Zika virus infection. (cdc.gov)
  • Evidence suggesting an association of Zika virus infection with an increased risk for congenital microcephaly and other abnormalities of the brain and eye ( 5 ) prompted the World Health Organization to declare the Zika virus outbreak a Public Health Emergency of International Concern on February 1, 2016 ( http://www.who.int/mediacentre/news/statements/2016/1st-emergency-committee-zika/en/ external icon ). (cdc.gov)
  • There is currently no vaccine or medication to prevent Zika virus infection. (cdc.gov)
  • Zika virus infection during pregnancy can cause microcephaly (a serious birth defect), eye abnormalities, and a number of developmental impairments termed congenital Zika syndrome. (msdmanuals.com)
  • Prevention involves avoiding mosquito bites, avoiding unprotected sex with a partner at risk of having Zika virus infection, and, for pregnant women and their partners, avoiding travel to areas with ongoing transmission. (msdmanuals.com)
  • A. albopictus is thought to be a secondary vector of epidemic Zika virus infection in the tropics, but whether it would do so in the more temperate climate of the United States is unclear. (msdmanuals.com)
  • In 2016 and 2017, cases of locally transmitted Zika virus infection were reported in Miami-Dade County in southeastern Florida and Brownsville, Texas. (msdmanuals.com)
  • Following infection with one serotype, subsequent infection with a different serotype increases a person's risk of severe dengue and death. (paho.org)
  • Many medically important and emergent arboviruses (arthropod-borne viruses) originated in non-human primates (NHPs), which typically show no clinical signs of infection but become viraemic and help maintain the virus in nature [ 1 ]. (biomedcentral.com)
  • As the weather begins to warm across the United States, the Centers for Disease Control and Prevention wants pediatricians to know how to recognize, diagnose, and treat Zika virus infection. (contemporarypediatrics.com)
  • Pediatric health care providers should work closely with obstetric providers to identify infants whose mothers were potentially infected with Zika virus during pregnancy (based on travel to or residence in an area with Zika virus transmission [ http://wwwnc.cdc.gov/travel/notices ]), and review fetal ultrasounds and maternal testing for Zika virus infection (see Interim Guidelines for Pregnant Women During a Zika Virus Outbreak*) ( 1 ). (blogspot.com)
  • or 2) infants born to mothers with positive or inconclusive test results for Zika virus infection. (blogspot.com)
  • For infants with laboratory evidence of a possible congenital Zika virus infection, additional clinical evaluation and follow-up is recommended. (blogspot.com)
  • Zika virus infections have also been documented through both intrauterine transmission resulting in congenital infection and intrapartum transmission from a viremic mother to her newborn ( 5 , 6 ). (blogspot.com)
  • The Brazil Ministry of Health has reported a marked increase from previous years in the number of infants born with microcephaly and intracranial calcifications in 2015, although it is not known how many of these cases are associated with Zika virus infection ( 6 , 8 - 11 ). (blogspot.com)
  • The diagnosis of Zika virus infection is made through molecular and serologic testing ( 2 ). (blogspot.com)
  • 2. Musso D, Ko AI, Baud D. Zika Virus Infection - After the Pandemic. (rjppd.org)
  • Pathophysiology and Mechanisms of Zika Virus Infection in the Nervous System. (rjppd.org)
  • A review on Zika virus outbreak, epidemiology, transmission and infection dynamics. (rjppd.org)
  • Zika virus infection experimentally induced in a human volunteer, 442-448. (rjppd.org)
  • Zika virus infection with prolonged maternal viremia and fetal brain abnormalities. (rjppd.org)
  • Another drawback of PRNT is that it has difficulties distinguishing the infecting virus (primary) in people with, or vaccinated against, a secondary infection. (healthresearch.org)
  • The ability of a pathogenic virus to lie dormant within a cell (latent infection). (lookformedical.com)
  • COVID-19 has opened new spectrums of infection and virus-host interactions. (jmitra.co.in)
  • Antigen Testing in ELISA Unlike any other viral infection, COVID-19 brought in its own set of challenges. (jmitra.co.in)
  • One strain of the virus caused the first wave of COVID-19 infection. (jmitra.co.in)
  • Zika: Improved diagnostics for Zika virus infection in South America through an established laboratory partnership between Brazil, Colombia and the UK. (ukri.org)
  • Based on differential tests returned on 6 September 2021, the results of three cases are consistent with a recent Yellow fever infection. (outbreaknewstoday.com)
  • Two other cases had cross-reactions with other flaviviruses, one of which was more consistent with dengue and one with a flavivirus infection (PRNT positive for Yellow fever, Zika, and dengue). (outbreaknewstoday.com)
  • 4) Cotton-rats, guineapigs and rabbits show no clinical signs of infection after intracerebral inoculation of late passage mouse brain virus. (paho.org)
  • 5) Monkeys develop an inapparent infection after subcutaneous inoculation with mouse brain virus. (paho.org)
  • Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207-IHU Méditerranée Infection), Marseille, France. (ox.ac.uk)
  • People infected with Zika can transmit the virus to their sexual partners. (wikipedia.org)
  • For symptomatic patients, it is important for providers to place separate testing orders for other arbovirus testing (dengue and chikungunya). (phila.gov)
  • d WHO Collaborating Centre for Arbovirus Reference and Research (Dengue/Severe Dengue), Tropical Infectious Diseases Research and Education Centre, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. (who.int)
  • Whereas population-level effects on birds during arbovirus outbreaks are well described, the underlying individual-level dynamics (e.g. movement, immunity, mortality) and the interactions between virus, vector and host that drive population-level effects have received less attention. (onehealthpact.org)
  • Percentage de novo seroconversion of Zika virus and CHIKV in different assays per time point. (cdc.gov)
  • Researchers generally believe the virus was brought to Brazil by an infected traveler who had been exposed to the virus in French Polynesia, who was then bitten by a mosquito that then infected others. (wikipedia.org)
  • Zika virus is a mosquito-borne flavivirus that was first identified in Uganda in 1947 ( 1 ). (cdc.gov)
  • These imported cases might result in local human-to-mosquito-to-human spread of the virus in limited areas of the continental United States that have the appropriate mosquito vectors. (cdc.gov)
  • All travelers to or residents of areas with ongoing Zika virus transmission should be advised to strictly follow steps to avoid mosquito bites because of the potential for exposure to Zika, dengue, and chikungunya viruses ( 6 ). (cdc.gov)
  • To prevent human-to-mosquito-to-human transmission, persons infected with Zika, dengue, or chikungunya virus should protect themselves from mosquito exposure during the first week of illness. (cdc.gov)
  • The Zika virus is a mosquito-borne flavivirus that is antigenically and structurally similar to the viruses that cause dengue, yellow fever, and West Nile virus. (msdmanuals.com)
  • Dengue is transmitted by the bite of an infected mosquito. (paho.org)
  • is the vector mosquito for dengue and is widely distributed in the Americas. (paho.org)
  • It is transmitted by the bite of a mosquito infected with one of the four serotypes of dengue virus. (paho.org)
  • Zika: the origin and spread of a mosquito-borne virus. (rjppd.org)
  • The tests' validation studies will be performed in collaboration with the Texas Department of State Health Services and the Harris County Mosquito Control District. (utmb.edu)
  • Soon after, when the mosquito feeds on a person, the virus gets transmitted to the person. (practo.com)
  • The Food and Drug Administration has approved the world's first vaccine to prevent chikungunya, a mosquito-borne illness that can cause debilitating joint pain for months to years. (mvcac.org)
  • Usutu virus (USUV) is a mosquito-borne zoonotic virus and one of the causes of flavivirus encephalitis in birds and occasionally in humans. (frontiersin.org)
  • Last decades, Europe has witnessed (re-)emergence of multiple zoonotic mosquito-borne viruses for which bird populations act as important reservoirs. (onehealthpact.org)
  • BACKGROUND: We evaluated dengue presentation by age, the performance of the 2015 Pan American Health Organization (PAHO) case criteria in identifying dengue cases, and variables to improve specificity. (cdc.gov)
  • This paper is the introduction to Special Collection of 10 papers on the epidemiology and ecology of emerging and lesser-known viruses of public and veterinary importance within the United States. (mvcac.org)
  • PHILADELPHIA-Integral Molecular, a leader in providing safe, off-the-shelf Reporter Virus Particles (RVPs) to study vaccine efficacy, has expanded its extensive portfolio with RVPs for influenza strains recently recommended by WHO for 2023/2024 seasonal influenza vaccines. (integralmolecular.com)
  • With excellent reproducibility and ease of use, RVPs are commonly used as critical reagents for high-throughput testing of hundreds or thousands of samples in vaccine efficacy trials. (integralmolecular.com)
  • Immunogenicity testing has been completed and a vaccine candidate selected. (ivi.int)
  • Frequently observed amino acid mutations in spike, especially receptor binding domain, will be constructed to test cross-neutralization effect of COVID-19 vaccine candidates. (ivi.int)
  • However, they exhibit reduced specificity through cross-reactivity against other flaviviruses, e.g. dengue, circulating in South America. (ukri.org)
  • ELISA ratios and plaque-reduction neutralization test titers of 14 Zika virus-positive patients, Brazil, 2016. (cdc.gov)
  • If immunoglobulin (Ig) M test results are positive, equivocal, or inconclusive, performing a plaque reduction neutralization test (PRNT) is needed to confirm the diagnosis. (cdc.gov)
  • Identification of dengue viruses from the Caribbean by plaque-reduction neutralization test. (microbiologyresearch.org)
  • According to the World Health Organization (WHO), on 13 August 2021, five Yellow fever cases tested positive by plaque reduction neutralization test (PRNT) at Intitut Pasteur in Dakar. (outbreaknewstoday.com)
  • An estimated 80% of persons who are infected with Zika virus are asymptomatic ( 2 ). (cdc.gov)
  • During the current outbreak in Brazil, Zika virus RNA has been identified in specimens (i.e., brain tissue, placenta, and amniotic fluid) from several infants with microcephaly and from fetal losses in women infected with Zika virus during pregnancy ( 6 , 8 , 9 ). (blogspot.com)
  • Most Zika virus infections are asymptomatic ( 12 ). (cdc.gov)
  • In approximately one in five cases, Zika virus infections result in Zika fever, a minor illness that causes symptoms such as fever and a rash. (wikipedia.org)
  • Phylogenetic analysis of the first Brazilian infections have strongly indicated that the circulating virus is the Asian, rather than African, strain of the virus, and was genetically similar to the virus found in the outbreak in French Polynesia. (wikipedia.org)
  • Although local transmission of Zika virus has not been documented in the continental United States, infections have been reported among travelers visiting or returning to the United States, and these likely will increase. (cdc.gov)
  • Although local transmission of Zika virus has not been documented in the continental United States, Zika virus infections have been reported in returning travelers ( 7 ). (cdc.gov)
  • Infections can be caused by a wide range of pathogens , most prominently bacteria and viruses . (wikipedia.org)
  • Usutu virus (USUV), a neglected Old World flavivirus, causes annually reoccurring epizootics in the avian fauna and sporadic human infections. (frontiersin.org)
  • TWiV 1047: Long COVID and avian flu in ferrets September 24, 2023 TWiV explains a study of postacute sequelae of COVID-19 at 2 years, and airborne transmission of human-isolated avian H3N8 influenza virus between ferrets. (microbe.tv)
  • Then, in May 2015, researchers from the Federal University of Bahia and the Evandro Chagas Institute determined, using the RT-PCR technique, that the illness was an outbreak of Zika virus. (wikipedia.org)
  • Although serologic evidence indicated additional human exposure during subsequent decades in parts of Africa and Asia, before the 2007 Yap Islands Zika virus outbreak, only 14 cases of human Zika virus disease had been documented. (wikipedia.org)
  • However, the outbreak in French Polynesia is known to have peaked and declined precipitously by February 2014, lending doubt to the suggestion the virus arrived later that year in Brazil with spectators and competitors. (wikipedia.org)
  • CDC has updated its interim guidelines for U.S. health care providers caring for pregnant women during a Zika virus outbreak ( 1 ). (cdc.gov)
  • The Zika virus outbreak continues to spread ( http://www.cdc.gov/zika/geo/index.html ), with ongoing Zika virus transmission recently reported in U.S. territories. (cdc.gov)
  • While the symptoms resembled dengue fever, testing ruled out this and several other potential causes. (wikipedia.org)
  • Clinical symptoms activity with multiple and large outbreaks occurring resemble dengue, and while chikungunya is a generally yearly. (who.int)
  • The symptoms of yellow fever occur three to six days after the exposure to the virus. (practo.com)
  • Monitor your symptoms and do get an RT-PCR test done if you found yourself facing symptoms suggestive of COVID-19 The Delta variant In view of the growing COVID-19 pandemic throughout the world, health officials are evaluating certain coronavirus mutations and variants that could be more contagious or deadly than the original strain. (metropolisindia.com)
  • Diagnosis is based on symptoms, laboratory testing, and travel history. (outbreaknewstoday.com)
  • Also, Dhori virus antigen has been tested against 3 or 4 immune sera to other tick-borne agents without evidence of a relationship (Casals, J. 1970. (cdc.gov)
  • Control cultures infected with dengue-3 at the same multiplicity contained dengue-3 antigen in greater than 90% of the cells. (microbiologyresearch.org)
  • A small population of cells was also found (about 1%) that contained type-specific antigen of both dengue virus types. (microbiologyresearch.org)
  • In this test procedure, recombinant HIV antigen is immobilized in the test line region of the device. (frenovobio.com)
  • This mixture migrates chromatographically along the length of the test strip and interacts with the immobilized HIV antigen. (frenovobio.com)
  • However, it shows a notable local drop in CAI around the 50th codon in all dengue serotypes. (bvsalud.org)
  • If IgM testing for dengue and chikungunya is indicated, commercial laboratory testing should be pursued. (phila.gov)
  • While the PADOH laboratory can conduct PCR testing for dengue and chikungunya, they do not offer dengue and chikungunya IgM testing. (phila.gov)
  • Local health officials should determine when to implement testing of asymptomatic pregnant women based on information about levels of Zika virus transmission and laboratory capacity. (cdc.gov)
  • Accurate laboratory testing is a critical component of dengue and chikungunya surveillance and control. (who.int)
  • RVPs are "pseudoviruses" lacking viral components that enable replication, and so are safe under standard (BSL2) laboratory conditions, unlike many viruses or pandemic strains that require restrictive and limited (BSL4) facilities. (integralmolecular.com)
  • Taking advantage of this expertise we also developed a diagnostic test for Zika virus that does not require sophisticated equipment or extensive laboratory personnel training. (utmb.edu)
  • Tests, protocols and training will be available to local laboratory networks for patient use and to support further diagnostic studies. (ukri.org)
  • Test [PRNT] and Non-structural protein 1 [NS1] ELISA) and assess the time-frame postinfection that portable NAAT provide accurate diagnosis. (ukri.org)
  • this population is not likely to qualify for access to confirmatory plaque reduction neutralization testing (PRNT) and therefore the virus could go undetected. (healthresearch.org)
  • Confirmatory PRNT is expensive, time-consuming (one-week turn-around), has low sample throughput, and uses live virus in the lab, which creates a biosafety risk. (healthresearch.org)
  • French researchers speculated the virus arrived shortly afterwards, in August 2014, when canoeing teams from French Polynesia, New Caledonia, Easter Island, and the Cook Islands, which had been or were experiencing Zika outbreaks, attended the Va'a World Sprint Championships in Rio de Janeiro. (wikipedia.org)
  • In light of the recent outbreaks in the Americas, the number of Zika virus disease cases among travelers visiting or returning to the United States is likely to increase. (cdc.gov)
  • During outbreaks, humans are the primary amplifying host for Zika virus. (cdc.gov)
  • In the Western Pacific Region in 2014 alone, milder disease, debilitating sequelae such as persistent there were outbreaks involving 1513 dengue cases arthralgia have been reported in 36-64% of cases. (who.int)
  • In 1947, the Zika virus was first isolated from monkeys in the Zika Forest of Uganda but was not considered an important human pathogen until the first large-scale outbreaks in the South Pacific islands in 2007. (msdmanuals.com)
  • Has the threat of Zika virus outbreaks come to an end? (rjppd.org)
  • This is important because the results of Zika and dengue virus testing will guide clinical management. (cdc.gov)
  • Updated guidelines include a new recommendation to offer serologic testing to asymptomatic pregnant women (women who do not report clinical illness consistent with Zika virus disease) who have traveled to areas with ongoing Zika virus transmission. (cdc.gov)
  • For pregnant women with clinical illness consistent with Zika virus disease,* testing is recommended during the first week of illness. (cdc.gov)
  • To confirm the dengue out-break from suspected clinical samples with the help of molecular diagnostic test (PCR/RT-PCR). (ncdc.gov.in)
  • Artemis Bioservices uses tailor-made and routinely developed assays for testing samples collected from animal studies and clinical studies. (artemisbioservices.com)
  • Our experience supplying the industry with RVPs reflecting the rapidly mutating SARS-CoV-2 virus enhanced our ability to quickly respond to evolving viral threats," said Kyle Doolan, PhD, Director of Research at Integral Molecular. (integralmolecular.com)
  • In contrast to most bacteria, fungi, or parasites, viruses are completely dependent on the host cell for their replication, hijacking the cell's biochemical machinery through the actions of viral genome-encoded factors. (genetex.com)
  • Attachment of a virus to a specific receptor on a host cell leads to internalization and frequently the initiation of a new round of viral replication. (genetex.com)
  • Included in this viral pathogen list are the influenza viruses, dengue virus, Japanese encephalitis virus (JEV), hepatitis viruses (e.g. (genetex.com)
  • I will be using viral neutralization assays to identify patterns in migratory birds throughout the annual cycle. (onehealthpact.org)
  • 2016 . Zika virus . (ajtmh.org)
  • 2016 . Evidence-based risk assessment and communication: a new global dengue-risk map for travellers and clinicians . (ajtmh.org)
  • An epidemic of Zika fever, caused by Zika virus, began in Brazil and affected other countries in the Americas from April 2015 to November 2016. (wikipedia.org)
  • It is estimated that 1.5 million people were infected by Zika virus in Brazil, with over 3,500 cases of infant microcephaly reported between October 2015 and January 2016. (wikipedia.org)
  • The specific event that brought the virus to Brazil was uncertain until March 2016. (wikipedia.org)
  • In March 2016, a study published in Science, which developed a "molecular clock" based on the count of virus mutations in a relatively small sample, suggested Zika virus arrived in the Americas (most likely in Brazil) from French Polynesia between May and December 2013, well before the World Cup and Va'a Championships. (wikipedia.org)
  • ABSTRACT Following the WHO declaration on 1 February 2016 of a Public Health Emergency of International Concern (PHEIC) with regard to clusters of microcephaly and neurological disorders potentially associated with Zika virus, the WHO Regional Office for the Eastern Mediterranean conducted three rounds of emergency meetings to address enhancing preparedness actions in the Region. (who.int)
  • PAHO/WHO provides advice and technical support for dengue prevention and control based on a regional strategy adopted by PAHO / WHO member States in 2016, called the " Strategy for arboviral disease prevention and control " (CD55.R6). (paho.org)
  • Questions are limited to clinicians who would like information related to Zika virus disease. (cdc.gov)
  • In December, the Ministry of Health estimated that 440,000-1,300,000 suspected cases of Zika virus disease had occurred in Brazil in 2015 ( 5 ). (cdc.gov)
  • The EMIPDA-QCM biosensor achieved low detection and quantitation limits of 0.091 µg mL-1 and 0.436 µg mL-1, respectively, allowing acute-phase detection of dengue and prognosis of the disease progression. (bvsalud.org)
  • Chikungunya disease usually presents with acute fever. (msdmanuals.com)
  • The disease can evolve into severe dengue, characterized by shock, shortness of breath, severe bleeding and / or complications in the organs. (paho.org)
  • Zika virus has been blamed for as many as 5000 cases of microcephaly in Brazil, and while it's not being spread locally throughout US states at this time, the Centers for Disease Control and Prevention (CDC) is urging pediatricians to familiarize themselves with the virus to help educate patients about the risks. (contemporarypediatrics.com)
  • As an arboviral disease, Zika virus disease is a nationally notifiable condition. (blogspot.com)
  • Virus shedding is an important means of vertical transmission (INFECTIOUS DISEASE TRANSMISSION, VERTICAL). (lookformedical.com)
  • Background: Ebola virus disease (EVD) remains a public health problem. (scirp.org)
  • The majority of care professionals had good knowledge of the name and reservoir of the causal agent, the severity of the disease, the modes of prevention and the attitude to adopt in case of suspicion of Ebola virus disease, and the year of the last epidemic. (scirp.org)
  • Strengthening care professionals capacity on Ebola virus disease is imperatively required in a short time, given epidemic episodes. (scirp.org)
  • Ebola virus disease (EVD) is an acute, severe and often fatal haemorrhagic fever caused by a Filoviridae virus. (scirp.org)
  • I believe it will be possible one day… to manufacture immunity in a test tube… mold little magic bullets to shoot into the bloodstream and destroy invading microbes… And what disease are you specifically going after with this magic bullet? (justhumanproductions.org)
  • About 15% of people infected with yellow fever virus will develop severe illness that can lead to liver disease, bleeding, shock, organ failure, yellowing skin (jaundice), and sometimes death. (outbreaknewstoday.com)
  • The illness can evolve to severe dengue, characterized by shock, respiratory distress, severe bleeding, and/or serious organ impairment. (paho.org)
  • Our ability to generate a panel of Influenza RVPs so quickly after the WHO announcement, again demonstrates our ability to respond rapidly with research tools that alleviate the burden of producing 'live' viruses. (integralmolecular.com)
  • Integral Molecular's seasonal Influenza RVPs represent specific strains for influenza A H1N1 and H3N2 and influenza B. Integral Molecular also offers a broad range of RVPs for other influenza strains including A H5N1 and H7N9, along with RVPs for an extensive selection of SARS-CoV-2 variants, and dengue, Zika, chikungunya, Ebola, and Nipah viruses. (integralmolecular.com)
  • The Ebola virus is highly contagious and lethal. (scirp.org)
  • Twenty-four national-level public health laboratories performed routine diagnostic assays on a proficiency testing panel consisting of two modules. (who.int)
  • RVPs display a quantitative and reproducible readout, enabling simple virus infectivity neutralization assays. (integralmolecular.com)
  • The quality of our assays is continuously monitored based on trending of positive controls, participation in proficiency testing and performance of internal in-process audits. (artemisbioservices.com)
  • Although A. aegypti feeds almost exclusively on humans, A. albopictus feeds on humans as well as variety of other animals that are not susceptible to the virus and are not involved in transmission chains. (msdmanuals.com)
  • Dengue incidence has increased in the Americas over the past four decades, from 1.5 million cumulative cases in the 1980s to 16,2 million in the decade 2010-2019. (paho.org)
  • This intervention forms the basis of an epidemiological study to assess the impact of operational deployment of wMel Wolbachia on the reduction of the incidence of notified dengue cases and virologically-confirmed dengue. (mvcac.org)
  • Specific molecular components of the cell capable of recognizing and interacting with a virus, and which, after binding it, are capable of generating some signal that initiates the chain of events leading to the biological response. (lookformedical.com)
  • Referred and suspected cases of HBV and HCV from different hospitals of Delhi and adjoining areas were confirmed by molecular diagnostic test (PCR/RT-PCR)targeting surface gene, core gene and 5'UTR gene region. (ncdc.gov.in)
  • To indicate the dengue virus type and genotype of the Dengue out-break with the help of molecular characterization and genotyping of dengue virus based on gene sequencing. (ncdc.gov.in)
  • The virus can be transmitted from a pregnant woman to her fetus, and can cause microcephaly and other severe brain anomalies in the infant. (wikipedia.org)
  • All patients with clinically suspected dengue should receive appropriate management to reduce the risk for hemorrhagic medical complications. (cdc.gov)
  • All patients with clinically suspected dengue should have proper management to reduce the risk for hemorrhage and shock ( 11 ). (cdc.gov)
  • Zika virus like other vector-borne diseases poses a particular challenge to the countries because of their complex nature which requires multidisciplinary competencies and strong rapid interaction among committed sectors. (who.int)
  • e WHO Collaborating Centre for Reference and Research on Tropical and Emerging Virus Diseases, Nagasaki University, Nagasaki, Japan. (who.int)
  • Virus diseases caused by the HERPESVIRIDAE. (lookformedical.com)
  • A general term for diseases produced by viruses. (lookformedical.com)
  • The site-specific imprinting approach not only enhanced the biosensing performance but also enabled a 26-fold cost reduction for biosensor functionalisation, providing a cost-effective strategy for label-free biosensing of the dengue biomarker via the biopolymer film. (bvsalud.org)
  • Note: This important study shows the establishment of the wMel Wolbachia and the companion paper shows the reduction of dengue in the treated cities. (mvcac.org)
  • Urban transmission cycles of arboviruses in densely populated tropical regions can result in explosive epidemics and pandemics, although there can also be low levels of transmission only sufficient to maintain the viruses in the population. (biomedcentral.com)
  • Detection of Mpox Virus Using Microbial Cell-free DNA: the Potential of Pathogen-Agnostic Sequencing for Rapid Identification of Emerging Pathogens. (amedeo.com)
  • CONCLUSIONS: The 2015 PAHO dengue case criteria had excellent sensitivity but poor specificity. (cdc.gov)
  • Low Zika Virus Seroprevalence in Vientiane, Laos, 2003-2015. (ox.ac.uk)
  • It appears Zika's route - from Africa and Asia to Oceania and then the Americas - may mirror that of chikungunya and dengue, both of which are now endemic in a large portion of the Americas. (wikipedia.org)
  • The Zika virus was first identified in a monkey in Uganda in 1947 and has been found since then along the equator throughout Africa and Asia. (contemporarypediatrics.com)
  • Zika virus in the Americas: Early epidemiological and genetic findings:345-349. (rjppd.org)
  • In 2008, PAHO / WHO Member States established a Network of Dengue Laboratories of the Americas (RELDA), to strengthen technical capacities for diagnosing dengue. (paho.org)
  • Until more is known, pregnant women should consider postponing travel to any area with ongoing Zika virus transmission. (cdc.gov)
  • Only Canada and continental Chile are free from dengue and its vector. (paho.org)
  • In May 2015, the World Health Organization reported the first local transmission of Zika virus in the Region of the Americas (Americas), with autochthonous cases identified in Brazil ( 4 ). (cdc.gov)
  • Contact PDPH at (215) 685-6742 for testing requests and to report suspected Zika cases who have had testing ordered. (phila.gov)
  • Additional efforts include tracing and testing household contacts of confirmed cases to improve household transmission data. (ivi.int)
  • Philadelphia-area healthcare providers are encouraged to utilize commercial laboratories when ordering Zika virus testing for exposed, symptomatic persons with health insurance. (phila.gov)
  • To conduct an external quality assessment (EQA) of dengue and chikungunya diagnostics among national-level public health laboratories in the Asia Pacific region following the first round of EQA for dengue diagnostics in 2013. (who.int)
  • Dengue prevention and control must be intersectoral and involve the family and the community. (paho.org)
  • Concern (PHEIC) with regard to clusters of microcephaly and neurological disorders potentially associated with Zika virus, the WHO Regional Office for the Eastern Mediterranean conducted three rounds of emergency meetings to address enhancing preparedness actions in the Region. (who.int)