• some metabolic studies have observed that diets with a high GI or GL lead to an increase in triglycerides and reduced high density lipoprotein cholesterol (HDL-C) [ 4 - 6 , 12 - 14 ] and cause systemic inflammation [ 15 , 16 ]. (hindawi.com)
  • There is a low but consistent negative correlation between VLDL and HDL cholesterol. (bmj.com)
  • TC), triglycerides (TG) and low-density lipoprotein cholesterol. (who.int)
  • The ratios of total cholesterol to high density lipoprotein (HDL) cholesterol, and triglycerides were the most sensitive variables. (cdc.gov)
  • Correlations of blood pressure with weight, pulse rate, serum glucose, cholesterol, uric acid, smoking and alcohol consumption rates were very close to those of other surveys. (cdc.gov)
  • Cholesterol is a significant contributor to heart disease, but certain types of cholesterol, in particular high-density lipoprotein (HDL) cholesterol, actually has a negative correlation with cardiovascular disease. (chemistryviews.org)
  • At the same time, daily intake of cocoa in the form of dark chocolate has been shown to reduce oxidation of the cholesterol associated with heart disease, low-density lipoprotein (LDL) cholesterol. (chemistryviews.org)
  • Although high-density lipoprotein-cholesterol (HDL-C) showed a flat pattern for all ages in both genders, its level in women was higher than in men. (thieme-connect.de)
  • The total and HDL-cholesterol levels in populations of St. Petersburg (Russia) and Leipzig (Germany). (thieme-connect.de)
  • Loci associated with increased risk for depression were also associated with increased risk of coronary artery disease and higher total cholesterol, low-density lipoprotein and c-reactive protein levels, while there was a mixed pattern of effect direction for the other risk factors. (plos.org)
  • The levels of serum total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) were inversely associated with BMD in both pre- and post-menopausal women. (who.int)
  • The levels of high-density lipoprotein cholesterol (HDL-C) were not associated with BMD values at any of the sites in the pre- and post-menopausal subjects. (who.int)
  • It has been shown that elevated select 15 000 people aged 3 to 69 years serum levels of low-density lipoprotein from district 13 in the east of Tehran for the (LDL) cholesterol, total cholesterol and study. (who.int)
  • Sample size poprotein (HDL) cholesterol and abnormal was determined using a confidence interval blood glucose levels are the dominant risk of 95%, power of the study was 80%, attri- factors for CVD [ 4,5 ]. (who.int)
  • CVD risk factors (total cholesterol, LDL, taking any lipid lowering agents, diuretics, HDL, triglycerides, blood glucose and beta-blockers, corticosteroids, androgens or systolic and diastolic blood pressure) fish liver oil remained in this study. (who.int)
  • Moreover, the elevation of serum let-7 g was significantly associated with a low level of high-density lipoprotein cholesterol (p = 0.022) and high blood pressure (p = 0.023). (biomedcentral.com)
  • Serum triglyceride, total cholesterol and low and high density lipoprotein cholesterol levels (LDL-c and HDL-c) were determined by standard enzymatic procedures. (researchbib.com)
  • The correlation of the lipid profile was higher with body fat compared to the Body Mass Index(BMI): LDL-C r = 0.32 vs 0.26, HDL-C r = -0.46 vs -0.43, total cholesterol r = 0.15 vs r = 0.08. (researchbib.com)
  • The role of lipids was established by Kannel et al , 1 who demonstrated correlations between the concentrations of serum cholesterol and the major lipoprotein classes at entry to the study and the development of CHD during the subsequent 14 years. (bmj.com)
  • The incidence of CHD during follow-up was found to be threefold greater in subjects with serum cholesterol and VLDL and LDL concentrations in the top versus the bottom quartile, but apart from a raised VLDL in postmenopausal women, measurement of lipoprotein fractions was no more predictive than serum cholesterol alone. (bmj.com)
  • The main exception was HDL cholesterol, which was shown in a subsequent analysis of Framingham data to correlate even more strongly than LDL cholesterol with risk of CHD, but inversely. (bmj.com)
  • The increase of low-density lipoprotein cholesterol (LDL-C) is widely accepted as an important factor in the occurrence of atherosclerosis. (biomedcentral.com)
  • In recent years, the guidelines have recommended non-high density lipoprotein cholesterol (non-HDL-C) as a secondary target for lipid-lowering therapy. (biomedcentral.com)
  • In the test group, total cholesterol (TC), triglycerides (TG), LDL-C, high density lipoprotein cholesterol (HDL-C), non-HDL-C, arteriosclerosis index (AI), and LDL-C/HDL-C all correlated with the patients' Gensini score. (biomedcentral.com)
  • The main indicators included in the blood lipid profile are TG, TC, HDL-C, LDL-C, very low-density lipoprotein cholesterol (VLDL-C), etc. (biomedcentral.com)
  • According to a widely accepted hypothesis, HDL or its subtractions play an important role in recruiting and transporting cholesterol from peripheral tissues to the liver for excretion, a series of events known as reverse cholesterol transport [ 2 ]. (biomedcentral.com)
  • When HDL is oxidatively modified, it alters to a form that causes macrophages to accumulate cholesterol. (biomedcentral.com)
  • Oxidatively modified HDL is no longer capable of removing cholesterol from cells, and it enhances LDL oxidation [ 8 ]. (biomedcentral.com)
  • However, after adjustments for age and body mass index, a significant correlation between total cholesterol level and serum LH/FSH ratio was observed (r=0.221, P =0.018). (ogscience.org)
  • Even after adjustment for gender, fat mass%, MAP, HDL cholesterol and triglycerides, cfPWV was higher in group 2 than group 1. (dovepress.com)
  • In a logistic binary regression on the entire population, considering subclinical vascular damage as a dependent variable and age, gender, MAP, fat mass%, triglycerides, HDL cholesterol and category of subjects with high leptin and low adiponectin as independent variables, MAP and category of subjects with high leptin and low adiponectin were significant predictors (OR, respectively, 1.09 and 3.61). (dovepress.com)
  • Independent risk assessment tests such as sdLDL Cholesterol and Lipoprotein(a) to determine any genetic factors which may increase their risk of CVD. (randox.com)
  • Scientists are investigating any kind of correlation between modest wine consumption plus a healthy amount of high-density lipoproteins (HDL, or the "good" cholesterol) in the bloodstream. (customproducttraining.com)
  • Objectives To characterize lipids and lipoproteins inside a diverse school-based cohort and identify features associated with discordance between low-density lipoprotein cholesterol (LDL-C) and LDL particle (LDL-P). of LDL-C and LDL-P discordant by >20 percentile devices an amount reasoned to be clinically significant were compared. (biopaqc.com)
  • 1116 (46.8%) children had LDL-P and LDL-C ideals within 12 percentile devices almost identical to the 50% reported for adults inside a multi-ethnic human population.9 LDL-C exceeded LDL-P by >20 percentile units in 428 (18.0%) participants identifying a group of children with relatively cholesterol-rich lipoprotein particles. (biopaqc.com)
  • Angiopoietin-like protein 3 (ANGPTL3) is a major lipoprotein regulator and shows positive correlation with high-density lipoprotein-cholesterol (HDL-c) in population studies and ANGPTL3 mutated subjects. (biomedcentral.com)
  • After adjustment for body mass index, triglycerides, HDL cholesterol and adiponectin, FGF21 levels showed a significant correlation with only HOMA-IR on multivariate linear regression analysis. (jomes.org)
  • Disease activity (DAS28) and plasma lipoproteins concentrations (total, HDL and LDL-cholesterol, triglycerides, ApoA, ApoB) were assessed in 55 RA patients and 55 controls. (bmj.com)
  • During therapy, the changes in disease activity and inflammatory status were inversely correlated with changes in plasma total and HDL cholesterol levels and positively correlated with the variation of atherogenic index. (bmj.com)
  • 1 Among the traditional cardiovascular risk factors, the lipid profile in RA has often been described as "pro-atherogenic", 2 based on decreased HDL-cholesterol (HDL-C) and increased LDL:HDL-C ratio and lipoprotein (a) plasma concentrations in both active and treated RA. (bmj.com)
  • Compared to the non-Ari group, fasting blood glucose (FBG), blood uric acid (UA), total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-C) levels were significantly higher in the co-Ari group, but there was no difference in PRL levels. (frontiersin.org)
  • high density lipoprotein cholesterol (HDL-C) and FVII. (bvsalud.org)
  • Linear regression models examined the independent and joint associations of sedentary tasks with a composite cardiometabolic risk score, as well as with individual cardiometabolic risk factors (waist circumference, blood pressure, fasting glucose, insulin, triglycerides, and high density lipoprotein cholesterol) after adjusting for physical activity and other covariates. (medscape.com)
  • Nevertheless, as all potentially atherogenic lipoprotein particles contain only one molecule of apoB and various amounts of cholesterol, apoB is a better marker of atherogenic particle numbers. (medscape.com)
  • The lipid abnormalities, which include hypercholesterolemia (decreased high-density lipoprotein [HDL] cholesterol and increased low-density lipoprotein [LDL] cholesterol), together with the characteristic hypertriglyceridemia do not cause premature atherosclerotic lesions in affected individuals. (medscape.com)
  • Taking blond psyllium by mouth reduces low density lipoprotein (LDL or "bad") cholesterol in people with mild to moderate high cholesterol. (medlineplus.gov)
  • According to NCEP ATP III, an individual should be considered as having MS when he or she presents at least three of the following factors: visceral obesity, hypertriglyceridemia, HDL (reduced cholesterol), altered hypertension and fasting glycemia 27 . (bvsalud.org)
  • IIn the 5,830 individuals aged 20 to 70 who were evaluated, dietary GI and GL were significantly associated with HDL-C, LDL-C, LDL-C/HDL-C ratio, and triglycerides serum levels. (hindawi.com)
  • Triglycerides in intermediate-density lipoprotein (IDL-TG) increased only in the CBCR group (p = 0.043). (biosferteslab.com)
  • In contrast, high-density lipoprotein (HDL) is usually decreased, especially when triglycerides are raised. (bmj.com)
  • Triglycerides and HDL are significant indicators of cardiovascular health. (regenxhealth.com)
  • triglycerides and HDL-C using the Friedewald formula. (bvsalud.org)
  • It is defined by the presence of visceral obesity, elevated triglycerides, decreased HDL, elevated blood pressure and blood glucose. (bvsalud.org)
  • Correlates of serum lipids and lipoproteins in Congolese patients with arterial hypertension. (bvsalud.org)
  • The purpose of this study was to assess the prevalence of dyslipidaemia and the correlates of serum lipids and lipoproteins among Congolese subjects with and without arterial hypertension . (bvsalud.org)
  • Associations between continuous variables were assessed with Pearson correlation coefficients, and correlates of lipids and lipoproteins were determined using multiple linear- regression analysis . (bvsalud.org)
  • Correlation analysis of individual variation of controls and index case relatives indicates a substantial level of independence between the major lipoprotein fractions. (bmj.com)
  • The triglyceride-to-HDL (TG/HDL) ratio decreased only in the CTR group (p = 0.006). (biosferteslab.com)
  • HDL components including apolipoprotein A-I (apoA-I), triglyceride, serum amyloid A (SAA), phospholipid and Sphingosine-1-phosphate were measured. (biomedcentral.com)
  • These fatty acids are transported to the liver, where they are used for triglyceride synthesis and are exported as very-low-density lipoprotein (VLDL), which is elevated in these patients. (medscape.com)
  • The likelihood of developing its cardiovascular consequences, especially coronary heart disease (CHD), is enhanced by dyslipidaemia, which manifests itself either as an increase in low-density lipoprotein (LDL), resulting in hypercholesterolaemia, or in very-low-density lipoprotein (VLDL), resulting in either hypertriglyceridaemia or, if VLDL remnants accumulate, mixed hyperlipidaemia. (bmj.com)
  • In male survivors of infarction there is a significant negative regression of VLDL and a significant positive regression of HDL on peak aspartate aminotransferase activity in blood samples taken within 24 hours of the incident. (bmj.com)
  • There are positive correlations between VLDL, IDL, and LDL, though when IDL is held constant by multiple regression, the correlation between VLDL and LDL is removed. (bmj.com)
  • From the pooled regression on single parents, heritabilities for HDL, LDL, and VLDL work out at 0·67 ± 0·21, 0·36 ± 0·18, and 0·23 ± 0.20, respectively. (bmj.com)
  • The lower heritability of VLDL is consistent with the variance of repeat measurements on the same control individuals, which is much higher for VLDL than for LDL or HDL. (bmj.com)
  • The high correlation between VLDL and measures of fatness, for which heritability estimates are statistically insignificant, as well as the association between raised VLDL concentration and smoking, also provide confirmatory evidence of the major importance of non-genetic causes in the variation of VLDL. (bmj.com)
  • Another factor of CVD that is often overlooked involves the concentrations of low-density lipoproteins (LDL) and very low-density lipoproteins (VLDL). (wikipedia.org)
  • 0.05), whereas in the post-menopausal women, no correlation was evident for the lumbar sites. (who.int)
  • 0.05), LDL-C/HDL-C had the most correlation with the patient's Gensini score. (biomedcentral.com)
  • A class of lipids known as phospholipids help make up what is known as lipoproteins, and a type of lipoprotein is called high density lipoprotein (HDL). (wikipedia.org)
  • High-density lipoprotein (HDL) was negatively correlated with cSVD burden ( ρ = -0.21, P = 0.02). (qxmd.com)
  • whereas high-density lipoprotein (HDL) was decreased. (researchsquare.com)
  • Oxidative modification of low-density lipoprotein (LDL) is a key event in the oxidation hypothesis of atherogenesis. (biomedcentral.com)
  • Some in vitro experiments have previously suggested that high-density lipoprotein (HDL) co-incubated with LDL prevents Cu 2+ -induced oxidation of LDL, while some other studies have observed an opposite effect. (biomedcentral.com)
  • Epidemiological studies show an inverse correlation between high-density lipoprotein (HDL) concentration and the risk of developing coronary artery disease [ 1 ]. (biomedcentral.com)
  • 12) reported a negative correlation between BMI and serum 25-hydroxy-vitamin D [25(OH) D] concentration, whereas Baradaran et al. (e-apem.org)
  • When the isolated LDL was subjected to Cu 2+ -induced oxidation, both HDL 2 and HDL 3 particles increased the rate of appearance and the final concentration of conjugated dienes similarly in both genders. (biomedcentral.com)
  • A larger waistline showed a significant correlation with testosterone deficiency. (regenxhealth.com)
  • Men had smaller LDL size and smaller concentrations of serum HDL and apoA-I than women. (biomedcentral.com)
  • At week 24, positive correlations were found between CCL2 and CXCL7 levels and LDL-C levels ( P =0.001 for each). (naturalmedicinejournal.com)
  • Findings were interpreted using pearson correlation coefficient and linear regression with commonality analysis. (biomedcentral.com)
  • The correlations between the LH/FSH ratio and various metabolic parameters were evaluated using Pearson correlation coefficients. (ogscience.org)
  • A Pearson unadjusted correlation analysis and a linear regression analysis adjusting for age, body mass index and lipid lowering drugs were performed in male or female non-diabetic participants or diabetic patients, respectively. (biomedcentral.com)
  • Compared to ratios of non-HDL-C and LDL-C, the LDL-C/HDL-C ratio in patients with STEMI is more correlated with the severity of coronary artery disease. (biomedcentral.com)
  • Correlation analysis revealed no significant correlations between serum LH/FSH ratios and biochemical parameters related to insulin resistance. (ogscience.org)
  • The fatty acid compositions of ultracentrifugally isolated LDL, HDL 2 and HDL 3 fractions were analyzed by gas liquid chromatography (Table 2 ). (biomedcentral.com)
  • Spearman correlation analysis indicated that hypertension was positively correlated with cSVD burden ( ρ = 0.21, P = 0.07). (qxmd.com)
  • A high concentration of high density lipoproteins-cholesterols (HDL-C) have what is known as a vasoprotective effect on the body, a finding that correlates with an enhanced cardiovascular effect. (wikipedia.org)
  • The Framingham Heart Study and other epidemiological studies have found a correlation between lipoproteins and cardiovascular disease (CVD). (wikipedia.org)
  • Correlations between miR-222-3p and glycolipid metabolic indicators and diabetic and cardiovascular complications in PCOS were analyzed. (biomedcentral.com)
  • Many laboratory, prospective and interventional studies have proven that apoB is a better indicator of cardiovascular risk than LDL-C. Statins lower LDL-C and non-HDL-C more (and to lower population percentile levels) than apoB. (medscape.com)
  • We hypothesised that prolonged telerehabilitation could also improve proinflammatory status and lipoprotein particle composition. (biosferteslab.com)
  • HDL shows no significant difference. (bmj.com)
  • Comparing the groups, there were also significant differences in the HDL-C ( P =0.036) and LDL-C levels ( P =0.030) at 24 weeks. (naturalmedicinejournal.com)
  • Further analysis showed that there was a significant correlation between the above differences in gut microbiota and inflammatory factors. (researchsquare.com)
  • The contradictory findings on the role of HDL on LDL oxidation in vitro may be due to rather small study populations, and the reported heterogeneity of oxidation kinetics between lipoprotein preparations in vitro [ 9 ] which might be due to individual intrinsic properties of the lipoproteins. (biomedcentral.com)
  • Production of the proteins, apolipoprotein A1 (ApoA1), the major component of HDL, and apolipoprotein B (ApoB), the main component of LDL, were studied. (chemistryviews.org)
  • As a result, many patients treated with statins to achieve LDL-C and non-HDL-C targets remain at high risk owing to high levels of apoB, especially subjects with the prevalence of small dense LDL. (medscape.com)
  • LDL-C experienced significantly higher BMI percentile waist circumference fasting insulin HOMA-IR and TG but lower TC LDL-C and HDL-C than both additional subgroups. (biopaqc.com)
  • The opposite characteristics lower BMI percentile waist circumference fasting insulin and HOMA-IR and TG but higher HDL-C also distinguished the LDL-P (biopaqc.com)
  • There is a strong correlation between hypertension and ED. There is also a correlation between benign prostatic hyperplasia and ED, though the causality is unclear. (medscape.com)
  • 3, besides having a strong correlation with Sleep from 7.8% in children9 to 55.8% in adolescents10, Disorders (SD). (bvsalud.org)
  • Likewise, the mean propagation rate and the maximum diene concentration increased significantly in the presence of HDL. (biomedcentral.com)
  • Correlation analysis was conducted to detect whether ABPM was associated with cSVD burden in AIS patients. (qxmd.com)
  • When cutoff value is 2.15, sensitivity is 0.845, and specificity is 0.202, LDL-C/HDL-C is an effective indicator for predicting whether patients with chest pain have STEMI. (biomedcentral.com)
  • However, no study has looked its correlation with HDL components nor with HDL function in patients with type 2 diabetes mellitus (T2DM). (biomedcentral.com)
  • The decrease of ANGPTL3 level in female T2DM patients might contribute to its weak association to HDL components and function. (biomedcentral.com)
  • But even as research on the relationship between LDL-C/HDL-C and atherosclerosis increases, it is still undetermined which index is most closely related to the severity of acute ST-segment elevation myocardial infarction (STEMI). (biomedcentral.com)
  • Later studies have confirmed that TG also causes atherosclerosis, while HDL-C has an anti-atherosclerotic effect [ 3 ]. (biomedcentral.com)
  • PCSK9 inhibitors are a new drug that can replace statins and lipoprotein apheresis therapy. (wikipedia.org)
  • There were no gender differences in the total amounts of saturated, monounsaturated and polyunsaturated fatty acids of LDL, HDL 2 and HDL 3 . (biomedcentral.com)
  • hypertriglyceridaemia (p=0.572) and low HDL-C (p=0.201). (bvsalud.org)
  • In later samples correlations were not evident. (bmj.com)
  • 0.0001) were correlations between LDL-P and non-HDL-C (r = 0.74) LDL-C (r = 0.66) and the TG/HDL-C percentage (r = 0.47) with inverse human relationships evident between LDL-P and both LDL size (r = ?0.48) and HDL size (r = ?0.64). (biopaqc.com)
  • The evidence for genetic variation in serum lipoprotein is based on the polygenic model and the analysis of the correlation between parents and offspring and the correlation between sibs. (bmj.com)
  • This study used openly available software and code, specifically LD-score regression [ https://github.com/bulik/ldsc/ ] (if we report genetic correlation), MiXer ( https://github.com/precimed/mixer ) and conjunctional FDR [ https://github.com/precimed/pleiofdr/ ]. (plos.org)
  • Spearman's correlation analysis revealed that serum creatine kinase levels were not correlated with body mass index, Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised score, or progression rate. (lww.com)
  • Independent t -test and multivariate correlation analysis were used to evaluate the relationship between FGF21 and metabolic parameters. (jomes.org)
  • this is based on correlation with not only the metabolic abnormalities of PCOS but also hyperandrogenism, either directly or indirectly via induction of inappropriate ovarian steroidogenesis [ 1 , 4 , 8 ]. (ogscience.org)
  • However, few studies have investigated the correlation between FGF21 levels and metabolic parameters in children. (jomes.org)