Cyclooxygenase 2 inhibitor induces apoptosis. Medical search. Frequent questions

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Anatomy26

Cell Line, Tumor Cells, Cultured Tumor Cells, Cultured Mitochondria Cell Line Jurkat Cells HL-60 Cells Endothelium, Vascular Seminal Vesicles Epithelial Cells Fibroblasts Macrophages HeLa Cells U937 Cells Cell Nucleus Muscle, Smooth, Vascular HT29 Cells Intestinal Mucosa T-Lymphocytes Blood Platelets Neutrophils Cell Line, Transformed Endothelial Cells Gastric Mucosa Cytosol Neurons

Organisms9

Rats, Sprague-Dawley Mice, Inbred C57BL Mice, Knockout Rats, Wistar Mice, Nude Mice, Transgenic Mice, Inbred BALB C Sheep Rabbits

Diseases4

Necrosis Disease Models, Animal Colonic Neoplasms Inflammation

Chemicals and Drugs163

Cyclooxygenase 2 Cyclooxygenase 1 Cyclooxygenase Inhibitors Cyclooxygenase 2 Inhibitors Prostaglandin-Endoperoxide Synthases Caspases Apoptosis Regulatory Proteins Dinoprostone Indomethacin Caspase 3 Proto-Oncogene Proteins c-bcl-2 Inhibitor of Apoptosis Proteins Isoenzymes Prostaglandins Arachidonic Acid bcl-2-Associated X Protein X-Linked Inhibitor of Apoptosis Protein Sulfonamides Anti-Inflammatory Agents, Non-Steroidal Nitrobenzenes Membrane Proteins Apoptosis Inducing Factor Lipoxygenase Inhibitors Pyrazoles CASP8 and FADD-Like Apoptosis Regulating Protein Caspase 9 Ibuprofen Caspase Inhibitors Enzyme Inhibitors Caspase 8 Tumor Suppressor Protein p53 Thromboxane B2 Fas Ligand Protein Cytochromes c Arachidonic Acids RNA, Messenger bcl-X Protein Flurbiprofen Lipoxygenase Annexin A5 Masoprocol Eicosanoids Antineoplastic Agents 6-Ketoprostaglandin F1 alpha Aspirin Epoprostenol Proto-Oncogene Proteins Amino Acid Chloromethyl Ketones Reactive Oxygen Species Cysteine Proteinase Inhibitors Tumor Necrosis Factor-alpha NF-kappa B Poly(ADP-ribose) Polymerases RNA, Small Interfering Piroxicam Diclofenac Nitric Oxide TNF-Related Apoptosis-Inducing Ligand Thromboxane A2 Intramolecular Oxidoreductases Receptors, Prostaglandin E Arachidonate 5-Lipoxygenase Caspase 7 Thromboxane-A Synthase Naproxen Hydroxyeicosatetraenoic Acids Thiazines Membrane Glycoproteins Thromboxanes Meclofenamic Acid Sulfones Proto-Oncogene Proteins c-akt Prostaglandins G bcl-2 Homologous Antagonist-Killer Protein Sulindac Cytochrome c Group Nitric Oxide Synthase Lactones Dinoprost Myeloid Cell Leukemia Sequence 1 Protein BH3 Interacting Domain Death Agonist Protein 5,8,11,14-Eicosatetraynoic Acid Mitogen-Activated Protein Kinases p38 Mitogen-Activated Protein Kinases 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine Protein-Serine-Threonine Kinases Staurosporine Ceramides Neoplasm Proteins Phospholipases A Carrier Proteins Hydrogen Peroxide bcl-Associated Death Protein Phospholipases A2 Prostaglandins E Prostaglandin D2 Antineoplastic Agents, Phytogenic Receptors, TNF-Related Apoptosis-Inducing Ligand Lipopolysaccharides Caspase 2 Nitric Oxide Synthase Type II Fas-Associated Death Domain Protein DNA-Binding Proteins Prostaglandin H2 Leukotrienes Receptors, Tumor Necrosis Factor 8,11,14-Eicosatrienoic Acid Cysteine Endopeptidases Interleukin-1 Apoptotic Protease-Activating Factor 1 Cycloheximide Intracellular Signaling Peptides and Proteins Thiazoles Recombinant Proteins Ketorolac Calcimycin Transcription Factors Receptors, Prostaglandin E, EP4 Subtype Arachidonate Lipoxygenases Antioxidants Receptors, Thromboxane Imidazoles Flavonoids Bradykinin Leukotriene B4 Caspase 1 Phosphatidylinositol 3-Kinases Salicylates Proteins Receptors, Prostaglandin E, EP1 Subtype Hydrazines Cyclin-Dependent Kinase Inhibitor p21 Culture Media, Serum-Free Oligopeptides Prostaglandin Antagonists NG-Nitroarginine Methyl Ester Etoposide MAP Kinase Kinase Kinase 5 Anticarcinogenic Agents Plant Extracts Prostaglandins H Tumor Suppressor Proteins Calcium Receptors, Prostaglandin E, EP2 Subtype DNA Primers Indoles Pyridines Oligonucleotides, Antisense Tolmetin Peroxidases Tetrazolium Salts Nuclear Proteins 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid Anti-Inflammatory Agents Acetylcysteine Cytokines Propidium Nitric Oxide Donors Glutathione Receptors, Prostaglandin Receptors, Death Domain DNA Dactinomycin

Analytical, Diagnostic and Therapeutic Techniques and Equipment13

In Situ Nick-End Labeling Blotting, Western Flow Cytometry Transfection Reverse Transcriptase Polymerase Chain Reaction Immunohistochemistry Disease Models, Animal Models, Biological Immunoblotting Xenograft Model Antitumor Assays Drug Screening Assays, Antitumor Culture Media, Serum-Free Microscopy, Fluorescence

Phenomena and Processes39

Apoptosis DNA Fragmentation Signal Transduction Cell Survival Enzyme Activation Dose-Response Relationship, Drug Cell Proliferation Cell Cycle Cell Division Transfection Up-Regulation Time Factors Down-Regulation Phosphorylation Cell Death Membrane Potential, Mitochondrial Gene Expression Regulation, Enzymologic Drug Synergism Genes, bcl-2 Oxidative Stress Gene Expression Regulation, Neoplastic Gene Expression Gene Expression Regulation Necrosis Enzyme Induction DNA Damage Vasodilation RNA Interference Protein Binding Mutation Vasoconstriction Kinetics Cell Differentiation Base Sequence Drug Resistance, Neoplasm MAP Kinase Signaling System Transcription, Genetic Amino Acid Sequence Cytoprotection

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Cyclooxygenase 2 Cyclooxygenase 1 Cyclooxygenase Inhibitors Cyclooxygenase 2 Inhibitors Prostaglandin-Endoperoxide Synthases Apoptosis Caspases Apoptosis Regulatory Proteins Dinoprostone Indomethacin Caspase 3 Proto-Oncogene Proteins c-bcl-2 Inhibitor of Apoptosis Proteins Isoenzymes Prostaglandins DNA Fragmentation Arachidonic Acid Cell Line, Tumor bcl-2-Associated X Protein In Situ Nick-End Labeling Cells, Cultured X-Linked Inhibitor of Apoptosis Protein Signal Transduction Cell Survival Sulfonamides Anti-Inflammatory Agents, Non-Steroidal Nitrobenzenes Membrane Proteins Apoptosis Inducing Factor Lipoxygenase Inhibitors Pyrazoles CASP8 and FADD-Like Apoptosis Regulating Protein Enzyme Activation Caspase 9 Ibuprofen Caspase Inhibitors Blotting, Western Tumor Cells, Cultured Enzyme Inhibitors Mitochondria Caspase 8 Tumor Suppressor Protein p53 Dose-Response Relationship, Drug Thromboxane B2 Fas Ligand Protein Cell Line Cytochromes c Cell Proliferation Arachidonic Acids RNA, Messenger bcl-X Protein Flurbiprofen Lipoxygenase Annexin A5 Masoprocol Eicosanoids Antineoplastic Agents 6-Ketoprostaglandin F1 alpha Aspirin Flow Cytometry Cell Cycle Epoprostenol Proto-Oncogene Proteins Amino Acid Chloromethyl Ketones Reactive Oxygen Species Cell Division Cysteine Proteinase Inhibitors Tumor Necrosis Factor-alpha Transfection Reverse Transcriptase Polymerase Chain Reaction Up-Regulation Rats, Sprague-Dawley NF-kappa B Time Factors Poly(ADP-ribose) Polymerases Mice, Inbred C57BL Down-Regulation RNA, Small Interfering Piroxicam Jurkat Cells HL-60 Cells Immunohistochemistry Phosphorylation Diclofenac Nitric Oxide TNF-Related Apoptosis-Inducing Ligand Thromboxane A2 Intramolecular Oxidoreductases Receptors, Prostaglandin E Cell Death Mice, Knockout Arachidonate 5-Lipoxygenase Caspase 7 Thromboxane-A Synthase Membrane Potential, Mitochondrial Naproxen Endothelium, Vascular Hydroxyeicosatetraenoic Acids Gene Expression Regulation, Enzymologic Drug Synergism

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