ApoptosisApoptosis Regulatory ProteinsCaspasesCaspase 3Proto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsDNA FragmentationIn Situ Nick-End Labelingbcl-2-Associated X ProteinX-Linked Inhibitor of Apoptosis ProteinCell Line, TumorCell SurvivalSignal TransductionApoptosis Inducing FactorCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9Caspase InhibitorsMitochondriaCells, CulturedCaspase 8Tumor Suppressor Protein p53Fas Ligand ProteinEnzyme ActivationTumor Cells, CulturedCytochromes cbcl-X ProteinCell ProliferationCell LineBlotting, WesternMutationAnnexin A5Cell CycleFlow CytometryProto-Oncogene ProteinsAmino Acid Chloromethyl KetonesCysteine Proteinase InhibitorsAntineoplastic AgentsPoly(ADP-ribose) PolymerasesCell DivisionTransfectionEnzyme InhibitorsReactive Oxygen SpeciesHeart Septal Defects, VentricularRNA, Small InterferingMice, KnockoutTNF-Related Apoptosis-Inducing LigandJurkat CellsHeart Defects, CongenitalDown-RegulationMice, Inbred C57BLRNA, MessengerTime FactorsCell DeathPhosphorylationDose-Response Relationship, DrugCaspase 7HL-60 CellsHeart Septal Defects, AtrialMembrane Potential, MitochondrialMembrane GlycoproteinsTumor Necrosis Factor-alphaDNA DamageMolecular Sequence DataGenes, bcl-2Reverse Transcriptase Polymerase Chain ReactionUp-RegulationNecrosisCarrier Proteinsbcl-2 Homologous Antagonist-Killer ProteinCytochrome c GroupProto-Oncogene Proteins c-aktNF-kappa BProtein-Serine-Threonine KinasesMembrane ProteinsMyeloid Cell Leukemia Sequence 1 ProteinDNA-Binding ProteinsBH3 Interacting Domain Death Agonist ProteinImmunohistochemistryGene Expression RegulationStaurosporinePhenotypeHeLa CellsGene Expression Regulation, NeoplasticRNA InterferenceGene ExpressionTranscription Factorsbcl-Associated Death ProteinCeramidesOxidative StressModels, BiologicalMice, TransgenicFibroblastsAntineoplastic Agents, PhytogenicAmino Acid SequenceNeoplasm ProteinsReceptors, TNF-Related Apoptosis-Inducing LigandCell DifferentiationBase SequenceDrug SynergismCaspase 2