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  • bromide
  • The pH dependance on extraction efficiency for gallamine triethiodide and decamethonium bromide, bromophenol blue ion pairs was also evaluated. (oregonstate.edu)
  • Confirming the findings of Barlow, Ing, Paton and Zaimis, decamethylene- 1, 10-bis-trimethylammonium bromide (C 10) 'Syncurine' brand decamethonium bromide injection, has been found to have a curare-like activity exceeding that of d-tubocurarine chloride, the potency varying with the species and the method of test. (aspetjournals.org)
  • ammonium
  • Derivatives of ammonium compounds, NH4+ Y-, in which all four of the hydrogens bonded to nitrogen have been replaced with hydrocarbyl groups. (drugbank.ca)
  • Using a similar approach, we interconnected varying quaternary ammonium moieties with a lipophilic linker to provide N,N'-bis-nicotinium analogs, affording a lead compound, N,N'-dodecyl-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), which inhibited nicotine-evoked DA release and decreased nicotine self-administration. (uky.edu)
  • A method for removing perchlorate or other anionic contaminates from ground water which comprises the step of passing the ground water over activated carbon, wherein the activated carbon has been either preloaded with an organic cation functional group or organic cation polymer or cationic monomer, or tailored with ammonium or other reduced nitrogen-containing compound. (google.com)
  • Neuromuscular
  • The possibility of these phenomena should be considered if aminoglycosides are administered by any route, especially in patients receiving anesthetics, neuromuscular blocking agents such as tubocurarine, succinylcholine, decamethonium, or in patients receiving massive transfusions of citrate-anticoagulated blood. (drugs.com)
  • hydroxy
  • One compound from the same series, when substituted with a hydroxy group at C-3 in ring A and 2-thienyl moiety as ring B, showed greater activity against butyrylcholinesterase than to acetylcholinesterase. (biomedcentral.com)
  • The involvement of one catalytic triad residue (His438) of butyrylcholinesterase with the 3'-hydroxy group on ring A increases the selectivity of Compound A. C-C bond rotation around ring A also stabilizes and enhances the interaction of Compound A with butyrylcholinesterase. (biomedcentral.com)
  • high
  • The best five-features pharmacophore model, which includes one hydrogen bond donor and four hydrophobic features, was generated from a training set of 62 compounds that yielded a correlation coefficient of R = 0.851 and a high prediction of fit values for a set of 26 test molecules with a correlation of R 2 = 0.830. (biomedcentral.com)
  • The relatively high affinity of Compound A for butyrylcholinesterase was due to the additional hydrophobic interaction between the 2-thiophene moiety of Compound A and Ile69. (biomedcentral.com)
  • function
  • All of the nicotinic antagonists with significant muscarinic receptor activity had two or three quaternary nitrogens, and the potency of a series of these compounds was a function of the distance between quaternary nitrogens. (aspetjournals.org)