Loading...
  • rRNA
  • In plants, several DExD/H-box RHs have been demonstrated to be associated with plant development and abiotic stress tolerance through their functions in modulating pre-rRNA processing. (frontiersin.org)
  • In this review, we summarize the pleiotropic roles of DExD/H-box RHs in rRNA biogenesis and other biological functions. (frontiersin.org)
  • In this review, we will focus on the emerging roles of plant nucleolus DExD/H-box RHs in rRNA biogenesis, and summarize the current research on their functions in growth and stress responses. (frontiersin.org)
  • cellular
  • In human and yeast cells, many DExD/H box RHs participate in multiple steps of ribosome biogenesis and regulate cellular proliferation and stress responses. (frontiersin.org)
  • describe
  • We also describe the overall function of the DExD/H-box RH family in ribosome biogenesis based on data from human and yeast. (frontiersin.org)
  • regulation
  • Importantly, this region of p68 lies outside the conserved helicase core and was previously shown by us to be essential for transcriptional regulation by p68. (biomedcentral.com)
  • Yeast
  • Over the past several decades, the functions of DExD/H-box RHs have been widely studied in yeast and human cells. (frontiersin.org)
  • highly
  • We have also shown that p72, a helicase that is very highly related to p68 and that had previously been suggested to act in an analogous fashion to p68 [ 3 ], poorly coactivates ERĪ± in standard transcriptional coactivation assays, using ER-responsive promoters. (biomedcentral.com)