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  • Fluorescence
  • Compounds corresponding to these MS parameters were fractionated using preparative HPLC and their structures were determined to be 1,3-di(1 H -indol-3-yl)propan-2-one ( 1 ) and 1-(1 H -indol-3-yl)-3-(3 H -indol-3-ylidene) propan-2-one ( 2 ) using a combination of high resolution (HR) MS, 1- and 2-dimensional NMR, and UV and fluorescence spectroscopy. (pubmedcentralcanada.ca)
  • At that time, compounds resembling the aromatic amino acids had been shown to possess appreciable fluorescence in the near ultraviolet but the fluorescence of the aromatic amino acids themselves had not yet been unequivocally characterized (although Debye and Edwards had made observations on the phosphorescence of the aromatic amino acids and the position of these phosphorescence bands indicated to McClure the probable existence of fluorescence bands in the near ultraviolet). (wikipedia.org)
  • aromatic
  • NOVEL AROMATIC COMPOUNDS AND THEIR USE IN MEDICAL APPLICATIONS - Pharmaceutical compositions comprising at least one compound of the formulas (Ia) or (Ib) and a pharmaceutically acceptable carrier wherein the symbols have the following meaning -X- is e.g. and Y being e.g. or the pharmaceutically acceptable salts can be applied to modulate the in-vitro and in-vivo binding processes mediated by E-, P- or L-selectin binding. (patentsencyclopedia.com)
  • complex
  • These include: igher levels of reproducibility igher levels of extract cleanliness Reduced sample and solvent requirements Increased sensitivity SOLA has significant advantages for the analyst when processing compounds in complex matrices, particularly in high-throughput bioanalytical and clinical laboratories where reduced failure rate, higher analysis speed, and lower sample/solvent requirements are critical. (docplayer.net)
  • activity
  • As we described, the purified compounds showed strong AHR agonist activity in reporter assays ( 13 ). (pubmedcentralcanada.ca)
  • Subsequently, this compound (still in the form of its racemate) was studied more thoroughly by Chen and co-workers, who confirmed its pressor activity, but observed that it was about one-half as potent as phenylethanolamine after i.v. administration in a cat preparation: a total dose of 5 x 10−6 M (or ~ 1 mg of the HCl salt) caused a maximum rise in blood pressure of 26 mm Hg. (wikipedia.org)
  • cell
  • It was found that monovalent DNP compounds or multivalent DNP(12)HgG did not prevent the induction of tolerance, unlike their capacity to inhibit immunity, suggesting that a tolerance-inducing antigen binds more avidly to the cell membrane than an immunogen. (ox.ac.uk)
  • fluorescence
  • At that time, compounds resembling the aromatic amino acids had been shown to possess appreciable fluorescence in the near ultraviolet but the fluorescence of the aromatic amino acids themselves had not yet been unequivocally characterized (although Debye and Edwards had made observations on the phosphorescence of the aromatic amino acids and the position of these phosphorescence bands indicated to McClure the probable existence of fluorescence bands in the near ultraviolet). (wikipedia.org)
  • protein
  • We designed and synthesized a number of thiazole compounds targeting the protein phosphatase 1C (PP1C) portion of MLCP and examined inhibition of MLCP using the enzyme prepared from pig aorta. (frontiersin.org)
  • acid
  • This compound may be prepared by reacting the corresponding sulfonic acid with excess phosphorus oxychloride (POCl3) at room temperature. (wikipedia.org)
  • Similarity
  • The pharmacological properties of halostachine have some similarity to those of these structurally-related compounds, and Halostachys caspica extracts have been included as a constituent of certain OTC dietary supplements, but halostachine has never been developed as a prescription drug. (wikipedia.org)
  • form
  • The amino-group makes this compound a weak base, capable of reacting with acids to form salts. (wikipedia.org)
  • The presence of the hydroxy-group on the benzylic C of the N-methylphenylethanolamine molecule creates a chiral center, so the compound exists in the form of two enantiomers, d- and l-N-methylphenylethanolamine, or as the racemic mixture, d,l- N-methylphenylethanolamine. (wikipedia.org)
  • Subsequently, this compound (still in the form of its racemate) was studied more thoroughly by Chen and co-workers, who confirmed its pressor activity, but observed that it was about one-half as potent as phenylethanolamine after i.v. administration in a cat preparation: a total dose of 5 x 10−6 M (or ~ 1 mg of the HCl salt) caused a maximum rise in blood pressure of 26 mm Hg. (wikipedia.org)