A tacrolimus test system is a device intended to quantitatively determine tacrolimus concentrations as an aid in the management of transplant patients receiving therapy with this drug. (medicregister.com)
The objectives of the present study were to 1) develop a sandwich time-resolved fluorescenceimmunoassay (TRFIA) with higher detectability to measure blood INSL3 concentrations in female cattle, 2) determine INSL3 concentrations in female cattle among age groups and reproductive conditions, and 3) explore associations between INSL3 levels and ultrasonographic ovarian measurements. (bvsalud.org)
Patient1
Blood from a patient flows through the tubing of the extracorporeal blood system and accessories to the blood compartment of the dialyzer, then returns through further tubing of the extracorporeal blood system to the patient. (medicregister.com)
Gengraf6
Gengraf ® Oral Solution (cyclosporine oral solution, USP [MODIFIED]) has increased bioavailability in comparison to Sandimmune ® Oral Solution (cyclosporine oral solution, USP). (nih.gov)
Cyclosporine blood concentrations should be monitored in transplant and rheumatoid arthritis patients taking Gengraf ® to avoid toxicity due to high concentrations. (nih.gov)
Cyclosporine, the active ingredient in Gengraf ® , in recommended dosages, can cause systemic hypertension and nephrotoxicity. (nih.gov)
Gengraf ® Oral Solution (cyclosporine oral solution, USP [ MODIFIED ]) is a modified oral formulation of cyclosporine that forms an aqueous dispersion in an aqueous environment. (nih.gov)
Cyclosporine, the active principle in Gengraf ® Oral Solution, is a cyclic polypeptide immunosuppressant agent consisting of 11 amino acids. (nih.gov)
Gengraf ® Oral Solution (cyclosporine oral solution, USP [ MODIFIED ]) is available in 50 mL bottles. (nih.gov)
Renal function1
Renal dysfunction, including structural kidney damage, is a potential consequence of cyclosporine, and therefore, renal function must be monitored during therapy. (nih.gov)
During maintenance treatment, teicoplanin trough serum concentrations monitoring may be performed at least once a week to ensure that these concentrations are stable. (medicines.org.uk)
Measurement1
15. Wright JD, Boudinot FD, Ujhelyi MR. Measurement and analysis of unbound drug concentrations. (frojeostern.com)
Exposure1
Optimal ciclosporin A (CsA) exposure in kidney transplant recipients is difficult to attain because of variability in CsA pharmacokinetics. (nih.gov)
Kidney1
De novo kidney transplant patients (n = 33) were treated with CsA for 1 year and extensive blood sampling was performed on multiple occasions throughout the year. (nih.gov)
Reversible1
The effectiveness of cyclosporine results from specific and reversible inhibition of immunocompetent lymphocytes in the G 0 - and G 1 -phase of the cell cycle. (nih.gov)
Dose3
Dose adjustments should be made in transplant patients to minimize possible organ rejection due to low concentrations. (nih.gov)
The risk increases with increasing dose and duration of cyclosporine therapy. (nih.gov)
The effects of the non-genetic covariates hematocrit, serum albumin concentration, cholesterol, demographics (i.e., body weight), CsA dose interval, prednisolone dose and genetic polymorphisms in genes encoding ABCB1, CYP3A4, CYP3A5, and PXR on CsA pharmacokinetics were studied using non-linear mixed effect modeling. (nih.gov)
Liver1
Also, MELD score employs serum creatinine as a variable, and it is known that end stage liver disease patient with AKI is more likely to receive a higher priority in transplantation list based on MELD score [ 20 ]. (biomedcentral.com)