Checkpoint Kinase 2DNA DamageCell Cycle ProteinsProtein-Serine-Threonine KinasesAtaxia Telangiectasia Mutated ProteinsProtein KinasesGenes, cdcCell CycleG2 PhaseCell Cycle CheckpointsSaccharomyces cerevisiae ProteinsS PhaseDNA ReplicationMitosisSaccharomyces cerevisiaeDNA, FungalNuclear ProteinsDNA-Binding ProteinsPhosphorylationDNA RepairHydroxyureaSchizosaccharomycesUltraviolet RaysTumor Suppressor ProteinsM Phase Cell Cycle CheckpointsIntracellular Signaling Peptides and ProteinsFungal ProteinsSchizosaccharomyces pombe ProteinsMethyl Methanesulfonatecdc25 PhosphatasesS Phase Cell Cycle CheckpointsSpindle ApparatusSignal TransductionG2 Phase Cell Cycle CheckpointsMutationGenomic InstabilityDNA Breaks, Double-StrandedCDC2 Protein KinaseNocodazoleTumor Suppressor Protein p53Gamma RaysCyclin BKinetochoresRadiation, IonizingG1 PhaseSecurinReplication Protein CExodeoxyribonucleasesAnaphaseHeLa CellsReplication Protein AGene Expression Regulation, FungalSaccharomycetalesHistonesNucleic Acid Synthesis InhibitorsGenes, FungalModels, BiologicalChromosomal Proteins, Non-HistoneChromosome SegregationDose-Response Relationship, RadiationTelomereChromosomes, FungalCell Line, TumorRecombination, GeneticRecombinational DNA RepairDNA HelicasesChromatinCaffeineMolecular Sequence DataMutagensras-GRF1Protein BindingDNAGene DeletionCyclin-Dependent Kinase Inhibitor p21Cell LineCdc20 ProteinsApoptosisMetaphaseRNA, Small InterferingMad2 ProteinsCyclin B1HCT116 CellsEpistasis, GeneticAmino Acid SequenceChromosomal InstabilityMeiosisRepressor ProteinsCell DivisionCell NucleusCyclin-Dependent KinasesBRCA1 ProteinEnzyme ActivationDNA Repair EnzymesGenome, FungalEndodeoxyribonucleasesRad51 RecombinaseCyclin-Dependent Kinase 2Carrier ProteinsXenopus Proteins