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  • King's
  • After last week finally brought some confirmation that Idris Elba and Matthew McConaughey were on board Nikolaj Arcel's big screen adaptation of Stephan King's The Dark Tower, there's now some news to say that the film's release date has been pushed back. (starburstmagazine.com)
  • The basic premise of King's The Dark Tower , which encompasses eight novels and even ties-in with other books, follows The Gunslinger on his quest towards a mysterious tower in a world gone to hell. (starburstmagazine.com)
  • fovea
  • The method includes a control of the initial light adaptation, a record of the exact beginning of dark adaptation, and an accurate means of measuring the threshold of the fovea after different intervals in the dark. (biomedsearch.com)
  • 3. The changes which correspond to those in the fovea alone are secured by correcting the above results in terms of the movements of the pupil during dark adaptation. (biomedsearch.com)
  • 4. On the assumption that the photochemical effect of the light is a linear function of the intensity, it is shown that the dark adaptation of the fovea itself follows the course of a bimolecular reaction. (biomedsearch.com)
  • Thus, dark adaptation is faster at the edge of the macula compared to the fovea. (arvojournals.org)
  • In pilot experiments with two early and two intermediate AMD patients, dark adaptation was measured at 5° (adjacent to the fovea) and 12° (just outside the macula). (arvojournals.org)
  • They showed that the luminance that can be detected after dark adapting for several minutes is lower for a target presented in the periphery (at 5° or 10° visual angle with respect to the viewing direction) compared to a target presented at the fovea (at 0° visual angle). (arvojournals.org)
  • When a small test spot is used during dark adaptation, a single branch is found as only cones are present at the fovea. (org.es)
  • Cone dark adaptation was monitored in 10 participants with early AMD and 10 age-matched controls after exposure to three pre-adapting light intensities, using an achromatic annulus (12° radius) centred on the fovea. (city.ac.uk)
  • receptors
  • It was found that Dark-fly did not have poor eyesight, but rather exhibited higher phototaxis ability and displayed lengthened bristles on the head that function as tactile receptors. (yepbooks.org)
  • With recent progress in genome science enabling researchers to perform whole genome sequencing for Dark-fly, a large number of mutations were identified including genes encoding a light receptor, olfactory receptors, and enzymes involved in neural development. (yepbooks.org)
  • illumination
  • In Arabidopsis thaliana , mRNA levels of one of the aquaporin genes, TIP2;2 , increase during dark adaptation and decrease under far-red light illumination, but the effects of light at the protein level and on the mechanism of light regulation remain unknown. (mdpi.com)
  • characteristics
  • The investigators central hypothesis is that IR evokes a visual response in humans after dark adaptation, and the characteristics of this response suggest transient receptor potential (TRP) channel involvement. (clinicaltrials.gov)
  • Drosophila
  • In the present study, the effects of Ca-CaM on light adaptation, light- and chemically induced Ca 2+ release from internal stores, and the resulting inward current were examined using whole-cell patch-clamp and fluorimetric recordings from Drosophila photoreceptor cells. (pnas.org)
  • Although it is almost impossible to demonstrate evolution in the laboratory, this issue can be approached by using an unusual organism, "Dark-fly": Drosophila melanogaster kept in complete darkness for 57 years through 1,400 generations, which corresponds to 28,000 years in terms of human generations. (yepbooks.org)
  • rods
  • Dark-adapted vision in humans is basically devoid of colour because it depends almost entirely on the functioning of rods. (britannica.com)
  • When a larger test spot is used during dark adaptation, a rod-cone break would be present since the test spot stimulates both cones and rods. (org.es)
  • intercept
  • In pilot experiments, intermediate AMD patients who exhibited essentially no dark adaptation in 20 minutes when bleached with a relatively strong flash (≥ 82% effective bleach) had a rod intercept ≤ 20 minutes when bleached with a weaker flash (≤ 56% equivalent bleach). (arvojournals.org)
  • objective
  • The investigators central objective is to test the electrophysiologic response to IR in the dark-adapted retinal and visual pathways. (clinicaltrials.gov)
  • Nevertheless, a high dose of oral vitamin A taken for at least 14 days did not provide any objective improvement in dark-adaptation function in five such patients. (ovid.com)
  • study
  • 1. After a discussion of the sources of error involved in the study of dark adaptation, an apparatus and a procedure are described which avoid these errors. (biomedsearch.com)
  • This pilot study will evaluate the visual response to infrared (IR) in humans after dark adaptation. (clinicaltrials.gov)
  • The next steps are confirmation that our protocol reproducibly discriminates dark adaptation speed across the full range of early and intermediate AMD patients, followed by a multi-year prospective study of AMD patients to validate that dark adaptation impairment predicts imminent visual acuity loss. (arvojournals.org)
  • The study recorded oscillatory potentials in seven patients with type 2 diabetes and eight age-matched control subjects during oxygen inhalation after dark adaptation. (oxforddictionaries.com)
  • Dark adaptation was shown to be highly diagnostic for early AMD across a range of pre-adapting light intensities, and therefore, the lower pre-adapting intensities evaluated in this study may be used to expedite dark adaptation measurement in the clinic without compromising the integrity of the data obtained. (city.ac.uk)
  • This study reinforces the suggestion that cone and rod dark adaptation are good candidate biomarkers for early AMD. (city.ac.uk)
  • Tower
  • Variety stressed that as of last night, The Dark Tower was still in development at Universal, Javier Bardem was inches away from being signed, sealed and delivered to play Roland, and scripting was still underway. (syfy.com)
  • Will The Dark Tower still go forward, and can the first movie still meet its May 17, 2013, release date? (syfy.com)
  • thus
  • By delivering an increased amount of vitamin A to the RPE, it might be possible to overcome a relative deficiency of vitamin A utilization or transport, and thus improve rod dark adaptation. (ovid.com)
  • suggests
  • This important observation suggests that rhabdomeric sGC expression is a fundamental property of locust photoreceptor cells, perhaps linked to photoreceptor dark adaptation in both kinds of eye. (oxforddictionaries.com)
  • luminance
  • Therefore, we conclude that dark adaptation is affected to a great extent by local luminance, even when controlling for veiling luminance. (arvojournals.org)
  • Based on our results, a simple but adequate model is proposed to predict the adaptation luminance threshold for backgrounds having a nonuniform luminance distribution. (arvojournals.org)
  • This can be measured by placing a subject in a dark room, and increasing the luminance of the test spot until the subject reports its presence. (org.es)
  • regeneration
  • After photobleaching, heterozygous KI generated lower levels of 11- cis-r etinal than heterozygous KO at 15 and 30 minutes in the dark, suggesting that the presence of D477G impairs regeneration of 11- cis -retinal. (arvojournals.org)
  • mechanism
  • 5. It is then suggested that the basis of the initial event in foveal light perception is some mechanism that involves a reversible photochemical reaction of which the "dark" reaction is bimolecular. (biomedsearch.com)
  • however, both the site and the mechanism of action of Ca 2+ in light adaptation are still unknown. (pnas.org)
  • place
  • TRANSFORMERS 3 is geared up to be the biggest blockbuster of the decade, and this beautifully illustrated adaptation of the story is the best place to live and re-live the adventure over and over! (comixology.com)