However, the risk of primary cancer clinically as an immunosuppressant maceutical drugs ciclosporin and in the transplant recipient increases to treat certain autoimmune diseas- azathioprine. (who.int)
Systemic1
Cyclosporine and systemic corticosteroids, but not antihistamines or omalizumab, are used less during the pandemic. (eur.nl)
Immunosuppressant2
The immunosuppressant cyclosporine (ciclosporin) may be recommended to increase tear production and, for short term use, topical corticosteroid medications are also sometimes helpful to reduce inflammation. (wikipedia.org)
The use of immunosuppressant medicines, including ciclosporin, during pregnancy has been shown to increase the risk of problems in the mother and the unborn child. (mydr.com.au)
To stratify patients with polymyositis/dermatomyositis-associated interstitial lung disease (ILD) who were initially treated with an intensive regimen consisting of high-dose corticosteroids, a calcineurin inhibitor, and intravenous cyclophosphamide (triple-combo therapy) into subgroups based on mortality outcomes by a cluster analysis using a large-scale multicenter retrospective cohort of Japanese patients with myositis-associated ILD (JAMI). (frontiersin.org)
Methotrexate1
Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (empr.com)
Restasis1
Your doctor may suggest drops that contain the immune-suppressing medication cyclosporine ( Restasis ) or corticosteroids. (healthline.com)
Ophthalmic emulsion1
Some believe off-label use of cyclosporine ophthalmic emulsion is helpful in managing the inflammatory and dry-eye components of the disease. (medscape.com)
Drugs of this class more expensive than topical corticosteroids. (medscape.com)
Topical cyclosporine has been our only FDA-approved, true antiinflammatory for DED and has appropriately become the mainstay of treating moderate and more severe DED. (crstoday.com)
This adjunctive therapy helps to rapidly reduce ocular surface inflammation, but of course, topical corticosteroids cannot be used safely long term due to the risk of elevated IOP, the development of cataracts, and the potentiation of infection. (crstoday.com)
Immunosuppressive agent1
The cluster model was further applied to 283 patients who received conventional regimens consisting of corticosteroids with or without a single immunosuppressive agent (dual-combo therapy or monotherapy). (frontiersin.org)
NSAIDs1
Member has had an inadequate response, intolerance, or contraindication to non-steroidal anti-inflammatory drugs (NSAIDs), colchicine and corticosteroids. (aetna.com)
Orphan1
The firm's AlloCol product, for immediate and controlled cyclosporine release, has been granted orphan drug designation by the FDA for the GvHD prevention and treatment indication. (genengnews.com)
Transplant3
APO-CICLOSPORIN is used for people who have had a kidney, heart or liver transplant, to prevent the body from rejecting the new organ. (mydr.com.au)
However, APO-CICLOSPORIN can be used in children younger than 16 who have had an organ transplant or who have nephrotic syndrome. (mydr.com.au)
A third Sigmoid clinical candidate, CyLow™, is an immediate-release cyclosporine for potential applications in the prevention of transplant rejection, and psoriasis, and has also undergone a Phase I pharmacokinetic study. (genengnews.com)
Drugs1
Corticosteroids and other immunosuppressive drugs have been attempted for the treatment of acute exacerbation, but only with very limited effectiveness. (go.jp)
Lesions1
More complicated cases with multiple lesions should be treated with corticosteroids, particularly with an intralesional injection of methylprednisolon. (wikipedia.org)
Pulmonary1
Corticosteroids also represent an option for pulmonary EG treatment. (wikipedia.org)
Formulation2
Lead candidate CyCol is a colon-targeted, nonsystemic formulation of cyclosporine, which is poised to start in Phase III studies in Europe and North America for inducing remission and the maintenance of remission in patients with moderate-to-severe ulcerative colitis. (genengnews.com)
The innovative galenical formulation developed by Sigmoid is suitable to improve patient outcomes and to avoid the use of biologics and corticosteroids. (genengnews.com)
Treatment2
Seven patients were received CsA (1.0-2.0 mg/kg per day) after the treatment with corticosteroids. (go.jp)
First-line treatment appears to be corticosteroid therapy. (nih.gov)
Medicines2
Many other medicines may be affected by APO-CICLOSPORIN or they may affect how well APO-CICLOSPORIN works. (mydr.com.au)
It is used with ciclosporin and corticosteroids (other medicines used to prevent organ rejection). (europa.eu)
Inflammation1
Corticosteroids are immunosuppressive and affect the replication, movement, and activity of virtually all cells involved with inflammation. (medscape.com)
Clinical1
Corticosteroids have been used for all of the various clinical manifestations of Behçet disease. (medscape.com)
The purpose of this study is to evaluate the effect of two different doses of ianalumab versus placebo in addition to first-line corticosteroids in maintaining platelet count ≥30 G/L in adult participants with primary ITP. (centerwatch.com)
Disease2
Cyclosporine is a cyclic polypeptide that suppresses some humoral immunity and, to a greater extent, cell-mediated immune reactions such as delayed hypersensitivity, allograft rejection, experimental allergic encephalomyelitis, and graft versus host disease for a variety of organs. (medscape.com)
Dr. Falk Pharma is making an equity investment in Irish firm Sigmoid Pharma as part of an exclusive license, development, and option deal centered on developing Sigmoid's Single-Multi Pill (SmPill ® ) cyclosporine products, including its lead firm's CyCol ® and AlloCol ® candidates, for indications including graft versus host disease (GvHD), ulcerative colitis, and other gastrointestinal diseases, in Europe. (genengnews.com)
Affect1
Breast-feeding is not recommended since ciclosporin, the active ingredient in APO-CICLOSPORIN, passes into breast milk and may affect your baby. (mydr.com.au)
Improve1
Ursula Falk, M.D., managing director at Dr. Falk Pharma, added, "Colon-targeted cyclosporine promises to improve the benefit/risk ratio of this molecule and holds great potential in the management of ulcerative colitis. (genengnews.com)