• Fertilization, polyspermy, embryo quality, and pregnancy outcomes were not significantly different between both groups. (ecerm.org)
  • Despite considerable technological advancements, polyspermy remains a significant challenge in in-vitro fertilization (IVF) procedures in pigs, disrupting normal embryonic development. (e-jarb.org)
  • Collectively, these results demonstrate that various fertilization conditions, including modified co-culture period, active sperm separation, and culture medium volume, enhance fertilization efficiency and subsequent embryonic development by decreasing polyspermy occurrence. (e-jarb.org)
  • This study aimed to investigate the effects of early and late cumulus cell removal on fertilization, polyspermy, embryonic development potential, blastocyst development, and clinical outcomes. (ecerm.org)
  • While alkaloids often exert unique pharmacological effects on animal cells, exposure of sea urchin eggs to nicotine causes polyspermy at fertilization in a dose-dependent manner. (mdpi.com)
  • Compared with other groups, sperms treated with melatonin demonstrated hyperactivity, and the fertilization rate was significantly increased. (vetmedmosul.com)
  • Here, we aimed to determine whether optimal fertilization conditions reduce the polyspermy incidence in pigs. (e-jarb.org)
  • Early cumulus cell removal at 6 hours had no significant difference in fertilization, polyspermy, embryo development, or obstetric and perinatal outcomes compared to late removal. (ecerm.org)
  • Polyspermy is the condition when multiple sperm fuse with a single egg. (wikipedia.org)
  • A 2002 study demonstrated that mammalian sperm contain PLC zeta which can start the signaling cascade. (wikipedia.org)
  • Such cytoskeletal changes appeared to render the eggs more receptive to sperm, as judged by the significant alleviation of polyspermy by latrunculin-A and mycalolide-B. In addition, our fluorimetric assay provided the first evidence that nicotine directly accelerates polymerization kinetics of G-actin and attenuates depolymerization of preassembled F-actin. (mdpi.com)
  • Although the 6 h sperm-free cultured group had a higher penetration rate than the 5 h cultured group, the polyspermy rate significantly increased in the 6 h sperm-free cultured group. (e-jarb.org)
  • On the other hand, a more recent study in 2018 caused a stir in the scientific community by demonstrating that men who wore boxers had 17 percent more sperm compared to those in briefs. (spermcountreport.com)
  • Our results, along with those on Otx - and Hox -gene expression, demonstrate that the cephalopod condition is similar to that in mouse and fruit fly, with Otx being expressed in the anterior-most brain region (except for the vertical lobe) and a Pax2/5/8 expression domain separating the Otx -domain from a Hox -gene-expressing posterior brain region. (biomedcentral.com)
  • Previous studies have demonstrated that transcription factors such as Pax genes play important roles during their development. (biomedcentral.com)
  • In sea urchins, the block to polyspermy comes from two mechanisms: the fast block and the slow block. (wikipedia.org)
  • The fast block is an electrical block to polyspermy. (wikipedia.org)
  • Following fertilization, the ZP undergoes changes described as 'hardening', which prevent multiple sperm from fertilizing the egg and thereby establish a block to polyspermy. (edu.au)
  • Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy. (betalifesci.com)
  • Zinc sparks induce physiochemical changes in the egg zona pellucida that prevent polyspermy [1] "During fertilization or chemically-induced egg activation, the mouse egg releases billions of zinc atoms in brief bursts known as 'zinc sparks. (edu.au)