The cytoskeletal system is composed of different proteins networks. (pte.hu)
After decades of inconclusive study of membrane receptor proteins, evidence for anesthetic action now points instead to a deeper level inside neurons, in non-polar regions inside the protein walls of cytoskeletal microtubules. (newswise.com)
My initial research started with the understanding of membrane curvature in monoolein-water system using polymer as a proxy for proteins. (ncbs.res.in)
Septins are essential cytoskeletal proteins involved in key cellular processes and have also been implicated in diseases from cancers to neurodegenerative pathologies. (bvsalud.org)
In much the same way that each of our bodies depends on bones for mechanical integrity and strength, each cell within our bodies is governed mechanically by a skeleton of composite materials including protein polymers (such as actin filaments) and motor proteins (myosin), called the cytoskeleton. (nanowerk.com)
The cytoskeletal system is not at thermodynamic equilibrium and this non-equilibrium drives motor proteins that are the force generators in cells. (nanowerk.com)
Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. (scientificlabs.co.uk)
Our result is limited to small cargo diffusivity, which is a reasonable assumption for many slow axonal transport cargos (such as cytosolic and cytoskeletal proteins, neurofilaments, actin, and microtubules) which are transported as large multiprotein complexes or polymers. (asme.org)
Cytoskeletal proteins as targets for organophosphorous compound and aliphatic hexacarbo n- induced neurotoxicity. (cdc.gov)
Microtubules6
Microtubules are cytoskeletal polymers that dynamically remodel to perform essential cellular functions. (vanderbilt.edu)
Microtubules are protein lattice polymers which organize neuronal interiors and regulate synapses. (newswise.com)
Microtubules (MTs) are cytoskeletal elements that play an essential role in cell division and cytoplasmic organization. (ecmbio.com)
However, for the intermediate semiflexible regime, especially relevant for cytoskeletal filaments like F-actin and microtubules, the situation is less clear. (mdc-berlin.de)
And his efforts ultimately paid off, allowing Alushin and his colleagues to produce the highest-resolution images of microtubules-cytoskeletal filaments that give a cell its shape-that had ever been achieved at the time. (rockefeller.edu)
Filaments4
Semi-flexible polymers (actin filaments) subject to hydrodynamic forcing play an important role in cytoskeletal dynamics in the cell. (aps.org)
On cellular scales this motion is actuated by the cytoskeleton, a collection of dynamic polymer filaments and molecular scale motors that convert chemical energy into mechanical work. (njit.edu)
These dyes enabled them to visualize the detailed process of cell division, particularly the movement of the filaments FtsZ and FtsA (cytoskeletal polymers and prokaryotic homologs of the protein tubulin) that determine the site of cell division by driving peptidoglycan synthesizing enzymes to the correct sites. (egybio.net)
Protein6
DNase I binds to the cytoskeletal protein actin. (wikipedia.org)
In the first module the course we discuss the components and properties of the cytoskeletal protein networks. (pte.hu)
To maintain its correct cell shape, H. neptunium requires MreB as well as a coiled-coil rich protein termed CCRP and the non-canonical bactofilins, which are a new class of nucleotide-independent polymer-forming cytoskeletal elements. (uni-marburg.de)
During my PhD, I biochemically characterized a cytoskeletal protein. (ncbs.res.in)
Actin is the most abundant cytoskeletal protein, accounting for 20% of the total protein content in all eukaryotic cells, especially muscle cells. (projectsparadise.com)
These different types of cytoskeletal fibers are polymers which are made up of small protein subunits and held together by non-covalent interactions. (microbiologynotes.org)
Semiflexible polymers1
Here we perform extensive Brownian dynamics simulations to explore the tumbling dynamics of semiflexible polymers over a broad range of shear strength and the polymer's persistence length lp. (mdc-berlin.de)
GSK3-mediated instability of tubulinpolymers is responsible for the f" by Nicole R. Cunningham, Emily M. Hinchcliff '08 et al. (haverford.edu)
Semi-flexible polymer1
The non-equilibrium problem of semi-flexible polymer dynamics is highly challenging due to the coupling between the objects deformations and the flow. (aps.org)
Cellular3
Analysis showed that the byproducts induced toxic responses, including reductions in cellular viability, changes in cellular morphology, and cytoskeletal alterations, however only at high doses of exposure. (cdc.gov)
Much progress has been made in identifying the key molecular players in cytoskeletal assemblies, yet how they self-organize into the complex cellular scale machinery that underlies life remains largely unknown. (njit.edu)
The cellular cytoplasm is a complex environment containing networks of cytoskeletal polymers, membrane bound and membrane-less organelles. (taylor-lab.org)
Dynamics2
A central theme is the use of biophysical tools to control and investigate the non-equilibrium dynamics of DNA and cytoskeletal elements, tumor microenvironment and cell membranes for biomedical applications, from physical gene delivery to cancer cell migration, with a special focus on using cutting-edge microfluidics for cell manipulation and biological characterization. (tudelft.nl)
Polymers exposed to shear flow exhibit a remarkably rich tumbling dynamics. (mdc-berlin.de)
Rheology1
We will employ both experimental and theoretical approaches to understand fundamental issues in a wide variety of applications ranging from bio-microfluidics, (bio)polymer physics, tumor-microenvironment, molecular rheology to cancer treatment. (tudelft.nl)
Alterations1
The second module lays special emphasis on presenting the pathological alterations of the cytoskeletal system and the underlying diseases. (pte.hu)
Mechanics1
In related work we measure the structure and mechanics of cytoskeletal polymers using a variety of imaging, scattering, and rheologic methods. (upenn.edu)
Organization1
The impact of cytoskeletal organization and connectivity on non-specific NP mobility was probed by injecting NPs with 5k PEG brushes (10 nm hydrodynamic diameter) into the cytoplasm of healthy, fibroblasts, and cancerous, fibrosarcoma, cells, as well as within these cells exposed to cytoskeletal destabilizers, cytoclasin D and nocodazole. (upenn.edu)
Intermediate1
The tetramers subsequently aggregate to form larger order polymers that give rise to a keratin intermediate filament. (medscape.com)
Diffusion1
This research demonstrated the sensitivity of intracellular QD diffusion to actin cytoskeletal modifications. (upenn.edu)
Interactions1
Herein, the surface interactions between polymer grafts and the negatively-charged silica colloid attached to an AFM lever are considered as representative interactions between the antibacterial coating and a bacteria/biofilm. (upenn.edu)
Networks1
In this thesis the viscoelastic properties of cytoskeletal networks were investigated using microrheology. (uni-goettingen.de)
Properties3
Addition of nanoclays into a polymer matrix leads to nanocomposites with enhanced properties to be used in plastics for food packaging applications. (cdc.gov)
This Review will first present the structural properties of septins in solution and describe the interplay of septins with cytoskeletal partners. (bvsalud.org)
The bacterial proliferation on these platforms when compared to the measured mechanical properties shows a direct correlation and hence understanding nano-mechanical properties can provide insights into designing new antibacterial polymer coatings. (upenn.edu)
Cells2
Herein, we investigated the effects that byproducts of a polymer polylactic acid-based nanocomposite containing a functionalized montmorillonite nanoclay (Cloisite 30B) could pose to human lung epithelial cells, used as a model for inhalation exposure. (cdc.gov)
Specifically, we show that a kinase (GSK3) is regulated differently in the two cell types and is responsible for a failure of the young cells to develop a mature response to signals (polarization of a cytoskeletal structure). (haverford.edu)
Structure1
Atomic force microscopy (AFM) was employed to study the structure-mechanical property relationship for these mono- and bi- layered polymer grafts at pH 7.4 and pH 4.0, corresponding to physiological and biofilm formation conditions, respectively. (upenn.edu)
System1
Here, I design active molecules and active polymers using squirmer model system. (ncbs.res.in)
Play1
Stimuli-responsive polymer films play an important role in the development of smart antibacterial coatings. (upenn.edu)
Large1
For a flexible polymer these theoretical results are well confirmed by a large body of experimental single molecule studies. (mdc-berlin.de)
He completed his master degree at Isfahan University of Technology and his Ph.D. in Polymer Science from the University of Akron (Ohio, USA). (tudelft.nl)
High1
It binds actin monomers with very high (sub-nanomolar) affinity and actin polymers with lower affinity. (wikipedia.org)