• Other target antigens are also postulated to be relevant in the pathogenesis of pemphigus foliaceus. (medscape.com)
  • Using a newly generated monoclonal antibody against Siglec-6 to detect protein expression, this latter study found that Siglec-6 was expressed by placental cytotrophoblasts and syncytiotrophoblasts as well as several human hematopoietic cell lines, including TF-1, HEL, U937, and THP-1 cells. (wikipedia.org)
  • This monoclonal antibody also bound to nearly all human peripheral blood B cells, although more recent reports have not replicated this finding. (wikipedia.org)
  • A hottest embodiment makes use of a novel human monoclonal antibody that binds to a conserved space of the gp41 transmembrane subunit of the virus. (kits-elisa.com)
  • All animals had detectable neutralizing rabies virus antibody titers after vaccination, but one animal failed to meet the World Organization for Animal Health's definition for adequate vaccination (0.5 IU/ml), and two other animals had low antibody titers (0.56 and 0.6 IU/ml). (cdc.gov)
  • The antibody is produced by regular cell traces developed using human B lymphocyte cells collected from a affected individual possessing extreme titers of anti-HIV antibodies. (kits-elisa.com)
  • Initial studies found that Siglec-6 binds to sialyl-Tn antigen (Neu5Acα2-6GalNAcα) but not to Tn antigen (GalNAcα), 6′-sialyl-lactose (Neu5Acα2-6Galβ1-4Glc), or 3′-sialyl-lactose (Neu5Acα2-3Galβ1-4Glc). (wikipedia.org)
  • Next-generation vaccines that utilize T cells could potentially overcome the limitations of current influenza vaccines that rely on antibodies to provide narrow subtype-specific protection and are prone to antigenic mismatch with circulating strains. (mdpi.com)
  • The epidemiology, age distribution, and human leukocyte antigen (HLA) associations distinguish fogo selvagem from nonendemic pemphigus foliaceus. (medscape.com)
  • Overall primary concerns are: extrapolating human clinical studies, seeding durable effective T cell resident memory (Trm), population human leucocyte antigen (HLA) coverage, and the potential for T cell-mediated immune escape. (mdpi.com)
  • Two parallel immunoblots had been operate from same cell lysates using antibodies against the Thr-183/Tyr-185, Thr-180/Tyr-182, and Thr-202/Tyr-204 phosphorylated (ie, turned on) JNK (p-JNK), p38 (p-p38), and Erk1/2 (p-Erk1/2) and against total JNK, p38, and Erk1/2. (californiaehealth.org)
  • Outcomes IL-1to activate JNK, p38, and Erk1/2 pathways was researched by Traditional western blot evaluation using antibodies aimed against Thr-183/Tyr-185, Thr-180/Tyr-182, and Thr-202/Tyr-204 phosphorylated (ie, turned on) JNK, p38, and Erk1/2, respectively. (californiaehealth.org)
  • The plant-orange matter is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. (worldcarecouncil.org)
  • Some studies have found that high levels of antithyroid peroxidase antibody (TPO-Ab) and increased thyroid-stimulating hormone (TSH) are related to HT-related thyroid tumors. (medsci.org)
  • Using a newly generated monoclonal antibody against Siglec-6 to detect protein expression, this latter study found that Siglec-6 was expressed by placental cytotrophoblasts and syncytiotrophoblasts as well as several human hematopoietic cell lines, including TF-1, HEL, U937, and THP-1 cells. (wikipedia.org)
  • This monoclonal antibody also bound to nearly all human peripheral blood B cells, although more recent reports have not replicated this finding. (wikipedia.org)
  • 1. Anti-human CD73 monoclonal antibody inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells. (nih.gov)
  • 9. Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies. (nih.gov)
  • The following product was used in this experiment: Pan Cytokeratin Monoclonal Antibody (AE1/AE3), eFluor™ 615, eBioscience™ from Thermo Fisher Scientific, catalog # 42-9003-82, RRID AB_10804663. (thermofisher.com)
  • Description: The monoclonal antibodies AE1 and AE3 recognize many of the acidic and basic cytokeratin family members. (thermofisher.com)
  • EXPERIMENTAL DESIGN: The human bladder cancer cell line T24 cells were used as immunogen to generate mouse monoclonal antibodies. (bvsalud.org)
  • The nuclear import of YAP was associated with a rapid decrease in YAP phosphorylation at Ser 127 and Ser 397 , sites targeted by LATS1/2 and with the expression of YAP-regulated genes, including connective tissue growth factor ( CTGF ), and cysteine-rich angiogenic inducer 61 (CYR61). (nih.gov)
  • We have developed a simple and sensitive enzyme-linked immunosorbent assay (ELISA) to quantify diphtheria and tetanus antigens in combined vaccine products and measure the degree of adsorption to adjuvant. (nih.gov)
  • In routine use as a consistency test for a pentavalent vaccine, the antigen ELISA has a geometric coefficient of variation (GCV) for total diphtheria antigen content of 12% compared to 39% for diphtheria potency (challenge assay, n=22) and a GCV of 7.3% for tetanus antigen content compared to 14.1% for potency (challenge assay, n=22). (nih.gov)
  • 16. Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function. (nih.gov)
  • Filter Recommendation: When using this eFluor® 615 antibody conjugate, we recommend a filter that will capture the 615 emission wavelength (for example, Excitation 560/55, 585LP, Emission 645/75). (thermofisher.com)
  • Applications Reported: This AE1/AE3 antibody has been reported for use in immunohistochemical staining, immunocytochemistry, immunohistochemical staining of frozen tissue sections, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections. (thermofisher.com)
  • We examined BCMab1 antigen expression in the patients with bladder cancer through immunohistochemical staining and investigated the BCMab1 antigen association with clinical severity. (bvsalud.org)
  • 18. A novel anti-Cyr61 antibody inhibits breast cancer growth and metastasis in vivo. (nih.gov)
  • 12] A sandfly endemic to parts of Brazil was found to have salivary protein that induces cross-reactive antibodies to pemphigus autoantigen desmoglein 1. (medscape.com)
  • Cluster analysis suggested that the expression of CYR61, EGR3, KLF6 and SNF1LK were upregulated in cancer tissue from hereditary cases, but we were not able to confirm this on the protein level, and levels of these proteins were not found to correlate with clinico-pathological characteristics or biochemical recurrence. (scirp.org)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ankyrin Repeat Domain Protein 1 (ANKRD1) in Tissue homogenates and other biological fluids. (worldcarecouncil.org)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Death Associated Protein Kinase 1 (DAPK1) in Tissue homogenates, cell lysates and other biological fluids. (kits-elisa.com)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Death Associated Protein Kinase 1 (DAPK1) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. (kits-elisa.com)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Internexin Neuronal Intermediate Filament Protein Alpha (INa) in Tissue homogenates, cell lysates and other biological fluids. (jemsec.com)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Internexin Neuronal Intermediate Filament Protein Alpha (INa) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. (jemsec.com)
  • Finally, higher Cyr61 levels were detected in the PDAC specimens from the patients with distal tumor metastasis, compared to PDAC without metastasis at diagnosis. (oncotarget.com)
  • Increased levels of anti-dsDNA antibodies in immune complexes before treatment with belimumab associate with clinical response in patients with systemic lupus erythematosus. (medscape.com)
  • Associations between certolizumab pegol serum levels, anti-drug antibodies and treatment response in patients with inflammatory joint diseases: data from the NOR-DMARD study. (medscape.com)
  • Association of HLA-te22 antigen with anti-nuclear antibodies in Chinese patients with erosive oral lichen planus. (ntu.edu.tw)
  • Using cluster analysis, four transcripts were found to be upregulated in hereditary prostate cancer tissue: CYR61, EGR3, KLF6 and SNF1LK. (scirp.org)
  • antibodies were not detected, and neurologic consultation identifi ed severe confusion, inatten- no treatment was instituted. (cdc.gov)
  • antibodies were not detected, and no treatment was instituted. (cdc.gov)
  • however, the inability of recombinant antigens to provide complete protection against pneumonic plague in animal models remains a significant concern. (frontiersin.org)
  • All animals had detectable neutralizing rabies virus antibody titers after vaccination, but one animal failed to meet the World Organization for Animal Health's definition for adequate vaccination (0.5 IU/ml), and two other animals had low antibody titers (0.56 and 0.6 IU/ml). (cdc.gov)