Deliver drugs. Medical search. Frequent questions

The discovery, published today in Nature Communications, provides a means of homing drugs or nanoparticles to injured areas of the brain. (eurasiareview.com)
Not only did we show that CAQK carries drug-sized molecules and nanoparticles to damaged areas in mouse models of acute brain injury, we also tested peptide binding to injured human brain samples and found the same selectivity," added Mann. (eurasiareview.com)
And, because the peptide can deliver nanoparticles that can be loaded with large molecules, it could enable enzyme or gene-silencing therapies. (eurasiareview.com)
New skin patch technology, based on stretchable electronics, nanomembranes, and nanoparticles, developed by scientists in Korea and U.S., has the potential to provide continuous movement monitoring and drug delivery in a device the size of a bandage. (medgadget.com)
Silicon nanomembranes have been fabricated to act as movement sensors and silica nanoparticles, activated by heat to release their payloads, can hold therapeutic drugs. (medgadget.com)
The produced drug loaded nanoparticles were checked for drug release pattern and hemolysis assays. (ssrn.com)
In a paper scheduled to be published in the nanoscience journal Small in June, researchers from UCLA?s California NanoSystems Institute and Jonsson Cancer Center report a novel approach using silica-based nanoparticles to deliver the anticancer drug camptothecin and other water-insoluble drugs into human cancer cells. (spiritindia.com)
Tamanoi and Zink devised a method for incorporating the representative hydrophobic anticancer drug camptothecin into the pores of fluorescent mesoporous silica nanoparticles and delivering the particles into a variety of human cancer cells to induce cell death. (spiritindia.com)
The results suggest that the mesoporous silica nanoparticles might be used as a vehicle to overcome the insolubility problem of many anticancer drugs. (spiritindia.com)
We have successfully loaded hydrophobic anticancer drugs into mesoporous nanoparticles and delivered them into human cancer cells to induce cell death. (spiritindia.com)
To overcome these problems, drug delivery systems using pegylated polymers, liposomal particles or albumin-based nanoparticles have been developed. (spiritindia.com)
The blue spheres represent lipids, a kind of fat molecule, surrounding a central cavity containing magnetic nanoparticles (black) and the drug to be delivered (red). (mit.edu)
When the nanoparticles are heated, the drug can escape into the body. (mit.edu)
When placed inside a high-frequency but low-strength magnetic field, the nanoparticles heat up, warming the lipids and making them undergo a transition from solid to liquid, which makes the layer more porous - just enough to let some of the drug molecules escape into the surrounding areas. (mit.edu)
Iron oxide nanoparticles that can track drug delivery will provide the possibility to adapt treatments for individual patients," said Associate Professor Cyrille Boyer from the UNSW School of Chemical Engineering. (rdworldonline.com)
However, there are limited studies describing how to load chemotherapy drugs onto the surface of magnetic iron oxide nanoparticles, and no studies that have effectively proven that these drugs can be delivered inside the cell. (rdworldonline.com)
The MSN nanoparticles used have the potential for carrying and delivering therapeutic agents to highly specific target sites of the respiratory tract. (cdc.gov)
In this article, the authors described the design of mesoporous silica nanoparticles which could act as carriers for drugs. (cdc.gov)

By melding magnetic and luminescent properties with an easily modified surface, a team of investigators at the National Research Council of Canada have created what could prove to be a highly versatile nanoparticle system for imaging and delivering drugs to tumors. (news-medical.net)
Currently, the team is testing this approach to treat tumors in mice and working on ways to deliver the antibodies to specific types of cells. (bostonmagazine.com)
One of the biggest challenges in cancer therapy is being able to sufficiently deliver chemotherapy drugs to tumors without exposing healthy tissues to their toxic effects. (innovationtoronto.com)
Yet while nanocarriers do a good job protecting healthy tissues, the amount of drug successfully delivered to tumors remains low. (innovationtoronto.com)
With funding support from NIBIB and others, Martel's research team conducted a series of experiments to show that the bacteria's unique navigation system could be exploited to more efficiently deliver drugs to tumors. (innovationtoronto.com)
Next, the researchers wanted to see whether attaching vesicles loaded with drugs to the cells would affect their movement into the tumors. (innovationtoronto.com)
For comparison, some researchers estimate that only approximately 2% of drugs delivered via current nanocarriers make it into tumors. (innovationtoronto.com)
The resulting drug, Herceptin, has been successfully used to treat breast tumors that overexpress the HER2 receptor. (globalbiodefense.com)

Finally, the second silica layer provided a surface to which targeting and drug molecules could be attached easily. (news-medical.net)
What we've been doing for the past three years is figuring out how you can deliver molecules into cells. (bostonmagazine.com)
The method may be prolonged to carry various drug molecules against varied biological targets. (healthjockey.com)
recently researchers have started exploring the possibility of mimicking this system to deliver small protein molecules as vaccines. (globalbiodefense.com)
The structural complexity of these molecules requires careful handling to ensure integrity and stability of the drug. (lu.se)

The Centers for Disease Control and Prevention (CDC) is working to make it easier for U.S. healthcare providers to request TPOXX (also called tecovirimat), an antiviral drug that can be used under special circumstances to treat patients with monkeypox. (cdc.gov)

The researchers have turned a deadly protein into a carrier for antibody drugs. (bostonmagazine.com)
A team of MIT researchers are using a disarmed version of anthrax to administer cancer drugs. (bostonmagazine.com)
Pentelute, the senior author of the paper, says that this is the first demonstration of effective delivery of antibody mimics into cells, which could allow researchers to develop new drugs for cancer and many other diseases. (bostonmagazine.com)
Now-a-days, researchers are also using novel ways to deliver these drugs into the body. (healthjockey.com)
Pertaining to that, researchers at UC Santa Barbara have supposedly developed an innovative way to carry drugs into cancer cells by exposing them temporarily to a non-harmful laser. (healthjockey.com)
Researchers at UCLA have successfully manipulated nanomaterials to create a new drug-delivery system that promises to solve the challenge of the poor water solubility of today?s most promising anticancer drugs and thereby increase their effectiveness. (spiritindia.com)
Researchers funded in part by NIBIB have recently shown that magnetic bacteria are a promising vehicle for more efficiently delivering tumor-fighting drugs. (innovationtoronto.com)
One way researchers have attempted to overcome this is by developing nanocarriers-extremely small particles packed with drugs. (innovationtoronto.com)
Now, researchers at the McGovern Institute at MIT and elsewhere have developed a system to deliver medical treatments that can be released at precise times, minimally-invasively, and that ultimately could also deliver those drugs to specifically targeted areas such as a specific group of neurons in the brain. (mit.edu)
With this latest study, the UNSW researchers engineered a new way of loading the drugs onto the nanoparticle's polymer surface, and demonstrated for the first time that the particles are delivering their drug inside the cells. (rdworldonline.com)
Johns Hopkins researchers are touting microdevices that can latch onto intestinal mucosa and release drugs into the body. (drugdeliverybusiness.com)
Researchers said the findings were "intriguing" and called for mass trials on healthy populations to see if the drug should be routinely prescribed. (telegraph.co.uk)
A team of MIT researchers has now hijacked that delivery system for a different purpose: administering cancer drugs. (globalbiodefense.com)

We wondered if we could render anthrax toxin nontoxic, and use it as a platform to deliver antibody drugs into cells. (bostonmagazine.com)
Several antibody drugs have been developed to target other receptors found on cancer-cell surfaces. (globalbiodefense.com)

The World Health Organization delivered anti-epileptic drugs to the Central Drugs Store of the Palestinian Ministry of Health in Gaza 7 Sep 2018, Gaza - The World Health Organization delivered anti-epileptic drugs to the Central Drugs Store of the Palestinian Ministry of Health in Gaza on Wednesday 6 September. (who.int)
Guidelines for the storage of essential medicines and other health commodities / John Snow, Inc./DELIVER in collaboration with the World Health Organization. (who.int)

Magnetic particles allow drugs to be released at precise times and in specific areas. (mit.edu)
The drug of choice is encapsulated within these bubbles, and can be released by applying a magnetic field to heat up the particles, allowing the drug to escape from the liposome and into the surrounding tissue. (mit.edu)

On May 11, 2019, Cuong was informed by Roem that there was a package to deliver the day after, for which he would be paid VND120 million ($5,160). (vnexpress.net)
Meanwhile, Wildman questioned whether a number of ledgers which were seized in the United States were based on testimony from convicted drug trafficker Dean Drummond, who previously testified against the defendants via video link in 2019. (jamaica-gleaner.com)
The Supreme Court granted a stay of the trial on September 19, 2019, which came into effect later that month after Drummond, a key prosecution witness currently serving a 27-year prison sentence in the United States for drug smuggling, gave evidence against the four defendants. (jamaica-gleaner.com)
Provisional data in the United States shows that the reported number of drug overdose deaths occurring in the United States decreased by 0.9% from the 12 months ending in September 2018 to the 12 months ending in September 2019, from 68,421 to 67,839. (cdc.gov)

FOP has no treatment, but doctors may prescribe drugs to relieve pain and swelling. (fiercebiotech.com)
Although the doctor at Sunshine Coast Health Centre had the appropriate training, the province had not yet granted him the required exemption to prescribe the drug. (cbc.ca)

In a new paper published in the journal ChemBioChem , Pentelute and his team showed that they could not only disarm the anthrax toxin, but use it to deliver two proteins that can kill cancer cells. (bostonmagazine.com)
Many drugs, especially those made of proteins, cannot be taken orally because they are broken down in the gastrointestinal tract before they can take effect. (mit.edu)
Delivering proteins is the holy grail of drug delivery. (mit.edu)
In a paper appearing in the journal ChemBioChem , Pentelute and colleagues showed that they could use this disarmed version of the anthrax toxin to deliver two proteins known as antibody mimics, which can kill cancer cells by disrupting specific proteins inside the cells. (globalbiodefense.com)

For example cellular focusing on of antibodies or specific ligands is based on the capability of the focusing on providers to selectively bind to the cell surface to result in receptor-mediated endocytosis.3 5 Thus the drug delivery system along with the therapeutic agent would be delivered to the interior of a given cell type. (exposed-skin-care.net)
Psychoactive drugs have different degrees of restriction of availability, depending on their risks to health and therapeutic usefulness, and classified according to a hierarchy of schedules at both national and international levels. (bvsalud.org)

Inhalation of pentamidine delivers the drug directly to your lungs. (medlineplus.gov)
This drug-carrier inhalation nanotechnology should potentially be useful in human clinical setting in the future. (cdc.gov)

On Sept. 27, task force agents interviewed a cooperating witness who alleged Muñoz tried to recruit him to transport multi-kilogram amounts of illicit drugs from El Paso to the interior of the United States for $2,000 a trip, documents filed in U.S. District Court for the Western District of Texas show. (wkbn.com)
Federal officials also are seeking forfeiture of the cash and property either purchased with illicit proceeds or used in the transportation of illegal drugs. (wkbn.com)
The primary objective of the National Pregnancy and Health Survey (NPHS) was to produce national annual estimates of the percentages and numbers of mothers of live newborns in the United States who used selected licit and illicit drugs in the 12 months prior to delivery. (data.gov)

It also seems that there will be a fully robotic pharmacy system, capable of labeling medicines as well as stocking supplies and picking up drugs. (blogspot.com)
This partnership has meant vital medicines were delivered to the most vulnerable residents within the community. (staffordshirefire.gov.uk)
The key parameters for successful treatment using nanodelivery systems are essential selectivity biological activity effectiveness of uptake and drug concentration.6 In basic principle nanoparticulate delivery systems can be used to target anticancer medicines to tumor cells by either passive or active targeting (Fig.?1). (exposed-skin-care.net)
The procurement of anti-epileptic drugs and other essential psychotropic medicines (medicines used in the treatment of mental health) for the occupied Palestinian territory is a main component of the EU-funded WHO project Building Palestinian resilience: improving psychosocial and mental health responses to emergency situations . (who.int)
In August, 50% of essential medicines, including anti-epileptic drugs, were critically depleted with less than a month's stock remaining, according to Gaza's Central Drugs Store. (who.int)
The procurement and delivery of essential medicines to treat mental illness forms a core component of the WHO Mental Health Project, which has utilized 800,000 Euros to deliver psychotropic medicines to the West Bank and Gaza in 2017-2018. (who.int)
In addition to the procurement and delivery of essential medicines, the Palestinian Ministry of Health with WHO has developed a national emergency mental health plan and intervention guidelines, and delivered training to health professionals on the Mental Health Gap Action Programme, as well as training on the provision of psychological first aid to emergency medical teams. (who.int)
Dept. of Essential Drugs and Medicines Policy. (who.int)

This peptide could be used to deliver treatments that limit the extent of damage. (eurasiareview.com)
In a step toward biomedical applications for these devices, Jiawen Li, Li Zhang, Dong Wu and colleagues wanted to develop shape-morphing microrobots that could be guided by magnets to specific sites to deliver treatments. (acs.org)
The ability to actively and precisely target drug delivery to a tumor will help reduce side effects and potentially improve the efficacy of treatments. (innovationtoronto.com)
Obtain advice on selecting alternative treatments from clinical or drug information pharmacists. (medscape.com)
Additional monitoring of the patient or plasma drug concentrations may be required when different treatments or formulations are used perioperatively. (medscape.com)

These risk factors may cause loss of efficacy and quality of the protein drug, potentially leading to patient safety concerns. (lu.se)

A second cooperating witness allegedly told the agents the cash found inside Muñoz's gray GMC Yukon in July was payment for an illegal drug delivery in Charlotte, federal officials allege in the documents. (wkbn.com)
Dr. Kaladhar Kamalasanan and Sharma, C. P., "Niomat- A Novel Solid Drug Delivery System to Deliver the Niosomes or Proniosomes with Drugs", Indo- Australian Conference on Biomaterials, Implantable Devices, Tissue Engineering and Regenerative Medicine (BITE & RM) (Poster). (amrita.edu)
Langer and Traverso have previously developed several novel strategies for oral delivery of drugs that usually have to be injected. (mit.edu)
Also, Traverso noted that pain receptors are lacking in this part of the body, potentially enabling pain-free micro-injections in the small intestine for delivery of drugs like insulin. (mit.edu)
We performed numerous safety tests on animal and human tissue to ensure that the penetration event allowed for drug delivery without causing a full thickness perforation or any other serious adverse events," Abramson says. (mit.edu)
The new capsule represents an important step toward achieving oral delivery of protein drugs, which has been very difficult to do, says David Putnam, a professor of biomedical engineering and chemical and biomolecular engineering at Cornell University. (mit.edu)
So we have a magnetic switch for drug delivery," and that amount of heat is small enough "so that you don't cause thermal damage to tissues," says Anikeeva, who also holds appointments in the departments of Materials Science and Engineering and the Brain and Cognitive Sciences. (mit.edu)
Sean Whooley is an associate editor who mainly produces work for MassDevice, Medical Design & Outsourcing and Drug Delivery Business News. (drugdeliverybusiness.com)
Need Drug Delivery Business News in a minute? (drugdeliverybusiness.com)
Drug Delivery Enewsletters get you caught up on all the mission critical news you need in med tech. (drugdeliverybusiness.com)
Implementing integrated services for prevention of HIV infection, viral hepatitis, STDs, and TB is intended to provide persons who use drugs illicitly with increased access to services, to improve timeliness of service delivery, and to increase effectiveness of efforts to prevent infectious diseases that share common risk factors, behaviors, and social determinants. (cdc.gov)
FROM THE CLINICAL EDITOR: Delivery of drugs via the respiratory tract is an attractive route of administration. (cdc.gov)

Muñoz in turn allegedly later would send photographs of the drugs to the other party, according to court records. (wkbn.com)
THE LONG-RUNNING trial of four businessmen who were arrested in 2013 for allegedly being involved in a drug-smuggling and money-laundering scheme between Jamaica and the United States will continue on September 29. (jamaica-gleaner.com)

the tumor microenvironment enhancing drug bioavailability and effectiveness due to the practical differences between normal and tumor cells. (exposed-skin-care.net)
Switching to an alternative formulation of the same drug may involve a change in dose due to differing bioavailability of the active drug. (medscape.com)

Gareth Musico , President of HUMANCONTACT, stated "Our approach to virtual events has been to re-imagine the traditional video call or stream experience and deliver engaging, interactive, and customized content to attendees at home. (agoracom.com)

On May 29, 2020, Avifavir received a registration certificate from the Ministry of Health of the Russian Federation and became the first Russian drug approved for treatment of COVID-19 patients. (pharmiweb.com)
Nov. 20, 2020 - ImagineAR (CSE: IP) (OTCQB: IPNFF) an Augmented Reality Company that enables sports teams, brands and businesses to instantly create their own mobile phone AR campaigns, is pleased to announce that it will work with Shoppers Drug Mart and the event production agency HUMANCONTACT Inc., to deliver an Immersive AR Experience to over 2500 Corporate Staff, Pharmacist-Owners, and Front Store Managers across Canada. (agoracom.com)

Each "theragripper," or dust-spec-sized microdevice made of metal and thin, shape-changing film and coated in a heat-sensitive paraffin wax, can potentially carry any drug and release it gradually into the body. (drugdeliverybusiness.com)

When the capsule reaches the small intestine, it breaks down to reveal dissolvable microneedles that attach to the intestinal wall and release drug for uptake into the bloodstream. (mit.edu)

On the other hand active focusing on involves the attachment of a moiety such as a monoclonal antibody or a ligand to deliver a drug to pathological sites or to cross biological barriers based on molecular acknowledgement processes. (exposed-skin-care.net)
Protein drugs, such as monoclonal antibodies, have proved successful in treating cancer and immune system diseases. (lu.se)

H umanitarian Elijah Ogeda, of the nonprofit Youth Art Development and Entrepreneurship Network, has long been troubled by what he calls the epidemic of drug abuse in Kenya. (drugfreeworld.org)

The drug carriers were engineered to be stable inside the body at the normal body temperature of 37 degrees Celsius, but able to release their payload of drugs at a temperature of 42 degrees. (mit.edu)
We've been working to solve this problem by designing these small drug carriers that can autonomously latch onto the intestinal mucosa and keep the drug load inside the GI tract for a desired duration of time. (drugdeliverybusiness.com)

Anthrax toxin is a professional at delivering large enzymes into cells," says Bradley Pentelute, the Pfizer-Laubauch Career Development assistant professor of chemistry at MIT. (bostonmagazine.com)

In hopes of coming up with an alternative to those injections, MIT engineers, working with scientists from Novo Nordisk, have designed a new drug capsule that can carry insulin or other protein drugs and protect them from the harsh environment of the gastrointestinal tract. (mit.edu)
Relevant protein drugs are chosen based on sales statistics within the hospital and the corresponding wards were observed. (lu.se)

The process to obtain medications from the SNS differs from the usual commercial means used by clinicians and healthcare care pharmacists to order other drugs. (cdc.gov)

Results of search for 'ccl=au:'John Snow, Inc./DELIVER. (who.int)

In Vienna March, 2016, UN officials created an Outcome Document to set international priorities for drug policy. (safeaccessnow.org)

In 2018, 23 states and DC had drug overdose death rates that were higher than the national rate of 20.7 per 100,000. (cdc.gov)

You'll find doses that purportedly mimic the effects of LSD, crack, heroin and other hard drugs. (flinn.org)
Over time, this process can be repeated, thus releasing doses of the enclosed drug at precisely controlled intervals. (mit.edu)
By understanding how the cancer drug is released and its effect on the cells and surrounding tissue, doctors can adjust doses to achieve the best result. (rdworldonline.com)

Clinics and pharmaceutical organizations in the Moscow, Leningrad, Novgorod, Kirov and Nizhny Novgorod regions, as well as in the Republic of Tatarstan and Ekaterinburg have already received the first deliveries of the drug. (pharmiweb.com)
The drug is in high demand across Russia, with negotiations underway to arrange deliveries to almost all regions of the country. (pharmiweb.com)
Roem later hired Cuong for many drug deliveries from Cambodia to HCMC via Hung Ha Commune in Long An. (vnexpress.net)

The initial results of clinical trials make this drug one of the most promising in the world. (pharmiweb.com)

The trials found that when other factors were taken into account, those given the drug lived 15 per cent longer than those who were not on it - which could mean an extra three years' lifespan for the average pensioner. (telegraph.co.uk)

Heroin is a drug used by millions around the world who know that if they stop, they face the horror of withdrawal. (drugfreeworld.org)

This is significant as it allows us to determine the kinetic movement of drug release in a true biological environment. (rdworldonline.com)
For more detailed information, see FDA's guidance titled Information Sheet Guidance For Sponsors, Clinical Investigators, and IRBs - Waiver of IRB Requirements for Drug and Biological Product Studies . (cdc.gov)

Regeneron's rare disease drug outshone placebo in a phase 2 study, warding off the majority of new bone formation in adults with a disorder that causes the body's soft tissues to turn into bone. (fiercebiotech.com)
The nanocarriers are designed so they're only taken up by cancer cells, thereby preventing the drugs from being absorbed by healthy tissues as they travel through the body's circulation. (innovationtoronto.com)
The hard part was finding materials that could be triggered to heat up by using a very weak magnetic field (about one-hundredth the strength of that used for MRI), in order to prevent damage to the drug or surrounding tissues, Rao says. (mit.edu)

Agencies will be asked to report things like when and where an overdose happened and the drugs involved. (kxan.com)

I feel like I have a lot of knowledge as to what drugs are, what they will do to your body and how they'll impact your life. (drugfreeworld.org)
I never really understood what drugs did to your body and actually how bad they are. (drugfreeworld.org)
What are the two body parts most affected by drug use? (bu.edu)

It was found to be releasing drug for long time and less toxic to RBC. (ssrn.com)

By way of background, Brazil is member to the 1996 International Agreement on Trade Related Aspects of Intellectual Property (TRIPS), a convention meant to boost respect for intellectual property rights in the pharmaceutical industry in a world of mass-produced generic drugs. (foreignpolicy.com)

I am in New York this week to take part at the United Nations General Assembly Special Session (UNGASS) where leaders from all over the world are joining together to discuss global drug policies, including what to do about medical Cannabis . (safeaccessnow.org)
With a shared commitment to moving global policy forward, ASA and IMCPC have created a 1-page document that ties cannabis into the international priorities for drug policy Outcome Document. (safeaccessnow.org)

When they lowered the pH of the surrounding solution, the fish opened its mouth to release a chemotherapy drug, which killed nearby cells. (acs.org)
Evanston police arrested a Chicago resident for possession of approximately $1,922 worth of drugs Friday afternoon, according to an Evanston Police Department news release. (dailynorthwestern.com)
This provides the ability to control the release of anticancer drugs by external stimuli. (spiritindia.com)
After insertion, the needles dissolve and release the drug. (mit.edu)
Chemical engineers and clinicians from University of New South Wales (UNSW) and Monash University have synthesized a new iron oxide nanoparticle that delivers cancer drugs to cells while simultaneously monitoring the drug release in real time. (rdworldonline.com)
Importantly, the multidisciplinary team led by Professor Tom Davis from Monash University, demonstrated for the first time the use of a technique called fluorescence lifetime imaging to monitor the drug release inside a line of lung cancer cells. (rdworldonline.com)
Usually, the drug release is determined using model experiments on the lab bench, but not in the cells," said Boyer. (rdworldonline.com)
Normal constriction and relaxation of GI tract muscles make it impossible for extended-release drugs to stay in the intestine long enough for the patient to receive the full dose," Selaru said in the release. (drugdeliverybusiness.com)

Trying idosers could indicate a willingness to experiment with drugs and other dangerous behavior. (flinn.org)

Using this peptide to deliver drugs means they could be administered intravenously, but still reach the site of injury in sufficient quantities to have an effect. (eurasiareview.com)
This may be as simple as needles and syringes, if the drugs are to be administered entirely intravenously. (medscape.com)

The fact that scientists are developing new drugs for the treatment of many grave diseases is a proof that medical technology has grown by leaps and bounds. (healthjockey.com)
Avifavir has also become the first Favipiravir-based drug in the world approved for treatment of COVID-19. (pharmiweb.com)
Information on demographic and socioeconomic characteristics, obstetric history, and drug treatment of women who delivered infants at sampled hospitals was obtained through an interviewer-administered questionnaire, while data on substance use before and during pregnancy were collected through a questionnaire completed by the respondent and concealed from the interviewer. (data.gov)
Anti-epileptic drugs are the main type of treatment for most people with epilepsy, aimed at preventing seizures from happening. (who.int)
The web posting clarifies that forms and other documentation required for obtaining TPOXX can be submitted after clinicians receive the drug and begin patient treatment. (cdc.gov)
Target 3.5: Strengthen the prevention and treatment of substance abuse, including narcotic drug abuse and harmful use of alcohol. (bvsalud.org)

Urine specimens collected routinely by the hospital on obstetric admissions were tested for selected drugs. (data.gov)
Routinely used medications have many potential interactions with drugs used during surgery, but few situations prohibit concurrent administration. (medscape.com)

Like many retail businesses, drug stores today are not immune to economic downturn, inflation and supply chain challenges. (drugstorenews.com)

Delivering drugs directly to cancer cells could help reduce these unpleasant symptoms. (acs.org)
The poor solubility of anticancer drugs is one of the major problems in cancer therapy because the drugs require the addition of solvents in order to be easily absorbed into cancer cells. (spiritindia.com)
Delivering drugs directly to cancer cells could help reduce the unpleasant side effects of chemotherapy. (technologynetworks.com)

Recently released WikiLeaks cables give us a behind the scenes look into how Brazil convinced international drug companies to sell their patented AIDS drugs at a low price: with a lot of pressure. (foreignpolicy.com)

Those efforts include a pill coated with many tiny needles , as well as star-shaped structures that unfold and can remain in the stomach from days to weeks while releasing drugs. (mit.edu)

Consolidated guidance can strengthen efforts of health-care providers and public health providers to prevent and treat infectious diseases and substance use and mental disorders, use resources efficiently, and improve health-care services and outcomes in persons who use drugs illicitly. (cdc.gov)

In the article, Dr. Naganna Nimishetti, Chief of the Small Molecule Drug Discovery Division (SMDD) and Dr. Dun Yang, CEO/CSO of Anticancer Bioscience, a precision therapeutics company headquartered in Chengdu, China, explain how the company is identifying bioactive hits using libraries of less than 100 compounds. (ddw-online.com)
Stay connected with all of the latest from Drug Discovery News. (drugdiscoverynews.com)

This report summarizes current (as of 2011) guidelines or recommendations published by multiple agencies of the U.S. Department of Health and Human Services (DHHS) for prevention and control of human immunodeficiency virus (HIV) infection, viral hepatitis, sexually transmitted diseases (STDs), and tuberculosis (TB) for persons who use drugs illicitly. (cdc.gov)

In this present study, SPIONs were synthesized by chemical co-precipitation method, loaded with itraconazole, a drug known to possess antibacterial and antifungal activities, encapsulated with microbial polymer (Polyhydroxybutyrate - PHB). (ssrn.com)
This is also especially relevant as most of the popular anticancer drugs possess serious side-effects due to unspecific action on healthy cells. (exposed-skin-care.net)

Current interventions for acute brain injury are aimed at stabilizing the patient by reducing intracranial pressure and maintaining blood flow, but there are no approved drugs to stop the cascade of events that cause secondary injury," said Aman Mann, Ph.D., postdoctoral researcher in Ruoslahti's lab and first author of the study. (eurasiareview.com)
But the UK study, led by Cardiff University, found that when patients with diabetes were given the drug metformin they in fact lived longer than others without the condition. (telegraph.co.uk)
The diabetics given metformin had far higher survival rates than those given the alternative drug, the study found. (telegraph.co.uk)
The purpose of this chapter is to describe the results of a randomized study (funded by the National Institute on Drug Abuse [NIDA]) comparing a peer-delivered enhanced intervention to the NIDA standard intervention for reducing human immunodeficiency virus (HIV) risk behaviors. (cdc.gov)
In this study, a simulation is also performed to list measures that theoretically should be in place to ensure the quality of the protein drug, for example validated and protocol-based compounding in cleanroom, training and validated transports. (lu.se)

I feel very lucky because now I know that drugs have a harmful effect on you. (drugfreeworld.org)

It could be a small jump from digital drugs to the real thing. (flinn.org)
Most drugs are absorbed through the small intestine, Traverso says, in part because of its extremely large surface area --- 250 square meters, or about the size of a tennis court. (mit.edu)
Drug stores also have a small window of opportunity to capture shoppers' attention when they are in the store or on the website compared to most other retail businesses. (drugstorenews.com)
Only a very small proportion of drugs reach the hypoxic zones, which are believed to be the source of metastasis. (innovationtoronto.com)

Research has also suggested that the diabetes drug shows some promise in slowing the spread of a number of cancers, including breast, lung, liver and prostate. (telegraph.co.uk)
Simon O'Neill, Director of Health Intelligence at charity Diabetes UK, said the research demonstrated that metformin should be the first choice drug for all patients with Type 2 diabetes. (telegraph.co.uk)

But there's one interesting clause in that agreement, allowing countries' governments to issue a 'compulsory license' for any drug they deem necessary to ward off a crisis situation. (foreignpolicy.com)

We hijacked it to deliver powerful cancer drugs into cells. (bostonmagazine.com)
One of the major bottlenecks in biotechnology is that there really doesn't exist a universal technology to deliver antibodies into cells," he says. (bostonmagazine.com)
They then launched gold nanoshells, with a peptide-lipid coating, that summarized 'silencing ribonucleic acid' (siRNA), which could be the drug that may be used by the cells. (healthjockey.com)
Among the backbones in nanomedicine is to deliver drugs specifically to unhealthy cells. (exposed-skin-care.net)

Nanoparticles18

Tumors8

Molecules5

Antiviral drug1

Researchers13

Antibody drugs2

World Health Organ2

Particles2

20194

Prescribe2

Proteins4

Therapeutic2

Inhalation2

Illicit3

Medicines8

Treatments5

Efficacy1

Delivery12

Allegedly2

Bioavailability2

Content1

20202

Potentially1

Uptake1

Monoclonal2

Epidemic1

Carriers2

Anthrax toxin1

Protein drugs2

Pharmacists1

Search1

20161

20181

Doses3

Deliveries3

Clinical trials1

Trials1

Heroin1

Biological2

Tissues3

Overdose1

Body3

Toxic1

Generic Drugs1

Cannabis2

Release8

Experiment1

Intravenously2

Treatment6

Routinely2

Supply chain1

Cancer cells3

AIDS1

Needles1

Outcomes1

Discovery2

Diseases1

Possess2

Study5

Harmful1

Small4

Research2

Ward1

Cells4