• A few years ago, we celebrated one of the prettiest discoveries in modern microbiology, achieving the growth of Coxiella burnetii outside its host cells in laboratory media (see Coxiella Escapes from Cell! ). (asmblog.org)
  • These autophagosomal features suggest that Coxiella vacuoles interact with the autophagic pathway. (asm.org)
  • The first description of what may have been Coxiella burnetii was published in 1925 by Hideyo Noguchi, but since his samples did not survive, it remains unclear as to whether it was the same organism. (wikipedia.org)
  • A negative result does not negate the presence of the organism or active disease, as false-negative results may occur due to inhibition of PCR, sequence variability underlying the primers and probes, or the presence of Coxiella burnetii in quantities less than the limit of detection of the assay. (mayomedicallaboratories.com)
  • Work on the genome structure of ''Coxiella ''is still in progress. (kenyon.edu)
  • Another plasmid, [http://www.ncbi.nlm.nih.gov/genomes/framik.cgi?db=Genome&gi=15234 ''Coxiella burnetii'' plasmid QpDV], was sequenced in 1999. (kenyon.edu)
  • Work has also been done on [http://www.ncbi.nlm.nih.gov/genomes/framik.cgi?db=Genome&gi=293 ''Coxiella burnetii'' RSA (kenyon.edu)
  • One of the more recent developments is the sequencing of [http://www.ncbi.nlm.nih.gov/genomes/framik.cgi?db=Genome&gi=17002 ''Coxiella burnetii'' RSA 493 plasmid pQpH completed in 2003. (kenyon.edu)
  • This is because animals such as cows and goats harbor ''Coxiella burnetii'' in large amounts, providing many opportunities for those working in agriculture to become infected. (kenyon.edu)
  • A Coxiella-type microbe occurs at 100% frequency in all Amblyomma americanum ticks thus far tested. (semanticscholar.org)
  • Laboratory-reared and field-collected Amblyomma americanum ticks were hosts of a Coxiella sp. (semanticscholar.org)
  • In comparison to wild-type C. burnetii , a strain that lacks tRNA Glu 2 exhibited reduced growth, indicating its importance to Coxiella 's physiology. (frontiersin.org)
  • Coxiella burnetii should also be considered in the differential diagnosis of febrile-like illnesses in Jordan, especially among farmers and veterinarians. (ajtmh.org)
  • Background and Aim: In the course of our Indian Council of Medical Research project on coxiellosis in Puducherry and Tamil Nadu, 5.64% goat, 1.85% sheep, 1.06% buffaloes, and 0.97% cattle were positive for Coxiella burnetii antibodies by enzyme linked immunosorbent assay kit (IDEXX, Liebefeld, Switzerland). (doaj.org)
  • Coxiella -containing large vacuoles were labeled with wild-type Rab7 (Rab7wt) and with GTPase-deficient mutant Rab7Q67L, whereas no colocalization was observed with the dominant-negative mutant Rab7T22N. (asm.org)