• According to the most recent revision (2004) of the World Health Organization (WHO) histological classification system for lung tumors ("WHO2004"), currently the most widely recognized typing scheme for pulmonary neoplasia, MCACL is considered a distinctive variant of adenocarcinoma. (wikipedia.org)
  • Informally, some experts have included these tumors as a distinct variant among a spectrum of mucus-producing adenocarcinomas, including - in order of increasing relative extent of cellular mucus production and extracellular mucus accumulation - solid adenocarcinoma, mucoepidermoid carcinoma, mucinous bronchioloalveolar carcinoma, signet ring cell adenocarcinoma, mucinous cystadenocarcinoma, and mucinous "colloid" adenocarcinoma. (wikipedia.org)
  • The 1999 World Health Organization classification system defined MCACL as a cystic adenocarcinoma with copious mucin production that, histologically, resembles (the more common) mucus-producing cystadenocarcinomas originating in the ovary, breast and pancreas. (wikipedia.org)
  • Microscopically, the neoplastic epithelial cells tend to grow along the alveolar walls, in a fashion similar to the mucinous variant of bronchioloalveolar carcinoma, a more common form of adenocarcinoma. (wikipedia.org)
  • This condition is now also referred to as adenocarcinoma in situ, minimally invasive adenocarcinoma, lepidic predominant adenocarcinoma, or invasive mucinous adenocarcinoma. (clinicaltrialsgps.com)
  • Differential diagnosis of MCACL includes secondary metastatic cystadenocarcinomatous lesions, particularly from the pancreas or ovary, mucoepidermoid carcinoma, and pulmonary mucinous bronchioloalveolar carcinoma. (wikipedia.org)
  • In addition of the categories of squamous dysplasia and carcinoma in situ , two additional lesions were added to the group of pre-invasive lesions: atypical adenomatous hyperplasia (AAH) and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). (ersjournals.com)
  • Mucinous cystadenocarcinoma of the lung (MCACL) is a very rare malignant mucus-producing neoplasm arising from the uncontrolled growth of transformed epithelial cells originating in lung tissue. (wikipedia.org)
  • It can sometimes occur within a pulmonary bronchocele, and this tumor entity should be kept in mind after identification of a bronchocele with suspicious or non-prototypical imaging characteristics. (wikipedia.org)
  • There was no clear relationship between the cystic tumor and the liver, which led to the assumption of primary extrahepatic cystic echinococcosis. (biomedcentral.com)
  • We report a case of a huge retroperitoneal cystic mass in a 46-year-old patient who presented with a long-standing, painless progressive abdominal swelling. (biomedcentral.com)
  • Mirizzi syndrome refers to an uncommon phenomenon that results in extrinsic compression of an extrahepatic biliary duct from one or more calculi within the cystic duct or gallbladder . (radiopaedia.org)
  • MRCP classically shows a large impacted gallstone in the gallbladder neck or cystic duct, or signs of inflamed gallbladder causing proximal dilatation of the extra and intrahepatic biliary tree, with distal gradual tapering of the extrahepatic biliary duct caliber to the site of obstruction ref . (radiopaedia.org)
  • The 2004 revision of the WHO classification noted that the tumors tend to be well circumscribed by a partial fibrous tissue capsule with central cystic change and copious mucin pooling. (wikipedia.org)
  • The mouse monoclonal antibody 1D3, developed to detect a high molecular weight mucin found in a number of cystic malignancies of various organs, may be of use in differentiating primary mucinous cystadenocarcinoma of the lung from metastatic lung tumors due to mucinous cystic lesions of the uterus and pancreas, as well as those primary in the colon and stomach. (wikipedia.org)
  • atypical adenomatous hyperplasia and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia. (ersjournals.com)
  • There was no sharp delineation between the abdominal cystic formation and the liver parenchyma. (biomedcentral.com)
  • In a review of 66 cystic pulmonary mucinous lesions, Gao and colleagues reported that p53 expression and a Ki-67 index exceeding 20% is characteristic of MCACL. (wikipedia.org)
  • On exploration, a 3-kg cystic mass was removed. (biomedcentral.com)
  • Abdominal contrast-enhanced computed tomography was suggestive of a thin-walled hypodense cystic mass of size 25.7 × 15 × 14.3 cm in the left side of the abdomen extending from the lesser sac till the left iliac fossa. (biomedcentral.com)
  • Furthermore, there was no evidence of another originating organ association of the huge cystic mass. (biomedcentral.com)
  • A low insertion of the cystic duct into the common bile duct as well as a tortuous cystic duct are thought to be risk factors. (radiopaedia.org)
  • 12. Mucinous cystadenocarcinoma of the parotid gland: report of a case with fine needle aspiration findings and histologic correlation. (nih.gov)
  • The 1999 World Health Organization classification system defined MCACL as a cystic adenocarcinoma with copious mucin production that, histologically, resembles (the more common) mucus-producing cystadenocarcinomas originating in the ovary, breast and pancreas. (wikipedia.org)
  • The mouse monoclonal antibody 1D3, developed to detect a high molecular weight mucin found in a number of cystic malignancies of various organs, may be of use in differentiating primary mucinous cystadenocarcinoma of the lung from metastatic lung tumors due to mucinous cystic lesions of the uterus and pancreas, as well as those primary in the colon and stomach. (wikipedia.org)
  • 14. Mucinous cystadenocarcinoma of the pancreas during pregnancy. (nih.gov)
  • 17. Aspiration cytodiagnosis of mucinous cystadenocarcinoma of the pancreas. (nih.gov)
  • Topics included aging mouse lesions from various strains, as well as the following lesions from various rat strains: rete testis sperm granuloma/fibrosis, ovarian cystadenocarcinoma, retro-orbital schwannoma, periductal cholangiofibrosis of the liver and pancreas, pars distalis hypertrophy, chronic progressive nephropathy, and renal tubule regeneration. (nih.gov)
  • Large tumours may have cystic component, hemorrhage and necrotic areas. (radiologycases.my)
  • 2. Fine needle aspiration cytology of mucinous cystadenocarcinoma of the lung: report of a case with radiographic and histologic correlation. (nih.gov)
  • Lung cancer is more closely linked to chronic obstructive pulmonary disease with airflow compromise than to the disease without significant airway obstruction. (medscape.com)
  • 11. [A case of primary retroperitoneal mucinous cystadenocarcinoma]. (nih.gov)
  • 20. Mucinous cystadenocarcinoma of the spleen - a very rare case of a primary splenic MCN. (nih.gov)
  • In a review of 66 cystic pulmonary mucinous lesions, Gao and colleagues reported that p53 expression and a Ki-67 index exceeding 20% is characteristic of MCACL. (wikipedia.org)
  • 1. Pulmonary mucinous cystadenocarcinoma: report of a case and review of the literature. (nih.gov)
  • 4. Pulmonary mucinous cystadenocarcinoma: report a case and review of CT findings. (nih.gov)