Loading...
  • apical dendritic tree
  • Abnormalities include ectopic localization of newborn cells, de novo formation of abnormal basal dendrites, and disruptions of the apical dendritic tree. (iospress.com)
  • These results confirm the hypothesis that the broad spikes of MG cells originate in the soma and propagate through the molecular layer in the apical dendritic tree, and suggest the possibility that this backpropagation may contribute to `boosting' of the synaptic response in distal apical dendrites in certain circumstances. (biologists.org)
  • AMPA
  • Predictions were made for passive-cell current clamp recordings, combined AMPA and NMDA receptor responses, and local dendritic depolarization in response to unitary stimulations. (springer.com)
  • axonal
  • in which it is possible to study such complex integration in a meaningful functional context, and to clarify the computational roles of dendritic, somatic and axonal compartments. (biologists.org)
  • vitro
  • Using this technique in an ` in vitro ' interface slice preparation, we found that following either parallel fiber stimulation or an orthogonal field stimulus, a sink appeared in the ganglionic layer and propagated into the molecular layer. (biologists.org)
  • Broad action potentials can be evoked in vivo by either corollary discharge input or electrosensory input, and in vitro by parallel fiber stimulation. (biologists.org)
  • somatic
  • Here, excitatory synaptic activation is modeled to infer biophysical parameters, aid analysis interpretation, explore mechanisms, and formulate predictions by contrasting simulated somatic recordings with experimental data. (springer.com)
  • However, the integration of responses within multiple dendritic and somatic compartments, with different specific membrane properties, suggests complex computational mechanisms that are still poorly understood. (biologists.org)
  • neuronal
  • Magnetoencephalography (MEG) is a rapidly developing and unique tool for the study of brain function, in particular the underlying oscillations in neuronal activity that appear to be fundamental ( box 1 ), with real-time resolution and potential for application across a range of brain disorders. (bmj.com)
  • frequency
  • This study evaluated a mouse model of temporal lobe epilepsy to test which pathological changes in the dentate gyrus correlate with seizure frequency and help prioritize potential mechanisms for further study. (stanford.edu)
  • responses
  • Starburst amacrine cells did not display action potentials and the presence of a large, voltage-dependent outward current limited depolarizing responses to a maximum potential of about -40 mV. (nih.gov)
  • retina
  • Receptive field properties of starburst cholinergic amacrine cells in the rabbit retina. (nih.gov)
  • structures
  • Electrical potential changes related to brain activity measured at the scalp by EEG are fundamentally limited by the distortive effects of the intervening structures, which severely hamper efforts to localise the signal source precisely. (bmj.com)
  • describe
  • In the literature, discussion of different regions of thalamus uses the terms primary sensory, or 'specific' to describe the thalamic nuclei or regions that receive direct excitatory input from the periphery, eg. (frontiersin.org)
  • cells
  • Taken together, findings provide a strong rationale for continued work to elucidate the role of newborn granule cells in epilepsy: both to understand basic mechanisms underlying the disease, and as a potential novel therapy for epilepsy. (iospress.com)