• Poly(amidoamine), or PAMAM, is perhaps the most well known dendrimer. (wikipedia.org)
  • The functional group on the surface of PAMAM dendrimers is ideal for click chemistry, which gives rise to many potential applications. (wikipedia.org)
  • This study was carried out to evaluate the in vitro effect of a whole generation poly(amidoamine) (PAMAM) dendrimer (G3.0) on dentinal tubule occlusion by inducing mineralization within dentinal tubules. (jove.com)
  • Dentin discs were treated with PAMAM dendrimers using two methods, followed by the in vitro characterization using Attenuated total reflection Fourier-transform infrared spectroscopy (ATR-FTIR), X-ray diffraction (XRD), Field emission scanning electron microscopy (FE-SEM) and Energy-Dispersive X-ray Spectroscopy (EDS). (jove.com)
  • These results showed that G3.0 PAMAM dendrimers coated on dentin surface and infiltrated in dentinal tubules could induce hydroxyapatite formation and resulted in effective dentinal tubule occlusion. (jove.com)
  • Moreover, crosslinked PAMAM dendrimers could induce the remineralization of demineralized dentin and thus had the potential in dentinal tubule occlusion. (jove.com)
  • In this in vitro study, dentinal tubules occlusion could be achieved by using PAMAM dendrimers. (jove.com)
  • While Macrophen and Double Macrophen were the most active substances among polyamino-phenolic ligands, dendrimers were overall twofold more effective than all other compounds with a reduction up to 85 and 73% of legionella and multi-species biofilms, respectively. (frontiersin.org)
  • These data suggest that the studied compounds, especially dendrimers, could be considered as novel molecules in the design of research projects aimed at the development of efficacious anti-biofilm disinfection treatments of water systems in order to minimize legionellosis outbreaks. (frontiersin.org)
  • The concentration of the chemicals tested as anti-biofilm agents was chosen based on cytotoxicity assays: the highest non-cytotoxic chemical concentration was used for biofilm inhibition assays, with dendrimer concentration 10-fold higher than polyamino-phenolic ligands. (frontiersin.org)
  • Chemical interaction with matrix molecules is hypothesized, based on SEM images and considering the low or absent anti-microbial activity on planktonic bacteria showed by flow cytometry. (frontiersin.org)
  • Nanomaterials have unusual mechanical, optical, electrical and chemical behaviors, they have been widely used in medicine and pharmaceuticals for the sensitive detection of key biological molecules, more precise and safer imaging of diseased tissues, and novel forms of therapeutics etc. (degruyter.com)
  • Branching may result from the formation of carbon-carbon or various other types of covalent bonds. (wikipedia.org)
  • Dendrimer popularity then greatly increased, resulting in more than 5,000 scientific papers and patents by the year 2005. (wikipedia.org)
  • In this work we introduce the development of dendrimer-based sensors and present a procedure for pH measurement in vitro , in living cells and in vivo . (jove.com)
  • It has been suggested that back folding of the terminal branches leads to a more uniform or even reverse density profile (Fig.6). (pharmainfo.net)
  • In free radical polymerization, branching occurs when a chain curls back and bonds to an earlier part of the chain. (wikipedia.org)