• We described the anticancer effects and mechanism of action of HL2401, a monoclonal antibody directed at CXCL1 with in vitro and in vivo data on bladder and prostate cancers. (thno.org)
  • Targeting these critical interactions with a CXCL1 monoclonal antibody offers a novel strategy to therapeutically manage bladder and prostate cancers. (thno.org)
  • Anti-Podoplanin antibody Antibody-drug conjugates (ADCs), which encompass a monoclonal antibody (mAb), a linker, and a payload, can ship a drug to most cancers tissues. (elisastrip.com)
  • Previous studies have established the efficacy of novel antibody-drug conjugates (ADCs) in treating HER2-low tumors [ 7 , 8 ]. (e-crt.org)
  • polymere-drug conjugates for the treatment of cancer: HPMA-copolymer-bound doxorubicin and cytarbine, unmodified or conjugated with monoclonal antibodies for targeted drug delivery. (cuni.cz)
  • Methods Defining mobile islands mapped to any damage from the three monomers of the Imd pathway through cyclin D1 targeting. (aiklf.com)
  • We identified both gene and protein markers for three temporally distinct ProSG cell subsets, including a migratory cell population with a transcriptome distinct from the previously defined T1- and T2-ProSG stages. (biologists.com)
  • Cyclin-dependent kinase (CDK) 10, is reported to play an essential role in the progression from the G2 to M phase of the cell cycle. (jcancer.org)
  • Mitosis is directly linked to RHAMM by suppressing cell cycle-dependent kinase (Cdc2) and cyclin B1 expression. (medscape.com)
  • Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II) (PubMed:9499409, PubMed:15563843). (nih.gov)
  • These results strongly suggest that M‐H1K consists of cdc2 kinase forming a complex with cyclin B, and that cdk2 kinase is not a component of M‐H1K, although it is found in the highly purified M‐H1K. (elsevierpure.com)
  • 53% of the patients had sufficient archived pathologic specimens for incorporation into a tissue microarray for immunohistochemical analysis for cyclophilin B, cyclin D1, p21, hypoxia-inducible factor-1α (HIF-1α), carbonic anhydrase, and major vault protein. (nih.gov)
  • 16. [Effect of cyclin D1 protein expression on the prognosis of esophageal squamous-cell carcinoma treated with preoperative radiotherapy]. (nih.gov)
  • 18. Inverse correlation of aberrant expression of fragile histidine triad (FHIT) protein with cyclin D1 protein and prognosis in Chinese patients with cholangiocarcinoma. (nih.gov)
  • 12. Immunohistochemical analysis with multiple antibodies in search of prognostic markers for clear cell renal cell carcinoma. (nih.gov)
  • Utilize our Cyclin E1 antibodies in your research endeavors for dependable Cyclin E1 detection. (antibodies-online.com)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Eosinophil Chemotactic Factor (ECF) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. (agctsequencing.com)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Eosinophil Chemotactic Factor (ECF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species. (agctsequencing.com)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Metallothionein 2 (MT2) in serum, plasma, tissue homogenates and other biological fluids. (agctsequencing.com)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Metallothionein 2 (MT2) in samples from Serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species. (agctsequencing.com)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Plasminogen Activator, Urokinase (uPA) in serum, plasma and other biological fluids. (bestpractice-life.pl)
  • The cyclin gene family has undergone a massive expansion in angiosperm plants, but only a few cyclins were thoroughly characterized. (prolekarniky.cz)
  • Expression analysis showed that exposure of cells to DMA III resulted in a gene profile different from that in cells exposed to iAs III or MMA III , and that the iAs III -induced gene profile was closest to that in the tumorigenic HUC-1-derived 3-methylcholanthrene-induced tumorigenic cell line MC-SV-HUC T2, which was derived from SV-HUC-1 cells by methylcholanthrene treatment. (nih.gov)
  • Cyclin-dependent kinases (CDKs) and cyclins represent an ancient molecular module that drives and regulates cell cycle progression. (prolekarniky.cz)
  • Brain MRI showed progression of lesions visualized on T2 and fluid-attenuated inversion recovery sequences and an increased apparent diffusion coefficient signal, appropriate for vasogenic edema (Appendix Shape 1). (baxkyardgardener.com)
  • Many of these cyclins exhibit cell-type-specific expression in vegetative tissues and distinct subcellular localization. (prolekarniky.cz)
  • Our phenotypic and expression data provide extensive evidence that multiplication of cyclins is in plants accompanied by functional diversification. (prolekarniky.cz)
  • 2. Expression of epidermal growth factor receptor and cyclin D1 in pretreatment biopsies as a predictive factor of radiotherapy efficacy in early glottic cancer. (nih.gov)
  • 19. [Expression of cyclin D1 in brain gliomas and its significance]. (nih.gov)
  • 1. Association between high initial tissue levels of cyclin d1 and recurrence of nasopharyngeal carcinoma. (nih.gov)
  • The data was further validated using specific antibodies to 4 proteins (CA2, GS, CKMT and CRMP2) by western blot (WB) in the same samples used for 2D-DIGE, with additional confirmation by immunohistochemitsry (IHC) using frontal lobe tissue from different HAD and HIV+ non-dementia patients. (biomedcentral.com)
  • This shows that there is strong IgG antibody production against RHAMM in leukemia patients that is not due to autoimmunity. (medscape.com)
  • AB - Antibodies against hepatitis E virus (anti-HEV) were found in 248 Swedish and Danish patients between 1993 and 2007. (nih.gov)
  • Find Cyclin E1 Antibodies with a specific Host. (antibodies-online.com)
  • Find Cyclin E1 Antibodies with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. (antibodies-online.com)
  • [ 27 ] Lysis of autologous AML blasts, dendritic cells (DCs) generated from autologous AML blasts and RHAMM-R3-pulsed T2 cells was MHC class I-restricted and epitope-specific, as demonstrated in antibody-blocking and cross-priming experiments. (medscape.com)
  • Type 2 Diabetes Mellitus (T2-DM) is a heterogeneous and complex process comprising multiple pathogenic factors [2] and multi-organs complications' that remain as a challenge for scientists and clinicians. (oatext.com)
  • is seen as a an auto-antibody [5] which can agglutinate red bloodstream cells (RBCs) in temperatures less than Z-360 calcium salt (Nastorazepide calcium salt) that of your body, also to activate the supplement program in charge of lysis of RBCs subsequently. (immune-source.com)
  • CAD is normally seen as a an auto-antibody [5] which can agglutinate red bloodstream cells (RBCs) at temperature ranges less than that of your body, and eventually to activate the supplement system in charge of lysis of RBCs. (immune-source.com)
  • Complete blood count and flow cytometry revealed lymphopenia affecting all lymphocyte subsets (280 CD4+ cells/L, 80 CD8+ cells/L, 30 CD19+ cells/L). Brain magnetic resonance imaging (MRI) showed T2-weighted hyperintense, nonenhancing, multifocal white matter lesions (Appendix Physique 1). (baxkyardgardener.com)
  • Mutant analysis revealed that these cyclins contribute to distinct meiosis-related processes. (prolekarniky.cz)
  • Analysis of plants carrying cyclin SDS with an introduced D-box motif determined that, in addition to its function in recombination, SDS acts together with CYCB3;1 in suppressing unscheduled cell wall synthesis. (prolekarniky.cz)
  • The cell pellets were resuspended in 100?l PBS supplemented with 5?l antibodies against Compact disc29 (Abcam, UK), Compact disc105, Compact disc34 and Compact disc73 (AbdSerotec, UK), SSEA4 Angiotensin 1/2 + A (2 - 8) and CD90 (eBiosciences, USA) for 30?min in room temperature, before two PBS flow\cytometry and washes analysis. (angiogenesis-blog.com)
  • This antibody can cross react with MAP1LC3A, MAP1LC3B, and MAP1LC3C. (thermofisher.com)
  • While A2 cyclins are important for chromosome segregation, CYCB3;1 prevents ectopic cell wall formation. (prolekarniky.cz)
  • 3. Cyclin d1 is a valuable prognostic marker in oropharyngeal squamous cell carcinoma. (nih.gov)
  • 6. p53 and cyclin D1 as prognostic factors in squamous cell carcinoma of the larynx. (nih.gov)
  • 17. Image cytometry of cyclin D1: a prognostic marker for head and neck squamous cell carcinomas. (nih.gov)
  • In this study we performed a systematic immunolocalization screen to identify Arabidopsis thaliana A- and B-type cyclins expressed in meiosis. (prolekarniky.cz)
  • We found six A-type cyclins and a single B-type cyclin (CYCB3;1) to be expressed in male meiosis. (prolekarniky.cz)
  • 4. Adjuvant fractionated high-dose-rate intracavitary brachytherapy after external beam radiotherapy in Tl and T2 nasopharyngeal carcinoma. (nih.gov)
  • Additionally it is important to remember that agglutination isn't necessary for supplement activation, specifically in sufferers with high degrees of auto-antibodies (wide thermal selection of frosty agglutinins) [7,8]. (immune-source.com)