A number of bacteria that can degrade a variety of aromatic compounds have been identified and the pathways involved in the degradation have been extensively characterized [ 3 , 4 ]. (biomedcentral.com)
Based on the complexity of the degradation pathways, the phenomenon of biodegradation is categorized into two types: convergent and divergent modes of degradation (Fig. 1 ). (biomedcentral.com)
Further, the centralized degradation pathways mean synthesis of fewer degradative enzymes requiring less metabolic energy. (biomedcentral.com)
However, the microbial metabolic pathway of the fungicide and the genetic systems driving its degradation by strain P3 remain unknown. (nature.com)
Comparative genome analysis showed that strain MC4 harbors the complete pathway (lin genes) required for HCH degradation. (bvsalud.org)
The hydrolysis-, hydroxylated-, monoglucosylated-, methylated products and glutathione (GSH) conjugated derivative were identified and new degradation pathway of TPHP mediated by microorganism was proposed. (bvsalud.org)
Ortho2
In this divergent mode, a metal-dependent dioxygenase channels these dihydroxylated intermediates into one of the two possible pathways: the meta -cleavage pathway or the ortho -cleavage pathway [ 7 - 9 ] (Fig. 1 ). (biomedcentral.com)
Genomic analysis identified two orthologous operons encoding the ortho -cleavage of benzoic acid (BA) ( ben/cat ). (nature.com)
Metabolic3
Therefore, elucidation of the microbial metabolic pathway of OPP is a prerequisite for the downstream exploitation of strain P3 in any environmental application. (nature.com)
6 identified a gene cluster, hbpCAD , encoding the upper metabolic pathway of OPP which involves the transformation of OPP to 2-hydroxypenta-2,4-dienoateand benzoic acid (BA). (nature.com)
The downstream transformation of BA involved a meta -cleavage pathway, although its genetic organization and function was not revealed and the overall network of genes driving the full metabolic pathway of OPP is still not known. (nature.com)
Cell1
The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
Catabolic pathways3
Degradation of the two isomeric compounds proceeds via separately inducible catabolic pathways that converge at protocatechuate. (nih.gov)
Analysis of the catabolic pathways by which these two isomers are degraded demonstrated that a cis-dihydrodiol intermediate is involved in both pathways. (nih.gov)
Given that a large number of aromatic compounds are formed by organisms, for example, aromatic amino acids, phenols, or quinines, it is not surprising that many microorganisms have evolved catabolic pathways to degrade them. (europa.eu)
Microorganisms1
In one set of studies, the ability of plants to foster degradative microorganisms was investigated. (nih.gov)
Fate1
The advancement of cancer in guy involves numerous genetic alterations that normally bring about dysfunction of specific signaling pathways controlling cell fate, cell development, and cell survival or cell death. (gabapathway.com)
Oxidation2
Photosynthesis was unaffected by glyphosate in RRS leaves, but decreased abundance of photosynthesis/photorespiratory pathway proteins was observed together with oxidation of major redox pools. (ban-glyphosate.com)
Conversely, the accumulation of high levels of glyphosate in RRS enhances cellular oxidation, possibly through mechanisms involving stimulation of the photorespiratory pathway. (ban-glyphosate.com)
Activation1
The protective impact of PGRN on this may be associated with the early activation of the PI3K/Akt signaling pathway. (biomedcentral.com)