Loading...
  • lexical deci
  • In a previous experiment, Stremme, Troland, and Johansson (2014) found that beginner learners of Norwegian also experience an effect of meaning related words in a primed lexical decision task. (uib.no)
  • German and Spanish native speakers living in Norway were tested in a cross-linguistic primed lexical decision task. (uib.no)
  • Experiment 1 was a one-directional lexical decision task, where all primes were English words and their respective targets were Norwegian or non-words (L2-L1). (uib.no)
  • vivo
  • Adoptive transfer of transgenic OT-I T cells revealed highly efficient cross-presentation of the OVA/ISCOM vaccine in vivo, whereas cross-presentation of soluble OVA was poor even at a 100-fold higher concentration. (jimmunol.org)
  • To determine the contribution of DCs and MΦs to cross-priming of PLGA MS in vivo, DCs were depleted in transgenic CD11c-DTR mice, and MΦs were depleted by clodronate liposomes in wild-type mice before immunizing mice with OVA-encapsulated MS. Our results show that the depletion of DCs or MΦs alone only led to minor differences in the OVA-specific immune responses. (jimmunol.org)
  • The results presented in this work strongly suggest that in vivo cross-priming of PLGA MS-encapsulated Ag is performed by CD8 − DCs and MΦs. (jimmunol.org)
  • pathway
  • In contrast to "direct-presentation" of protein fragments synthesized within the cell, MHC class I presentation of exogenous Ag is based on a second pathway that was first described by Bevan in 1976 ( 6 ) and is referred to as cross-presentation ( 7 , 8 ). (jimmunol.org)
  • exogenous
  • In contrast, CD8 + T cell activation often occurs through interaction with specialized antigen-presenting cells displaying peptides acquired from an exogenous cellular source, a process termed cross-priming. (sciencemag.org)
  • Both in their functional XCR1 expression and their effective processing and presentation of exogenous antigen in the context of major histocompatibility complex class I, human CD141 + DCs correspond to mouse CD8 + DCs, a subset known for superior antigen cross-presentation in vivo. (rupress.org)
  • Others and we have demonstrated the selective ability of Batf3-dependent DCs but not Batf3-independent DCs to take up apoptotic cells (i.e., self), migrate to the draining lymph nodes (LNs) ( Supplemental Fig. 1A ), and there present exogenous cell-associated Ag peptides on MHC class I (i.e., cross-presentation) ( 4 , 7 - 10 ), which can then be recognized by cognate CD8 + T cells. (jimmunol.org)
  • Norwegian
  • The study tested the effect of Norwegian prime words on English L2 speakers living in Norway, but originating from different countries. (uib.no)
  • The test was designed to measure the priming effect of Norwegian prime words on L1 target words. (uib.no)
  • The hypotheses of the study are (1) Norwegian words will have a priming effect on L1 meaning related target words for beginner learners of Norwegian and (2) German L1 speakers will experience a stronger priming effect from Norwegian prime words than Spanish L1 speakers, as German is more closely related to Norwegian than Spanish is. (uib.no)
  • The form and meaning influences on cross-linguistic English and Norwegian stimuli were tested across four categories: cognates (+ meaning, + form), translations (+ meaning, - form), lookalikes (- meaning, + form) and unrelated (- meaning, - form). (uib.no)
  • Experiment 2 investigated the same stimuli in the opposite language direction, such that all primes were Norwegian and their respective targets were English or non-words (L1-L2). (uib.no)
  • Experiment 4 was a mixed language experiment, where half of the targets in each category was English primed by Norwegian and the other half were Norwegian primed by English (L1-L2 and L2-L1). (uib.no)
  • These experiments were analyzed together in order to account for priming effect for each word pair in both language direction (English-Norwegian and Norwegian-English). (uib.no)
  • experiments
  • The accumulated results from all experiments suggest that, at least when the prime is visible for 100ms, the meaning bearing units for the prime words are activated aiding the process of word recognition in any of the language directions across these series of experiments. (uib.no)
  • viral
  • In these studies we have used this same HEK-NP model to study the effects of LCMV-NP cross priming on the LCMV immunodominance hierarchy following viral challenge. (queensu.ca)
  • proteins
  • After phagocytosis, PLGA MS release encapsulated proteins over a long period of time ( 9 , 10 ), which enter the cross-presentation machinery. (jimmunol.org)
  • effects
  • The vocabulary test scores did not correlate with the priming effects, indicating a difference between implicit and explicit language knowledge, but for the German L1 speakers, a positive correlation between the reaction times and the vocabulary test scores was observed. (uib.no)
  • The counterbalanced baseline accounted for the lexical reaction times, such that when the mean lexical reaction time was accounted for, the priming effects are clearer. (uib.no)
  • responses
  • The related effect of cross-tolerance can also effectively eliminate responses to selected self components. (rupress.org)
  • ability
  • The enhanced cross-priming ability of TIDCs after RT was dependent on autocrine production of type I IFNs. (aacrjournals.org)
  • The initial priming of CTLs requires MHC class I presentation by professional APCs that have the unique ability to provide costimulation via CD80 and CD86 after maturation ( 5 ). (jimmunol.org)
  • reaction
  • In a series of open priming lexical decision tasks, the influences of meaning form and lexical reaction time were investigated. (uib.no)
  • vaccine
  • Dengue vaccine development is complicated by the possibility of vaccine-enhanced severe dengue disease due to antibody-dependent enhancement by pre-existing cross-reactivity, as well as homotypic antibodies. (springer.com)
  • role
  • We also highlight a regulatory role for cross priming in immunodominance by showing that a single dose of HEK-NP can completely shift the immunodominance hierarchy of a typical LCMV infection. (queensu.ca)
  • effective
  • Moreover, we would argue that the cognitive nature of this event suggests that the CD4 + T cell actively modifies the APC, converting it into an effective stimulator for the successful priming of the CTL precursor. (rupress.org)