Cytidine monophosphate, also known as 5'-cytidylic acid or simply cytidylate, and abbreviated CMP, is a nucleotide that is used as a monomer in RNA. (openclipart.org)
Cytidine Monophosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
This graph shows the total number of publications written about "Cytidine Monophosphate" by people in this website by year, and whether "Cytidine Monophosphate" was a major or minor topic of these publications. (umassmed.edu)
Below are the most recent publications written about "Cytidine Monophosphate" by people in Profiles. (umassmed.edu)
Introduction Uridine-cytidine kinase 2 (UCK2) is an enzyme that catalyses the conversion of uridine and cytidine to their monophosphate form of uridine and cytidine in an alternative salvage pathway of pyrimidine biosynthesis [1]. (nanoker-society.org)
Cytidine can form cytidine monophosphate (CMP, i.e. cytidine with a single phosphate group), cytidine diphosphate (CDP, i.e. cytidine with two phosphate groups), and cytidine triphosphate (CTP, i.e. cytidine with three phosphate groups). (biologyonline.com)
Myeloid-specific ablation of LPS-induced cytidine monophosphate kinase 2 (CMPK2), which is rate limiting for mtDNA synthesis, reduced ARDS severity without a direct effect on IL-6. (lu.se)
Choline4
CDP-choline was prepared by the Radiochemical Center of Amercham by an enzymatic process from phosphoryl (14C-methyl) choline and cytidine 5'-triphosphate. (europa.eu)
Cytidine 5'-diphosphocholine, CDP-choline or citicoline, is an essential intermediate in the biosynthetic pathway of the structural phospholipids of cell membranes, especially in that of phosphatidylcholine. (nih.gov)
Upon oral or parenteral administration, CDP-choline releases its two principle components, cytidine and choline. (nih.gov)
Once absorbed, the cytidine and choline disperse widely throughout the organism, cross the blood-brain barrier and reach the central nervous system (CNS), where they are incorporated into the phospholipid fraction of the membrane and microsomes. (nih.gov)
Deaminase activity1
The DYW domain in PPR-DYW proteins provides the cytidine deaminase activity for RNA C-to-U editing and PPR-E+ proteins recruit an atypical PPR-DYW protein to function in RNA editing. (plantae.org)
During digestion, RNA-rich foods are broken-down into ribosyl pyrimidines (cytidine and uridine), which are absorbed intact. (wikipedia.org)
In humans, dietary cytidine is converted into uridine, which is probably the compound behind cytidine's metabolic effects. (wikipedia.org)
Abstract Uridine-cytidine kinase 2 is an enzyme that is overexpressed in abnormal cell growth and its implication is considered a hallmark of malignancy. (nanoker-society.org)
Pyrimidine4
Dietary sources of cytidine include foods with high RNA (ribonucleic acid) content, such as organ meats, brewer's yeast, as well as pyrimidine-rich foods such as beer. (wikipedia.org)
In addition to its role as a pyrimidine component of RNA, cytidine has been found to control neuronal-glial glutamate cycling, with supplementation decreasing midfrontal/cerebral glutamate/glutamine levels. (wikipedia.org)
A pyrimidine nucleoside is one in which the nucleobase is a pyrimidine, such as cytosine in cytidine. (biologyonline.com)
Definition noun plural: cytidines cy·ti·dine, ˈsaɪtɪdiːn A pyrimidine nucleoside that has cytosine attached to the pentose sugar ribose Details Overview A nucleoside is a nucleobase with a five-carbon sugar (either ribose or deoxyribose). (biologyonline.com)
Nucleoside4
Cytidine (symbol C or Cyd) is a nucleoside molecule that is formed when cytosine is attached to a ribose ring (also known as a ribofuranose) via a β-N1-glycosidic bond. (wikipedia.org)
It is an ester of phosphoric acid with the nucleoside cytidine. (openclipart.org)
Cytidine is a nucleoside consisting of cytosine and ribose sugar linked by β-N 1 -glycosidic bond. (biologyonline.com)
KP-1461 , a cytidine analogue belonging to the class of nucleoside reverse transcriptase inhibitors, has a potential use as a treatment for HIV/AIDS. (biologyonline.com)
Nucleosides2
Nucleosides such as cytidine can be produced by de novo synthesis pathways in the liver. (biologyonline.com)
A variety of cytidine analogues are known, some with potentially useful pharmacology. (wikipedia.org)
Deaminases2
The human polydeoxynucleotide cytidine deaminases APOBEC3A, APOBEC3C, and APOBEC3H are capable of mutating viral DNA in the nucleus, whereas APOBEC3A alone efficiently edits nuclear DNA. (pasteur.fr)
However, a role for the APOBEC family of cytidine deaminases is proposed. (lu.se)
Triphosphate3
An example of a nucleotide wherein three phosphate groups are attached to cytidine is cytidine triphosphate (CTP), one of the building blocks of RNA synthesis. (biologyonline.com)
The organic product acivicin inhibits the glutaminase activity of cytidine triphosphate (CTP) synthetase and it is a potent lead compound for medication discovery in the region of neglected tropical diseases, specifically trypanosomaisis. (gasyblog.com)
Protein activation and expression were analysed by western blotting, deoxyribonucleoside triphosphate levels by HPLC, ribonucleotide reductase activity by 14 C-cytidine incorporation into nascent DNA and cell-cycle distribution by FACS. (nature.com)
Deoxycytidine1
Deoxycytidine differs from cytidine by having a hydroxyl group replaced by hydrogen at the 2′ position of the sugar moiety. (biologyonline.com)
Oligodeoxynucleotide1
Heplisav-B (HepB-CpG) uses the immune-stimulating adjuvant, cytidine-phosphate-guanosine oligodeoxynucleotide (CpG-ODN). (msdmanuals.com)
Enzyme2
It is unclear whether intraclonal V gene diversification by somatic hypermutation, which is strictly dependent on the enzyme activation induced cytidine deaminase (AID), is restricted to the early phase of lymphoma clone expansion and later silenced, or whether it remains active throughout malignant proliferation. (bmj.com)
The archaeal enzyme specifically catalyzes the S-adenosyl-L- methionine dependent 2'-O-ribose methylation of cytidine at position 56 in tRNA transcripts. (expasy.org)
Synthesis2
Apart from nucleic acid synthesis, cytidine appears to control neuronal-glial glutamate cycling, with supplementation decreasing midfrontal/cerebral glutamate/glutamine levels. (biologyonline.com)
Synthesis of [4-15NH2]- and [1,3-15N2]cytidine derivatives for use in NMR-monitored binding tests. (bvsalud.org)
Dietary1
Some of the main dietary sources of cytidine are RNA-enriched foods such as organ meats. (biologyonline.com)
Protein1
Thus, we propose a model for PPR-E protein function in RNA editing in which the PPR-E protein recognizes the target site and recruits the trans cytidine deaminase PCW1 with the assistance of bCCP1 and MORFs. (plantae.org)
Structural2
Cytidine is found in all living organisms as a structural component of RNA. (biologyonline.com)
Hou S, Lee JM, Myint W, Matsuo H, Kurt Yilmaz N, Schiffer CA. Structural basis of substrate specificity in human cytidine deaminase family APOBEC3s. (umassmed.edu)
Salt1
We value your input so if you have suggestions regarding new applications for CYTIDINE-2',3'-CYCLOPHOSPHATE MONOSODIUM SALT email us and we will include your contribution on the website. (discofinechem.com)
Family1
The human cytidine deaminase family of APOBEC3s (A3s) plays critical roles in both innate immunity and the development of cancers. (umassmed.edu)
Activation1
Activation-induced cytidine deaminase displays an alternative co-factor for modulating PIM1 expression in diffuse large B cell lymphoma cell lines. (cdc.gov)