Database of human genetic variants databases genetic. Medical search. Frequent questions

A curated database of candidate human ageing-related genes and genes associated with longevity and/or ageing in model organisms. (senescence.info)
A curated database of genes associated with dietary restriction in model organisms either from genetic manipulation experiments or gene expression profiling. (senescence.info)
Database of human genes associated with cellular senescence. (senescence.info)
BioSystems currently contains biological pathways from the Kyoto Encyclopedia of Genes and Genomes (KEGG) and the EcoCyc ( Escherichia coli K-12 MG1655) subset of the BioCyc databases and is designed to accommodate other data in the future. (nih.gov)
These are designed by a laboratory to include genes commonly associated with a broad phenotype (e.g., cardiomyopathy, ataxia, intellectual disability) or a recognizable syndrome with genetic heterogeneity (e.g. (nih.gov)
2 3 The HGP demonstrated that a relatively limited number of genes could be identified in the human genome, which substantiated the theory that complex biological processes were regulated on other levels than DNA sequence alone. (bmj.com)
Allele frequencies of pathogenic variants in ClinVar, as well as variants expected to be pathogenic through the nonsense-mediated decay (NMD) pathway, were analyzed to study the burden of pathogenic variants in 79 genes of clinical importance. (biomedcentral.com)
Therefore, we expanded the analysis to examine the distributions of NMD expected variants in 77 additional genes. (biomedcentral.com)
however, their applications are limited to genes for which high-quality curated lists of pathogenic variants are available. (biomedcentral.com)
The U.S. Department of Energy (DOE) and the National Institute of Health (NIH) launched the Human Genome Project in 1990 with the purpose of identifying and mapping all the genes within the human body. (darkdaily.com)
This study lasted for 13 years and determined that there are an estimated 20,000 to 25,000 genes in the human body. (darkdaily.com)
Methods A next-generation sequencing (NGS) panel was created for the human TRPV1 gene and in addition, for the leukotriene receptors BLT1 and BLT2 recently described to modulate TRPV1 mediated sensitisation processes rendering the coding genes LTB4R and LTB4R2 important co-players in pharmacogenetic approaches involving TRPV1. (researchgate.net)
The NGS workflow was based on a custom AmpliSeq™ panel and designed for sequencing of human genes on an Ion PGM™ Sequencer. (researchgate.net)
NCBI has become a central repository for genomic sequence data in humans and other species and has developed many other public databases, such as dbSNP (for single nucleotide polymorphisms, or SNPs) and Entrez Gene (for genes) ( 5 , 6 ). (cdc.gov)
The HUGO Gene Nomenclature Committee maintains a database of approved, unique gene names and symbols, which currently includes more than 28,000 genes ( https://www.genenames.org ) ( 9 ). (cdc.gov)
Amino acid changes for variants in protein genes are predicted according to the human mitochondrial genetic code . (mitomap.org)
The Dupuis lab develops statistical approaches to identify specific genes or genetic variants that inﬂuence complex phenotypes through their associated quantitative traits, which are traits that can be measured numerically, such as height or blood pressure in humans, and seed size or oil content in plants. (bu.edu)
To detect pathogenic variants in multiple deafness genes, in addition to novel candidate genes associated with hearing loss, whole exome sequencing (WES), followed by analysis prioritizing genes categorized in four tiers, were applied. (biomedcentral.com)
Our findings demonstrate that four-tier assessment of WES data is efficient and can detect novel candidate genes associated with hearing loss, in addition to pathogenic variants of known deafness genes. (biomedcentral.com)
For comprehensive investigation of the genetic heterogeneity of diseases with a wide range of causative genes, such as hearing loss, and to identify novel candidate genes, WES analysis overcomes the limitations of targeted analysis and is considerably more cost-effective than whole genome sequencing (WGS) analysis. (biomedcentral.com)
In this study, we sought to explore the wide spectrum of genetic heterogeneity associated with hearing loss in Japan, and to discover novel candidate genes associated with hearing loss, using trio analysis of probands and their parents, and four originally developed gene groups ranked by priority (tiers), as a new strategy to filter candidate variants. (biomedcentral.com)
Using this strategy, we successfully detected candidate pathogenic variants in 11 previously reported deafness genes in 21 families, as well as eight single candidate deafness genes in 10 families. (biomedcentral.com)
Variants in blood pressure genes and the risk of Accardi R, Rubino R, Scalise M et col . (2011). (who.int)
Antimicrobial resistance occurs through different mechanisms, which include spontaneous (natural) genetic mutations and horizontal transfer of resistant genes through deoxyribonucleic acid (DNA). (who.int)

Pathogenic variants in the Longitudinal Early-onset Alzheimer's Disease Study cohort Alzheimers Dement. (usc.edu)
Many inherited disorders and phenotypes are genetically heterogeneous - that is, pathogenic variants in more than one gene can cause one phenotype (e.g., dilated cardiomyopathy, ataxia, hereditary hearing loss and deafness) or one genetic disorder (e.g. (nih.gov)
Importantly, we observed no difference in the distributions of pathogenic variants expected to be lead to NMD compared to those that are not. (biomedcentral.com)
Furthermore, pathogenic variants with allele frequencies greater than 0.01% were well characterized in publications and included many founder mutations. (biomedcentral.com)
However, the recommendation provides no detailed guidance for determining the expected allele frequency of pathogenic variants. (biomedcentral.com)
Whole exome sequencing (WES), involves sequencing of coding exons comprising approximately 2% of the whole human genome, which are estimated to contain approximately 85% of pathogenic variants associated with monogenic disease [ 6 ]. (biomedcentral.com)

In the analysis of genomic variants , data sharing is proving to be an important tool for researchers, scientists, pathologists, and clinical laboratory scientists. (darkdaily.com)
The Center's overarching goal is to help the biomedical community use genomic information to better understand human health and disease. (feedburner.com)
The international Human Genome Project's early commitment to data sharing helped stimulate the construction of other, online genomic data repositories and tools for use by researchers and the public. (cdc.gov)
Human genome epidemiology is the basic science for translating genomic research, relating genetic variation with variability in health status among well-defined groups of people. (cdc.gov)
PG2 integrates genome and transcriptome sequencing to incorporate protein variants containing amino acid substitutions, insertions, and deletions, as well as non-canonical reading frames, exons, and other variants caused by genomic and transcriptomic variation. (biorxiv.org)
We benchmarked PG2 using synthetic data and genomic, transcriptomic, and proteomic analysis of human leukemia cells. (biorxiv.org)

ClinVar is a public archive of submitted reports of clinically relevant human genetic variants and their relationships to phenotypes, with supporting evidence. (nih.gov)
ClinVar provides standardized nomenclature for variants and phenotypes, a review status for variants, and links to related NCBI literature and molecular databases. (nih.gov)
Is it possible for the NCBI ClinVar public archive to receive, store, and retrieve data generated from a resource supported by this RFA or should an applicant plan to create a separate database? (genome.gov)
Currently, approximately 85% of sequence variants in ClinVar have been reported only by single submitters and, despite growth in both the number of ClinVar participants and total entries, this percentage has remained steady [ 1 ]. (biomedcentral.com)
With such limited data, more than 40% of the variants in ClinVar are still designated as variants of uncertain significance. (biomedcentral.com)
Accessible databases like ClinVar , which was launched by the National Institute of Health (NIH) in 2013, have emerged to aggregate genetic sequencing with acceptable results. (darkdaily.com)
ClinVar is an archive of compiled data relating to genotype and phenotype variations among humans. (darkdaily.com)
A key challenge with a database like ClinVar is that different medical laboratories may interpret test outcomes in contrasting manners. (darkdaily.com)
She recently led an examination of some data located in the ClinVar database. (darkdaily.com)
Rehm's lab, along with the University of Chicago , Ambry Genetics, and GeneDx, analyzed over 6,000 variants submitted to ClinVar by two or more separate labs. (darkdaily.com)

Comprising only 1%-2% of the human genome, the exome nonetheless contains the majority of currently recognized disease-causing variants. (nih.gov)
A typical research question can be to screen datasets from a number of patients for potentially disease-causing variants, or to compare variants between affected and unaffected members of one family in order to identify a genetic variant that co-segregates with the disease. (lu.se)

The human exome includes all coding nuclear DNA sequences, approximately 180,000 exons that are transcribed into mature RNA. (nih.gov)
The diagnostic utility of exome sequencing has consistently been 20%-30% (i.e., a diagnosis is identified in 20%-30% of individuals who were previously undiagnosed but had features suggestive of a genetic condition) [ Gahl et al 2012 , Lazaridis et al 2016 ]. (nih.gov)
Recent publications of large population sequencing data, such as the Exome Aggregation Consortium (ExAC) database, provide an opportunity to characterize with accuracy and precision the frequency distributions of very rare disease-causing alleles. (biomedcentral.com)
With the increasing adoption of whole-genome, exome, and panel-based genetic testing, the detection of novel, previously uncharacterized sequence variants has increased dramatically. (biomedcentral.com)
After the release of the Exome Variant Server (EVS) dataset, Norton et al. (biomedcentral.com)
The Genome Aggregation Database (gnomAD) aggregates exome and genome sequencing data from a wide variety of large-scale sequencing projects. (mitomap.org)

BioSample contains descriptions of biological source materials used in studies that have data in other NCBI molecular databases such as Assembly, Nucleotide and SRA. (nih.gov)
The variant analysis revealed over 3.6 million single nucleotide variants and 5 46 681 small insertions and deletions including about 2.7 % of novel (unreported) variants. (ijpsonline.com)
This rule also applies to variants in single residue stretches (mono-nucleotide or amino acid) or tandem repeats. (mitomap.org)
For example, most human tissues in healthy individuals acquire somatic nucleotide substitutions, insertions, deletions and DNA rearrangements, leading to the production of variant protein isoforms. (biorxiv.org)

With certain exceptions, such as founder mutations, the rarity of a variant is a prerequisite for pathogenicity. (biomedcentral.com)
The remaining 14 variants were previously published founder mutations. (biomedcentral.com)
By the 1990s, OMIM was adding more than 150 disease-related genetic variants per year, nearly all of them rare mutations discovered in families ( 1 ). (cdc.gov)
The Human Genome Variation Society (HGVS) has begun a grass-roots effort to compile a list of locus-specific databases (LSDBs), which are curated collections of mutations, often reported with associated phenotypic information ( 10 ). (cdc.gov)
Approximately 1 in every 500 newborns exhibits a degree of hearing loss, and more than half of cases are associated with genetic mutations [ 1 ]. (biomedcentral.com)

The CRVR resource should be freely accessible to the public and NHGRI is committed to supporting the CRVR resource as long as there is sufficient evidence that the resource is improving the assessment of the clinical relevance of genetic variants, provides utility to the community and funds are available to continue the program. (genome.gov)
The frequency of a variant in the general population is a key criterion used in the clinical interpretation of sequence variants. (biomedcentral.com)
Furthermore, the usefulness of such data for clinical variant interpretation was limited because allele frequencies were calculated using small datasets, resulting in frequency estimates of limited accuracy. (biomedcentral.com)
Rehm also has been striving to ensure consistency in reporting among clinical laboratories, gene testing companies, accrediting organizations, and journals, in regards to variant interpretations. (darkdaily.com)

Entrez is NCBI's primary text search and retrieval system that integrates the PubMed database of biomedical literature with 38 other literature and molecular databases including DNA and protein sequence, structure, gene, genome, genetic variation and gene expression. (nih.gov)
Recent advances in nucleic acid sequencing now permit rapid and genome-scale analysis of genetic variation and transcription, enabling population-scale studies of human biology, disease, and diverse organisms. (biorxiv.org)
However, recent studies in many organisms and in humans have revealed significant protein sequence variation due to the presence of somatically acquired genetic variants, alternative transcription, and mRNA splicing, which are not necessarily annotated in reference databases. (biorxiv.org)
Human Variome Project quality assessment criteria for variation databases. (lu.se)
Guidelines for reporting and using prediction tools for genetic variation analysis. (lu.se)

1 The idea that the field of molecular biology needed to move from studying isolated biological molecules towards a broad analysis of large sets of biological molecules was underscored with the completion of the human genome project (HGP) in 2001. (bmj.com)
HUGO has, over the years, played an essential role behind the scenes of the human genome project. (humanvariomeproject.org)
With its mission to promote international collaborative efforts to study the human genome and tackle the myriad of issues raised by knowledge of the genome, HUGO has had noteworthy successes in many vital aspects of the human genome project. (humanvariomeproject.org)

Conserved Domains is a database of protein domains represented by sequence alignments and profiles for protein domains conserved in molecular evolution. (nih.gov)
In this context, we have recently reported a complete sequence analysis of a male from the Western part of The contemporary Indian population is an admixture of several waves of human migration from various directions, which is believed to have been segregated into various communities over the past 2000 y or so[ 2 ]. (ijpsonline.com)
The observations made in this study suggest that, with certain caveats, a very low allele frequency threshold can be adopted to more accurately interpret sequence variants. (biomedcentral.com)
According to the joint consensus recommendation for the interpretation of sequence variants by the American College of Medical Genetics and Genomics (ACMG) and the Association for Molecular Pathology (AMP), an "allele frequency greater than expected for disorder" is strong evidence for a benign classification [ 2 ]. (biomedcentral.com)
For example, the UCSC Human Genome Browser , launched in 2002, created a framework for displaying multiply annotated sequence data at any scale throughout the genome ( 7 ). (cdc.gov)
Recently, NCBI embraced these efforts by allowing users to search, annotate, and submit human genome sequence variants to the dbSNP database by using HGVS standard nomenclature ( 11 ). (cdc.gov)
Sequence alterations, copy number variants and short tandem repeats in human DNA can be detected. (lu.se)

In the not-so-distant past, genetic testing was only performed in relation to specific diseases and conditions. (darkdaily.com)
11 And human diseases, including cancer in particular, tend to be defined by the presence of proteins with altered and pathogenic sequences. (biorxiv.org)

Since its inception in 2006, the Human Variome Project has been working with WHO to raise the profile of genetics and genomics within national health ministries. (humanvariomeproject.org)
The WHO was a co-sponsor of the inaugural meeting of the Human Variome Project in 2006. (humanvariomeproject.org)
In 2011, members of the Human Variome Project International Coordinating Office staff were asked by WHO to assist in the undertaking of the WHO Grand Challenges in Genomics and Public Health Project and served on the Executive Committee. (humanvariomeproject.org)
This relationship led to a joint research project between Human Variome Project, the PHG Foundation and WHO to map global activity in genetics, genomics and global health in 2012. (humanvariomeproject.org)
Both the wider Human Variome Project and UNESCO recognise that progress in genetics and genomics is giving people new power to improve health. (humanvariomeproject.org)
Human Variome Project country nodes: documenting genetic information within a country. (lu.se)

HGVS standard nomenclature Human Genome Epidemiology (2nd ed. (cdc.gov)

Guidelines for establishing locus specific databases. (lu.se)
Recommendations for locus-specific databases and their curation. (lu.se)

More detailed help is available for the individual Entrez databases in the NCBI Help Manual sections on the NCBI bookshelf. (nih.gov)
BioProject provides a central point to link to all data associated with a project in the NCBI molecular and literature databases. (nih.gov)
Perhaps the most prominent and widely used NCBI database is PubMed , a continuously updated, public database of more than 18 million citations for biomedical literature. (cdc.gov)
Entrez is the search engine that allows searching across all NCBI databases. (cdc.gov)

Particularly, Y-chromosome and mitochondrial haplogroups have helped to develop a high resolution human migration map during the past 100 000 y. (ijpsonline.com)

Rejuvenation therapies aim to reverse or repair age-related cellular changes such as molecular waste, calcification , tissue stiffening , loss of stem cell function , genetic alterations, and impaired energy production . (fightaging.org)

This grant from the National Human Genome Research Institute (NHGRI) funds the Center for Big Data in Translational Genomics, a multi-institutional partnership based at UC Santa Cruz and led by David Haussler, professor of biomolecular engineering and director of the UC Santa Cruz Genomics Institute. (feedburner.com)

Curating gene variant databases (LSDBs): toward a universal standard. (lu.se)

Students will gain knowledge in human genetic variability and DNA repeats, and skills in analyzing high-throughput sequencing data, algorithm design and testing, and database development. (bu.edu)

Analyses using the AnAge database to study the evolution of longevity and ageing in vertebrate lineages. (senescence.info)
This project involves developing statistical analyses which combine genome wide association results with prior information from "omics" studies (gene variant functionality, gene expression, methylation, metabolomic data, and proteomic data) to determine regions with common or rare genetic variants that are potentially causally associated with traits of interest. (bu.edu)
The bioinformatician works with bioinformatic analyses of genetic data from high throughput genetic sequencing from patients and families with Parkinson disease, dementia, other movement disorders and cerebrovascular disorders. (lu.se)
Regional analyses of human infections with avian influenza subtypes revealed distinct epidemiologic patterns that varied across countries, age and time. (who.int)
As infected animals and contaminated environments are the primary source of human infections, regional analyses that bring together human and animal surveillance data are an important basis for exposure and transmission risk assessment and public health action. (who.int)

Curing Aging and the Science of Immortality presents possible approaches to retard and reverse human aging. (senescence.info)

This document is an overview of the Entrez databases, with general information on searching and displaying data. (nih.gov)
Most importantly Entrez integrates data with links within and between databases. (nih.gov)
New databases are added as biomedical science advances and new kinds of data become available. (nih.gov)
Subsequently, significant work has been done on Indian genomes but not much variant data from the Indian population has been added to the human genome variant database[ 2 - 7 ]. (ijpsonline.com)
The reference Human Genome and related variant databases need to be enriched with data from underrepresented populations. (ijpsonline.com)
A comparison of neuroelectrophysiology databases Sci Data. (usc.edu)
We have undoubtedly entered an era in which detection of variants far outpaces the ability of researchers to gather genetic data or generate experimental data to assess potential phenotypic consequences. (biomedcentral.com)
One class of empirical data, however, has great potential for improving variant interpretation: population allele frequency data. (biomedcentral.com)
After studying the data, the group discovered they were in concordance for classifications for 88% of the variants. (darkdaily.com)
Rehm sees the importance of creating a community-driven approach, supported by a massive effort in data sharing, as necessary to improve knowledge and consistency in classifying variants. (darkdaily.com)
Rehm also would like insurers to require that medical laboratories share their data on variant interpretation before the insurer grants coverage. (darkdaily.com)
The UCSC Genome Browser Database has continued to evolve, adding many web-based applications for viewing, manipulating, and analyzing the data ( 8 ). (cdc.gov)
Additionally, an online database will be created to store and analyze the variant data. (bu.edu)

We have standardized our variant notation to follow the 3' rule of HGVS (see their statement below). (mitomap.org)

Discrepancy between pedigree inheritance and genetic inheritance was present in one family. (biomedcentral.com)

Their application in human observational studies (HOS) has become feasible in recent years due to a spectacular increase in the sensitivity, resolution and throughput of OMICS-based assays. (bmj.com)
To illustrate the current status of the application of OMICS in OEH research, we will provide examples of studies that used OMICS technologies to investigate human health effects of two well-known toxicants, benzene and arsenic. (bmj.com)

They then reviewed the 724 variants about which there was disagreement and eventually came to a consensus on 86% of those variants. (darkdaily.com)
However, most proteomic studies rely on consensus databases to match spectra to peptide and proteins sequences, and thus remain limited to the analysis of canonical protein sequences. (biorxiv.org)

The known variants were analyzed for their health and disease relevance and drug pharmacogenetic profile. (ijpsonline.com)

The most ambitious, even if distant, goal of gerontological research is to make aging optional, to develop a cure for aging , and the social implications of a radical increase in human lifespan due to scientific breakthroughs are also discussed . (senescence.info)
The Summit brings together startups, members of the longevity venture capital / investor ecosystem, and researchers interested in founding or joining a startup - all aiming to create therapies to vastly extend the healthy human lifespan. (fightaging.org)

The vast diversity of tests available range from carrier testing for genetic disorders, and diagnostic testing for genetic or chromosomal conditions, to prenatal diagnosis and newborn screenings, to genealogical and paternity testing to forensic analysi s. (darkdaily.com)

The method adds a large amount of genetic information as a basis for complete analysis of TRPV1 ion channel genetics and its functional consequences. (researchgate.net)
Students will become familiar with genetic studies and software for genetic analysis, and will explore publicly available databases to assign putative function to sets of variants. (bu.edu)
PG2 can be integrated with current and emerging sequencing technologies, assemblers, variant callers, and mass spectral analysis algorithms, and is available open-source from https://github.com/kentsisresearchgroup/ProteomeGenerator2 . (biorxiv.org)

it is an essential part of the messy, human process of bringing new technology from the laboratory to the clinic. (fightaging.org)

The Human Genome Organization (HUGO) was founded in 1988 to foster coordination among large-scale human genome mapping and sequencing projects around the world. (cdc.gov)

The Human Genome Organisation (HUGO) is an international organisation of scientists involved in human genetics. (humanvariomeproject.org)

Telomeres and Telomerase presents the telomeres, their maintenance mechanisms, and their relation to human aging. (senescence.info)

Multisite ALLFTD study modeling progressive empathy loss from the earliest stages of behavioral variant frontotemporal dementia Alzheimers Dement. (usc.edu)
Human Aging Model Systems introduces and discusses the different model organisms used to study human aging. (senescence.info)
In this review we define the field of occupational and environmental health (OEH) research as the study of interactions between the following domains: environment (the exposome), 4 individual (genetic) susceptibility (the (epi)genome), and biological outcomes (the responsome) 5 ( figure 1 ). (bmj.com)
The study team was, however, unable to reach a definitive agreement on 33 variants within the study. (darkdaily.com)
E7 from human papil omavirus type 16 cooperate to cancer: the European prospective investigation into doi:10.1093/carcin/bgp321 PMID:20047954 target the PDZ protein Na/H exchange regulatory cancer and nutrition study. (who.int)
The primary aim of this study was to examine the associations between 10 genetic variants and the intake of total sugar, added sugar, and sugars with sweet taste (i.e., monosaccharides and sucrose) in a middle-aged Swedish population. (lu.se)

Since the first confirmed human infection with avian influenza A(H5N1) virus was reported in Hong Kong SAR (China) in 1997, sporadic zoonotic avian influenza viruses causing human illness have been identified globally with the World Health Organization (WHO) Western Pacific Region as a hotspot. (who.int)
The pandemic potential of avian influenza viruses gained larger recognition in 1997 when the first known human infection with avian influenza A(H5N1) virus was reported in Hong Kong SAR (China). (who.int)

With affordable technology and accessible reference genome database, analyzing individual genome has become feasible to understand one's health and associated health related risk factors. (ijpsonline.com)
Comparison of genetic and health risk factors for mild cognitive impairment and Alzheimer's disease between Hispanic and non-Hispanic white participants Alzheimers Dement. (usc.edu)
Gerontology , and its sub-field biogerontology in particular, is the science that studies the aging process to prevent age-related disease and degeneration, preserve health, and prolong human life. (senescence.info)
The Global Alliance is made of up of a diverse, international group of organizations working in healthcare, biomedical research, disease and patient advocacy, life science, and information technology, who come together with the goal of accelerating progress in medicine and human health. (odbms.org)
She has suggested to the Food and Drug Administration (FDA) that it intervene and create regulations for labs that do not share variant interpretations to avert any threat to public health and safety. (darkdaily.com)
The Johnson lab studies the human microbiome, i.e., microbial communities which live in and on the human body and play a vital role in health and disease. (bu.edu)

An overview of current research on the biology of human aging featuring key observations, concepts, and theories. (senescence.info)

Between November 2003 and September 2017, WHO received reports of 1838 human infections with avian influenza viruses A(H5N1), A(H5N6), A(H6N1), A(H7N9), A(H9N2) and A(H10N8) in the Western Pacific Region. (who.int)
As of September 2017, outbreaks associated with A(H5N1) viruses in domestic poultry and wild birds have occurred in more than 60 countries, and sporadic human infections with A(H5N1) viruses have been reported in 16 countries. (who.int)

A curated database of compounds that modulate longevity in model organisms. (senescence.info)

You can survey the species in the database and consult AnAge's statistics . (senescence.info)

2 Co-circulation of influenza A viruses in human and animal reservoirs in shared habitats provides opportunities for these viruses to reassort and acquire a genetic composition that could facilitate sustained human-to-human transmission with potential pandemic consequences. (who.int)

Understanding and accounting for this fact is critical in determining the frequency threshold at which a variant can be considered "greater than expected for disorder. (biomedcentral.com)

However, defining the threshold at which a variant should be considered "too common" is challenging and therefore diagnostic laboratories have typically set conservative allele frequency thresholds. (biomedcentral.com)
For variants not found, please enter your variant in Mitomaster's SNV query box to obtain GenBank frequency and other helpful information. (mitomap.org)

The BioSystems database collects information on interacting sets of biomolecules involved in metabolic and signaling pathways, disease states, and other biological processes. (nih.gov)
The Genetic Architecture of Biological Age in Nine Human Organ Systems medRxiv. (usc.edu)

Through this database, individuals can present and peruse submissions regarding variants found in patient samples. (darkdaily.com)

Anatomy8

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