free cysteine
- Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range. (nih.gov)
taurine biosynthetic
- Branched-chain amino acids inhibit the TGF-beta-induced down-regulation of taurine biosynthetic enzyme cysteine dioxygenase in HepG2 cells. (nih.gov)
enzyme
- Cysteine dioxygenase (CDO) is a mononuclear ferrous enzyme located at a branch-point in cysteine metabolism and catalyzes the oxidation of L-cysteine using both atoms of dioxygen. (auburn.edu)
oxidation
- The spectrum of CDO expressed in cell lysate was consistent with Fe(II) and the lysate displayed considerable catalytic activity for cysteine oxidation. (auburn.edu)
- Consistent with the oxidation, purified CDO displayed no activity beyond the background oxidation of L-cysteine. (auburn.edu)
potential biomarker
- Methylated cysteine dioxygenase-1 gene promoter in the serum is a potential biomarker for hepatitis B virus-related hepatocellular carcinoma. (nih.gov)
CDO1
- Prognostic Significance of Promoter DNA Hypermethylation of cysteine dioxygenase 1 (CDO1) Gene in Primary Breast Cancer. (nih.gov)
Type
- Frequent inactivation of cysteine dioxygenase type 1 contributes to survival of breast cancer cells and resistance to anthracyclines. (nih.gov)
human
- Involvement of the Cys-Tyr cofactor on iron binding in the active site of human cysteine dioxygenase. (nih.gov)
