Cortical bone bone. Medical search. Frequent questions

Denosumab is a well-known, effective agent for increasing BMD, both at trabecular and cortical sites, 11 , 12 and has been showed to prevent metacarpal bone loss in patients with RA, 13 and improve cortical porosity. (bmj.com)
14 An intriguing hypothesis is that the effects of denosumab in terms of prevention of bone erosions are mainly due to its positive effects on cortical BMD and porosity. (bmj.com)
Serum glycine was inversely associated with the bone strength parameter failure load in the distal tibia (Pâ€ =â€ 0.002), mainly as a consequence of an inverse association with cortical cross-sectional area and a direct association with cortical porosity. (lu.se)
Results indicated significant differences in all imaging parameters between pediatric controls and OI tissue, with OI bone showing drastically increased cortical porosity, canal diameter, and connectivity. (marquette.edu)
Preliminary mechanical testing revealed a possible link between cortical porosity and strength. (marquette.edu)

A notching and staining system was devised to reproducibly image denatured collagen on bovine cortical bone fracture surfaces. (uwaterloo.ca)

Bone marrow adipose tissue (MAT) contributes to increased circulating adiponectin, an insulin-sensitizing hormone, during caloric restriction (CR), but whether this occurs in other contexts remains unknown. (frontiersin.org)
In addition to WAT and BAT, adipocytes also exist in the bone marrow, and such marrow adipose tissue (MAT) has been estimated to account for over 10% of total adipose tissue mass in lean, healthy humans ( 3 ). (frontiersin.org)
[ 1 , 2 ] The remainder of the blood supply is through nutrient vessels that pierce the cortex and supply the marrow cavity and the inner two thirds of the cortical bone. (medscape.com)
As proof of high impact forces applied to cartilage and bone at the time of injury, traumatic bone marrow lesions and osteochondral fractures, located predominantly in the lateral tibiofemoral compartment, are commonly associated with an ACL injury. (lu.se)
West Nile Virus RNA was detected in samples from the spleen/lymph node, skin, and fat associated with the tibia bone, as well as 1 of 2 muscle specimens, 1 of 4 tendon specimens, and 1 of 2 bone marrow specimens. (cdc.gov)
Results of IHC staining of skin, fat, muscle, and bone marrow samples were negative for West Nile Virus antigens. (cdc.gov)
We identified West Nile Virus RNA in spleen/lymph node homogenate, skin, fat, muscle, tendon, and bone marrow samples obtained postmortem from a donor associated with transmission of West Nile Virus through solid organ transplantation. (cdc.gov)

The mean MTX concentrations in trabecular and cortical bone were 0.292 ± 0.164 and 0.286 ± 0.126 nmoles/gm, respectively. (urosario.edu.co)

Compared to a conventional pedicle screw, the use of a cortical threaded pedicle screw promises superior fatigue load in vertebrae with reduced bone quality. (springer.com)
Considering the stability of an implanted pedicle screw itself, it depends on the following three main factors: bone quality, implantation technique, and screw properties [ 14 ]. (springer.com)
The aim was to exhibit whether a pedicle screw with proximal doubling of the threads (cortical thread) is ahead of a standard conventional threaded pedicle screw in vertebral bodies with low bone quality. (springer.com)
Investigate the biomechanical properties of the hybrid fixation technique with bilateral pedicle screw (BPS) and bilateral modified cortical bone trajectory screw (BMCS) in L4-L5 transforaminal lumbar interbody fusion (TLIF). (biomedcentral.com)
The main reason for screw loosening is that pedicle screws are mainly fixed by cancelous bone, and it is often compromised in patients with osteoporosis. (biomedcentral.com)
Buyers can avail Bone Screws such as Cancellous Screws, Cannulated Screws, Cortex Screw, Locking Screw and Malleolar Screw from us. (sofiaorthocare.com)

Bone density (BMD) was determined by quantitative computed tomography. (springer.com)
QRM, Moehrendorf, Germany) to enable subsequent determination of the apparent volumetric bone mineral density (vBMD) in terms of mg calcium hydrogen carbonate per cm 3 . (springer.com)
On the other side, from the bone point of view, we previously observed that low bone mineral density (BMD) at the cortical site was significantly associated with the presence of bone erosions, 8 and recently Zhu and colleagues reported alterations in the density and microstructure of the cortical bone of patients with RA, providing new insight into the microstructural basis of bone involvement in RA. (bmj.com)
Context: In a recent study a pattern of 27 metabolites, including serum glycine, associated with bone mineral density (BMD). (lu.se)
Schmidutz F, Schopf C, Yan SG, Ahrend M, Ihle C, Sprecher C. Cortical bone thickness of the distal radius predicts the local bone mineral density. (boneandjoint.org.uk)
This study evaluated the capability of a cortical index (CI) at the distal radius to predict the local bone mineral density (BMD). (boneandjoint.org.uk)
Assessment of local bone mineral density (BMD) with standard radiographs (XRs) if quantitative measurements (dual-energy X-ray absorptiometry (DXA), high-resolution peripheral quantitative CT (HR-pQCT)) are not available. (boneandjoint.org.uk)
Bones In mice, irisin is released from skeletal muscle during exercise acts directly on bone by increasing cortical bone mineral density, bone perimeter and polar moment of inertia. (wikipedia.org)
Sclerosing bone disorder (SBD) is a heterogeneous group of monogenic diseases characterized by increased bone density. (nature.com)
They used quantitative CT scans and dual-energy X-ray absorptiometry (DXA) to measure bone size and bone mineral density. (nih.gov)
X-ray of bone abnormalities, syphilitic metaphysitis in an infant with diminished density in the ends of the shaft and destruction at the proximal end of the tibia (right). (cdc.gov)

Cortical bone refers to the harder, more compact bone that forms the outer bony surface of the diaphysis . (psychology-lexicon.com)
Diaphysis refers to the long cylindrical portion or shaft of long bones. (psychology-lexicon.com)
At the end of the 8-wk experimental period, bone histomorphometric analyses of the cancellous bone of the proximal tibial metaphysis and cortical bone of the tibial disphysis was performed, and the mechanical properties of the bone were evaluated at the femoral distal metaphysis (FDM) and femoral diaphysis (FD). (fujita-hu.ac.jp)
Mature long bones have 3 distinct zones: epiphysis, metaphysis, and diaphysis (see the image below). (medscape.com)
Like most sections of bone, it is strong, but it lacks the rigidity of the diaphysis. (medscape.com)
Clinical manifestations of early congenital syphilis might include rhinitis ("snuffles"), hepatosplenomegaly, skin rash with desquamation, chorioretinitis and pigmentary chorioretinopathy (salt and pepper type), glaucoma, cataracts, interstitial keratitis, optic neuritis, periostitis and cortical demineralization of metaphysis and diaphysis areas of long bones, anaemia and thrombocytopenia. (cdc.gov)

The classical three-point bending and impact tests were carried out for three rat bone groups: control (SHO), the humerus of animals under the conditions of established osteopenia (OVX), and bones of rats receiving nesfatin-1 after ovariectomy (NES). (mdpi.com)
The researchers focused on the humerus, the upper arm bone running from shoulder to elbow. (nih.gov)
The throwing arms of baseball players had more bone on the outer surface of the humerus (cortical bone), creating a bone with a bigger diameter. (nih.gov)

All bone meets these biological requirements as a composite of hydroxyapatite mineral, protein (mainly type-I collagen) and water. (uwaterloo.ca)
The bone mineral content reaches a maximum value during the 30s and then declines beginning in the 40s in women. (active-seti.info)

CONCLUSION: Signal can be detected from normal and abnormal cortical bone with UTE pulse sequences, and this can be used to measure its T(1) and T(2)* as well as observe contrast enhancement. (ox.ac.uk)
Sclerosis (abnormal hardening) of cortical bone, characterized by increased radiodensity. (mcw.edu)

Objective: To investigate associations for serum and urinary glycine levels with BMD, bone microstructure, and fracture risk in men. (lu.se)
Introduction: The three-dimensional (3D) microstructure of the cortical and trabecular bone of the proximal ulna has not yet been described by means of high-resolution 3D imaging. (edu.au)
The aim of this study is to describe the proximal ulna bone microstructure using micro-computed tomography (micro-CT) and relate it to gross morphology and function. (edu.au)
The cortical thickness of the trochlear notch and the trabecular bone microstructure were measured in the olecranon, bare area and coronoid. (edu.au)
Studying the proximal ulna bone microstructure helps understanding its possible everyday mechanical loading conditions and potential fractures. (edu.au)
Effects of sex and age on bone microstructure at the ultradistal radius: a population-based noninvasive in vivo assessment. (lievers.net)

Non-responders to the DMARDs in terms of progression of bone erosions could be indeed the consequences of a concomitant osteoporosis. (bmj.com)
Ultrasonic backscatter may be able to detect changes in bone caused by osteoporosis. (aip.org)
These results indicate that CCM is sensitive to naturally occurring variations in bone tissue and may be sensitive to changes in bone tissue caused by osteoporosis. (aip.org)
In a case of osteoporosis, bone cross-sectional area and signal level appeared reduced. (ox.ac.uk)
It thus can serve as an initial screening tool to estimate the local bone quality if quantitative BMD measurements are unavailable, and enhance decision-making in acute settings on fracture management or further osteoporosis screening. (boneandjoint.org.uk)
Division of Endocrinology and Metabolism, Center for Osteoporosis and Metabolic Bone Diseases, University of Arkansas for Medical Sciences, Little Rock, AR, USA. (bvsalud.org)
Osteoporosis is a chronic and progressive disease characterized by decreased bone mass and deterioration of the microscopic structure of bone causing it to be prone to fracture (1), and consequently the condition affects quality of life (2,3). (who.int)

Apatos nanocrystalline hydroxyapatite is available in cortical and mixed granules. (medicalbone.nl)

Bone Healing and Regeneration Potential in Rabbit Cortical Defects Using an Innovative Bioceramic Bone Graft Substitute. (tmu.edu.tw)

Bone is a highly versatile tissue. (uwaterloo.ca)
Eriksson AR , Albrektsson T . Temperature threshold levels for heat-induced bone tissue injury: a vital-microscopic study in the rabbit. (avma.org)
Temperature threshold levels for heat-induced bone tissue injury: a vital-microscopic study in the rabbit. (avma.org)
The natural microporous consistency of Apatos facilitates the formation of new bone tissue in bone defect area⁵, accelerating the process. (medicalbone.nl)
We wished to determine whether it was possible to use ultrashort TE (UTE) pulse sequences to detect signal from cortical bone in human subjects and use this signal to characterise this tissue. (ox.ac.uk)
We measure a stronger covariation signal between cortical bone and dentine volumes than with any other dental tissue. (smu.ac.za)
RIS prevented the decrease in the cancellous bone volume/total tissue volume (BV/TV) noted in ovariectomized rats in a dose-dependent manner, by suppressing increases in cancellous bone formation and resorption, without any apparent effect on the Ct Ar or maximum load of the FDM or FD. (fujita-hu.ac.jp)
The investigations on the response of bone tissue under different loading conditions are important from clinical and engineering points of view. (mdpi.com)
Under certain circumstances, however, this apparently inert lead will leave the bones and reenter the blood and soft tissue organs. (cdc.gov)
Bone is a living tissue that responds to physical activity by becoming heavier, bigger, and stronger. (nih.gov)
[ 1 ] All bones are encased in a soft tissue envelope known as the periosteum, which is vital for perfusion and nutrient supply to the outer third of the bone (see the image below). (medscape.com)
Dental positions which may cause a gingival recession in the incisors are modified, as well as muscles and soft tissue, in region, once the gingiva accompanies bone support order to prevent extractions (FRÄNKEL et al. (bvsalud.org)
Those subjects who sustained an osteochondral fracture with disrupted cortical bone in association with the soft tissue knee injury had increased joint inflammation. (lu.se)
Eight weeks after the donor's death, skin samples that had been treated in cryopreservative solution containing an antibiotic and unprocessed fat, muscle, tendon, and bone samples, all of which had been stored frozen at -70° Celsius at a tissue bank, were transferred to CDC. (cdc.gov)

ZGRAFT™ Mineralized Cortical Cancellous Allograft Particulate blend provides a safe alternative to an autograft with no need for a second surgical site. (bonegrafting.com)
Holtzclaw D. Extraction site preservation using new graft material that combines mineralized and demineralized allograft bone: a case series report with histology. (nobelbiocare.com)

Cortical and trabecular bone parameters of the distal tibia were measured at follow-up using high-resolution peripheral quantitative computed tomography. (lu.se)
The use of high resolution peripheral quantitative computed tomography (HR-pQCT) and in vivo micro-CT for studies of bone disease and treatment has become increasingly common, and with these methods comes large quantities of data requiring analysis. (lievers.net)
Accuracy of high-resolution peripheral quantitative computed tomography for measurement of bone quality. (lievers.net)

Consistently among the ulnae, the coronoid showed the highest cortical thickness (1.66 ± 0.59 mm, p = 0.04) and the olecranon the lowest (0.33 ± 0.06 mm, p = 0.04). (edu.au)
The bare area exhibited the highest bone volume fraction (BV/TV = 43.7 ± 22.4%), trabecular thickness (Tb.Th = 0.40 ± 0.09 mm) and lowest structure model index (SMI = - 0.28 ± 2.20, indicating plate-like structure), compared to the other regions (p = 0.04). (edu.au)
Cortical bone thickness (CBT) of the distal radius was measured on XR and CT scans, and two cortical indices mean average (CBTavg) and gauge (CBTg) were determined. (boneandjoint.org.uk)
The mean average cortical bone thickness (CBTavg) allows prediction of the local BMD. (boneandjoint.org.uk)
Compared to humeral bones in non-throwing arms, those in throwing arms had about 50% greater mass, size (total cross-sectional area), and thickness. (nih.gov)
Treatment of Class II malocclusion with in relation to the limit of movement, because functional orthopedic appliances works in the patients prone to vertical growth have a smaller anterior discrepancy of the jaws by guiding growth thickness of the buccal bone at the symphysis, towards a more favorable direction. (bvsalud.org)

Design, setting, and participants: Tibial (cortical) and patellar (trabecular) bone lead levels were measured by K x-ray fluorescence between 1991 and 1999 in a subset of participants in the Normative Aging Study (NAS), a Boston-based longitudinal study of aging in men. (cdc.gov)

The creos allografts portfolio offers you a wide range of particulate grafts, a 100% demineralized bone matrix (dbm) putty and a pericardium barrier membrane. (nobelbiocare.com)

When needed, Apatos grafts can be protected with OsteoBiol ® Evolution membrane or stabilized with Cortical Lamina . (medicalbone.nl)
To determine methotrexate (MTX) concentrations in the synovial membrane (SM) and cortical and trabecular bone of rheumatoid arthritis (RA) patients. (urosario.edu.co)

Bones vary widely in size, ranging from the tiny inner ear bones that are responsible for transmitting mechanical sound waves to the sensory organs to the large (nearly 2 ft long) femur bone that is strong enough to withstand 30 times one's body weight. (medscape.com)
Long bones are formed from a cartilage model precursor by endochondral ossification (see the image below) and can range in size from a phalanx to a femur. (medscape.com)

The interior of the bone cyst may contain complete or nearly complete thin bony septations within it. (medscape.com)
Most bones have a thick, well-organized outer shell (cortex) and a less dense mesh of bony struts in the center (trabecular bone) (see the image below). (medscape.com)
Most commonly associated with joint surfaces, it usually comprises a thin, compact bone shell with a large amount of bony struts (trabecular bone) for support of the cortical shell. (medscape.com)

Associations were evaluated using linear regression (bone parameters) or Cox regression (fractures). (lu.se)
Reduction in signal from short T(2) components was seen in acute fractures, and increase in signal in these components was seen with new bone formation after fracture malunion. (ox.ac.uk)

This fact, combined with the endochondral formation of cortical bone, means that rat femoral cortical bone contains highly mineralized cartilage islands in a central band of mid-femoral cross sections. (au.dk)
The calcified cartilage islands were distributed in a central zone of the bone, from the growth plates through the mid-femoral bone. (au.dk)

Takeuchi et al 1 demonstrate an additional inhibitory effect on the progression of bone erosions in rheumatoid arthritis (RA) with the addition to methotrexate of an anti-receptor activator of nuclear factor kappa-B ligand (RANKL) antibody, denosumab, confirming results already reported 8 years ago by Cohen and colleagues. (bmj.com)

abstract = "Cortical bone and dentine share similarities in their embryological origin, development, and genetic background. (smu.ac.za)
abstract = "The purpose of the present study was to compare the effects of risedronate (RIS) and alfacalcidol (ALF) on the cortical and cancellous bone mass and mechanical properties in ovariectomized rats in a head-to-head fashion. (fujita-hu.ac.jp)

Conclusions: Serum and urinary glycine are indirectly associated with FN-BMD and cortical bone strength, and directly associated with fracture risk in men. (lu.se)

Eriksson RA , Albrektsson T , Magnusson B . Assessment of bone viability after heat trauma. (avma.org)
Assessment of bone viability after heat trauma. (avma.org)

Endochondral ossification of long bones through cartilage precursor. (medscape.com)

To be physiologically useful as a biomaterial, bone must be stiff and resist deformation, but also be capable of dissipating large amounts of energy while resisting failure. (uwaterloo.ca)

Is the Subject Area "Bone resorption" applicable to this article? (plos.org)
Apatos Cortical is characterized by a very long resorption time, guaranteeing optimal preservation of the graft volume. (medicalbone.nl)
On the other hand, ALF increased the cancellous BV/TV, Ct Ar, and maximum load of the FDM or FD, by mildly decreasing cancellous bone formation and resorption, increasing periosteal and endocortical bone formation, and preventing an increase in endocortical bone resorption. (fujita-hu.ac.jp)

The distal radius is a major site of osteoporotic bone loss resulting in a high risk of fragility fracture. (boneandjoint.org.uk)
The cortical index (CBTavg) at the distal radius shows a close correlation to the local BMD. (boneandjoint.org.uk)

Cortical bones of four bovine left femurs were used and ring-shaped cortical bone specimens from the middle shaft were obtained. (elsevierpure.com)

Blend of cortical and cancellous bone produced from sections of the ilium. (nobelbiocare.com)

Cxcl12 Deletion in Mesenchymal Cells Increases Bone Turnover and Attenuates the Loss of Cortical Bone Caused by Estrogen Deficiency in Mice. (bvsalud.org)

The current study represents one of the first attempts to characterize the 3D structure and composition of cortical bone in OI at the micron-scale. (marquette.edu)
Thus they illustrate natural variation in chemical composition that could have been overlooked in such studies or could have appeared as an undue error where the overall composition of the bone was investigated. (ox.ac.uk)
Quantifying the variation in mid-shaft cortical bone at the millimeter/centimeter scale reduces the possibility of natural heterogeneity obscuring the average bone composition, or being mistaken for experimental signal, and results in an improvement in the sampling accuracy analogous to that obtained by switching from micrometer-size point spectra of bones to spectral images obtained across hundreds of micrometers. (ox.ac.uk)

Known calcification rates of bones in childhood and adulthood suggest that lead accumulation will occur predominately in trabecular bone during childhood, and in both cortical and trabecular bone in adulthood [Auf der Heide and Wittmets 1992 as cited in ATSDR 2010]. (cdc.gov)

As such they provide a unique opportunity to probe the behavior of bone collagen during fracture. (uwaterloo.ca)
This result supports the hypothesis, suggesting that the denaturation of collagen is a crucial element of how bone resists fracture during stable fracture extension. (uwaterloo.ca)

The performance of the proposed method to segment cortical and trabecular compartments was evaluated qualitatively from visualizations and quantitatively based on morphological measurements. (lievers.net)

Laib A, Rüegsegger P. Comparison of structure extraction methods for in vivo trabecular bone measurements. (lievers.net)
Among the first 795 NAS participants to have bone lead levels measured, we reviewed eye examination data (collected routinely every 3-5 years) for the period after the bone lead measurements were taken. (cdc.gov)

This study assesses the relative in vivo performance of three ultrasonic backscatter parameters: cortical-cancellous mean (CCM), cortical-cancellous slope (CCS), and cortical-cancellous intercept (CCI). (aip.org)

The experiments proved that the bone strength parameters measured under various mechanical loading conditions increased after the nesfatin-1 administration. (mdpi.com)

A porous structured bone with particle size range from 0.25 mm to 1 mm and available volume of 0.25 cc to 2.0 cc. (nobelbiocare.com)

CCM was determined by frequency averaging the spectral power difference in decibels between echoes from the outer cortical surface and backscatter from underlying cancellous bone. (aip.org)
Exercise during youth adds extra layers to the outer surface of a bone to essentially make the bone bigger," Warden says. (nih.gov)

The relationship between the ultrasonic wave velocity and the preferred orientation of HAp crystallites in bovine cortical bones was investigated. (elsevierpure.com)

We demonstrate that these islands have a significantly higher degree of mineralization than the surrounding bone, using quantitative backscattered electron imaging. (au.dk)

The epiphysis is the region at the polar ends of long bones. (medscape.com)

Adult compact bone (including ribs) is composed of osteons with central vascular canals ( Fig. 1b-h ) that contain blood vessels and nerves in the living organism and lacunae, or spaces for the adult osteocytes ( Fig. 1m ). (nature.com)

J Bone Miner Res;35(8): 1441-1451, 2020 08. (bvsalud.org)

The mean fatigue load at failure was 264.9 N (1682 cycles) for the standard screws and was increased significantly to 324.7 N (2285 cycles) by the use of cortical threaded screws ( p = 0.014). (springer.com)
Nanoindentation revealed significantly higher values of both reduced modulus and hardness in the islands compared to the surrounding bone, reflecting a higher degree of mineralization. (au.dk)
Exploration of genes that cause SBD has significantly improved our understanding of the mechanisms that regulate bone formation. (nature.com)
Conclusion: The use of one conventional dental implant is preferable although it has significantly increased the bone stress magnitude for about 1.5-fold. (researchgate.net)

Skeletal manifestations include a selective cortical bone loss. (medscape.com)
Bone loss during aging occurred mostly on the inside of bones rather than the outside. (nih.gov)
Because of this pattern of bone loss, about half the bone size benefits of physical activity during youth and one-third of the bone strength benefits were maintained lifelong. (nih.gov)
Players who continued throwing during aging experienced less bone loss on the inside of the bone and maintained even more of the strength benefits. (nih.gov)
As bone loss during aging predominantly occurs on the inside rather than outside of a bone, the bigger bone generated by physical activity when young has a means of sticking around long-term to keep the skeleton stronger. (nih.gov)
With the onset of menopause, bone loss in women increases considerably: in the first 5-10 years the loss is 25-30% of trabecular bone and 10-15% of cortical bone. (who.int)

The main effects of parathyroid hormone are to increase the concentration of plasma calcium by increasing the release of calcium and phosphate from bone matrix, increasing calcium reabsorption by the kidney, and increasing renal production of 1,25-dihydroxyvitamin D-3 (calcitriol), which increases intestinal absorption of calcium. (medscape.com)

Irisin regulates bone remodeling and bone metabolism in animal models and humans. (wikipedia.org)
The aims of this study are to examine age-, sex-, and ancestry-related variation in cortical bone and dentine volumes, and to preliminary assess the possible covariation between these tissues in modern humans and in five composite Neandertals. (smu.ac.za)
Some variation exists, because humans may have different numbers of certain bones (eg, vertebrae and ribs). (medscape.com)

Osteogenesis imperfecta (OI) is a genetic disorder leading to increased bone fragility. (marquette.edu)

Tearing away of the CORTICAL BONE fragment at the location of a strong ligament or tendon attachment. (bvsalud.org)
In younger patients it is most often caused by a sudden forceful pull on a tendon in the opposite direction of the bone movement. (bvsalud.org)

The prognosis is excellent in those unusual cases where patients require curettage and bone grafting. (medscape.com)
Background: Zygomatic dental implants are extensively used for the treatment of severely edentulous atrophic maxillae as an alternative to the previous protocol treatment by bone grafting. (researchgate.net)
treatment by bone grafting. (researchgate.net)

Inadequate anchoring of pedicle screws in vertebrae with poor bone quality is a major problem in spine surgery. (springer.com)
The only bones that lack a true cortex are the vertebrae, which are covered by a compact condensation of trabecular bone. (medscape.com)

Association with other bone lesions, such as aneurysmal bone cyst , is rare. (medscape.com)

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