Loading...
  • urine
  • We therefore hypothesized that blood and urine cystathionine levels may be increased in HD patients and that this increase might correlate with disease progression. (plos.org)
  • 6 Therefore, we hypothesized that the levels of cystathionine in both blood and urine may be increased in patients with HD compared to matched controls and that this increase might correlate with disease progression. (plos.org)
  • Activation
  • 2003. Activation of Peroxisome Proliferator-Activated Receptor Gamma and Retinoid X Receptor Results in Net Depletion of Cellular Cholesteryl Esters in Macrophages Exposed to Oxidized Lipoproteins. (uwo.ca)
  • depletion
  • It is concluded that glutathione depletion causes a JNK- and p38MAPK-mediated increase in expression of cystathionine-γ-lyase that promotes flux through the transsulfuration pathway to compensate for loss of glutathione in C6 glioma cells. (ucd.ie)
  • presence
  • Co-incubation of C6 cells with diethylmaleate and the JNK-inhibitor, SP600125, abolished the increase in expression of cystathionine-γ-lyase that had been observed in the presence of diethylmaleate alone. (ucd.ie)
  • significant
  • Incubation of C6 cells with diethylmaleate for 3 h led to a significant reduction in glutathione (63%), whereas expression of cystathionine-γ-lyase was increased by 1.5-fold. (ucd.ie)