• 16 Describe methods of additional analyses (e.g., sensitivity or subgroup analyses, meta-regression), if done, N/A indicating which were pre-specified. (cdc.gov)
  • Some subgroup analyses could not be performed due to heterogeneity in data. (ajmc.com)
  • 4 Heterogeneity 15 Overview 105 16 Identifying and Quantifying Heterogeneity 107 17 Prediction Intervals 127 18 Worked Examples (Part 2) 135 19 Subgroup Analyses 149 20 Meta-Regression 187 21 Notes on Subgroup Analyses and Meta-Regression 205 Pt. (who.int)
  • Study design, size, duration: Systematic review of studies published between 1980 and 2020, followed by aggregated meta-analysis and CMA to track the accumulation of evidence over the period of time. (elsevierpure.com)
  • Last week, the US Department of Agriculture, which oversees the guidelines, announced that, for the first time, the departments will seek public comments on the proposed priority topics and supporting scientific questions for the 2020 Dietary Guidelines. (westonaprice.org)
  • Of course in 2020 you can't avoid the topic of the COVID-19 pandemic. (medscape.com)
  • en & Kaya, 2020), but also income distribution (Bar- gain et al. (lu.se)
  • A propensity score analysis was used to match patients with and without dementia (up to 3:1) according to age, sex, comorbidities, year, and hospital of admission. (bvsalud.org)
  • Consistent significant associations were observed among most propensity score analyses. (qxmd.com)
  • 1 was the two most recent analyses (2015−2016 and 2017−2018) of the National Health and Nutrition Examination Survey. (sniglobal.org)
  • Several sensitivity analyses, for example, including (i) those using change of the sum of all HDRS-17 items as effect parameter, (ii) those excluding all subjects with adverse events (that is, also those on placebo) and (iii) those based on the intention-to-treat population, were all in line with the primary analyses. (madinamerica.com)
  • Methods for quantifying heterogeneity, model diagnostics, and for conducting sensitivity analyses will be covered as well. (wvbauer.com)
  • While three observational studies were included in this review, their estimates have a potential for bias and we did not perform a meta-analysis. (springeropen.com)
  • Among both observational studies and meta-analyses, there are frequent reports of significant dose-response associations suggestive of causation, and frequent reports of no threshold of consumption below which associations are absent. (bmj.com)
  • We conducted a systematic review and targeted meta-analyses to investigate the effectiveness of food safety education interventions for consumers. (biomedcentral.com)
  • The dataset and analysis supporting the conclusions of this article are available in the Synapse repository, unique DOI 10.7303/syn25750338.1 . (plos.org)
  • We have defined the update frequency as 4 months, based on an assessment of the pace of evidence production on this topic. (bmj.com)
  • We explored this hypothesis in a patient-level post hoc-analysis including all industry-sponsored, Food and Drug Administration-registered placebo-controlled trials of citalopram or paroxetine in adult major depression that used the Hamilton Depression Rating Scale (HDRS) and included a week 6 symptom assessment (n = 15). (madinamerica.com)
  • Confidence in the cumulative evidence will be assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. (bcu.ac.uk)
  • Methods and analysis We will consider trials of second-line treatments in patients with advanced NSCLC with wild-type or unknown epidermal growth factor receptor status. (bmj.com)
  • Methods Adopting the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we evaluated 349 citations and identified 24 eligible reviews with medium to high methodological quality to be reviewed narratively. (bmj.com)
  • Meta-analysis denotes a particular approach to research synthesis that makes use of quantitative methods for aggregating and comparing the results from related studies in a systematic manner and has become the method of choice for summarizing the constantly growing body of research in the social, health, and natural sciences. (wvbauer.com)
  • The focus of this course is on current methods and techniques for conducting a meta-analysis. (wvbauer.com)
  • We will then delve into methods for combining the observed outcomes (i.e., via equal- and random-effects models) and for examining whether the outcomes depend on the characteristics of the studies from which they were derived (i.e., via meta-regression and subgrouping). (wvbauer.com)
  • Finally, we will examine some specialized methods for meta-analyzing 2x2 table data (the Mantel-Haenszel method, Peto's method, and logistic mixed-effects models), for meta-analyzing the results of regression models, and then cover a mixed bag of other topics (e.g., cumulative meta-analysis, missing data, Bayesian models). (wvbauer.com)
  • Methods Individual level data from a contemporary cohort of 6 29 624 patients with diagnosed HF was obtained from digital healthcare systems in participating countries using a prespecified, common study plan, and summarised using a random effects meta-analysis. (bmj.com)
  • 8 Further Methods 35 Overview 323 36 Meta-Analysis Methods Based on Direction and p-Values 325 37 Further Methods for Dichotomous Data 331 38 Psychometric Meta-Analysis 341 Pt. (who.int)
  • Data analysis: Cochrane methods for systematic reviews, including meta-analysis, were followed. (cdc.gov)
  • Structural racism is the "the normalization and legitimization of an array of dynamics - historical, cultural, institutional, and interpersonal - that routinely advantage non-Latino Whites while producing cumulative and chronic adverse outcomes for people of color" ( 1 ). (frontiersin.org)
  • Cumulative Remnant Cholesterol Predicts Cardiovascular Outcomes in Elderly Patients with Atherosclerotic Cardiovascular Disease. (qxmd.com)
  • Long-term cumulative RC was independently associated with incident MACE in elderly participants with ASCVD, suggesting that achieving and maintaining optimal RC levels later in life may still improve cardiovascular outcomes. (qxmd.com)
  • A sample of 606 primary studies, published from 1990 to 2010 in Language Learning and Studies in Second Language Acquisition , was collected and coded for designs, statistical analyses, reporting practices, and outcomes (i.e., effect sizes). (cambridge.org)
  • Uncontrolled before-and-after study outcomes were very heterogeneous and we have little confidence that the meta-analysis results reflect the true effect. (biomedcentral.com)
  • Some variation in outcomes was explained in meta-regression models, including a dose effect for behaviour outcomes in RCTs. (biomedcentral.com)
  • The researchers used Medline, Embase, Evidence-Based Medicine Reviews, Cumulative Index to Nursing and Allied Health Literature, and Web of Science Core Collection to search for studies for the review. (ajmc.com)
  • A systematic search of the Cochrane Library, Cumulative Index of Nursing and Allied Health Literature (CINAHL), MEDLINE, Embase and Scopus was performed. (aerzteblatt.de)
  • We queried the Cumulative Index of Nursing and Allied Health Literature (CINAHL), PubMed, Excerpta Medica dataBASE (EMBASE), and Web of Science databases for peer-reviewed research articles published up to December 2019 that examined the implementation of blockchain technology in health care settings. (jmir.org)
  • Research strategies: Pubmed, Embase, Web of Science, OSHupdate, Cochrane Central and Cumulative Index to Nursing and Allied Health Literature (CINAHL) were searched. (cdc.gov)
  • Cubism can evoke in our minds the methodology of research synthesis conducted via systematic reviews and meta-analysis. (cdc.gov)
  • Learning how to conduct and apply systematic reviews and meta-analysis may be similar to learning how to use machinery. (cdc.gov)
  • This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. (jmir.org)
  • Statistical analyses and quality of individual participant data network meta-analyses were suboptimal: a cross-sectional study. (jameslindlibrary.org)
  • False-positive findings in Cochrane meta-analyses with and without application of trial sequential analysis: an empirical review. (jameslindlibrary.org)
  • Cochrane method for systematic review and meta-analysis of interventions to prevent occupational noise-induced hearing loss - abridged (Revisão sistemática e metanálise Cochrane de intervenções para prevenção de perda auditiva ocupacional induzida por ruído - abreviada). (cdc.gov)
  • On July 25, 2017, Fredrik Hieronymus et al published a meta-analysis in Molecular Psychiatry . (madinamerica.com)
  • Heterogeneity analysis revealed that an increasing index of insulin resistance was independently associated with improving the performance of adiponectin upon metabolic syndrome diagnosis (ratio of diagnostic odds ratio = 3.89, 95% CI: 1.13-13.9). (frontiersin.org)
  • Meta-regression was conducted where appropriate to identify possible sources of between-trial heterogeneity. (biomedcentral.com)
  • We will start out by discussing the meta-analytic process as a whole (consisting of seven steps: problem formulation, literature search, information gathering, quality evaluation, analysis, interpretation of findings, and presentation of results). (wvbauer.com)
  • Voter information campaigns and political accountability: Cumulative findings from a preregistered meta-analysis of coordinated trials. (ucsd.edu)
  • Trial sequential analysis (TSA) corresponds to group sequential analysis of a single trial and may be applied to meta-analysis to evaluate the evidence. (nih.gov)
  • All meta-analyses will be conducted within a Bayesian framework, providing a flexible modelling approach to account for uncertainty in model parameters and underlying structures within the data. (bcu.ac.uk)
  • A major problem that may distort the results of a meta-analysis is publication bias (i.e., when the studies included in a meta-analysis are not representative of all the research that has been conducted on a particular topic). (wvbauer.com)
  • 6 Other Issues 27 Overview 249 28 Vote Counting a New Name for an Old Problem 251 29 Power Analysis for Meta-Analysis 257 30 Publication Bias 277 Pt. (who.int)
  • Combining data from similar studies (meta-analysis) can help to provide more reliable estimates of treatment effects. (jameslindlibrary.org)
  • Systematic reviews are rarely used to contextualise new results-a systematic review and meta-analysis of meta-research studies. (jameslindlibrary.org)
  • Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. (bmj.com)
  • Cumulative dose, amplitudes and frequency of treatments as well as subject posture during treatment vary widely among studies. (galileo-training.com)
  • A three-level random effects hierarchical meta-analysis was performed to assess the relationship between NS (global, expressive, and experiential dimensions) and the six MATRICS neurocognitive domains.nnRESULTS: 21 studies were included in the review (n = 3619). (mcgill.ca)
  • Analysis of a subset of the studies revealed that MATRICS neurocognitive domains also had small significant correlations with the two NS dimensions, expressive and experiential. (mcgill.ca)
  • Do you have specific studies or facts you want to share on these topics? (westonaprice.org)
  • There is important new data on both of these topics, with numerous studies and meta-analyses showing that the current recommendations (which oppose both a low-carbohydrate diet and reasonable consumption of saturated fats) are not in the best interests of Americans in general. (westonaprice.org)
  • 9 State the process for selecting studies (i.e., screening, eligibility, included in systematic review, and, if applicable, 9 included in the meta-analysis). (cdc.gov)
  • We included reviews and all other types of "umbrella"-studies of meta-data quantitatively comparing the translational results of studies including at least two species with one being human. (biomedcentral.com)
  • There were 36 studies included in the systematic review and 35 in a meta-analysis, which included 19,966 participants overall. (ajmc.com)
  • However, few studies have characterized long-term cumulative RC exposure among elderly people. (qxmd.com)
  • 8 Because suicides and suicide attempts are rare events, the inability to document an important difference may be a function of the small number of patients in single studies and meta-analyses published to date. (bmj.com)
  • Six studies with a total of 337 500 patients (PC 10 045, CC 327 455) were included for meta-analysis. (aerzteblatt.de)
  • After analysis of the studies retrieved, 21 studies were selected. (bvsalud.org)
  • The study aimed to evaluate the association between cumulative exposure to RC and incident major adverse cardiovascular events (MACE) by analyzing a cohort of elderly patients with ASCVD. (qxmd.com)
  • The time-weighted average (TWA) RC was expressed as cumulative exposure to RC averaged by years. (qxmd.com)
  • Noh H, Charvat H, Freisling H, Ólafsdóttir GH, Ólafsdóttir EJ, Tryggvadóttir L, Arnold M, Soerjomataram I. Cumulative exposure to premenopausal obesity and risk of postmenopausal cancer: A population-based study in Icelandic women. (who.int)
  • Quantitative definitions comprise correlation/regression (r 2 ) and meta-analyses (percentage overlap of 95% confidence intervals). (biomedcentral.com)
  • A meta-regression could also not be performed due to the sample size, which meant that important confounders could not be accounted for. (ajmc.com)
  • 21 Present results of each meta-analysis done, including confidence intervals and measures of consistency. (cdc.gov)
  • In the multivariable model adjusted for traditional cardiovascular risk factors, low-density lipoprotein cholesterol level, and most recent RC level, the hazard ratios for MACE that compared the high and low tertiles of the RC variables were 1.30 (95% confidence interval [CI], 1.16-1.44) for cumulative RC and 1.36 (95% CI, 1.23-1.52) for TWA RC. (qxmd.com)
  • In research synthesis, clinical and public health professionals examine the scientific literature on a certain topic from multiple years and perspectives. (cdc.gov)
  • Meta-analysts display the literature in one publication in different figures, including forest plots, funnel plots, and chronological cumulative meta-analysis. (cdc.gov)
  • The literature related to this topic is controversial, heterogeneous, and unclear despite the prospect of a major clinical effect.The aim of this study was to identify and systematically review the literature to assess the effect of whole body vibration treatments on bone mineral density (BMD) in postmenopausal women with a specific focus on the experimental factors that influence the stimulus. (galileo-training.com)
  • For example, one meta-analysis of the economic literature shows that a 10-percentage point increase in the share of trusting people within a country should raise annual per capita real GDP growth by about 0.5 percentage point. (deloitte.com)
  • This study aimed to assess the global prevalence of chronic pain in women diagnosed with HIV and also to identify any gaps in literature on the topic. (ajmc.com)
  • 357 41 Reporting he Results of a Meta-Analysis 365 42 Cumulative Meta-Analysis 371 43 Criticisms of Meta-Analysis 377 Pt. (who.int)
  • This proof-of-concept study in second-line treatments of advanced NSCLC will allow one for assessing the feasibility of live cumulative NMA and opening the path for this new form of synthesis. (bmj.com)
  • Systematic reviews on the topic have been published, but there are not many umbrella reviews that provide a more comprehensive and up-to-date synthesis of the data. (bmj.com)
  • In three significant meta-analyses the cumulative z-curves crossed both boundaries, establishing firm evidence of an intervention effect. (nih.gov)
  • TSAs may establish when firm evidence is reached in meta-analysis. (nih.gov)
  • The cumulative evidence shows that low-carb diets are safe and effective for combating obesity , highly promising for the treatment of Type 2 diabetes , and for improving most cardiac risk factors. (westonaprice.org)
  • Therefore, the reliability of the cumulative evidence from current papers on this topic is insufficient. (biomedcentral.com)
  • In this umbrella review, we synthesise global evidence on the impact of COVID-19 on the mental health of CYP from existing systematic reviews with and/or without meta-analysis. (bmj.com)
  • Meta-analysis was conducted on data subgroups stratified by key study design-intervention-population-outcome categories and subgroups were assessed for their quality of evidence. (biomedcentral.com)
  • Perversely, current guidelines, including those issued by ACOG , the DGAC , EFSA , and the NHS , speak of "safe" levels, despite such claims being overwhelmingly inconsistent with the cumulative scientific evidence. (bmj.com)
  • The potential impact of these topics on federal food and nutrition policies and programs is very significant, particularly for WIC, school lunches and similar programs. (westonaprice.org)
  • No fewer than 14 meta-analyses published in the past two decades unanimously report significant caffeine-related increased risk of harm. (bmj.com)
  • [ 3 ] A meta-analysis demonstrated a significant increase in the relative risk of implant failure in patients who smoked more than 20 cigarettes per day compared with nonsmokers. (medscape.com)
  • The subgroup analysis found a pooled prevalence estimate of 27.8% (95% CI, 19.7%-37.7%) for peripheral neuropathy subgroup. (ajmc.com)
  • Global prevalence of chronic pain in women with HIV: a systematic review and meta-analysis. (ajmc.com)
  • The authors seem to assume that publication analysis of the prevalence of neurotoxic and hemotoxic frequency indicates prevalence within the country of snakebites globally ( 1 ). (who.int)
  • Systematic review and meta-analysis of global prevalence of neurotoxic and hemotoxic snakebite envenomation. (who.int)
  • se trata de un estudio de revisión integrativa de la literatura nacional, en los portales BVS y Portal de Periódicos Capes y en las bases de datos Web of Science, CINAHL y PsycINFO. (bvsalud.org)
  • The primary analyses, which compared completers on active treatment without early adverse events to completers on placebo (with or without adverse events) with respect to reduction in the HDRS depressed mood item showed larger symptom reduction in patients given active treatment, the effect sizes being 0.48 for citalopram and 0.33 for paroxetine. (madinamerica.com)
  • Further biomechanical analyses to predict the propagation of the vibration waves along the body and assess the stimulation levels are required. (galileo-training.com)
  • Systematic reviews are rarely used to inform study design - a systematic review and meta-analysis. (jameslindlibrary.org)
  • Defining Rapid Reviews: a systematic scoping review and thematic analysis of definitions and defining characteristics of rapid reviews. (jameslindlibrary.org)
  • Saving lives by modifying the process of science: Estimated historical mortality associated with the failure to conduct routine prospective cumulative systematic reviews. (jameslindlibrary.org)
  • This systematic review and meta-analysis was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines ( 13 ). (aerzteblatt.de)
  • 0000-0002-4205-6841 and Meta-Analyses extension for Scoping Reviews. (bvsalud.org)
  • Reviews and Meta-Analyses extension for Scoping Reviews. (bvsalud.org)
  • The purpose of this systematic review and meta-analysis is to evaluate the effect of carnosine or β-alanine supplementation on markers of glycaemic control and insulin resistance in humans and animals. (bcu.ac.uk)
  • 1 Introduction 1 How a Meta-Analysis Works 3 2 Why Perform a Meta-Analysis 9 Pt. (who.int)
  • 9 Meta-Analysis in Context 39 Overview 355 40 When Does it Make Sense to Perform a Meta-Analysis? (who.int)
  • We assessed the cumulative z-curves' crossing of P=0.05 and the boundaries. (nih.gov)
  • In one nonsignificant meta-analysis the cumulative z-curves never crossed P=0.05 or the boundaries. (nih.gov)
  • Whole Body Vibration Treatments in Postmenopausal Women Can Improve Bone Mineral Density: Results of a Stimulus Focussed Meta-Analysis. (galileo-training.com)
  • Multivariable analysis further adjusted for family history of cardiovascular disease and cancer, physical activity, overall dietary pattern (alternate healthy eating index 2010), total energy intake, smoking status, alcohol consumption, menopausal status (women only), and postmenopausal hormone use (women only). (bmj.com)
  • 7 - 9 An early meta-analysis showed that SSRIs potentially decreased suicidal ideation as measured by a single question on the Hamilton depression score. (bmj.com)
  • This proof-of-concept study will be the first live cumulative network meta-analysis (NMA) evaluating second-line treatments in advanced non-small-cell lung cancer (NSCLC) with wild-type or unknown status for epidermal growth factor receptor. (bmj.com)
  • Students gain a deeper understanding of math concepts by narrowing their focus to fewer topics at each grade level. (harry-friseur.de)
  • While early cholecystectomy (surgical removal of the gallbladder independent of the means of access) has been unequivocally established as the gold standard for the management of young and fit for surgery patients with AC ( 1 3 ), the optimal management of critically ill and elderly patients with acute cholecystitis remains a topic of discussion. (aerzteblatt.de)
  • In food substitution analyses, consumption of nuts, legumes, or whole grains instead of dairy foods was associated with a lower mortality, whereas consumption of red and processed meat instead of dairy foods was associated with higher mortality. (bmj.com)
  • When analysis was restricted to trials that had explicit data for infants and explicit data for pediatric patients under 5 years old excluding infants, the estimates of pooled ORs were 0.53 (95% CI: 0.20-1.40) and 0.68 (95% CI: 0.38-1.22), respectively. (springeropen.com)
  • Only articles comparing CC and PC for the definitive management of critically ill patients with AC were included for meta-analysis. (aerzteblatt.de)
  • First of all, although all aspects of the entire meta-analytic process will be discussed, emphasis will be placed on the analysis and interpretation step. (wvbauer.com)
  • Further Mendelian randomization analysis identified that the amplified risk could be attributed to increased susceptibility (up to 7%) to insulin resistance compared with women. (frontiersin.org)
  • Enter search terms to find related medical topics, multimedia and more. (msdmanuals.com)
  • Six randomly selected neonatal meta-analyses with at least five trials reporting a binary outcome were examined. (nih.gov)
  • Data mining is a related (parallel) field of study, focusing on exploratory data analysis through unsupervised learning. (wikipedia.org)
  • Scheduled maintenance: October 22, 2023 from 04:00 AM to 05:00 AM. Big Ideas Math Algebra 2 Answers Chapter 11 Data Analysis and Statistics assists students to learn strong fundamentals of concepts jotted down in this chapter. (harry-friseur.de)
  • To facilitate new knowledge development about temporal perspectives on the topic of sustainable employability from an organizational perspective, in this Special Issue, we present new meaningful results of eight different empirical papers. (researchgate.net)
  • Recent analyses indicate that environmental factors associated with vocabulary development and emergent literacy skills are already present among children as early as 15 months of age. (aft.org)