• Adults with SCAD will be identified both retrospectively and prospectively.Confirmation of the diagnosis by review of coronary angiography will be required before proceeding with the informed consent process and blood or saliva sample procurement. (clinicaltrials.gov)
  • BACKGROUND The transradial approach for percutaneous coronary procedures has the advantage of reduced access site complications but is associated with specific technical challenges in comparison with the transfemoral approach. (semanticscholar.org)
  • Increased Radial Access Is Not Associated With Worse Femoral Outcomes for Percutaneous Coronary Intervention in the United Kingdom. (semanticscholar.org)
  • 108 (7.0%) patients had a high-bifurcating radial origin, 35 (2.3%) had a full radial loop, 30 (2.0%) had extreme radial artery tortuosity and 39 (2.5%) had miscellaneous anomalies such as radial atherosclerosis and accessory branches. (semanticscholar.org)
  • Some mutations may be inherited (passed on) from a parent without an apparent blood vessel problem while others may develop for the first time in the affected person. (clinicaltrials.gov)
  • Multidetector CT provides a safe, accurate, noninvasive alternative to invasive coronary angiograms in a select patient population. (appliedradiology.com)
  • Multidetector CT will provide a safe, accurate, noninvasive imaging alternative to invasive coronary angiograms. (appliedradiology.com)
  • Receiver operating characteristic analysis was performed to describe the diagnostic performance of CT-FFR ≤ 0.80 in detecting interarterial R-ACAOS.RESULTS: Significant differences were found in proximal vessel morphology, take-off level, intramural course, % proximal narrowing area, and MLA at diastole (all p (bvsalud.org)
  • In this study, we describe defects in the formation of the coronary vasculature in the loop-tail ( Lp ) mutant in which the planar cell polarity (PCP) gene, Vangl2 , is disrupted. (ahajournals.org)
  • Conditional inhibition of myocardial Rho kinase activity disrupts the organization of the cardiomyocytes and formation of the coronary vessels to produce the same spectrum of defects as seen in Lp . These data suggest that Vangl2 and Rho kinase act cell autonomously in the myocardium to regulate the organization of cardiomyocytes but also have non-cell-autonomous effects on the formation of the coronary vasculature. (ahajournals.org)
  • Globally decreased FGF8 signaling during murine embryogenesis results in a hypomorphic phenotype with a constellation of heart, outflow tract, great vessel and pharyngeal gland defects that phenocopies human deletion 22q11 syndromes, such as DiGeorge. (biologists.org)