Defects of the knee. Medical search. Frequent questions

Stem cell therapy is now used to treat knee injuries, focal cartilage defects, knee osteoarthritis and other knee pain and problem. (tarlowknee.com)
The significance of asymptomatic knee cartilage defects in healthy individuals is not known. (edu.au)
The aim of this study was to examine the association between cartilage defects in the knee and cartilage volume both cross-sectionally and longitudinally in healthy, middle-age adults. (edu.au)
Cartilage defects were scored according to a grading system (0-4) and as present (a defect score of â‰¥2) or absent in the medial and lateral tibiofemoral compartments. (edu.au)
Cartilage defects in the medial and lateral tibiofemoral compartments were very common (in 61% and 43% of subjects, respectively). (edu.au)
Those with cartilage defects had a 25% reduction in medial tibial cartilage volume, a 15% reduction in lateral tibial cartilage volume, and a 19% reduction in total femoral cartilage volume relative to those with no cartilage defects in cross-sectional analyses (all P (edu.au)
In the medial tibiofemoral compartment, the annual loss of tibial cartilage in those with cartilage defects was 2.5% (95% confidence interval [95% CI] 2.2%, 3.1%) compared with an annual loss of tibial cartilage of 1.3% (95% CI 0.5%, 2.0%) in those with no defects (P = 0.028), independent of other known risk factors for osteoarthritis (OA). (edu.au)
These data suggest that the presence of asymptomatic, non-full-thickness medial tibiofemoral cartilage defects identifies healthy individuals most likely to lose knee cartilage in the absence of radiographic knee OA. (edu.au)
Thus, interventions aimed at reducing or reversing cartilage defects may reduce the risk of subsequent knee OA. (edu.au)
Specifically, larger, full-thickness cartilage defects remain a challenge. (matthewprovenchermd.com)
For cases of cartilage defects that are larger than 10mm in size, the BioUni knee transplantation of fresh cartilage (through a bone and cartilage transplant) is an excellent option to restore these defects. (matthewprovenchermd.com)
This is my technique for biologic unicompartmental osteochondral allograft transplantation for the treatment of large femoral condyle articular cartilage defects. (matthewprovenchermd.com)
Effective treatment of cartilage defects represents a challenging problem, mainly due to the tissue's limited intrinsic self-repair capacity. (nature.com)
Currently, the only FDA-approved cell-based therapy for cartilage defects involves autologous chondrocyte implantation: chondrocytes harvested from low-contact areas are expanded in vitro and then re-injected directly into the damaged site 1 . (nature.com)
Nasal chondrocyte-based engineered autologous cartilage tissue for repair of articular cartilage defects: an observational. (thenakedscientists.com)
Her second research area focuses on the neuromuscular, biomechanical and functional outcomes of individuals with varying degrees of knee joint degeneration, from those with focal articular cartilage defects to end-stage knee osteoarthritis and total knee arthroplasty. (osu.edu)
Muscle co-contraction during gait in individuals with articular cartilage defects in the knee. (osu.edu)

He spoke with sources who suggested Jack has a chondral defect in his knee. (ninersnation.com)
Dug a little -- Per sources, issue for UCLA LB Myles Jack is a chondral defect in his right knee. (ninersnation.com)
According to NFL Network's Albert Breer, Jack has a chondral defect in his knee. (campussports.net)
When the articular cartilage (the cartilage lining the end of the bones)has been injured or damaged, it's referred to as a chondral defect. (manhattansportsdoc.com)

The use of autogenous bone graft is a well-known technique for reconstruction of tibial bone defects in primary total knee arthroplasty (TKA). (biomedcentral.com)
A severe tibial bone defect in primary total knee arthroplasty (TKA) is one of the biggest challenges to treat for the surgeon, which can lead to a poorly balanced tibial component. (biomedcentral.com)
Bone Graft for Tibial Defects in Total Knee Arthroplasty. (fatcat.wiki)
Dr. Wheeless enjoys and performs all types of orthopaedic surgery but is renowned for his expertise in total joint arthroplasty (Hip and Knee replacement) as well as complex joint infections. (wheelessonline.com)
A common procedure that may require reconstructive surgery to achieve adequate soft tissue coverage of the knee is total knee arthroplasty (TKA). (medscape.com)
Often, patients who require a knee replacement have insensate and unstable skin around the knee joint secondary to trauma, post-knee arthroplasty wound breakdown, or persistent synovial fistula following an arthroscopy. (medscape.com)

CTGF/CCN2, a hypertrophic chondrocyte-specific gene product, possessed the ability to repair damaged articular cartilage in two animal models, which were experimental osteoarthritis and full-thickness defects of articular cartilage. (elsevierpure.com)
Materials and Methods: The effects of recombinant CTGF/CCN2 (rCTGF/CCN2) on repair of damaged cartilage were evaluated by using both the monoiodoacetic acid (MIA)-induced experimental rat osteoarthritis (OA) model and full-thickness defects of rat articular cartilage in vivo. (elsevierpure.com)
Most osteoarthritis (OA) resulting from degenerative diseases of joints, traumas and inflammation will unavoidably progress to osteochondral defects ( 1 ). (spandidos-publications.com)
Effect of Autologous Conditioned Plasma Injections in Patients With Knee Osteoarthritis. (mayo.edu)
The Fusion® Women's OA Plus knee brace provides medial compartment off-loading for patients with unicompartmental osteoarthritis. (breg.com)
The second objective of this study is to identify factors, early after ACL reconstruction, which may predispose individuals to articular cartilage degeneration and the early development of knee osteoarthritis. (osu.edu)

Next, to examine the effect of rCTGF/CCN2 on the repair of articular cartilage, we created defects (2 mm in diameter) on the surface of articular cartilage in situ and implanted rCTGF/CCN2-hydrogel or PBS-hydrogel therein with collagen sponge. (elsevierpure.com)

Moreover, an uncontained defect is associated with a resultant angular deformity that is usually posterior and medial in a more than 20° varus knee from primary TKA [ 1 ]. (biomedcentral.com)

Birth defects - also known as congenital anomalies - are a leading cause of infant death that account for more than 1 of every 5 infant deaths . (cdc.gov)
Though research has yielded mixed results about SNRIs and birth defects in children, many women like Amanda Hatherley have pursued an Effexor lawsuit after giving birth to a child with life-threatening congenital birth defects. (injurylawyer-news.com)
She required extended hospitalization and underwent a battery of tests before being diagnosed with congenital kidney defects and reflux . (injurylawyer-news.com)
These defects may arise as a result of traumatic injuries, tumor surgery, or congenital defects. (uthscsa.edu)

Various surgical options are available, including a thicker tibial bone resection, filling in the defect with methylmethacrylate cement, alone or with screws, and the use of metal augments [ 2 , 3 ]. (biomedcentral.com)

Stem cells are now used as an alternative to traditional options like total knee joint replacement and arthroscopic knee surgery . (tarlowknee.com)
He performs the full spectrum of Knee Surgery from Knee Arthroscopy, ACL Reconstruction, Patellar Stabilization and Cartilage Restoration to Makoplasty Partial Knee Replacement to Total Knee Replacement to Revision Total Knee Replacement. (tarlowknee.com)
In Australia, follow-up with patients receiving total knee replacements with the OPTETRAK system showed a significantly higher revision rate when compared to other companies' total knee replacement systems. (burgsimpson.com)

The management of bone defects on the tibial aspect can vary depending on the size and location of the loss of bone, and it is necessary to consider other patient specific factors such as age, functional requirements, and bone quality. (biomedcentral.com)

Aside from stem cell therapy, there are other surgical treatments using autologous stem cells and a biologic scaffold (hylofast) that is implanted directly into focal chondral lesions of the knee. (tarlowknee.com)

One problem that former UCLA linebacker Myles Jack has been facing over the last few weeks is the status of his knee that he had operated during the 2015 season. (campussports.net)

Defects of both tibiofemoral and patellofemoral joints were included. (springer.com)
The typical pathognomic appearance of an uncomplicated osteochondroma on knee radiographs consists of an osseous excrescence with medullary and cortical continuity near the metaphysis that points away from the tibiofemoral joint. (appliedradiology.com)

The symptoms of articular cartilage damage include joint pain, swelling, stiffness and a decrease in the range of motion of the knee. (drsathu.com.au)
Dr. Benedict Nwachukwu specializes in a variety of hip conditions including chondral defects of the hip and articular cartilage damage. (manhattansportsdoc.com)

Major birth defects are conditions present at birth that cause structural changes in one or more parts of the body. (cdc.gov)
Spina bifida is a major birth defect of a person's spine and Anencephaly is a serious birth defect in which a baby is born without parts of the brain and skull. (cdc.gov)
Using updated birth certificate data available for the U.S. since 1989 , NCHS followed a 16-year trend from 1991 to 2006 for the two neural tube defects. (cdc.gov)
For more information on birth defects, please click here . (cdc.gov)
The Wonderful World of Greens Green vegetables can strengthen bones, sharpen your vision, even prevent birth defects. (nxtbook.com)
California resident Amanda Hatherley filed an Effexor lawsuit against Pfizer and McKesson in the Shasta County California Superior Court, based on allegations that her newborn child died as direct result of birth defects caused by her use of the antidepressant during pregnancy. (injurylawyer-news.com)
However, on July 3, 2013, Judge William Shub remanded the Effexor birth defects case to state court , finding defendant McKesson Corp. was not falsely joined in the action because the company is not protected from liability for failure to warn of the medication's risks. (injurylawyer-news.com)
Plaintiffs are suing Pfizer, claiming the drug manufacturer is liable for failing to warn about potential birth defects from Effexor when taken during pregnancy . (injurylawyer-news.com)
The case, which is proceeding in the U.S. District Court for the District of Delaware, is a little unusual compared to other Zofran lawsuits in that the parents claim that Zofran was responsible for the death of one daughter and the birth defects of another. (injurylawyer-news.com)
The plaintiffs claim that Zofran was directly responsible for the death of their first daughter and the birth defects of their second child. (injurylawyer-news.com)
During pregnancy there are screening tests (prenatal tests) to check for spina bifida and other birth defects. (cdc.gov)

For more information on how folic acid helps prevent neural tube defects click here . (cdc.gov)
An AFP test might be part of a test called the "quad screen" that looks for neural tube defects and other issues. (cdc.gov)

It features Breg's exclusive adjustable hinge technology, which provides an effective valgus load to the knee. (breg.com)

The skull (cranium), hip (iliac crest), and lateral knee (tibia), are common donor sites. (uthscsa.edu)

Believers of stem cell treatment say people with knee injuries are good candidates for such treatment. (tarlowknee.com)
In theory, stem cells are beneficial to knee injuries and arthritis. (tarlowknee.com)
Differences in Trampoline-Related Knee Injuries Between Children and Adults: A Cross-Sectional Study. (mayo.edu)
While prior results are not a guarantee of future outcomes, prior knee replacement settlements have ranged between $50,000 and $500,000, with some substantially larger knee lawsuit payouts involving extraordinary injuries. (youhavealawyer.com)
Burg Simpson is investigating claims on behalf of individuals who sustained serious injuries as a result of Exactech knee replacements, ankle replacements, and hip replacements. (burgsimpson.com)
If you or a loved one has suffered injuries and required revision surgery due to a dangerous medical device such as the OPTETRAK Knee System, OPTETRAK Logic Knee System, TRULIANT Knee System, or VANTAGE Total Ankle System, call us today at 888-895-2080 . (burgsimpson.com)
An expert in shoulder, knee, and other sports injuries, he is widely known as one of the country's best orthopedic surgeons. (howardluksmd.com)
Patients with knee injuries have been treated using cartilage grown from their own noses, Swiss doctors announced this week. (thenakedscientists.com)
With this in mind, Basel University's Ivan Martin and his colleagues recruited ten patients with cartilage injuries to their knees. (thenakedscientists.com)
[ 2 ] In burn injuries of the knee, contractures left untreated for prolonged periods result in permanent shortening of the flexor tendons, nerves, and vessels. (medscape.com)

This systematic review updated the current evidence on MSCs augmentation for chondral procedures in patients with symptomatic chondral defects of the knee. (springer.com)
All the clinical studies investigating surgical procedures for chondral defects of the knee augmented with MSCs were accessed. (springer.com)
Thus, this systematic review updated the current evidence on MSCs application in chondral defects of the knee. (springer.com)
Mobilized pluripotent MSCs from the subchondral bone migrate into the defect filled with the clot, differentiate into chondrocytes and osteoblasts, and form a repair tissue over time. (hindawi.com)
They were first isolated from the bone marrow, and the potency of MSCs is currently being employed in the techniques of marrow stimulation for symptomatic small chondral defects. (hindawi.com)

Chondral lesions of the knee can affect the young, active population, thereby causing severe morbidity and loss of function pain and swelling. (matthewprovenchermd.com)
Orthopedic intervention is indicated for rapidly progressive scoliosis and for some severe bony defects. (medscape.com)
Problems with a knee implant can cause severe pain, loss of mobility, long-term disability, diminished overall quality of life and additional medical expenses. (youhavealawyer.com)

We describe a simple and reliable technique of reconstruction in a proximal tibia bone defect at the time of primary TKA by using autogenous onlay bone graft (AOBG). (biomedcentral.com)
Dr. Tarlow is the only Orthopedic Surgeon to limit his practice to encompass Adult Reconstruction and Sports Medicine for the diagnosis and treatment of knees. (tarlowknee.com)
The application of L‑PRF and F‑PRF for osteochondral defects in rabbits contributed to massive host remodeling and reconstruction of osteochondral tissues, thus offering a prospective bioactive scaffold for the simultaneous reconstruction of articular cartilage and subchondral bone tissue. (spandidos-publications.com)
Altered Knee Mechanics during Landing at the Time of Return to Sport following Anterior Cruciate Ligament Reconstruction: Effects of Quadriceps Strength Asymmetry. (osu.edu)
Young Athletes after ACL Reconstruction with Asymmetric Single-Leg Drop-Landing Mechanics at the Time of Return-to-Sport Demonstrate Worse Knee Function Two Years Later. (osu.edu)

Release of the contracture leaves large skin defects and exposes bow-stringed hamstring tendons and major vessels and nerves in the popliteal fossa, requiring soft tissue coverage. (medscape.com)

Osteochondral defects caused by degenerative diseases of joints, traumas and inflammation are important issues in clinical practice. (spandidos-publications.com)
Learning to walk with the prosthesis, rehabilitating muscles and joints that often have not been used normally for many months is critical for a successful result, following a below-knee amputation. (footeducation.com)
Chronic overuse of the lower extremity in young athletes can cause OCD at the knee and ankle joints. (medscape.com)

At 16 weeks after implantation surgery, full‑thickness osteochondral defects with a diameter of 5 mm and a depth of 4 mm were well‑filled with newly regenerated tissues, exhibiting the simultaneous regeneration of avascular articular cartilage and well‑vascularized subchondral bone, as proven through macroscopic and microscopic observations in PRF‑treated groups compared with that in the untreated group. (spandidos-publications.com)

In addition to demanding compensatory damages in the Zofran heart defect lawsuit, the plaintiffs demand that the makers of Zofran be ordered to remove the pregnancy category B designation from the product label. (injurylawyer-news.com)

In overcoming these disadvantages, we describe a simple and reliable technique to reconstruct bone defects of the proximal tibia at the time of primary TKA by using autogenous onlay bone graft (AOBG) to ensure higher graft healing rates and lower infection rate without the use of an additional allogenous bone or metal augments. (biomedcentral.com)
The particular nature of hyaline articular cartilage, including the avascular nature and the low number of chondrocytes and stem cells in the surrounding cartilage lesions, results in limited potential to reconstruct osteochondral defects through a self-healing process ( 1 , 2 ). (spandidos-publications.com)

The articular or hyaline cartilage is the tissue lining the surface of the two bones in the knee joint. (drsathu.com.au)
Damasena I, Spalding T. Computed tomography of the knee joint: indications and significance. (medlineplus.gov)
25 34 38 42 49 53 Knee-to-Know Basics This joint keeps you jumping-and walking, climbing and moving. (nxtbook.com)
In both the hip and the knee, removal and replacement of the PE liner are frequently necessary to provide access to the complete joint for thorough débridement, and this is the reason why arthroscopic débridement has fallen into disfavor in the knee. (medscape.com)
The knee joint has the largest articular space. (wikidoc.org)
The knee joint supports two to five times a person's body weight depending on the physical activity . (wikidoc.org)
The procedure is performed in order to preserve the function of the knee joint, so the remaining stump must be long enough to fit a prosthesis, and to provide adequate soft-tissue padding over what would otherwise be a prominent stump of bone. (footeducation.com)
Under local anaesthetic, and using standard knee operating techniques, the patches were implanted into the damaged knee joint, "butter side down" so that the new cells were in contact with the underlying bone at the injury site. (thenakedscientists.com)
Early aseptic closure is of paramount importance to the preservation of the function of the knee joint. (medscape.com)
For excellent patient education resources, visit eMedicineHealth's patient education article Knee Joint Replacement . (medscape.com)
We recently evaluated an adolescent female soccer player who had involvement of OCD in both knees, both elbows, and the right first metatarsophalangeal (MP) joint. (medscape.com)

Radiograph (antero-posterior view) of our patient's left knee and leg, taken one year after surgery, showing the proximal tibia fracture united. (biomedcentral.com)

ACI is a two-step surgical procedure which necessitates chondral harvesting from a non-weight-bearing area of the knee and external chondrocytes expansion in a dedicated laboratory [ 9 , 10 ]. (springer.com)

At follow-up evaluation, the patients were assessed clinically using Knee Society score (KSS) and range of motion (ROM). (biomedcentral.com)
Knee radiographs are ubiquitous studies interpreted by many radiologists in daily clinical practice, since X-ray is the most appropriate imaging modality for initial evaluation of nearly all knee signs and symptoms. (appliedradiology.com)
Thereafter, these bioactive scaffolds were implanted into osteochondral defects surgically created in rabbits to assess their effects on tissue repair using micro‑CT scanning, histological observations and the evaluation scoring method for cartilage repair established by the International Cartilage Repair Society (ICRS). (spandidos-publications.com)
Request a free consultation and knee replacement lawsuit evaluation. (youhavealawyer.com)

Dr. Tarlow's practice focuses on excelling in the art of Knee Diagnosis and Surgery. (tarlowknee.com)
Biomaterials for meniscus and cartilage in knee surgery: state of the art. (mayo.edu)
Compensation may be available to pay for revision surgery and other costs associated with malfunctioning Exactech knee, ankle, and hip replacement devices. (burgsimpson.com)
Soft tissue defects of the knee that require reconstructive surgery occur after trauma or following a surgical procedure. (medscape.com)

This therapy works by adding new cells to the defected, diseased or damaged knee. (tarlowknee.com)

Stem cell therapy is a modern and novel procedure which is used to treat certain orthopedic knee )conditions and diseases. (tarlowknee.com)

It is not indicated for advanced arthritis of the knee. (drsathu.com.au)
If you're interested in seeking treatment for your knee arthritis , please make an appointment with my office so we can talk about the best scientifically validated treatments out there. (tarlowknee.com)

Keratosis also affects other sites such as elbows and knees. (lu.se)
She had a history of 4 operations, 1 each at both knees and both elbows, for the treatment of osteochondritis dissecans (OCD). (medscape.com)

The bone is either obtained from a tissue bank or your own bone is taken from the jaw, hip or tibia (below the knee). (uthscsa.edu)

However, if you know for sure that you have an Exactech Optetrak or Truliant implant, review our Exactech knee lawsuit page for more information. (youhavealawyer.com)
The average settlement amount or knee replacement lawsuit payout can vary greatly depending on the extent of problems caused by the defective implant. (youhavealawyer.com)
Parents from Texas recently filed a lawsuit against the makers of Zofran, claiming that the drug caused heart defects . (injurylawyer-news.com)
She had an ultrasound exam, which the lawsuit reports did not show signs of heart defects or any other abnormalities. (injurylawyer-news.com)

The approach to the diagnosis of knee pain is based on a step-wise testing strategy. (wikidoc.org)
Below is an algorithm summarizing the identification and laboratory diagnosis of knee pain . (wikidoc.org)

9,10,12 Although signs of periosteal osteosarcoma may appear subtle on knee radiographs, magnetic resonance imaging (MRI) typically reveals a large, extraosseous soft-tissue mass with intramedullary invasion in some cases. (appliedradiology.com)
Another cause of soft tissue deficit results from the release of burn contractures involving the knee. (medscape.com)

Diagnostic arthroscopy confirmed the presence of OCD, and treatment included arthrotomy, excision of the loose body, and microfracture of the defect. (medscape.com)

The present study included 19 patients (10 women and 9 men) with a hip-knee-ankle (HKA) of 20° or more on preoperative long-standing anteroposterior radiographs (Fig. 1 ). (biomedcentral.com)
These Exactech knee and ankle replacements have plastic components made of Ultra High Molecular Weight Polyethylene (UHWMPE). (burgsimpson.com)
Over time, oxidation can damage the structural integrity and mechanical properties of the plastic components of these knee and ankle devices. (burgsimpson.com)

In the group implanted with rCTGF/CCN2-hydrogel collagen, new cartilage filled the defect 4 weeks postoperatively. (elsevierpure.com)

This simple AOBG supplement technique may biologically promote graft to host bone healing by enhancing fixation stability without the additional fixatives and assist the surgeon in managing the varying nature of uncontained bone defects. (biomedcentral.com)
Knee Surgeon and Specialist Stefan D. Tarlow, M.D. (tarlowknee.com)

Diabetic foot infection, ulcers due to poor blood supply, bone infections, etc) where a below-the-knee amputation is not only warranted, but offers the patient the best chance for a more functional, more timely, and often less painful extremity. (footeducation.com)

Large defects are repaired using the patient's own bone. (uthscsa.edu)

However, there is little basic science to support its use as an injection to the knee in 2017. (tarlowknee.com)

Recovery from a below knee amputation involves wound healing, rehabilitation, and emotional support. (footeducation.com)
Swelling is very common following a below knee amputation, and can last several months. (footeducation.com)
Previously, recommended management has been implant removal followed by arthrodesis and, at times, has required above-knee amputation (AKA). (medscape.com)
The salvage of the knee in this patient allows for greatly improved function over an above-the-knee amputation. (medscape.com)

Internal Fixation of Unstable Osteochondritis Dissecans of the Knee: Long-term Outcomes in Skeletally Immature and Mature Patients. (mayo.edu)

Penetrating trauma or surgical wounds both put the knee at risk of exposure. (medscape.com)
Prostheses in the knee are particularly at risk because of their superficial location and the location of the surgical access wounds. (medscape.com)

Our findings confirm the safety and feasibility of cartilage grafts engineered from nasal cells to repair damaged knee cartilage. (thenakedscientists.com)
Major bone grafts are typically performed to repair defects of the jaws. (uthscsa.edu)

Anatomy34

Organisms7

Diseases51

Chemicals and Drugs13

Analytical, Diagnostic and Therapeutic Techniques and Equipment68

Psychiatry and Psychology3

Phenomena and Processes33

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture4

Humanities1

Information Science6

Named Groups1

Health Care23

Cartilage defects17

Chondral defect4

Arthroplasty6

Osteoarthritis6

Repair of articular cartilage1

Medial1

Congenital4

Methylmethacrylate cement1

Total knee3

Management of bone1

Autologous1

Myles Jack1

Tibiofemoral2

Articular cartilage damage2

Birth11

Neural tube de2

Valgus1

Lateral1

Injuries10

MSCs5

Severe3

Reconstruction5

Skin defects1

Joints3

Full-thickness1

Plaintiffs1

Reconstruct2

Joint11

Proximal1

Chondrocytes1

Evaluation4

Surgery4

Diseased or damaged1

Procedure1

Arthritis2

Elbows2

Tibia1

Lawsuit4

Diagnosis2

Soft tissue2

Microfracture1

Ankle3

Postoperatively1

Surgeon2

Functional1

Patient's1

20171

Amputation4

Osteochondritis Dissecans1

Surgical2

Grafts2