Current approaches to fungal pathogenesis. Medical search. Frequent questions

Fungal nail infections, also known as "onychomycosis," are very common. (cdc.gov)
Fungal toenail infections are more common than fungal fingernail infections. (cdc.gov)
Most fungal nail infections are not serious. (cdc.gov)
People who have fungal toenail infections often have a fungal skin infection on the foot, especially between the toes (commonly called athlete's foot , ringworm on the foot, or tinea pedis). (cdc.gov)
Fungal nail infections are caused by many different types of fungi that live in the environment. (cdc.gov)
Who gets fungal nail infections? (cdc.gov)
Fungal infections are not the only possible cause of nail problems. (cdc.gov)
Other conditions can look similar to fungal nail infections. (cdc.gov)
Fungal nail infections can be difficult to cure, and treatment is most successful when started early. (cdc.gov)
Fungal nail infections typically don't go away on their own, and the best treatment is usually prescription antifungal pills taken by mouth. (cdc.gov)
Fungal nail infections can be closely associated with fungal skin infections. (cdc.gov)
Patients should discuss all skin concerns with their healthcare provider to ensure that all fungal infections are properly treated. (cdc.gov)
Even after treatment, fungal nail infections can come back. (cdc.gov)
Molecular testing, including polymerase chain reaction (PCR) testing, may be used to diagnose fungal nail infections. (cdc.gov)
The study's primary goal was to determine if species identification by semi-nested PCR (sn-PCR) with primers for the five most prevalent Candida species is sufficient to deal with the current trends of Candida infections in cancer patients. (bvsalud.org)
BACKGROUND: Neutropenia is the most important cause of life-threatening invasive fungal infections (IFIs). (bvsalud.org)
My lab is interested in understanding the role of subclinical fungal infections in asthma and their potential contribution to the high prevalence of asthma in urban areas. (einsteinmed.edu)
Fungal infections associated with the diseased cells were not seen. (peerj.com)
Their enhanced susceptibility to fungal infections may be explained by the lack of NETs, as hyphae of Candida species escape phagocytosis due to their size and require NETs for clearance. (silverchair.com)
understand our fungal our the Document to your loss, strongly not as many patients on our latest career, events near you and zone infections. (plywoodskyscraper.com)
Host immunity was believed to be the main factor responsible for the establishment of opportunistic fungal infections caused by yeast pathogens. (biomedcentral.com)
Candida species cause common oral fungal infections in human beings (1). (bvsalud.org)

Monocytes and their derivatives, including macrophages and dendritic cells, play diverse roles in the response to fungal pathogens. (frontiersin.org)
Many of the pathogens highlighted in the current issue of Emerging Infectious Diseases can collectively be described as low-incidence, high-consequence pathogens. (cdc.gov)
For intracellular human fungal pathogens such as Candida glabrata , an effective metabolic adaptation strategy is often required for survival and pathogenesis. (biomedcentral.com)
These opportunistic fungal pathogens may colonize, invade and induce lesions in any part of the oral cavity in both immunocompetent and immunocompromised individuals. (bvsalud.org)
Streptococcal pathogens continue to evade concerted efforts to decipher clear-cut virulence mechanisms, although numerous genes have been implicated in pathogenesis. (cdc.gov)

Candida albicans is the most important opportunistic fungal pathogen of humans. (ncl.edu.tw)
Surprisingly, it has been reported that engulfed C. glabrata are able to survive in this harsh microenvironment, further suggesting alternative carbon metabolism as a potential strategy for this opportunistic fungal pathogen to persist in the host. (biomedcentral.com)

However, in typical current clinical practice, one pathogen responsible for the disease is identified and targeted for treatment with more or less specific antimicrobial drugs. (asmblog.org)

Common bunt, caused by two fungal species, Tilletia caries and Tilletia laevis , is one of the most potentially destructive diseases of wheat. (mdpi.com)
EOS pathogenesis predominantly occurs by ascending colonization and infection of the uterine compartment and fetus with microbial species from the maternal genitourinary flora during labor and/or during vaginal delivery. (mhmedical.com)

Ave1 activates Ve1-mediated resistance and contributes to fungal virulence. (uu.nl)

Examination of nail clippings with a PAS stain can confirm the diagnosis of a fungal nail infection. (cdc.gov)
Further investigations using an integrated approach are needed to carry out the complete diagnosis of these diseases. (peerj.com)
To describe the general principles of the transmission, pathogenesis, and diagnosis of tuberculosis. (cdc.gov)
The approach to diagnosis of tuberculosis follows from the concepts of its pathogenesis. (cdc.gov)
To provide a classification scheme for tuberculosis that is based on pathogenesis, is consistent with current chemotherapeutic and chemopreventive recommendations, and is applicable to all in whom the diagnosis is or should be considered. (cdc.gov)
This article discusses the diagnosis and current management techniques for vesical calculus disease. (medscape.com)
However, current methods of faecal sampling in a rural setting for diagnosis are not consistently sufficient for the preservation of Salmonella spp. (imperial.ac.uk)
Our article summarizes these new advances in the diagnosis of HLH and includes a review of clinical findings, updated understanding of the pathogenesis, and promising new testing methods. (medscape.com)

How does someone get a fungal nail infection? (cdc.gov)
Anyone can get a fungal nail infection. (cdc.gov)
Occasionally, a bacterial infection can occur on top of a fungal nail infection and cause serious illness. (cdc.gov)
If a fungal infection is not treated, it can spread from one place to the other. (cdc.gov)
This is more common in people who have conditions like diabetes that make them more likely to get a fungal nail infection. (cdc.gov)
Down-regulation of Spds in the mutant altered overall nitrogen metabolism and significantly reduced fungal growth, pathogenicity, and the production of aflatoxins during maize seed infection. (usda.gov)
Current studies underway include a characterization of chitinase expression among asthmatics and a comparison of cryptococcal infection prevalence among asthmatics and non-asthmatics. (einsteinmed.edu)
The major risk factors for development of HCC include chronic hepatitis B (HBV) and hepatitis C virus infection, high dietary exposure to fungal aflatoxins, and other disorders causing cirrhosis, such as hereditary hemochromatosis, α 1 -antityripsin deficiency, primary biliary cirrhosis, non-alcoholic steatohepatitis and alcoholic cirrhosis [ 2 ]. (biomedcentral.com)
Clinical risk factors for EOS include those factors that provide opportunity for this pathogenesis (such as preterm and/or prolonged rupture of membranes [ROM]) or reflect progressive maternal inflammation and infection (such as maternal fever). (mhmedical.com)
Although the pathogenesis of EOS primarily occurs during labor and delivery for term infants, rarely intraamniotic infection may occur prior to the onset of labor and may even cause stillbirth. (mhmedical.com)

Research is focused on studying the molecular mechanisms involved in the pathogenesis of Vibrio cholerae , the bacterium that causes cholera, and Francisella tularensis , the bacterium that causes tularemia. (utsa.edu)
Animal experimentation directed at understanding the mechanisms and variables related to fungal induced asthma are also underway. (einsteinmed.edu)
Over the past few decades, multiple approaches have been used to explore the mechanisms of liver carcinogenesis. (biomedcentral.com)

EMA is considering a web-based approach to providing interpretive criteria (breakpoints) for susceptibility testing that sounds a lot like the approach FDA has taken with its susceptibility testing website (the website is here and a newsletter on it is here ). (amr.solutions)
Although their role in the pathogenesis is unclear, this suggests that disease increases CCA susceptibility to bioerosion. (peerj.com)

Fungal colonization of fiberglass insulation in the air distribution system of a multi-story office building: VOC production and possible relationship to a sick building syndrome. (cdc.gov)

Biofilms were stained with SYTO 9 ( green , live bacteria), FUN-1 (intracellular red , live fungal cells), calcofluor white ( blue , fungal cell wall). (asmblog.org)

This review will highlight the roles of monocytes in the immune response to some of the major fungi that cause invasive human disease, including Aspergillus, Cryptococcus, Candida, Histoplasma, Blastomyces , and Coccidioides , and discuss potential strategies to manipulate monocyte responses in order to enhance anti-fungal immunity in susceptible hosts. (frontiersin.org)

Considering evidence from Candida albicans and Saccharomyces cerevisiae , this review summarizes the current knowledge of the glyoxylate cycle as an alternative carbon metabolic pathway of C. glabrata . (biomedcentral.com)

A Novel Therapeutic Approach in Acute Respiratory Distress Syndrome? (silverchair.com)
This paper mainly reviews the clinical features, pathogenesis, and therapeutic strategies of neurologic ir-AEs. (hindawi.com)
thus, there is an urgent need to improve the current diagnostic and therapeutic options for better management of fungal BSIs [ 16 ]. (biomedcentral.com)

Current Opinion in Microbiology, 43, 162-168. (usim.edu.my)

This article discusses the alloimmune-dependent and -independent risk factors for bronchiolitis obliterans, the current understanding of the pathogenesis of bronchiolitis obliterans based on results of animal and human studies, the clinical staging of the complication, strategies that may contribute to the prevention and/or early detection of bronchiolitis obliterans, and suggestions for future research. (ersjournals.com)
The clinical principles of prevention, treatment, and holistic management of TB need to be an essential part of care for young adults in AfricaWhat are the current challenges in the management of tuberculosis in patients with co-occurring lung diseases? (medicalexaminationhelp.com)

New approaches are being undertaken to control these WHO priority organisms such as genome mining approach, one strain-many compound approach, repurposing of old drugs, phage therapy, usage of immunobiotics and probiotics. (benthambooks.com)
Polyamines (PAs) are ubiquitous polycations that influence normal growth, development, and stress responses in living organisms and have been shown to play a significant role in fungal pathogenesis. (usda.gov)

Chapters of this volume focus on the pathogenesis and etiology of each of the mentioned diseases, updated WHO reports wherever applicable, conventional drugs and their pharmacokinetics as well as new approaches to develop anti-infective agents. (benthambooks.com)
What are the current challenges in the management of tuberculosis in patients with co-occurring lung diseases? (medicalexaminationhelp.com)
Home - Hire Someone To Do Tuberculosis & Chest Medicine Exam - What are the current challenges in the management of tuberculosis in patients with co-occurring lung diseases? (medicalexaminationhelp.com)
As there is inflammation, the treatment modalities that they use to treat them don't permit adherence to normal conditions because of not at all possible hypersecretion or hypercellWhat are the current challenges in the management of tuberculosis in patients with co-occurring lung diseases? (medicalexaminationhelp.com)
The objective of this paper is to summarize and discuss these current needs and problems, including a strategy to tackle them, and an analysis of the existing management recommendations of TB in patients with co-occurring lung diseases. (medicalexaminationhelp.com)
The systematic approach to TB management includes comprehensive knowledge, skills, and a consistent approach to the management of respiratory diseases. (medicalexaminationhelp.com)

The following is a list of common therapies and theories which patients seeking an alternative approach may encounter. (patient.info)

Because tuberculosis, even after it has been treated adequately, remains a pertinent and lifelong part of a person's medical history, previous as well as current disease is included in the classification. (cdc.gov)

Her presentation will focus on current AFM epidemiology and case reporting. (cdc.gov)

From 1999 onwards my research has been focused primarily on osteoblast biology and approaches to tissue engineer and model bone biology, pathology and repair. (nottingham.ac.uk)
Dr. Ho did her PhD work in herpesvirus pathogenesis and postdoctoral research in CNS gene therapy with viral vectors at Stanford University. (stanford.edu)
Ricky's current research is focused on the use and development of 3D printing as a way of inducing precise function or behaviour. (nottingham.ac.uk)
A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications. (mdpi.com)
In this article recently published in the International Journal of Bioprinting, iBB researchers Duarte Almeida, Paola Sanjuan-Alberte, João C. Silva and Frederico Ferreira provided an overview of the current state of the art of magnetic hydrogels, exploring the production of the magnetic components and their introduction in the hydrogels, and emphasizing the current research made on the applications of these materials for tissue engineering strategies. (scoop.it)

This role of inositol catabolism was published recently, 2023, in Current Biology back-to-back with work from our collaborator at Michican State, Dr. Sarah Lebeis . (uu.nl)
Current investigation focuses on the role of root hairs in root microbiome assembly and activity. (uu.nl)
Here I studied the role and evolution of fungal effectors during plant pathogenesis under the supervision of Prof. Pierre de Wit and Dr. Bart Thomma (current chair Phytopathology Wageningen UR). (uu.nl)
I investigated the role and evolution of fungal effectors from the tomato pathogenic fungi Cladosporium fulvum and Verticillium dahliae . (uu.nl)
1 investigated the role of NETs in the pathogenesis of acute lung injury in mice. (silverchair.com)
He also showed that double-stranded (ds)RNA- and ZDNA binding proteins had a role in poxvirus pathogenesis. (cdc.gov)

The accepted paradigm is that fungal sensitization occurs as a result of recurrent, transient environmental exposures. (einsteinmed.edu)

Hence, the authors propose that NETs do not contribute functionally to the pathogenesis of lung injury in this animal model. (silverchair.com)

Fungal culture can be used to identify the infecting organism, but the fungi may take several weeks to grow. (cdc.gov)

In tomato, resistance towards race 1 isolates of V. dahliae is governed by Ve1 , and we undertook an innovative next-generation sequencing approach to identify the corresponding avirulence gene. (uu.nl)
To implement effective RNAi against A. flavus requires identification of suitable gene target/s that are critical for fungal growth and aflatoxin production. (usda.gov)
In the current study we evaluated the importance of a polyamine (nitrogenous compound) biosynthetic gene, spermidine synthase (Spds) that is required to produce the polyamine spermidine (Spd), which is critical for living cells to survive. (usda.gov)
The results presented here show that targeting A. flavus Spds gene through RNAi approach in future might be effective in reducing both fungal growth and aflatoxin contamination in maize. (usda.gov)
Current evidence has been limited to mainly cross-sectional studies using 16S rRNA gene sequencing, attempting to answer the question 'who is there? (bmj.com)

This review provides an overview of the basic principles of high-throughput microbiome sequencing techniques, current literature on sputum microbiome profiling in COPD, and a discussion of the associated limitations and future perspectives. (bmj.com)

A basic approach that focuses on the prevention of chronic pain and disease is required as a best strategy to prevent TB. (medicalexaminationhelp.com)
Stephen C. Guptill (U.S. Geological Survey, Reston, VA) reported that the U.S. Geological Survey is working with the Centers for Disease Control and Prevention (CDC) to learn the current geographic extent of WNV. (cdc.gov)

Together, these observations may have important implications in developing new approaches to the treatment of anthrax. (einsteinmed.edu)

Hybrid genome assembly approaches leverage benefits of both long, relatively error-prone reads from third-generation sequencing technologies and short, accurate. (swan.ac.uk)
Hybrid genome assembly approaches leverage benefits of both long, relatively error-prone reads from third-generation sequencing technologies and short, accurate reads from second-generation sequencing technologies, to produce more accurate and contiguous de novo genome assemblies in comparison to using either technology independently. (swan.ac.uk)

It is therefore the only current diagnostic tool that allows the establishment of a link between the potential causative agent and the specific changes in cell and tissue ( Work & Meteyer, 2014 ). (peerj.com)

My current interests are directed towards large-scale sequencing and phylogenomic studies investigating major public health threats, such as the causative agents of plague and cholera, Yersinia pestis and Vibrio cholerae , and the dominant cause of food-borne disease in North America, Escherichia coli O157:H7. (utsa.edu)
1. Fungal sensitization in childhood persistent asthma is associated with disease severity. (einsteinmed.edu)
With current studies and technologies, the disease caused by pathogenic microbes in the soil can be controlled. (usim.edu.my)
This article focuses on dental management of oral erythema, but, in cases of systemic disease, a more comprehensive medical approach to therapy is necessary. (medscape.com)

Interestingly, fungal sensitization is more common in children and has been linked to severe asthma resulting in death. (einsteinmed.edu)

The book integrates the conventional (or Western) medical approach to male infertility with traditional Chinese medicine. (benthamscience.com)

Despite significant improvements in our understanding of the pathogenesis of HCC over the past few decades, we still do not have a comprehensive understanding of the major molecular pathogenic processes involved in liver carcinogenesis. (biomedcentral.com)

Current EOS incidence is ∼0.8 cases per 1000 live births in United States. (mhmedical.com)

A strategy to identify effective approaches is, therefore, important. (medicalexaminationhelp.com)
As the glyoxylate cycle is an important pathway in the utilization of alternative carbon sources, we also highlight the key metabolic enzymes in the glyoxylate cycle and its necessity for the pathogenesis of C. glabrata . (biomedcentral.com)

Information about new antimicrobials (bioactive peptides and silk protein sericin) and the approaches taken by scientists and healthcare professionals for successful targeting of these molecules for human medicine. (benthambooks.com)

Personalized nutrition is based on the idea that individualizing nutritional advice will be more effective than more generic approaches. (hrb.ie)

Monocytes can also present fungal antigens to elicit adaptive immune responses. (frontiersin.org)
Droplet nuclei are so small (1 to 5 um) that air currents normally present in any indoor space can keep them airborne for long periods of time. (cdc.gov)

Broadly, the approaches of EMA are similar to those of FDA. (amr.solutions)

I work on various biochemical and biophysical approaches to investigate and control cell-cell, cell-scaffold interactions. (nottingham.ac.uk)

La réanimation agressive, la prise en charge nutritionnelle, l'excision chirur- gicale complète des plaies infectées, la fermeture rapide des plaies, les greffes et la mise au point d'une chimiothérapie locale et systémique efficace ont permis d'améliorer grandement le taux de morbidité et de mortalité chez les patients brûlés. (who.int)

Inactivation of Spds significantly reduced mycelial growth and sporulation in vitro and addition of exogenous Spd was required to restore fungal growth and sporulation. (usda.gov)

The pathogenesis of organ injury, including acute respiratory distress syndrome (ARDS), includes the liberation of endogenous molecular structures called "danger-associated molecular patterns" that are associated with inflammation and tissue injury. (silverchair.com)

Our recent studies with the Cu,Zn SOD ( SOD1 ) and MnSOD ( SOD2 ) knockout mutants of Cg indicated that these antioxidants are crucial for Cg pathogenesis ( 12 , 13 ). (cdc.gov)
In addition to fungal studies, my lab is interested in anthrax pathogenesis. (einsteinmed.edu)
For those 11th in the phagocytes, but without a angular video of antigen in them, each of the three studies of the approach indicates heated by a such modulation of the applied apoptosisof meanings. (plywoodskyscraper.com)

Current concepts suggest that a limited number of molecular alterations involving oncogene activation and tumor suppressor inhibition are responsible for initiation of cancer. (biomedcentral.com)
Current concepts and approaches on animal test alternatives. (cdc.gov)

The best way to approach your literature review is to break it down into steps. (literaturereview.wiki)
In this review, we discuss alternative carbon metabolism as a metabolic adaptation strategy for the pathogenesis of C. glabrata . (biomedcentral.com)

Anatomy11

Organisms8

Diseases12

Chemicals and Drugs12

Analytical, Diagnostic and Therapeutic Techniques and Equipment27

Psychiatry and Psychology1

Phenomena and Processes24

Disciplines and Occupations6

Technology, Industry, Agriculture1

Information Science8

Health Care9

Geographicals1

Infections22

Pathogens5

Opportunistic fungal pathogen2

Pathogen1

Species2

Virulence1

Diagnosis8

Infection10

Mechanisms3

Susceptibility2

Colonization1

Intracellular1

Invasive1

Candida1

Therapeutic3

Microbiology1

Clinical2

Organisms2

Diseases6

Therapies1

Tuberculosis1

Epidemiology1

Research5

Role6

Occurs1

Lung1

Fungi1

Gene5

Principles1

Prevention2

Observations1

Genome2

Establishment1

Disease4

Common1

Conventional1

Significant1

Incidence1

Important2

Protein1

Effective1

Present2

Similar1

Cell1

Patients1

Growth1

Tissue1

Studies3

Concepts2

Review2