• A family history-pesticide exposure interaction was also observed for a number of pesticides. (bmj.com)
  • Epidemiological studies examining the association between pesticide exposure and prostate cancer (PC) are heterogeneous, and provide inconsistent results. (bmj.com)
  • The study, which is the first to link differences in adolescents' brain activity to their level of prenatal pesticide exposure, adds to a large body of research about the health effects of organophosphate pesticides. (scienceblog.com)
  • The study found that during executive-function tasks, brain activation was decreased in the prefrontal cortex in teens with higher levels of prenatal pesticide exposure, as compared to teens whose exposure was lower. (scienceblog.com)
  • some study participants were estimated to have relatively low pesticide exposure levels while for others, exposure was much higher. (scienceblog.com)
  • The team saw brain-activity differences during executive-function tasks that correlated to the teens' levels of prenatal pesticide exposure. (scienceblog.com)
  • ABSTRACT In view of the widespread use of pesticides in Egypt and the increasing incidence of leukaemia and lymphoma we aimed to assess pesticide exposure and other selected variables as risk factors for lymphoproliferative disorders (leukaemia and non-Hodgkin lymphoma). (who.int)
  • After these women gave birth, the researchers sampled the umbilical cord blood, which is the same blood that circulates through the fetus in utero, and performed what's referred to as an epigenome-wide association study (EWAS) to search for correlations between blood cotinine levels of the mothers during pregnancy and epigenetic patterns in the babies at birth. (eurekalert.org)
  • In utero exposure to environmental chemicals, such as polychlorinated biphenyls (PCBs), may play a role in the etiology of ASD. (mdpi.com)
  • Selected chemical and physical properties, toxicokinetic and mechanistic data, and inhalation exposure levels from the National Research Council (NRC) and other agencies are also presented. (nationalacademies.org)
  • Very little information is available on the health effects in humans or experimental animals after inhalation exposure to methyl mercaptan. (cdc.gov)
  • however, it is assumed that both inhalation and dermal exposure were probably involved. (cdc.gov)
  • No study by dermal route available, data derived from a well-conducted subchronic 90 day inhalation study in mouse and rat. (europa.eu)
  • Even low levels of smoke from secondhand exposure affect epigenetic marks in disease-related pathways. (eurekalert.org)
  • Estimates of exposure for Canadians or the environment are influenced by certain physical and chemical properties of the substances in the product, product use patterns, release pathways, knowledge of a substance's rate of entry and fate in the body and the environment. (canada.ca)
  • These data collectively suggest that monarch responses to host-plant pesticides are largely sublethal and more pronounced in the adult stage, despite exposure only as larvae. (nature.com)
  • Application of a simple pharmacokinetic model suggests current adult exposure in Ireland to PFOS is below EFSA?s provisional TWI. (epa.ie)
  • In contrast, the model predicts that the maximum concentration detected in human milk in this study, implies a level of adult exposure that would exceed EFSA?s provisional TWI for PFOA. (epa.ie)
  • The study, published today in Environmental Health Perspectives by researchers at Virginia Commonwealth University Massey Cancer Center, is the first to connect secondhand smoke during pregnancy with epigenetic modifications to disease-related genes, measured at birth, which supports the idea that many adult diseases have their origins in environmental exposures - such as stress, poor nutrition, pollution or tobacco smoke - during early development. (eurekalert.org)
  • Industrial soil cleanup levels are based on an adult worker exposure scenario. (wa.gov)
  • And because this study is observational-it was not specifically designed to examine the influence of childhood lead exposure on adult intelligence-the toxin cannot be established as the conclusive cause of diminished intelligence. (newsweek.com)
  • You can view these data under Populations and Vulnerabilities . (cdc.gov)
  • Epidemiological studies on exposure to pesticides and risk of prostate cancer (PC) provide inconsistent results. (bmj.com)
  • No association was found between low exposure to pesticides and PC, but association was significant for high exposure, pooled OR 1.33 (1.02 to 1.63), I 2 =44.8%, p=0.024. (bmj.com)
  • In spite of a weak significant association detected when pooling ORs for high occupational exposure to pesticides, the magnitude of the association was related to the method of exposure assessment used by the original studies. (bmj.com)
  • Positive findings were mostly confined to occupational exposure to specific groups of pesticides or particular groups of those exposed. (bmj.com)
  • The pooled OR for PC with low exposure to pesticides was 1.02, 95% CI (0.88 to 1.17). (bmj.com)
  • Pooled OR of PC when measuring serum pesticide level was 1.12 (0.74 to 1.50), whereas a high significant association was obtained for high occupational exposure to pesticides for studies applying grouped assignment of exposure, 2.24 (1.36 to 3.11). (bmj.com)
  • The Berkeley team has been collecting data since 1999 on pesticides' effects on mothers and children in California's Salinas Valley, a major producer of crops such as lettuce, strawberries, broccoli and spinach. (scienceblog.com)
  • In the end, we have to ask what's more expensive: to have a greater push toward organic farming or to have more individuals who need assistance because they are dealing with long-term effects of exposure to pesticides. (scienceblog.com)
  • RÉSUMÉ Étant donné l'utilisation largement répandue des pesticides en Égypte et l'incidence croissante de la leucémie et du lymphome, nous avons tenté d'évaluerl'exposition aux pesticides et d'autres variables sélectionnées en tant que facteurs de risque des maladies lymphoprolifératives (leucémie et lymphome non-hodgkinien). (who.int)
  • 2016), which are effective for empirically describing individual-level variability in trajectories of exposure to high-poverty neighborhoods over time, but are limited in that they allow the residuals to vary around the estimate for a single trajectory. (researchgate.net)
  • In order to obtain a precise estimate about the risk of indoor radon over a wide range of exposure levels, it will be necessary to perform a pooled analysis of different studies. (europa.eu)
  • For a quantitative assessment, calculated or measured numerical values are used to estimate the exposures. (canada.ca)
  • Monitoring data can provide an estimate of overall exposure from all sources of the substance, including from products. (canada.ca)
  • For studies applying self-reporting of exposure, pooled estimate was 1.34 (0.91 to 1.77), I 2 =0.00%, p=0.493, while a high significant association was detected for grouped exposure assessment, 2.24 (1.36 to 3.11), I 2 =0.00%, p=0.955. (bmj.com)
  • As these kinds of health effects data become available and methods to assess levels of significant human exposure improve, these MRLs will be revised. (cdc.gov)
  • Information from various sources is evaluated to assess the risk to Canadians and the environment from exposure to substances in products. (canada.ca)
  • Heterogeneity was explained by a number of variables including method used to assess exposure. (bmj.com)
  • Having measures for blood lead levels (BLLs) and a measure for age of housing together on the Tracking Network can help assess testing within areas of high risk. (cdc.gov)
  • Finally, cross-period analyses indicate that white children's share of childhood in the most affluent neighborhood type increased steadily beginning in the late 1980s and that black children's exposure to the poorest neighborhood type increased rapidly in the mid-1980s and then declined sharply throughout the first half of the 1990s. (researchgate.net)
  • Timberlake (2007) uses period life tables to predict transitions into neighborhood poverty during childhood, showing important change over time in Black and white children's predicted exposure to neighborhood poverty (or affluence) at different stages of childhood and between periods [57] . (researchgate.net)
  • Jadhav, 2020 ) taking into account the differences in bioavailability, differences between experimental and human exposure conditions and respiratory volumes. (europa.eu)
  • The Life span and inter-generational respiratory effects of exposures to g reenness and a ir p ollution, Life-GAP, research project is the first such project designed to investigate such a large timespan. (uib.no)
  • The project will use data from the Respiratory Health in Northern Europe (RHINE) study. (uib.no)
  • Despite remediation efforts in housing and the environment and declining smoking rates and secondhand smoke exposure in the United States, tobacco smoke continues to be a substantial source of exposure to lead in vulnerable populations and the population in general. (cdc.gov)
  • Following a review of the distribution of variability in toxicokinetic and toxicodynamic parameters for populations of different ages, genders and disease states, ECETOC concluded that human data (Renwick and Lazarus (1998) Reg. (europa.eu)
  • After the site-specific exposure doses have been estimated, they are compared to human health guidelines, such as ATSDR's minimal risk levels (MRLs). (cdc.gov)
  • Estimates of levels posing minimal risk to humans (Minimal Risk Levels, MRLs) may be of interest to health professionals and citizens alike. (cdc.gov)
  • Estimates of exposure levels posing minimal risk to humans (MRLs) have been made, where data were believed reliable, for the most sensitive noncancer effect for each exposure duration. (cdc.gov)
  • MRLs include adjustments to reflect human variability from laboratory animal data to humans. (cdc.gov)
  • In detail, performing oral-to-dermal extrapolation no defalut factor (i.e. factor 1) was introduced (as dermal aborption will not be higher than oral aborption) and a correction factor of 1.4 for differences in human and experimental exposure conditions: workers (5 working days) vs. rats (7 days continuous exposure) have been used. (europa.eu)
  • Compared with cigarettes, G2 and G3 e-cigarettes resulted in significantly lower levels of exposure to a potent lung carcinogen and cardiovascular toxicant. (bmj.com)
  • Positive trend tests indicate that a linear relationship exists between smoke exposure and blood lead levels in youths and adults and that secondhand smoke exposure contributes to blood lead levels above the level caused by smoking. (cdc.gov)
  • Youths with secondhand smoke exposure had blood lead levels suggestive of the potential for adverse cognitive outcomes. (cdc.gov)
  • Each year, an estimated 443,000 people die prematurely from smoking or exposure to secondhand smoke (SHS) and another 8.6 million live with a serious illness caused by smoking (1). (cdc.gov)
  • During the first trimester, all had a concentration of cotinine - a nicotine byproduct - in their blood consistent with low levels of smoke exposure, ranging from essentially none to levels consistent with secondhand smoke. (eurekalert.org)
  • It contains descriptions and evaluations of studies and presents levels of significant exposure for methyl mercaptan based on toxicological studies and epidemiological investigations. (cdc.gov)
  • In this field, the experience gained by the Ardennes-Eiffel study group in co-ordinating and pooling of epidemiological data will be of great use. (europa.eu)
  • Most studies of occupational exposure to methyl mercaptan in the pulp industry also involve exposure to other sulfur-containing compounds such as hydrogen sulfide, dimethyl sulfide, and sulfur dioxide as well as to methyl mercaptan (Kangas et al. (cdc.gov)
  • A single case of death resulting from occupational exposure to methyl mercaptan has been located. (cdc.gov)
  • The National Institute for Occupational Safety and Health (NIOSH) responded to a joint request from the Building Material & Construction Teamster's Union Local 216 and the management at RMC LONESTAR to investigate noise exposures to the drivers of the company's ready-mix concrete trucks. (cdc.gov)
  • The analysis of the results determined that the Occupational Safety and Health Administration (OSHA) action level for the implementation of a hearing conservation program was exceeded in most of the sampled truck drivers. (cdc.gov)
  • Take a thorough medical history, including the patient's occupational and environmental history, to consider all sources of exposure to all possible agents. (medscape.com)
  • 3 In recent years, evidence has also accumulated regarding the potential role of many environmental and occupational exposures. (bmj.com)
  • It is expected that only limited number of data will be available for relatively high exposure levels. (europa.eu)
  • For high exposure, it was 1.33 (1.02 to 1.63), but heterogeneity was detected (I 2 =44.8%, p=0.024). (bmj.com)
  • CO 2 is heavier than air, and that contributes to the development of toxic exposure situations in enclosed spaces. (nationalacademies.org)
  • There are no data to quantify variability in susceptibility to the effects of exposure to 3a,4,7,7a-tetrahydro-4,7-methanoindene in the human population. (europa.eu)
  • We assessed trends in blood lead levels in youths and adults with cotinine-verified tobacco smoke exposure by using 10 years of data from the National Health and Nutrition Examination Survey. (cdc.gov)
  • Geometric mean levels of blood lead are presented for increasing levels of tobacco smoke exposure. (cdc.gov)
  • What we recommend to mothers in general is that no level of smoke exposure is safe," said study lead author Bernard Fuemmeler, Ph.D., M.P.H., associate director for population science and interim co-leader of the Cancer Prevention and Control program at VCU Massey Cancer Center. (eurekalert.org)
  • An environmental guideline or comparison value is a level (concentration) of a chemical in air, soil, or water that is considered safe for human contact. (cdc.gov)
  • Biomonitoring: Population Exposures has data on the concentration of lead in blood for the U.S. population. (cdc.gov)
  • Children who had a "concerning" blood lead concentration reached a socioeconomic level that was, on average, 4.51 points lower than their less-leaded peers by age 38. (newsweek.com)
  • The points in the figures showing no observed-adverse-effect levels (NOAELs) or lowest-observed-adverse-effect levels (LOAELs) reflect the actual doses (levels of exposure) used in the studies. (cdc.gov)
  • I find that black/white differences in childhood exposure to neighborhood poverty are largely accounted for by differences in the probability of being born into a poor neighborhood, and to a lesser degree by differences in rates of upward and downward neighborhood mobility during childhood. (researchgate.net)
  • Furthermore, data available for 3a,4,7,7a-tetrahydro-4,7-methanoindene, together with information available for chemically-related structures , do not raise concern for possible differences in effect within or between species. (europa.eu)
  • PFOS, PFOA, PFBS, and perfluorohexane sulfonate (PFHxS) were all detected frequently in drinking water but concentrations of PFASs were low, and although PFASs were 64 ng/L in one bottled water sample, this fell below a Swedish Action Level of 90 ng PFASs/L. The Irish population?s exposure to PFOS and PFOA via non-dietary sources is well below estimates of dietary exposure elsewhere in Europe. (epa.ie)
  • In such a case, the quantitative exposure estimates may be based on predictive computer models or on the results of environmental monitoring or human biomonitoring studies (measurements of substances in the environment or in people) conducted in Canada. (canada.ca)
  • In other cases, exposures to substances in products are qualitatively determined, meaning estimates are not calculated numerically. (canada.ca)
  • Levels of significant exposure for each route and duration are presented in tables and illustrated in figures. (cdc.gov)
  • While capturing a temporal dimension largely overlooked in early neighborhood research (i.e., duration of exposure) [4], such summary measures may mask dynamic heterogeneity in the sequence and timing of exposure to residential environments between subgroups. (researchgate.net)
  • This study relies on data prior to 1997, however, after which broader sociodemographic change has occurred, and it focuses on the individual's predicted duration of time in neighborhood poverty rather than focusing on identifying the trajectories of neighborhood poverty themselves. (researchgate.net)
  • Thus, the lack of data on non-insecticidal chemistries, either alone or in combination, prevents a broader assessment of pesticide toxicity for non-target Lepidoptera inhabiting agroecosystems. (nature.com)
  • The impact of the methodology applied for assessment of exposure on the pooled OR was evident. (bmj.com)
  • When cotinine levels were higher, the newborns were more likely to have epigenetic "marks" on genes that control the development of brain function, as well as genes related to diabetes and cancer. (eurekalert.org)
  • To solidify their results, the team repeated the analysis in a separate sample of 115 women and found changes to two of the same disease-related epigenetic regions - one that regulates genes involved in inflammation and diabetes and another that regulates cardiovascular and nervous system functions - are correlated with cotinine levels in mothers. (eurekalert.org)
  • The primary purpose of this chapter is to provide public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective of the toxicology of methyl mercaptan and a depiction of significant exposure levels associated with various adverse health effects. (cdc.gov)
  • These distinctions are intended to help the users of the document identify the levels of exposure at which adverse health effects start to appear. (cdc.gov)
  • For example, physicians concerned with the interpretation of clinical findings in exposed persons may be interested in levels of exposure associated with 'serious' effects. (cdc.gov)
  • Public health officials and project managers concerned with appropriate actions to take at hazardous waste sites may want information on levels of exposure associated with more subtle effects in humans or animals (LOAEL) or exposure levels below which no adverse effects (NOAEL) have been observed. (cdc.gov)
  • it suggests further research into exposure to DBDPE and its health effects is a priority. (epa.ie)
  • Despite much scholarly attention to 'neighborhood effects' on children, no study to date has measured the cumulative exposure of children to neighborhood poverty and affluence. (researchgate.net)
  • Here, we assessed the long-term effects of exposure to fluoxetine (FLX), a selective serotonin reuptake inhibitor, during adolescence on behavioral reactivity to emotion-eliciting stimuli. (jneurosci.org)
  • Do air pollution exposures harm health through extensive long-term effects (during the lifespan and across generations)? (uib.no)
  • What are the health effects of exposure to greenness? (uib.no)
  • Even low air pollution levels have adverse health effects over time. (uib.no)
  • This study highlights the effects of exposure to air pollution on mortality risks in Thailand. (nature.com)
  • However, these simultaneous exposures do not elucidate the effects of Hx pre-exposure in the absence of other stimuli on macrophage priming, nor the underlying molecular mechanisms contributing to long-term effects. (frontiersin.org)
  • Tobacco smoke is a source of exposure to thousands of toxic chemicals including lead, a chemical of longstanding public health concern. (cdc.gov)
  • Exposure to toxic chemicals in consumer and industrial products and the environment puts people at increased risk of disease and death. (nrdc.org)
  • A detailed data profile and a legal file can be obtained from the International Register of Potentially Toxic Chemicals, Palais des Nations, 1211 Geneva 10, Switzerland (Telephone No. 988400 - 985850). (inchem.org)
  • The subcommittee's recommendations for CO 2 exposure levels are provided at the conclusion of this chapter along with a discussion of the adequacy of the data for defining those levels and the research needed to fill the remaining data gaps. (nationalacademies.org)
  • In a population with relatively low air pollution exposure, exposure 20 years ago may be more important than current exposure and exposure 10 years ago. (uib.no)
  • Further studies revealed the absence of alterations in the eIF4E mRNA level in the cadmium -treated cells despite their decreased eIF4E protein level. (cdc.gov)
  • About half the participants were tested for lead exposure when they were 11 years old. (newsweek.com)
  • As Thailand transfers its economic growth from an agricultural to an industrial base 1 , it faces increasing levels of air pollution which have been found in other countries to be associated with adverse health consequences. (nature.com)
  • The present study examined the nicotine delivery profile of third- (G3) versus second-generation (G2) e-cigarette devices and their users' exposure to nicotine and select HPHCs compared with cigarette smokers. (bmj.com)
  • Results from samples collected during the summer nesting season from 2011 through 2013 were compared to results from a 2000-1 study that showed levels of polychlorinated biphenyls (PCBs) had not changed significantly, not only in the last 10 years, but during the past 35 years. (usgs.gov)
  • Fuemmeler and colleagues analyzed data from 79 pregnant women enrolled in the Newborn Epigenetics Study (NEST) between 2005 and 2011. (eurekalert.org)
  • In a second experiment, the 4 remaining types of detectors were installed in 5 houses with exposure levels within the range encountered frequently in the study area. (europa.eu)
  • In order to study the validity of the observations over a wide range of exposure levels, the exercise has been extended to some houses within the 200-500 Bq/m{3} exposure range. (europa.eu)
  • In a study by Hipol and Deacon (2013) , they discovered that only 19-33% of patients treated for anxiety disorders received in vivo exposure. (frontiersin.org)
  • There have been several hypotheses about what effect an insult like organophosphate exposure would have on the brain," said experimental psychologist Joseph Baker , PhD, a co-author of the new study. (scienceblog.com)
  • It's really quite amazing that we see a long-term association between these exposures and brain function," said neuroscientist Allan Reiss , MD, a co-author of the study. (scienceblog.com)
  • A new study confirms that childhood lead exposure leads to poorer cognition as adults. (newsweek.com)
  • Now, a new study from Duke University is the latest to confirm that lead exposure not only damages cognitive function but also leads to lower socioeconomic status. (newsweek.com)
  • The researchers examined data from the Dunedin Multidisciplinary Health and Development Study . (newsweek.com)
  • That study, a lifelong periodic examination of more than 1,000 people from Dunedin, New Zealand, which began in the early 1970s, has provided a plethora of data during the past 40 years. (newsweek.com)
  • Because the Dunedin study has so carefully documented the lives of its enrollees, the level of lead in an 11-year-old's bloodstream can be scrutinized as a potential predictor of educational attainment, career, finances and health. (newsweek.com)
  • Kim Dietrich, an environmental epidemiologist at the University of Cincinnati, chronicled an association between childhood lead exposure and violent crime in a long-term study of nearly 300 people. (newsweek.com)
  • Dietrich notes that the Dunedin study is missing data on lead exposure during the earliest years of life, when, for example, normal oral behavior led to toddlers sticking lead-based paint chips in their mouths. (newsweek.com)
  • These findings demonstrate that exposure to FLX during adolescence modulates responsiveness to emotion-eliciting stimuli in adulthood, at least partially, via long-lasting adaptations in ERK-related signaling within the VTA. (jneurosci.org)
  • Our findings support the Thailand government in aiming to reduce high levels of air pollution. (nature.com)
  • These findings provide evidence that hypoxia pre-exposure could lead to persistent and aberrant inflammatory responses in the context of CNS disorders. (frontiersin.org)
  • Despite the common co-occurrence of Hx with neural disease, few studies have investigated how pre-exposure to Hx changes the long-term ability of resident CNS macrophages/microglia to respond to a subsequent inflammatory insult, such as pathogen exposure or a sterile inflammatory stimulus. (frontiersin.org)
  • Such use has led to environmental contamination and human exposure. (epa.ie)
  • May even low pollution levels be harmful for our health? (uib.no)
  • In general, the air pollution levels are higher in north middle provinces than southern Thailand ( Figure 1 ). (nature.com)
  • By inventorying these lines and reporting the data to USEPA, California will have access to funds for the lines' replacement. (nrdc.org)
  • Therefore, risk assessments of existing substances and new substances are carried out under CEPA 1999 and often include looking at the exposure of Canadians and the environment to substances from products. (canada.ca)
  • Moreover, even under a high-end exposure scenario, it falls below the European Food Safety Authority?s (EFSA) provisional tolerable weekly intakes (TWIs) for PFOS and PFOA. (epa.ie)
  • Soil cleanup levels for this presumed exposure scenario shall be established in accordance with this section. (wa.gov)
  • It is essential to evaluate land uses and zoning for compliance with this definition in the context of this exposure scenario. (wa.gov)
  • In the absence of data, conservative assumptions that are protective of human health and the environment are used. (canada.ca)
  • Childhood lead poisoning data on CDC's Tracking Network is currently unavailable. (cdc.gov)
  • View childhood lead poisoning data in maps, charts, or tables using the Tracking Network's data explorer tool. (cdc.gov)
  • Aaron Reuben , a graduate student in clinical psychology at Duke, wondered whether blood lead levels during childhood correlated with any aspects of their adulthood. (newsweek.com)
  • Reuben and his team extracted Dunedin data on childhood blood levels, cognitive function and socioeconomic status. (newsweek.com)
  • Adolescent FLX exposure suppressed depression-like behavior, as measured by the social interaction and forced swim tests, while enhancing anxiety-like responses in the elevated plus maze in adulthood. (jneurosci.org)
  • The NIOSH recommended exposure limit was surpassed in all personal noise measurements. (cdc.gov)
  • We perform a prevalence GBT model, which uses the logit link function and relies on a binary outcome for neighborhood poverty for each sample member and at each time point (in our analysis, we draw on data from 1991 to 2018, but use an individual's age as our time variable). (researchgate.net)
  • Those with the most exposure had the worst outcomes. (newsweek.com)
  • Variation in economic outcomes following lead exposure, says Reuben, "could be accounted for by what was happening in their brains. (newsweek.com)
  • Taken together, our results demonstrate that the exposure of cells to cadmium chloride resulted in cytotoxicity and cell death due to enhanced ubiquitination and consequent proteolysis of eIF4E protein, which in turn diminished cellular levels of critical genes such as cyclin D1. (cdc.gov)
  • Research suggests that exposure therapy is the most robust treatment available for specific phobias ( Deacon and Abramowitz, 2004 ). (frontiersin.org)
  • Prior research has established the greater exposure of African Americans from all income groups to disadvantaged environments compared to whites, but the traditional focus in studies of neighborhood stratification obscures heterogeneity within racial/ethnic groups in residential attainment over time. (researchgate.net)
  • After all, appropriate past exposure determination is a key issue for correct risk estimation. (europa.eu)
  • The principal objective consists in estimating the risk of indoor radon exposure with sufficient precision by means of the case-control method. (europa.eu)
  • Living in an older home is one risk factor that can contribute to higher blood lead levels in children. (cdc.gov)
  • Race/ethnicity and living in poverty are risk factors that can contribute to higher blood lead levels in children. (cdc.gov)
  • By applying protection at mail and web gateway levels, you can stop threats reaching their endpoint targets, greatly reducing your risk as well as securing legacy nodes that may lack protection. (kaspersky.com)
  • Family history of cancer, exposure to X-rays, smoking and use of hair dyes were not risk factors for lymphoproliferative disorders in univariate analysis. (who.int)
  • Exposure of human cell lines, HCT15, PLC/PR/5, HeLa, and Chang, to cadmium chloride resulted in cytotoxicity and cell death, and this was associated with a significant decrease in eIF4E protein levels. (cdc.gov)
  • Previous studies have revealed low levels of BFRs and PFASs in Irish foodstuffs and human milk. (epa.ie)
  • For human health and the environment, exposure assessments of substances in products may be quantitative or qualitative. (canada.ca)
  • Lead levels were evaluated for smokers and nonsmokers on the basis of age of residence and occupation. (cdc.gov)
  • In the United States, the major source of lead exposure among children is lead-based paint and lead-contaminated dust found in buildings built before 1978. (cdc.gov)
  • No safe level of lead exposure has been identified. (cdc.gov)
  • Older homes can have peeling or chipping lead-based paint and high levels of lead-contaminated dust, and have young children living in them. (cdc.gov)
  • But, says Reuben, after eliminating all other potential factors that could affect cognition, "lead exposure was associated with lower IQs down the line. (newsweek.com)
  • In other words, the lead made it harder for the children to succeed financially as adults because their thinking was impaired by the exposure. (newsweek.com)