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  • Inflammation
  • Chronic systemic inflammation (SI) is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system. (wikipedia.org)
  • Individuals susceptible to developing chronic systemic inflammation appear to lack proper functioning of Treg cells and TDCs. (wikipedia.org)
  • immunostimulatory
  • Productive infections are accompanied by the blunting of MDDC immunostimulatory abilities (HSV-1, HSV-2, CMV, KSHV), by a loss of cell viability (HSV-1, HSV-2), and by enhanced virus transmission to T cells (VZV). (frontiersin.org)
  • They found that the injected dendritic cells were able to process the tumor antigens at the tumor site, migrate to the lymph nodes, and present the antigens to the lymphoid cells, which released significant quantities of interferon-gamma, an immunostimulatory substance. (cancernetwork.com)
  • Since 1893, it has been recognized that Coley's toxin, a mixture of bacterial cell lysate, has immunostimulatory properties that could reduce the progression of some carcinomas, but it was not until 1983 that Tokunaga et al. (wikipedia.org)
  • chemokine
  • FDCs are among main producers of the chemokine CXCL13 which attracts and organises lymphoid cells. (wikipedia.org)
  • Activated B cells can migrate through body to respiratory and genito-uritary tract, because they express chemokine receptors CCR10 and α4β1-integrin. (wikipedia.org)
  • It was previously known as Pulmonary and activation-regulated chemokine (PARC), dendritic cell (DC)-chemokine 1 (DC-CK1), alternative macrophage activation-associated CC chemokine-1 (AMAC-1), and macrophage inflammatory protein-4 (MIP-4). (wikipedia.org)
  • Monoclonal
  • Monoclonal antibodies, such as pembrolizumab, may block tumor growth in different ways by targeting certain cells. (cancer.gov)
  • Charakterisierung einer Serie von monoklonalen Antikörpern gegen humane T-Zellen" [Characterization of a series of monoclonal antibodies against human T cells]. (wikipedia.org)
  • tissues
  • Factor Mfge produced in lymphoid tissues mainly by FDCs is known to enhance engulfment of apoptotic cells. (wikipedia.org)
  • citation needed] Non-microbial non-self antigens can include pollen, egg white and proteins from transplanted tissues and organs or on the surface of transfused blood cells. (wikipedia.org)
  • Negative selection refers to the identification and deletion (apoptosis) of self-reacting cells, that is T cells that may select for and attack self tissues. (wikipedia.org)
  • Human
  • 2007). An infectious origin of IDCS (Epstein-Barr virus or human herpesvirus), like others dendritic cells (DCs) neoplasms, has been dismissed (Saygin C et al. (atlasgeneticsoncology.org)
  • This led to the creation of five unofficial classes or categories of CpG ODN based on their sequence, secondary structures, and effect on human peripheral blood mononuclear cells (PBMCs). (wikipedia.org)
  • In human and mouse cells 11 H1 variants have been described and are encoded by single genes. (wikipedia.org)
  • They are encoded by genes within histone cluster 1 located in human cells on chromosome 6. (wikipedia.org)