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  • Canine
  • Canine cystinuria can be of three types - Type I (autosomal recessive), Type II (autosomal dominant), and Type III (formerly known as non-Type I). (bullsofcrown.nl)
  • To simplify discussions of cystinuria, we have suggested a classification system for canine cystinuria that encompasses both discriminating aspects of the phenotype (for example, gender affected, androgen dependence, and mode of inheritance) and the gene associated with the disease (Brons et al . (vin.com)
  • breeds
  • Cystinuria in Bulldogs and other Mastiff breeds is mostly of the Type III category. (bullsofcrown.nl)
  • Aside from Bulldogs, Mastiff and Bulldog breeds such as the English Mastiff, the Cane Corso, the Italian Mastiff, and the French Bulldog are also prone to this type of cystinuria. (bullsofcrown.nl)
  • Most importantly, in these breeds, urinary aminoaciduria normalized after neutering, making neutering an effective treatment for cystinuria in some, but not all breeds. (vin.com)
  • This variant SLC3A1 allele is not found in androgen-dependent cystinuric dogs of other breeds, several in which cystinuria has a relatively high incidence. (vin.com)
  • Genetics
  • Dr. Ward, a Silver Professor at NYU and chair of the Department of Chemistry, spoke on new medicines being developed to treat cystinuria, and Dr. Sahota, a professor in the Department of Genetics at Rutgers University and a clinical professor in the departments of pathology and urology, spoke on the CDME study. (cystinuria.org)