Cyclizes. Medical search. Frequent questions

The most likely reason is that there is no good way to cyclize the other two linear peptides. (rosettacommons.org)
That being said, there are many ways of cyclizing peptides, and to my knowledge, Peptiderive uses a very narrow definition of "compatible with cyclic geometry": it only considers cyclization schemes involving disulfides between terminal residues of linear peptides when the terminal residues are already close enough to gether to make disulfide closure likely. (rosettacommons.org)

The enzyme protoaphin-aglucone dehydratase (cyclizing) (EC 4.2.1.73) catalyzes the chemical reaction protoaphin aglucone ⇌ {\displaystyle \rightleftharpoons } xanthoaphin + H2O This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. (wikipedia.org)
Upon longer reaction, [M+H]+ ions with greater retention times and the 558.17 m/z expected for mono(GSH)-MDI reaction products were observed, and exhibited MS/MS collision-induced dissociation (CID)-fragmentation patterns consistent with cyclized structures. (cdc.gov)
Compared with 4,4' MDI, 2,2' and 2,4' isomers exhibit similar rapid reactivity with GSH and formation of bis(GSH)-MDI conjugates, but greater formation of cyclized mono(GSH) conjugates following extended reaction times (10 minutes to 2 hours). (cdc.gov)
Their distinct biosynthetic activity includes an endoperoxidase synthase reaction that oxygenates and cyclizes polyunsaturated fatty acid precursors (eg, arachidonic acid) to form prostaglandin G 2 (PGG2), and a peroxidase reaction that converts PGG2 to prostaglandin H 2 (PGH2), as shown below. (medscape.com)

The 414K-MDI conjugation appears to covalently cross- link GSH to albumin via GSH's NH2-terminus, a unique conformation possibly resulting from cyclized mono(GSH)-MDI or asymmetric ( S , N -linked) bis(GSH)-MDI conjugates. (cdc.gov)

Further, we determine that under aerobic, but not anaerobic, conditions the Gly-Gly-Gly chromophore sequence cyclizes and incorporates an oxygen atom. (proteopedia.org)
The inhibitor was designed by fusing together a pair of reactive loops based on a sequence derived from SFTI-1 to create a backbone-cyclized disulfide-bridged 16-mer peptide. (rcsb.org)

To cyclize something is to have it form rings. (wallacewiki.com)
Xylamine (N-2'-chloroethyl-N-ethyl-2-methylbenzylamine), a nitrogen mustard that irreversibly inhibits norepinephrine uptake, cyclizes in solution to form an aziridinium ion. (aspetjournals.org)

Also disproportionates linear maltodextrins without cyclizing (cf. (cathdb.info)

Cerezo, A.S. 'Antiherpetic and anticoagulant properties of carrageenans from the red seaweed Gigartina skottsbergii and their cyclized derivatives: Correlation between structure and biological activity' (1997) International Journal of Biological Macromolecules. (uba.ar)

Other names in common use include protoaphin dehydratase, protoaphin dehydratase (cyclizing), and protoaphin-aglucone hydro-lyase (cyclizing). (wikipedia.org)

10 ). A mixture of CBTE2A-CCMSH(Arg 11 ) and trichlorooxobis-(triphenylphosphine)-rhenium (1:1 molar ratio) was incubated for 3 h at 25°C. The cyclized peptide, CBTE2A-ReCCMSH(Arg 11 ), was purified with high-performance liquid chromatography (HPLC). (nih.gov)

Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity. (neurotree.org)
Furthermore, we show that Sortase A can be used to sequence-specifically ligate eGFP to amino-terminated poly(ethylene glycol) and to generate protein oligomers and cyclized monomers using suitably tagged eGFP. (nih.gov)

The intermediate imine then undergoes a 6- endo cyclization to furnish the cyclized product, tetrahydro-β-carboline [10] . (beilstein-journals.org)
86 The critical reagent is titanium(IV) chloride, which appears to serve as a strong dehydrating agent to promote formation of a putative Schiff base intermediate that may subsequently cyclize to the desired product. (nih.gov)
Iso-E Super¤ is produced commercially by Diels-Alder condensation of -myrcene with 3-methyl-3-pentene-2-one in the presence of aluminum chloride to give a monocyclic intermediate that is cyclized in the presence of 85% phosphoric acid. (nih.gov)

Mechanistic studies utilizing dienophiles suggest that the previously described cyclized products have originated from Michael addition reactions. (vt.edu)

To cyclize something is to have it form rings. (wallacewiki.com)
A group of DITERPENES cyclized into four rings. (nih.gov)
SESQUITERPENES cyclized into two adjoining cyclohexane rings but with a different configuration from the ARTEMISININS . (nih.gov)