Signal TransductionMolecular Sequence DataCells, CulturedCell LineCalciumKineticsProtein BindingPhosphorylationAmino Acid SequenceMutationMice, Inbred C57BLMice, KnockoutBase SequenceTime FactorsDNA-Binding ProteinsTranscription, GeneticEnzyme ActivationRNA, MessengerTranscription FactorsApoptosisGene Expression RegulationTransfectionDose-Response Relationship, DrugModels, BiologicalCarrier ProteinsBinding SitesCell Line, TumorPromoter Regions, GeneticRecombinant ProteinsTumor Suppressor Protein p53Enzyme InhibitorsBlotting, WesternMembrane ProteinsHydrogen-Ion ConcentrationRecombinant Fusion ProteinsNuclear ProteinsCell MembraneHeLa CellsProtein-Serine-Threonine KinasesBiological TransportProtein TransportTumor Cells, CulturedBacterial ProteinsRats, Sprague-DawleyRNA, Small InterferingCell DivisionSodiumTrans-ActivatorsEscherichia coliCell NucleusCell SurvivalTranscriptional ActivationSaccharomyces cerevisiaeCell Cycle ProteinsCell DifferentiationMice, Inbred BALB CSaccharomyces cerevisiae ProteinsReverse Transcriptase Polymerase Chain ReactionTemperatureMice, TransgenicPlasmidsAdenosine TriphosphateMyeloid Differentiation Factor 88Membrane PotentialsCell CycleGene ExpressionUp-RegulationDNANeuronsFibroblastsCell ProliferationMacrophagesRabbitsRNA InterferenceMagnesiumMembrane GlycoproteinsCattleDNA PrimersCell MovementSequence Homology, Amino AcidDNA DamageProtein KinasesDown-RegulationCell AdhesionPhenotypeProtein Kinase CProto-Oncogene ProteinsCloning, MolecularFlow CytometrySubstrate SpecificityPotassiumImmunoblottingCricetinaeCalcium SignalingProteinsT-LymphocytesCytosolMicroscopy, FluorescenceRepressor ProteinsHEK293 Cells