• genes
  • We have postulated that the spectrin network provides the basis for an „accumulation machine" , able to select and draw protein binding partners together locally into a functional unit, the location a- and b-spectrin isoforms probably being governed by the differentially spliced C-termini of the b-spectrin genes. (kent.ac.uk)
  • This plays a crucial role in the functionality of higher eukaryotes, with humans expressing more than 5 times as many different proteins (isoforms) through alternative splicing than they have genes. (wikipedia.org)
  • mice
  • However, we did not observe any significant differences in pro- and anti-apoptotic proteins of the Bcl-2 family between control and Psmc1fl/fl;CaMKIIα-Cre mice, which may also by effected by p53 and phosphorylated-Akt. (nottingham.ac.uk)
  • kinase
  • Here, we demonstrate that the enzymes responsible for O-GlcNAc cycling, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA) are in a transient complex at M phase with the mitotic kinase Aurora B and protein phosphatase 1. (gallusimmunotech.com)
  • show
  • We further show that KRT8 protein binds to annexin A2, a protein known to mediate apoptosis as well as the redox pathway. (mdpi.com)