To study the relationship between the ACE insertion/deletion (I/D) polymorphism, blood pressure and risk of hypertension in current, former and non-smokers in a population-based cohort. (nih.gov)
Therefore, we investigated the possible association of ACE gene insertion/deletion (I/D) polymorphism and the severity of atherosclerosis, estimated on the basis of the number of coronary stenoses and critical arterial occlusions observed during coronary angiography. (degruyter.com)
The D allele of angiotensin I-converting enzyme gene insertion/deletion polymorphism is associated with the severity of atherosclerosis" Clinical Chemistry and Laboratory Medicine , vol. 46, no. 4, 2008, pp. 446-452. (degruyter.com)
Niemiec, P., Zak, I. and Wita, K. (2008) The D allele of angiotensin I-converting enzyme gene insertion/deletion polymorphism is associated with the severity of atherosclerosis. (degruyter.com)
The rs66698963 polymorphism, a 22 bp insertion-deletion within FADS2 , is associated with basal FADS1 expression, and coordinated induction of FADS1 and FADS2 in vitro . (biorxiv.org)
Mortality in patients with hypertension on angiotensin-I converting enzyme (ACE)-inhibitor treatment is influenced by the ACE insertion/deletion polymorphism. (ox.ac.uk)
Residual ACE activity during treatment, potentially modified by the ACE insertion/deletion (I/D) polymorphism, may explain part of this variability. (ox.ac.uk)
An insertion (I)/deletion (D) polymorphism in the angiotensin 1-converting enzyme (ACE) gene has, in some studies, been associated with increased risk for Alzheimer's disease (AD), and functionally the enzyme has been implicated in the degradation of amyloid beta protein (Abeta). (birmingham.ac.uk)
Several studies of critically ill patients have suggested an association of the D/D genotype of the insertion/deletion (I/D) angiotensin-converting enzyme (ACE) polymorphism with poor outcome probably by enhancing the inflammatory response and leading to a procoagulant state. (biomedcentral.com)
Angiotensin-converting enzyme gene insertion/deletion polymorphism and breast cancer risk. (cdc.gov)
Insertion/deletion polymorphism of the angiotensin I-converting enzyme gene in patients with breast cancer and effects on prognostic factors. (cdc.gov)
Renin-angiotensin system inhibitors, angiotensin I-converting enzyme gene insertion/deletion polymorphism, and cancer: the Rotterdam Study. (cdc.gov)
Association of angiotensin I converting enzyme insertion/deletion polymorphism with breast cancer: a meta-analysis. (cdc.gov)
The ACE insertion/deletion polymorphism and risk of cancer, a review and meta-analysis of the literature. (cdc.gov)
Substitutions6
Insertions and deletions (indels) account for more nucleotide differences between two related DNA sequences than substitutions do, and thus it is imperative to develop a method to reliably calculate the occurrence probabilities of sequence alignments via evolutionary processes on an entire sequence. (biomedcentral.com)
To automatically detect inappropriate insertions, deletions, and substitutions of words in radiology reports, we proposed using a neural sequence-to-sequence (seq2seq) model. (amegroups.org)
Insertions, substitutions, and deletions of words were randomly introduced. (amegroups.org)
Seq2seq models can be highly effective at detecting erroneous insertions, deletions, and substitutions of words in radiology reports. (amegroups.org)
The changes to the proteins can come in the form of amino acid substitutions, insertions, or deletions. (cdc.gov)
Insertions and deletions that have a length divisible by 3 cause amino acid insertions/deletions or block substitutions are called 3n changes. (lu.se)
Indels2
Other types of mutation signatures based on small insertions and deletions (indels) 9 and on structural variants 22 are also starting to be introduced. (nature.com)
Out of 70158 InDels, 2,426 (1032 Insertions and 1394 deletions) with ≥20 bp size among different parental lines were selected. (icrisat.org)
Indel4
Francisella tularensis, a potent human pathogen and a pu- needed, not only because of their use in clinical and public tative bioterrorist agent, we combined analysis of insertion- health work but also because of a rising concern associated deletion (indel) markers with multiple-locus variable-number with risks for bioterrorism ( 4 , 8 ). (cdc.gov)
Completely sequenced plant genomes provide scope for designing a large number of genome wide insertion-deletion (InDel) markers, which are useful in various aspects of crop breeding and genetic analysis. (icrisat.org)
A deletion-insertion (delins) variant may also be known as an insertion-deletion (indel) variant. (medlineplus.gov)
2013) SIFT Indel: Predictions for the Functional Effects of Amino Acid Insertions/Deletions in Proteins. (lu.se)
Genome2
The design of the T7.1 genome allows for the simple deletions of parts. (openwetware.org)
Overall, these assays and approaches detect specific mutations or features such as insertions, deletions and point mutations in the SARS CoV-2 genome that are characteristic of a particular VOC/VOI using PCR. (who.int)
Amino1
This deletion occurs in-frame, so presenilin protein is produced, but it lacks amino acids 290-319. (alzforum.org)
Substitution1
We investigate a promising coding scheme over channels impaired by insertion, deletion, and substitution errors, i.e., interleaved concatenation of an outer low-density parity-check (LDPC) code with error-correction capabilities and an inner marker code for synchronization purposes. (elsevierpure.com)
Gene3
Small deletions remove one or a few nucleotides within a gene, while larger deletions can remove an entire gene or several neighboring genes. (medlineplus.gov)
This variant occurs when a deletion and insertion happen at the same time in the same location in the gene. (medlineplus.gov)
This dataset contains 9710 3n neutral insertions and deletions identified from UCSC mammalian alignments, chosen so that there is one random insertion or deletion per gene. (lu.se)
Angiotensin3
We aimed to identify the relationship between adiposity and blood pressure, independent of a robust set of lifestyle and metabolic factors, and to examine the modulating role of sex and Angiotensin-Converting Enzyme (ACE) insertion/deletion (I/D) polymorphisms. (lu.se)
Association between the angiotensin-converting enzyme (insertion/deletion) and angiotensin II type 1 receptor (A1166C) polymorphisms and breast cancer among Brazilian women. (cdc.gov)
Association of angiotensin I converting enzyme (insertion/deletion) and angiotensin II type 1 receptor (A1166C) polymorphisms with breast cancer prognostic factors in Iranian population. (cdc.gov)
Sequence3
These circumstances make it imperative to develop a stochastic model that enables us to reliably calculate the probability of sequence evolution via mutations including insertions and deletions. (biomedcentral.com)
The methods used in multigene panels may include sequence analysis , deletion/duplication analysis , and/or other non-sequencing-based tests. (nih.gov)
insertion states appear as lowercase letters in the sequence. (cdc.gov)
Nucleotide2
In a deletion-insertion variant, at least one nucleotide is removed and at least one nucleotide is inserted. (medlineplus.gov)
This process helps identify single or multiple nucleotide variations as well as areas of insertion or deletion. (msdmanuals.com)
Variants3
Insertions, deletions, and duplications can all be frameshift variants. (medlineplus.gov)
150bp) such that variants containing deletions or separations of the individual elements could be easily constructed (e.g., the E. coli promoter C and RNaseIII site R1). (openwetware.org)
The positive (disease-causing) insertion and deletion dataset consists of 9007 variants, 2667 frameshift (FS) insertions and deletions and 6340 non frame-shift (NFS) insertions and deletions. (lu.se)
Proteins1
A comprehensive study of small non-frameshift insertions/deletions in proteins and prediction of their phenotypic effects by a machine learning method (KD4i). (lu.se)
Allele1
Our study is consistent with previous in vitro data suggesting that the insertion allele enhances n-6 LCPUFA synthesis and may confer an adaptive advantage in South Asians because of the traditional plant-based diet practice. (biorxiv.org)
Frameshift1
The pathogenic dataset contains 6513 frameshift (FS) and 5023 non frameshift (NFS) insertions and deletions from ClinVar database. (lu.se)
Intron1
This point mutation at a splice site in intron 8 was the first mutation in PSEN1 determined to result in the deletion of exon 9 from mRNA transcripts. (alzforum.org)
Dataset2
The neutral dataset contains 8861 micro-insertions and deletions from the 1,000 Genomes Project (20101123 release). (lu.se)
Dataset for training predictor for frameshifting insertions and deletions. (lu.se)
Protein1
The authors also presented relatively high levels of disagreement in variant detection calls, especially for insertion/deletions in protein coding regions and those that could be related to disease. (cdc.gov)
Modification3
Theoretical and experimental results demonstrate that the proposed technique is resilient against tuples insertion, tuples deletion, and attributes values modification attacks. (hindawi.com)
Benign update may cause the modification or deletion of marked tuples. (hindawi.com)
Update - Insertion, modification, and deletion of the actual data. (wikipedia.org)
Nodes1
We used a very aggressive deletion policy - deleting nodes with three minutes of unused time. (ibm.com)
Probability1
The bottom plot gives the probability that there is an insertion (light green) or a deletion (red) at that position in the HMM. (cam.ac.uk)
Alignment2
Fig. 2: Improved alignment by NGMLR for a 228-bp deletion and a 150-bp inversion. (nature.com)
Insertions are removed from the amended global alignment. (cdc.gov)
Point1
Then one of those cells mutates through a DNA insertion, deletion, or point mutation, and suddenly a new pattern appears. (cdc.gov)
File1
The SAM file is processed and deleted regions spanned by reads are restored to deletions. (cdc.gov)
Expected length1
assuming there is an insertion at that node, 1/(1-P) gives its expected length. (cam.ac.uk)
Cases1
Cotton-wool plaques also were noted in two additional cases with exon 9 deletion who had died at age 52 and 59, respectively. (alzforum.org)
Tree3
In AVL trees, we keep a check on the height of the tree during insertion operation. (guru99.com)
After every insertion, we balance the height of the tree. (guru99.com)
Insert the node in the AVL tree using the same insertion algorithm of BST. (guru99.com)
Regions3
Amplicon dropouts can sometimes leave zero coverage regions where no in-read deletions were detected. (cdc.gov)
It can be useful to differentiate these regions from deletions in the amended consensus. (cdc.gov)
Regions still containing the mask have zero coverage and are not necessarily due to deletion events. (cdc.gov)
Operation1
Most simply, if there is a pre-existing restriction site due to a deletion operation, then we can insert a new part in its place. (openwetware.org)