• Despite the use of Drug eluting stent (DES), the rate of restenosis remains 7% to 16% in diabetic patients, making it a challenging problem in interventional cardiology. (centerwatch.com)
  • This study evaluated the effect of lowering homocysteine on the rate of restenosis following PTCA with or without stents. (acc.org)
  • Many studies have shown that hyperinsulinemia and insulin resistance increase neointimal index measured six months after coronary stenting, and that insulin- sensitizers have beneficial effects by decreasing the rate of restenosis. (elsevier.com)
  • We designed a prospective, randomized, controlled study to verify the hypothesis that rosiglitazone, another member of the TZD class, reduces the rate of restenosis in type 2 diabetic patients who have undergone coronary stenting. (diabetesjournals.org)
  • Methods The ISAR-DESIRE 2 (Intracoronary Stenting and Angiographic Results: Drug Eluting Stents for In-Stent Restenosis 2) study was a randomized, open-label, active-controlled trial conducted among 450 patients with clinically significant in-SES restenosis at 2 centers in Munich, Germany. (onlinejacc.org)
  • Methods A total of 657 consecutive patients (age 63 ± 12 years, 79% men, 21% diabetics, 67% acute coronary syndrome) who received a total of 883 BRS for the treatment of coronary artery stenoses between May 2012 and January 2015 were enrolled in a retrospective registry. (onlinejacc.org)
  • Methods: As a substudy of the optimization with intracoronary, ultrasound (ICUS) to reduce stent restenosis (OPTICUS) study, we analyzed ACE serum levels and the ACE gene polymorphism in 154 patients at 9 different centers. (uni-muenchen.de)
  • Use of first generation DES versus BMS (OR 0.35, 95% CI 0.31 to 0.39) and second generation DES versus first generation DES (OR 0.67, 95% CI 0.58 to 0.77) were independent predictors of lower rates of restenosis. (bmj.com)
  • To evaluate the effect of adding cilostazol to dual antiplatelet therapy (aspirin and thienopyridine) on rates of restenosis after coronary artery stenting. (york.ac.uk)
  • Although many pharmacological therapies, such as conventional antiplatelet drugs, anticoagulants, and the like, have been investigated in an attempt to reduce restenosis, the majority of trials have been disappointing ( 8 - 11 ). (diabetesjournals.org)
  • This study was a prospective, randomized trial comparing the effect of cilostazol on restenosis with conventional antiplatelet therapy of aspirin. (ahajournals.org)