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  • percutaneous coronary int
  • Background- With the reduction in restenosis rates by drug-eluting stents, there is new controversy concerning the optimal management of incidental, nontarget lesions identified during percutaneous coronary intervention (PCI). (ahajournals.org)
  • Thus, focal prophylactic treatment of potentially vulnerable plaques is not performed because percutaneous coronary intervention (PCI) of intermediate lesions has been shown previously to have restenosis rates similar to those of PCI for symptom-causing lesions, thereby obviating the potential benefits of a prophylactic strategy. (ahajournals.org)
  • It is used in a procedure called percutaneous coronary intervention (PCI). (wikipedia.org)
  • Results demonstrate that it is in fact safe to administer the Ad-hHGF vector into patients with coronary artery disease in hopes of re-vascularizing damaged tissue in patients for which coronary artery bypass surgery (CABG) or percutaneous coronary intervention (PCI) are not available or possible. (wikipedia.org)
  • Percutaneous coronary intervention, however, involves the use of mechanical stents to increase blood flow to previously blocked (or occluded) vessels. (wikipedia.org)
  • If necessary, the physician can utilize percutaneous coronary intervention techniques, including the use of a stent (either bare-metal or drug-eluting) to open the blocked vessel and restore appropriate blood flow. (wikipedia.org)
  • Two major randomized controlled trials comparing CABG and DES are either completed or ongoing, and have published results - Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery (SYNTAX) and Future Revascularization Evaluation in Patients With Diabetes Mellitus-Optimal Management of Multivessel Disease (FREEDOM). (wikipedia.org)
  • clinical
  • 5,6 However, the incidence of clinical plaque progression in a large, contemporary cohort of patients treated with culprit vessel PCI and medical therapy for secondary prevention is unknown. (ahajournals.org)
  • There was no difference between the two study groups in clinical characteristics or in the coronary blood flow in the response to acetylcholine at baseline. (nih.gov)
  • Their course was correlated with data obtained during initial radionuclide testing, coronary arteriography, and clinical evaluation at study entry. (ahajournals.org)
  • A phase I clinical trial entailed injecting an adenovirus vector with the human HGF (Ad-hHGF) gene into the coronary vessels localized to ischemic tissue. (wikipedia.org)
  • therapeutic
  • 1. The digitalis derivatives, K -strophanthin, ouabain and digifoline at times have a direct coronary constrictor action even in therapeutic doses. (aspetjournals.org)
  • Thus, an understanding of the mechanisms of embryonic coronary vasculogenesis and angiogenesis may prove invaluable in developing novel strategies for cardiovascular regeneration and therapeutic coronary angiogenesis. (ox.ac.uk)
  • stent implantation
  • We retrospectively analyzed the results of 381 consecutive patients treated with Palmaz-Schatz coronary stent implantation between May 1992 and January 1996. (unimi.it)
  • vasoconstriction
  • 1 2 Endothelin-1, on the other hand, is an endothelium-derived peptide that produces coronary vasoconstriction at pathophysiological concentrations by binding to specific receptors on the vascular smooth muscle. (ahajournals.org)
  • Heart
  • Coronary artery anomalies (or malformation of coronary vessels) are congenital abnormalities in the coronary anatomy of the heart. (wikipedia.org)
  • The Congenital Heart Surgeons' Society has started a long-term ongoing study called anomalous aortic origin of a coronary artery (AAOCA) to identify the best way to treat this defect. (wikipedia.org)
  • The backwards pressure causes the aortic valve to shut, forcing the solution into the coronary vessels, which normally supply the heart tissue with blood. (wikipedia.org)
  • The left coronary artery distributes blood to the left side of the heart, the left atrium and ventricle, and the interventricular septum. (wikipedia.org)
  • This is because blockage of one coronary artery generally results in death of the heart tissue due to lack of sufficient blood supply from the other branch. (wikipedia.org)
  • There, he continued research, studying the chemistry of heart attacks, developing techniques for high-speed photography of the coronary vessels, and measurement of blood flow using nitric oxide. (wikipedia.org)
  • blood
  • Imaging devices operating within blood vessels can provide higher resolution images than devices used from outside the body because they can operate at higher frequencies. (medgadget.com)
  • But operating inside blood vessels requires devices that are small and flexible enough to travel through the circulatory system. (medgadget.com)
  • Invasive x-ray coronary angiography and bright-blood 2 3 coronary magnetic resonance angiography (MRA) only allow for assessment of luminal vessel diameter and do not provide direct information regarding coronary vessel wall thickness or atherosclerotic plaque. (ahajournals.org)
  • 8 9 T2-weighted black-blood fast spin-echo (TSE) techniques have been successfully applied for aortic 10 and carotid 11 vessel wall imaging. (ahajournals.org)
  • However, signal from slow-flowing blood in the laminar boundary layer adjacent to the vessel wall may mimic vessel wall signal and cause an overestimation of wall thickness/area. (ahajournals.org)
  • Endothelium-dependent coronary blood flow reserve to acetylcholine (10(-6) to 10(-4) mol/L) was assessed at baseline and after 6 months of therapy. (nih.gov)
  • This work extends PS-IR to PS-DIR and combined with spiral-imaging, multi-slice black-blood coronary vessel wall imaging is enabled in a single breath-hold. (biomedcentral.com)
  • To develop, and test a phase-sensitive DIR (PS-DIR) single-breath-hold multi-slice spiral black-blood coronary vessel wall imaging method. (biomedcentral.com)
  • Consequently, single-breath-hold multi-slice black-blood coronary vessel wall imaging is enabled using PS-DIR. (biomedcentral.com)
  • First, I want to talk about the function of blood vessels. (coursera.org)
  • of blood vessels, the architecture of the blood vessels and the histology. (coursera.org)
  • Now we saw that the blood vessel contain a lot of muscle cells. (coursera.org)
  • Angiogenesis is the process of growing new blood vessels. (blogspot.com)
  • Mural thrombi are thrombi that adhere to the wall of a blood vessel. (wikipedia.org)
  • A thrombus in a large blood vessel will decrease blood flow through that vessel (termed a mural thrombus). (wikipedia.org)
  • In a small blood vessel, blood flow may be completely cut off (termed an occlusive thrombus), resulting in death of tissue supplied by that vessel. (wikipedia.org)
  • Illustration Comparing Normal Artery vs Diseased Artery with a Blood Clot Micrograph showing a thrombus (center of image) within a blood vessel of the placenta. (wikipedia.org)
  • This drug is administered intravenously and can be used to dissolve blood clots in coronary vessels. (wikipedia.org)
  • It is critically important that the framework of the stent be in direct contact with the walls of the vessel to minimize potential complications such as blood clot formation. (wikipedia.org)