• FITC Anti-Cytokeratin 19 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blot assays. (southernbiotech.com)
  • IHC analysis of human kidney using anti-Keratin K19 antibody (Cat. (progen.com)
  • The primary antibody anti-Keratin K19 (Cat. (progen.com)
  • IHC analysis of human head and neck squamous cell carcinoma using anti-Keratin K19 antibody (Cat. (progen.com)
  • Western blot analysis of MCF-7 lysate with anti-Keratin K19 antibody (Cat. (progen.com)
  • Cells were stained with ARG66324 anti-Cytokeratin 19 antibody [SQab1872] (green) at 1:40,000 and 4°C. DAPI (blue) was used as the nuclear counter stain. (arigobio.cn)
  • The cells were stained with ARG66324 anti-Cytokeratin 19 antibody [SQab1872] (red) at 1:200 dilution in 1x PBS/1% BSA for 30 min at RT, followed by Alexa Fluor® 488 labelled secondary antibody. (arigobio.cn)
  • Immunohistochemistry: Formalin-fixed and paraffin-embedded thyroid cancer tissue stained with ARG66324 anti-Cytokeratin 19 antibody [SQab1872] at 1:40,000 dilution. (arigobio.cn)
  • Western blot: 10 µg of MCF7, Caco-2, HaCat and PC-3 cell lysates stained with ARG66324 anti-Cytokeratin 19 antibody [SQab1872] at 1:1000 dilution. (arigobio.cn)
  • Immunoprecipitation: 0.4 mg of HaCat whole cell lysate immunoprecipitated (1:100) and stained with ARG66324 anti-Cytokeratin 19 antibody [SQab1872]. (arigobio.cn)
  • Western blot analysis of whole cell lysates probed with cytokeratin 18/19 antibody ( VMA00011 ) followed by detection with HRP conjugated Goat anti Human IgG F(ab')2 (1/2500, STAR126P ) and visualized on the ChemiDoc MP with 2 second exposure. (bio-rad-antibodies.com)
  • Human anti Human cytokeratin 18/19 antibody recognizes human cytokeratin 18, a amino acid type I intermediate filament protein expressed by epithelial cells. (bio-rad-antibodies.com)
  • Monoclonal Antibody Analysis of Keratin Expression in Epidermal Diseases: A 48- and 56-kdalton Keratin as Molecular Markers for Hyperproliferative Keratinocytes. (novodiax.com)
  • A detailed inquiry revealed a 42 kDa, Zn 2+ , Mg 2+ -containing metalloprotease with the highest specificity towards casein, albumin and keratin ( Thys and Brandelli, 2006 Thys RCS, Brandelli A (2006) Purification and properties of a keratinolytic metalloprotease from Microbacterium sp. (scielo.br)
  • Your search for reliable Cytokeratin 19 antibodies ends here. (antibodies-online.com)
  • Utilize our Cytokeratin 19 antibodies in your research endeavors for dependable Cytokeratin 19 detection. (antibodies-online.com)
  • Find Cytokeratin 19 Antibodies with a specific Grade. (antibodies-online.com)
  • Find Cytokeratin 19 Antibodies for a variety of species such as anti-Human Cytokeratin 19, anti-Mouse Cytokeratin 19, anti-Rat Cytokeratin 19. (antibodies-online.com)
  • Find Cytokeratin 19 Antibodies validated for a specific application such as WB, FACS, ELISA, IF. (antibodies-online.com)
  • Find available monoclonal or polyclonal Cytokeratin 19 Antibodies. (antibodies-online.com)
  • Find Cytokeratin 19 Antibodies with a specific conjugate such as Biotin, FITC, HRP. (antibodies-online.com)
  • Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification. (southernbiotech.com)
  • For example, mouse thymic epithelial cells react with antibodies for keratin 5, keratin 8, and keratin 14. (wikipedia.org)
  • The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. (bio-biz-navi.com)
  • Immunolocalization of Keratin Polypeptides in Human Epidermis Using Monoclonal Antibodies. (novodiax.com)
  • Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). (southernbiotech.com)
  • The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. (arigobio.cn)
  • The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. (arigobio.cn)
  • Keratin ( / ˈ k ɛr ə t ɪ n / [1] [2] ) is one of a family of structural fibrous proteins also known as scleroproteins . (wikipedia.org)
  • Cytokeratin 17 is a member of the cytokeratin subfamily of intermediate filament proteins which are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. (bio-biz-navi.com)
  • Enzyme-linked immunosorbent assay (ELISA) was employed to measure levels of five serum proteins previously demonstrated to be up-regulated in papillary thyroid cancer (PTC): angiopoietin-1 (Ang-1), cytokeratin 19 (CK-19), tissue inhibitor of metalloproteinase-1 (TIMP-1), chitinase 3 like-1 (YKL-40), and galectin-3 (GAL-3). (biomedcentral.com)
  • Around the histological level the middle ear cholesteatoma is characterized by epidermal cell Angiopoietin-Like 7 Proteins Storage & Stability hyperproliferation [2], differentiation as well as the accumulation of keratin debris [3]. (bet-bromodomain.com)
  • Based on a review of these and other published studies using gene expression analysis, we concluded that YKL-40, Gal-3, cytokeratin 19 (CK19), TIMP-1 and Ang-1 were consistently found to be upregulated. (biomedcentral.com)
  • Normally keratin 4 is not present in the layers of the epidermis, but should be detectable in glandular tissue of the skin ,sweat glands). (insulin-receptor.info)
  • Skin epidermis contains mainly cytokeratins 14 and 19 ,in the basal layer) and cytokeratin 1 and 10 in the cornifying layers. (insulin-receptor.info)
  • Recognition of OOC as a unique entity has long been due, yet its inexplicable radiographic presentation resembling dentigerous cyst, histological likeness to odontogenic keratocyst (OKC) and inconsistent cytokeratin expression profiles overlapping with both as well as with the epidermis, makes it rather confounding. (bvsalud.org)
  • Additionally cytokeratin 14, which is routinely expressed in mitotically active basal layer cells in normal skin and cholesteatoma [10], is expressed in cholesteatoma tissue within a larger extend in comparison with typical auditory canal skin [9]. (bet-bromodomain.com)
  • Keratins demonstrate tissue- and differentiation-specific expression profiles. (southernbiotech.com)
  • Introduction Primary thyroid leiomyosarcoma (LMS) is an extremely rare soft tissue cancer, with only 22 reported cases to date (1‑19). (docksci.com)
  • The expression of cytokeratin 18 is recognized to be upregulated in cholesteatoma tissue compared to healthful auditory canal skin [9]. (bet-bromodomain.com)
  • A type I keratin expressed in a variety of EPITHELIUM, including the ESOPHAGUS, the TONGUE, the HAIR FOLLICLE and NAILS. (harvard.edu)
  • Reacts exclusively with cytokeratin 4 which is present in noncornifying squamous epithelium, including cornea and transitional epithelium. (insulin-receptor.info)
  • The enhanced proliferation can also be manifested in hyperproliferative patterns of cytokeratin 16 and 19 in cholesteatoma epithelium [3]. (bet-bromodomain.com)
  • Histopathological examination of the hematoxylin-eosin (HE)-stained sections showed a cystic cavity lined by orthokeratinized stratified squamous epithelium lining, with surface showing sheaves of keratin arranged in many layers. (bvsalud.org)
  • It was capable to effectively decompose feathers or "soft" keratin of stratum corneum , in contrast to other "hard" hair-type keratins. (scielo.br)
  • In this review, we have discussed the keratinization that occurs in the stratum corneum that follows mutation in the keratin gene "rare disease" pachyonychia congenital an autosomal dominant disorder or hereditary syndrome by any one of a missense mutation in keratin genes such as KRT6A, KRT6B, KRT16 and KRT17. (ijpsr.com)
  • It is found in many simple and some non-keratinizing stratified squamous epithelia and is often co-expressed with keratin 7. (southernbiotech.com)
  • Cytokeratin 18 (CK18) is often co-expressed with cytokeratin 8 (CK8). (bio-rad-antibodies.com)
  • Keratin is a structural protein from the intermediate filament network, i.e., responsible for maintaining the keratinocyte's structural integrity. (ijpsr.com)
  • Keratin 16 is a type I intermediate filament protein present on the tongue, hair follicle and a part of glabrous skin 1 . (ijpsr.com)
  • Electron microscopy reveals loss of desmosomes (epithelial intercellular junctions formed by membrane and submembrane protein complexes), breakdown of desmosome-keratin intermediate filament attachment, and perinuclear aggregates of keratin intermediate filaments. (medscape.com)
  • The CK18/CK8 heterodimer is the major cytokeratin pair found in simple epithelia such as that found in the liver, intestine and breast ducts. (bio-rad-antibodies.com)
  • Examination showed elevation of carcinoembryonic antigen and CA 19-9. (nih.gov)
  • The relevant laboratory results were as follows: WBC 13.11 × 109/L, Alanine Aminotransferase (ALT) 299 IU/L, Total Bilirubin (TBIL) 586.0 μmol/L, albumin 26 g/L, carbohydrate antigen (CA) 19-9 453.5 U/mL, CA 125 21.60 U/mL, Carcinoembryonic Antigen (CEA) 1.73 ng/mL, Alpha-Fetoprotein (AFP) 4.69 ng/mL, Hepatitis B and hepatitis C were both negative. (oncologyradiotherapy.com)
  • Histological analyses indicated the formation of well-differentiated squamous carcinoma cells exhibiting pronounced stratification (basal and suprabasal cells) and keratinization (keratin pearls) with abundant stroma. (tamu.edu)
  • Using the source a bit more to explain what each gene and each zone of genes mean will be helpful, as we currently have no particular examples of a hair keratin. (wikipedia.org)
  • Type I pachyonychia congenita or type I keratin (k9-k20) keratin gene with two chromosomal loci that were clustered on 17q12 and q21 chromosomes. (ijpsr.com)
  • Type II pachyonychia congenital or type II keratin (k1-k8) keratin gene with chromosomal loci that were clustered and has been located on 12q11q-14. (ijpsr.com)
  • Keratin monomers assemble into bundles to form intermediate filaments , which are tough and form strong unmineralized epidermal appendages found in reptiles , birds , amphibians , and mammals . (wikipedia.org)
  • Keratins (also described as cytokeratins ) are polymers of type I and type II intermediate filaments that have been found only in chordates ( vertebrates , amphioxus , urochordates ). (wikipedia.org)
  • The human genome encodes 54 functional keratin genes , located in two clusters on chromosomes 12 and 17. (wikipedia.org)
  • Keratin and filaggrin expression in keratoacanthoma. (harvard.edu)
  • Cytokeratin and keratin 16 make a protein, i.e., filaggrin (protein maker). (ijpsr.com)
  • The degree of cytokeratin 19 positivity in breast cancer distinguishes malignant from benign tumors. (southernbiotech.com)
  • Cytokeratin 19 is also associated with malignant transformation in esophageal and pancreatic cancers. (southernbiotech.com)
  • CTCs were detected in all stages of the Union of International Cancer Control (UICC), in stage I (1/4, 25%), in stage II (4/12, 33.3%), in stage III (5/19, 26.3%) in stage IV (21/33, 63.6%).The detection of CTCs was associated to the UICC stage (p = 0.035) and to the presence of distant overt metastases (p = 0.014). (researchsquare.com)
  • TOA-1, grown on a skim milk/yeast extract medium, biosynthesized a highly stable keratinolytic enzyme with an optimum activity at pH 11.0-11.5 and temperature of 70-75 °C. This 20 kDa serine protease exhibited a high specific activity towards keratin and lower towards casein. (scielo.br)
  • Immunohistochemical study of cytokeratin expression in nevus sebaceous. (harvard.edu)
  • The argument that this represents a reactive inflammatory dermatosis is supported by studies that used immunohistochemical staining to show that these lesions express cytokeratins similar to those seen in other inflammatory dermatoses, such as psoriasis. (statpearls.com)
  • The presented M. luteus isolate exhibits a significant keratinolytic potential, which determines its feasible applicatory capacity towards biodegradation of poultry by-products or formulation of keratin-based feed components. (scielo.br)
  • The type I cytokeratins are clustered in a region of chromosome 17q12-q21. (arigobio.cn)
  • Alpha-keratin (α-keratin) is a type of keratin found in vertebrates . (wikipedia.org)
  • A type I keratin that is found associated with the KERATIN-3 in the CORNEA and is regarded as a marker for corneal-type epithelial differentiation. (wakehealth.edu)
  • Here we investigated the role of IPO13 in the pathogenesis of pterygium and the underlying mechanism including interaction with other cell proliferation-related factors: keratin 17 (K17), a lesional protein and a member of the type I keratins, and c-Jun, a protein of the activator protein-1 complex. (molvis.org)
  • Keratinocytes were packed with protein and converted into the hard cell, generating unique keratin structurally and functionally 2, 3 . (ijpsr.com)
  • [ 25 ] In particular, studies have revealed that keratosis follicularis (Darier disease) keratinocytes displayed abnormal trafficking of the desmosomal protein desmoplakin and abnormal expression of cytokeratins 10 and 14. (medscape.com)
  • Cytokeratin 19 expression was restricted to the basal cell layers, and cytokeratin 4 expression was abundant in suprabasal cells. (tamu.edu)
  • [11] Recent scholarship has shown that sauropsid β-keratins are fundamentally different from α-keratins at a genetic and structural level. (wikipedia.org)
  • Keratin is a protein found in nails, hair and skin that forms tough fibers for strength. (ijpsr.com)
  • Keratin also protects epithelial cells from damage or stress. (wikipedia.org)
  • Using RT-PCR, Western blotting and immunostaining, we show that synemin M is present at both mRNA and protein levels in undifferentiated ES cells as early as pluripotency factor Oct-3/4 and IF keratin 8. (biomedcentral.com)
  • Knocking down synemin in ES cells by shRNA lentiviral particles transduction has no influence on expression of Oct4, Nanog and SOX2, but decreased keratin 8 expression. (biomedcentral.com)
  • Alpha-keratins (α-keratins) are found in all vertebrates. (wikipedia.org)
  • The harder beta-keratins (β-keratins) are found only in the sauropsids , that is all living reptiles and birds . (wikipedia.org)
  • However, beta sheets are also found in α-keratins. (wikipedia.org)
  • This graph shows the total number of publications written about "Keratin-16" by people in Harvard Catalyst Profiles by year, and whether "Keratin-16" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Keratin-16" by people in Profiles. (harvard.edu)
  • Cytokeratin 19 is a member of the keratin family. (arigobio.cn)
  • Among several bacterial classes, actinobacteria remain one of the most important sources of keratin-degrading strains, however members of the Micrococcaceae family are rarely scrutinized in regard to their applicatory keratinolytic potential. (scielo.br)
  • About 54 members of related protein were present in a keratin family. (ijpsr.com)
  • It was shown in the waist, hips, knees, and elbows, with excessive development of keratin in the hair follicle and has shown in that areas where lots of friction occurred 7, 8 . (ijpsr.com)