Loading...
  • Lipid
  • The lipid bilayer hypothesis, proposed in 1925 by Gorter and Grendel, created speculation to the description of the cell membrane bilayer structure based on crystallographic studies and soap bubble observations. (wikipedia.org)
  • In 1925 it was determined by Fricke that the thickness of erythrocyte and yeast cell membranes ranged between 3.3 and 4 nm, a thickness compatible with a lipid monolayer. (wikipedia.org)
  • It is in the membrane where a lipid carrier called bactoprenol carries peptidoglycan precursors through the cell membrane. (wikipedia.org)
  • residues
  • In other words, they contain hydrophobic ("moisture-wary") and hydrophilic ("water-loving") ends.The latter (phosphate group) are directed outward from the membrane, the latter (residues from fatty acids) are oriented towards each other. (bayannumara.info)
  • Ligand binding to CD28 triggered the release of the cytoplasmic domain, thus making the basic residues available for binding to the effector kinase Lck and recruiting downstream components of the signaling pathway. (sciencemag.org)
  • substrate
  • NucView® 488 Caspase-3 substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3 activity within live cells in real time. (thomassci.com)
  • By using an SBP, TRAP transporters share some similarity to ABC transporters in that the substrate for the transporter is initially recognized outside of the cytoplasmic membrane. (wikipedia.org)
  • The trapped subtrate is then delivered to the membrane domains of the transporter, where the electrochemical ion gradient is somehow exploited to open the SBP, extract the substrate and catalyse its movement across the membrane. (wikipedia.org)
  • polypeptide
  • Hoober, J. L., 1972, A major polypeptide of chloroplast membranes of Chlamydomonas reinhardi . (springer.com)
  • It was first isolated in 1986 by Stevenson and Goodenough using a monoclonal antibody raised in rodent liver to recognise a 225-kD polypeptide in whole liver homogenates and in tight junction-enriched membrane fractions. (wikipedia.org)
  • Barrier
  • membrane molecules have sufficient kinetic energy to cross the barrier While simple Brownian diffusion is isotropic and homogeneous, hop diffusion is more complex and combines free diffusion, which occurs inside cell membrane compartments, and infrequent intercompartmental transitions (hops). (wikipedia.org)
  • inward
  • This phenotype is common 59474-01-0 IC50 among cell wall peptidase (or amidase) mutants in which the coordination between outer membrane invagination and inward PG growth has been perturbed (Rodolakis cells often displayed an aberrant round morphology and were frequently the widest region of the cells (Fig. 1C, black arrowheads). (healthcarecoremeasures.com)
  • amino acid
  • A wild-type form of p62/E2, in the absence of E1, and two forms having either 15 or 3 of the wild-type 31-amino acid carboxyl cytoplasmic domain were all localized to the basolateral surface. (rupress.org)
  • thickness
  • In an attempt to accept or reject the hypothesis, researchers measured membrane thickness. (wikipedia.org)
  • Independently, the leptoscope was invented in order to measure very thin membranes by comparing the intensity of light reflected from a sample to the intensity of a membrane standard of known thickness. (wikipedia.org)
  • domain
  • Both the cytoplasmic domain and the chondroitin sulfate chain of NG2 appear to have roles in sorting NG2 to subcellular microdomains destined to become retraction fibers. (biologists.org)
  • Alteration of the cytoplasmic domain of the membrane-spanning glycoprotein p62 of Semliki Forest virus does not affect its polar distribution in established lines of Madin-Darby canine kidney cells. (rupress.org)
  • 1972
  • The paucimolecular model immediately became popular and it dominated cell membrane studies for the following 30 years, until it became rivaled by the fluid mosaic model of Singer and Nicolson (1972). (wikipedia.org)