Coxiella. Medical search. Frequent questions

Coxiella is a taxonomic homonym: Coxiella (bacterium), genus of bacteria in the family Coxiellaceae Coxiella burnetii, the causative agent of Q fever Coxiella (gastropod), genus of snails from saline lakes in the family Pomatiopsidae This disambiguation page lists articles about distinct genera with the same name. (wikipedia.org)
Five spawns of Rhipicephalus sanguineus ticks in- Bacteriageneticallyrelatedto Coxiella burnetii havebeen fected with Candidatus C. massiliensis were used for an- found in ticks. (cdc.gov)
Coxiella burnetii ( 1 ). (cdc.gov)
and Coxiella burnetii by quanti- tients were infected with Coxiella -like bacteria only: 11 tative PCR (qPCR) ( 2 , 7 ). (cdc.gov)
Infection with Coxiella burnetii , the causative agent of Q fever, can result in life-threatening persistent infection. (biorxiv.org)
We previously demonstrated long-lived immunoreactivity in individuals with past symptomatic and asymptomatic Coxiella infection (convalescents) to promiscuous HLA-class II C. burnetii epitopes, providing the basis for a novel T-cell-targeted subunit vaccine. (biorxiv.org)
We studied the role of European rabbits ( Oryctolagus cuniculus ) as a reservoir for Coxiella burnetii in the Iberian region. (vetscite.org)
Coxiella burnetii , which is the cause of Q fever, is a zoonotic pathogen that infects multiple hosts. (vetscite.org)
Coxiella burnetii, the agent of Q fever, enters human monocytes through alpha(v)beta(3) integrin and survives inside host cells. (nih.gov)
Coxiella burnetii is an underreported zoonotic pathogen in many rural regions globally. (ajtmh.org)
Borrelia burgdorferi sensu lato, Coxiella burnetii, and Rickettsia spp. (medscimonit.com)
Coxiella burnetii , and Rickettsia spp. (medscimonit.com)
Description SERION ELISA classic Coxiella burnetii Phase 1 IgG/IgA resp. (qedbio.com)
Background SERION ELISA classic Coxiella burnetii tests are recommended for the detection of human antibodies in serum or plasma directed against Coxiella burnetii in Phase 1 or Phase 2. (qedbio.com)
SERION ELISA classic Coxiella burnetii IgM is recommended for the detection of acute Q-fever, while SERION ELISA classic Coxiella burnetii (Phase 2) IgG supports the differential diagnosis of infections of the respiratory tract, especially atypical pneumonia. (qedbio.com)
SERION ELISA classic Coxiella burnetii (Phase I) tests are recommended for the diagnosis of chronic Q-fever. (qedbio.com)
All SERION ELISA classic Coxiella burnetii are used for the serological therapy follow-up in acute and chronic diseases. (qedbio.com)
Coxiella burnetii is the causative agent of the zoonotic disease Q fever, and ruminants being considered as the main source for human infection. (ac.ir)
Coxiella burnetii in non-Hodgkin lymphoma tissue samples : Innocent until proven otherwise? (uu.nl)
Purpose: Coxiella burnetii has been suggested as a potential cause of B-cell non-Hodgkin lymphoma (B-NHL), as C. burnetii was detected in B-NHL tissues. (uu.nl)
Coxiella burnetii and Leishmania Mexicana Residing Within Similar Para" by Jess A. Millar, Raquel Valdés et al. (pdx.edu)
Coxiella burnetii is a bacterium that thrives in an acidic parasitophorous vacuole (PV) derived from lysosomes . (pdx.edu)
Q fever is a zoonotic disease caused by Coxiella burnetii . (vircell.com)
Title : Epidemic Genotype of Coxiella burnetii among Goats, Sheep, and Humans in the Netherlands Personal Author(s) : Tilburg, Jeroen J.H.C.;Roest, Hendrik-Jan I.J.;Buffet, Sylvain;Nabuurs-Franssen, Marrigje H.;Horrevorts, Alphons M.;Raoult, Didier;Klaassen, Corné H.W. (cdc.gov)
Coxiella burnetii, the causative agent of Q fever, is a zoonotic disease with potentially life-threatening complications in humans. (montana.edu)
The CoxBur dtec-qPCR comprises a series of species-specific targeted reagents designed for Coxiella burnetii detection by using qPCR. (geneticpcr.com)
Q fever is a zoonosis caused by Coxiella burnetii . (kitpcr.com)
Infection with Coxiella burnetii can be acute or chronic, and exhibits a wide spectrum of clinical manifestations. (kitpcr.com)
Q fever is a zoonotic disease with acute and chronic stages caused by the rickettsia-like organism Coxiella burnetii. (cdc.gov)
Disappearance of FDG uptake on PET scan after antimicrobial therapy could help for the diagnosis of Coxiella burnetii spondylodiscitis. (uniba.it)
Blood and CT-guided discovertebral cultures remained sterile (including for mycobacteria) and 16s PCR and in-house specific Coxiella burnetii PCR were negative. (uniba.it)
False detection of Coxiella burnetii-what is the risk? (nau.edu)
The aim of this study was to undertake a cross-sectional seroprevalence survey of Coxiella burnetii, the causative agent of Q fever, in beef cattle in Queensland. (qld.gov.au)
Goats are known reservoirs of Coxiella burnetii, the etiologic agent of Q fever. (biomedcentral.com)
Coxiella burnetii , an obligate intracellular pathogen of both humans and animals is the causative agent of Q-fever [ 1 ]. (biomedcentral.com)
Coxiella burnetii, an obligate intracellular bacterium, causes potentially fatal endocarditis several years after intial infection suggesting the bacterium's ability to persist long-term in the host. (pcom.edu)
Khademi P, Ownagh A, Mardani K, Khalili M. PCR-RFLP of Coxiella burnetii Plasmids Isolated from Raw Milk Samples in Iran. (ijmm.ir)
Several methods have been employed to identify Coxiella burnetii isolates based on the specific Coxiella burnetii QpH1 plasmid to distinguish the acute form from the chronic form of Q fever disease in humans and animals owing to the presence of unique gene sequences in this plasmid. (ijmm.ir)
A total of 86 isolates of Coxiella burnetii QpH1 plasmid, which were confirmed by the Nested-PCR method in 2018, were used to determine the RFLP panel of the QpH1 plasmid. (ijmm.ir)
The results of the nucleic acid sequencing of all 4 samples indicated that they had a Coxiella burnetii type (Nine Mile RSA493 strain). (ijmm.ir)
RFLP patterns exhibited no difference on the Coxiella burnetii QpH1 plasmid isolated from cow and buffalo milk. (ijmm.ir)
Hence, all isolates were genetically identical, and the infection in animals could originate from one Coxiella burnetii strain (Nine Mile RSA493 strain). (ijmm.ir)
Genotyping of Coxiella burnetii in sheep and goat abortion samples. (ijmm.ir)
2. Sobotta K, Hillarius K, Jiménez PH, Kerner K, Heydel C, Menge C. Interaction of Coxiella burnetii Strains of Different Sources and Genotypes with Bovine and Human Monocyte-Derived Macrophages. (ijmm.ir)
3. Hendrix LR, Samuel JE, Mallavia LP. Differentiation of Coxiella burnetii isolates by analysis of restriction-endonuclease-digested DNA separated by SDS-PAGE. (ijmm.ir)
4. Heinzen R, Stiegler G, Whiting L, Schmitt S, Mallavia L, Frazier M. Use of Pulsed Field Gel Electrophoresis to Differentiate Coxiella burnetii Strains a. (ijmm.ir)
5. Willems H, Ritter M, Jäger C, Thiele D. Plasmid-homologous sequences in the chromosome of plasmidless Coxiella burnetii Scurry Q217. (ijmm.ir)
6. Savinelli EA, Mallavia LP. Comparison of Coxiella burnetii plasmids to homologous chromosomal sequences present in a plasmidless endocarditis-causing isolate. (ijmm.ir)
7. Jäger C, Lautenschläger S, Willems H, Baljer G. Coxiella burnetii plasmid types QpDG and QpH1 are closely related and likely identical. (ijmm.ir)
Molecular characterization of Coxiella burnetii isolates by infrequent restriction site-PCR and MLVA typing. (ijmm.ir)
Establishment of a genotyping scheme for Coxiella burnetii. (ijmm.ir)
Infection with Coxiella burnetii in cows usually runs without typical symptoms. (academicjournals.org)
Serological evidence of coxiella burnetii and SARSCoV-2 co-infection: a case report. (actamedicaportuguesa.com)
So tell me David, what is Coxiella burnetii ? (cdc.gov)
Dr. David Swerdlow] Coxiella burnetii is an intracellular bacterium that causes Q fever. (cdc.gov)
Infection with Coxiella burnetii can be asymptomatic, acute, or chronic. (cdc.gov)
Coxiella burnetii is a category B bioterrorism agent because it is highly infectious, rather resistant to heat and drying, and can become airborne and inhaled by humans. (cdc.gov)
Dr. David Swerdlow] If there were an intentional spread of Coxiella burnetii , we didn't know who should be given preventative treatment, called post-exposure prophylaxis or PEP, to prevent illness. (cdc.gov)
Pregnant women are also at high risk following exposure to Coxiella burnetii . (cdc.gov)
It is crucial to know who should be treated and how, following an intentional release with possible BT agents, including Coxiella burnetii . (cdc.gov)
Q fever (see the image below) is a zoonosis caused by Coxiella burnetii, an obligate gram-negative intracellular bacterium. (medscape.com)
Coxiella burnetii study was to describe the clinical, microt and Brucella spp. (who.int)
phylogenomics of rooting the emerging pathogen, Coxiella burnetii. (bvsalud.org)

Coxiella -like bacteria have been associated with infection cal signs (fever, skin eschar, local lymph node enlargement) in birds ( 4 , 5 ). (cdc.gov)

Infection of THP-1 (human monocyte/macrophage) cells with Coxiella and Leishmania elicited disparate host responses. (pdx.edu)
Inhalation of low doses of Coxiella bacteria can result in infection of the host alveolar macrophage (AM). However, it is not known whether a subset of AMs within the heterogeneous population of macrophages in the infected lung is particularly susceptible to infection. (montana.edu)
ELISA further demonstrated Coxiella infection-dependent increase in PGE2 levels. (pcom.edu)
These studies indicate that during infection Coxiella T4SS actively manipulates cox-2 expression resulting in increased PGE2. (pcom.edu)

To explore pathogenicity to humans, we used and if a removed tick was positive for Coxiella -like bacte- molecular techniques targeting Coxiella- like bacteria to ria according to qPCR but no skin biopsy was sampled or retrospectively analyze skin biopsy samples and ticks col- when serologic results were positive. (cdc.gov)
Ticks were identified by matrix-assisted la- for the Coxiella -like bacteria associated with R. sanguin- ser desorption/ionization time-of-flight mass spectrom- eus , R. turanicus , and H. pusillus ticks to be Candidatus C. etry (Bruker Daltonics, Billerica, USA) ( 6 ). (cdc.gov)
On the basis of the aligned rrs (55%) Dermacentor marginatus , 7 (35%) R. sanguineus , gene sequences of Coxiella -like bacteria, we developed 1 (5%) R. bursa , and 1 (5%) Ixodes ricinus ticks. (cdc.gov)
Coxiella- a specific qPCR to detect the DNA of all Coxiella spe- like bacteria were found significantly less commonly in I. cies and degenerated primers aimed to amplify a 659-bps ricinus ticks (p = 0.002, relative risk = 0.5). (cdc.gov)

As Coxiella and Leishmania are highly divergent organisms that cause different diseases, we reasoned that their respective infections would likely elicit distinct host responses despite producing phenotypically similar parasite-containing vacuoles. (pdx.edu)
Additionally, we detected 257 micro RNAs (miRNAs) that were expressed in THP-1 cells, and identified miRNAs that were specifically expressed during Coxiella or Leishmania infections. (pdx.edu)
Collectively, this study identified host mRNAs and miRNAs that were influenced by Coxiella and/or Leishmania infections, and our data indicate that although their PVs are morphologically similar, Coxiella and Leishmania have evolved different strategies that perturb distinct host processes to create and thrive within their respective intracellular niches. (pdx.edu)

Our previous studies show that Coxiella manipulates host LD metabolism via the Type 4 Secretion System (T4SS), a major virulence factor which secretes bacterial effector proteins into the host cell cytoplasm to manipulate cellular processes. (pcom.edu)
Additionally, inhibiting LD breakdown almost completely inhibits bacterial growth suggesting that LD-derived lipids are critical for Coxiella intracellular survival. (pcom.edu)

We also evaluated sero- we used Epi Info 6.0 (https://wwwn.cdc.gov/epiinfo/html/ logic tests for Candidatus Coxiella massiliensis diagnosis. (cdc.gov)

While Coxiella initially infects alveolar macrophages, in endocarditis patients, it is also found in foamy macrophages containing neutral lipid storage organelles called lipid droplets (LDs). (pcom.edu)

Hence we hypothesize that Coxiella manipulates host cell LD metabolism to promote a PGE2-mediated immunosuppressive environment and survive long-term in the host. (pcom.edu)

Studies are ongoing to identify the direct correlation between LDs and PGE2 production in Coxiella-infected cells and their contribution to PGE2-mediated immunosuppression. (pcom.edu)
Future studies will determine the potential of blocking PGE2 production as a supplemental therapy for Coxiella endocarditis. (pcom.edu)

During 2011-2014, we identified patients in hospitals Coxiella spp. (cdc.gov)

Compared to uninfected cells, cox-2 was upregulated in Coxiella-infected macrophages but not T4SS mutant-infected cells. (pcom.edu)

Q fever is a zoonotic disease of worldwide significance caused by the obligate intracellular bacterium Coxiella burnetii. (nih.gov)
Q fever is a zoonotic disease caused by the bacterium Coxiella burnetii, a strictly intracellular pathogen that can cause acute and chronic infection. (qxmd.com)
The bacterium Coxiella burnetii (which causes Q fever) had the highest incidence because of a goat-related Q fever epidemic in the Netherlands from 2007 to 2019, peaking at 2,424 cases in 2009. (umn.edu)

Morpholgically, Coxiella resembles Rickettsia . (kenyon.edu)
When it was first disovered, Coxiella burnetii was thought to be a member of this species, and named Rickettsia burnetii . (kenyon.edu)
Coxiella burnetii and Rickettsia are two types of bacteria that can cause severe illness in humans. (epibiodev.blog)
Q fever is a zoonotic disease with acute and chronic stages caused by the rickettsia-like organism Coxiella burnetii. (cdc.gov)
Background: We conducted a study to identify Rickettsia, Coxiella, Leptospira, Bartonella, and Chikungunya virus infections among febrile patients presenting at hospitals in Bangladesh. (johnshopkins.edu)
This disease is caused by the rickettsia Coxiella burnetii . (petplace.com)

The aim of this survey was to assess the seroprevalence of antibodies against Coxiella burnetii ( C. burnetii ) in subjects at risk of exposure in Sicily, Southern Italy. (ijomeh.eu)

Five spawns of Rhipicephalus sanguineus ticks in- Bacteriageneticallyrelatedto Coxiella burnetii havebeen fected with Candidatus C. massiliensis were used for an- found in ticks. (cdc.gov)
Fard, S.R.N. and Khalili, M. (2011) PCR detection of Coxiella burnetii in ticks collected from sheep and goats in southeast Iran. (ankara.edu.tr)
2010) Coxiella burnetii in Humans and ticks in rural Senegal. (ankara.edu.tr)

Seroprevalence of Coxiella burnetii at animal and herd level was 22.3 (95% CI: 17.1-27.6) and 78.9 (95% CI: 60-97) percent, respectively. (civilica.com)

Coxiella Burnetii is also an obligate intracellular organism, because it can't make its own energy in the form of ATP. (osmosis.org)

2021. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540145/all/Coxiella_burnetii. (hopkinsguides.com)

Coxiella burnetii causes significant reproduction losses in livestock and the disease Q fever in humans. (edu.au)
In humans, the disease generally arises from inhalation of the aerosolized Coxiella organisms produced by infected livestock. (biomedcentral.com)
Coxiella burnetii is a category B bioterrorism agent because it is highly infectious, rather resistant to heat and drying, and can become airborne and inhaled by humans. (cdc.gov)

Q fever is caused by Coxiella burnetii - an intracellular pathogen. (utsa.edu)

4. [Coxiella burnetii endocarditis. (nih.gov)
10. Coxiella burnetii Endocarditis in a Patient with Systemic Lupus Erythematosus: A Case Report of a Diagnostic Challenge. (nih.gov)
15. A contemporary 16-year review of Coxiella burnetii infective endocarditis in a tertiary cardiac center in Queensland, Australia. (nih.gov)
16. [Prosthetic valve endocarditis due to Coxiella burnetii: six cases]. (nih.gov)
18. Coxiella burnetii endocarditis on bioprosthetic aortic valve, with peripheral arterial embolism. (nih.gov)

This is because animals such as cows and goats harbor Coxiella burnetii in large amounts, providing many opportunities for those working in agriculture to become infected. (kenyon.edu)
2004) Occurence, distribution, and role in abortion of Coxiella burnetii in sheep and goats in Sardinia, Italy. (ankara.edu.tr)

Dr. David Swerdlow] If there were an intentional spread of Coxiella burnetii , we didn't know who should be given preventative treatment, called post-exposure prophylaxis or PEP, to prevent illness. (cdc.gov)

Coxiella is a genus best known for the species Coxiella burnetii , the causative agent of Q fever. (kenyon.edu)
Coxiella burnetii , the most famous species of this genus, causes human Q fever (short for query fever). (kenyon.edu)

Molecular pathogenesis of Coxiella burnetii in a genomics era. (tamu.edu)
Molecular detection of Coxiella burnetii in raw meat samples collected from different abattoirs in districts Kasur and Lahore of Punjab, Pakistan. (bvsalud.org)

The agent of acute and chronic Q fever, Coxiella burnetii, occupies a unique niche among intracellular pathogens. (tamu.edu)
To date, a total of 191 clinical cases of acute Q fever (Figure 1) have been serologically confirmed at the VCL by a fourfold or greater rise in Q fever complement fixation phase II antibody titer or by a 1:20 or greater Coxiella burnetii-specific immunoglobulin M (IgM) titer using an indirect immunofluorescence test on a single serum specimen. (cdc.gov)

Akgün, E., Yılmaz, M., Pınarbaşı, E. (2006) Q-fever şüphesi olan hasta serum ve kan örneklerinde nested-PCR yöntemiyle Coxiella burnetii'nin saptanması. (ankara.edu.tr)

Coxiella are Gram-negative. (kenyon.edu)
Coxiella Burnetii , is a short, gram-negative rod that causes a disease called Q fever . (osmosis.org)
Now, Coxiella Burnetii is gram negative, meaning that its cell wall has a thin peptidoglycan layer so it cannot retain a stain called crystal violet stain. (osmosis.org)
Sheep are considered to be one of the main reservoirs for Coxiella burnetii , a gram-negative bacterium with high zoonotic potential. (q-gaps.de)

Dr. David Swerdlow] Coxiella burnetii is an intracellular bacterium that causes Q fever. (cdc.gov)

Occurrence and significance of Coxiella burnetii and Chlamydiales spp. (sztaki.hu)

Another plasmid, Coxiella burnetii plasmid QpDV , was sequenced in 1999. (kenyon.edu)
Nguyen, S.V. and Hirai, K. (1999) Differentiation of Coxiella burnetii isolates by sequence determination and PCR-restriction fragment length polymorphism analysis of isocitrate dehydrogenase gene. (ankara.edu.tr)

Blood samples were assayed for antibody to Coxiella burnetii using CHEKIT Q fever ELISA kit. (civilica.com)
1997) İnfertilite sorunu olan dişi sığırlarda ve insanlarda Coxiella burnetii antikorlarının ELISA testi ile belirlenmesi ve seroprevalansının saptanması. (ankara.edu.tr)

Regardless of the likelihood that C. burnetii may be used as a bioterrorism agent due to its status as a Q fever is caused by the intracellular bacterium Coxiella category B agent, public health agencies are obligated to burnetii and is endemic in nearly every country in the prepare for such a scenario. (cdc.gov)

2004) Detection of Coxiella burnetii by immunomagnetic separation-PCR in the milk of sheep in Turkey. (ankara.edu.tr)

Work on the genome structure of Coxiella is still in progress. (kenyon.edu)

High prevalence of antibody against Coxiella burnetii in the cattle population of the study area implies zoonotic and economic importance. (civilica.com)

Pregnant women are also at high risk following exposure to Coxiella burnetii . (cdc.gov)

Coxiella burnetii can cause a disease known as Q fever, which can cause flu-like symptoms and in severe cases can be fatal. (epibiodev.blog)

Our results demonstrate that these 7 Coxiella proteins gave a modest sensitivity and specificity for recognizing of Q fever patient sera, suggesting that they are potential serodiagnostic markers for Q fever. (biomedcentral.com)

The variables evaluated did not seem to have a significant effect on seropositivity to Coxiella with the exception of symptoms in the last 6 months preceding the survey. (ijomeh.eu)

High levels of Coxiella DNA were found in liver and spleen tissues (Figure 1 ) and the highest level was found in tissues obtained on day 7 pi. (biomedcentral.com)

Coxiella burnetii is a strict intracellular bacterium with potential as a bioterrorism agent. (nih.gov)
Coxiella burnetii is a category B bioterrorism agent. (cdc.gov)
Coxiella burnetii is the etiological agent of Q fever. (biomedcentral.com)

The Coxiella load in spleen tissues was significantly higher than that in liver or lung tissues and significantly decreased by day 14 pi (Figure 1 ). (biomedcentral.com)

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Rickettsia6

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