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  • enzymes
  • (aspetjournals.org)
  • These data demonstrate that resveratrol inhibits aryl hydrocarbon-induced CYP1A activity in vitro by directly inhibiting CYP1A1/1A2 enzyme activity and by inhibiting the signal transduction pathway that up-regulates the expression of carcinogen activating enzymes. (aspetjournals.org)
  • The active metabolite has a free thiol group, which interacts with zinc ions in the active site of class 1 and 2 HDAC enzymes, resulting in inhibition of its enzymatic activity. (drugbank.ca)
  • This study examines the possibility enzymes such as CYP1A1, which converts estrone to 2-hydroxyestrone 14 and ultimately results in metabolites that are antiproliferative and proapoptotic 15However, at doses promotes metabolically stressed cancer cells has been one report of effect from IndoleCarbinol was note. (cristaogospel.tk)
  • multiple
  • These non- BRCA1/2 breast cancer families (termed BRCAx families) comprise a histopathologically heterogeneous group, further supporting their origin from multiple genetic events. (pnas.org)